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      • AN EXPERT SYSTEM (SLALES) HIERARCHICAL CATEGORY-BASED FOR STUDENT TO LEARN ALGORITHM LANGUAGE

        Qun, Liu,Hua, Qiu Chang,Shan, Hua 대한전자공학회 1992 HICEC:Harbin International Conference on Electroni Vol.1 No.1

        A hierarchical category-based expert system (SLALES) has been developed to provide instruction tool, training environment for the student to learn BASIC, PASCAL language. The design of the SLALES is based on an innovative approach, which makes use of combining declarative representation with procedure representation and hierarchical pattern recognition. The content in knowledge has been expressed in the production rule, and yet they have been classified and organized in the light of inherent structure of knowledge. The inference is implemented by means of the rules and the structure.

      • KCI등재

        Insulin-positive ductal cells do not migrate into preexisting islets during pregnancy

        Liu Qun,Jiang Yinan,Zhu Lingyan,Qian Jieqi,Wang Chaoban,Yang Tianlun,Prasadan Krishna,Gittes George K.,Xiao Xiangwei 생화학분자생물학회 2021 Experimental and molecular medicine Vol.53 No.-

        The adult pancreatic ductal system was suggested to harbor facultative beta-cell progenitors similar to the embryonic pancreas, and the appearance of insulin-positive duct cells has been used as evidence for natural duct-to-beta-cell reprogramming. Nevertheless, the phenotype and fate of these insulin-positive cells in ducts have not been determined. Here, we used a cell-tagging dye, CFDA-SE, to permanently label pancreatic duct cells through an intraductal infusion technique. Representing a time when significant increases in beta-cell mass occur, pregnancy was later induced in these CFDA-SE-treated mice to assess the phenotype and fate of the insulin-positive cells in ducts. We found that a small portion of CFDA-SE-labeled duct cells became insulin-positive, but they were not fully functional beta-cells based on the in vitro glucose response and the expression levels of key beta-cell genes. Moreover, these insulin-positive cells in ducts expressed significantly lower levels of genes associated with extracellular matrix degradation and cell migration, which may thus prevent their budding and migration into preexisting islets. A similar conclusion was reached through analysis of the Gene Expression Omnibus database for both mice and humans. Together, our data suggest that the contribution of duct cells to normal beta-cells in adult islets is minimal at best.

      • Continuous supply of recycled Pacific oceanic materials in the source of Cenozoic basalts in SE China: the Zhejiang case

        Liu, Shao-Chen,Xia, Qun-Ke,Choi, Sung Hi,Deloule, Etienne,Li, Pei,Liu, Jia Springer-Verlag 2016 Contributions to mineralogy and petrology Vol.171 No.12

        <P>Various enriched recycled oceanic components in the source of Cenozoic intra-plate alkaline basalts from eastern China were identified by previous studies. Due to the existence of a stagnant subducted Pacific slab in the mantle transition zone beneath eastern China, it is logical to connect the stagnant slab to the recycled oceanic materials. However, the recycled oceanic materials could also result from ancient subduction events (e.g., Paleo-Tethyan, Paleo-Asian or Izanagi plate subduction) because enriched geochemical signatures of a recycled slab can be preserved in the mantle for longer than 1 Gyr. Investigating the temporal variations of the recycled oceanic materials in the mantle source is a useful way to trace the origin of the basalts. In this article, we have conducted a detailed geochemical study, including major and trace elements and Sr-Nd-Pb isotopes, on two alkaline basalt groups from Zhejiang, SE China, which erupted 26-17 Ma and after 11 Ma, respectively. In particular, we recovered the H2O content of the initial magmas based on the H2O content of the clinopyroxene (cpx) phenocrysts and the partition coefficients of H2O between cpx and basaltic melts. The H2O contents of the Zhejiang basalts range from 1.3 to 2.6 (wt.%), which fall within the range of back-arc basin or island arc basalts. The older basalts are more alkaline and have lower Si and Al contents; higher trace element concentrations; higher La/Yb, Ce/Pb and Nb/La ratios; lower H2O/Ce and Ba/Th ratios; and stronger negative K, Pb, Hf and Ti anomalies than the younger ones. The co-relationships between Ba/La, H2O/Ce, Nb/La, Ce/Pb and Ba/Th in the two groups of the Zhejiang basalts indicate that a recycled dehydrated oceanic alkaline basalt component is needed in the source of the older rocks, along with a depleted mantle component. Meanwhile, an additional recycled dehydrated sediment component was required in the source of the younger rocks. The temporal change in the recycled oceanic materials in the mantle sources of Zhejiang Cenozoic basalts demonstrates that the recycled components can only originate in the stagnant Pacific slab that is the only plate subducted since 100 Ma in this area.</P>

      • KCI등재

        The Clinical Characteristic and Management of Patients with Nocardiosis in a Tertiary Hospital in China

        Liu Peilin,Wang Zhiqian,Jian Zijuan,Liu Xuan,Li Yanming,Yan Qun,Zhong Baiyun,Liao Mengting,Liang Xianghui,Liu Wenen 한국미생물·생명공학회 2023 Journal of microbiology and biotechnology Vol.33 No.5

        Nocardiosis is an uncommon opportunistic bacterial infection which becomes a significant health problem due to its increasing incidence and high mortality rate. However, many nocardiosis patients are underdiagnosed by physicians. To summarize the clinical characteristics and management of nocardiosis would help with better diagnosis and prognosis of nocardiosis. This retrospective study was conducted based on the medical records of nocardiosis patients between January 2015 and December 2021 in a tertiary hospital in China. Overall, 44 nocardiosis patients with 54 specimens were included. The patients consisted of 26 males and 18 females with a mean age of 50.4 ± 13.2 years. Among 44 patients, 26 (59.1%) were previously given immunosuppressive therapy. Connective tissue diseases (CTDs) were the most common underlying disease (16/44). The most frequent infection sites were the lungs (17/44) and skin or soft tissues (8/44). Common symptoms included cough (23/44), expectoration (18/44), fever (15/44), and subcutaneous abscesses (15/44). Forty-five out of 54 specimens (83.3%) required over 48 hours of culture time for nocardiosis detection. Thirty-six patients were cured or improved, 5 patients were discharged from the hospital due to poor prognosis, and 1 patient died. The average diagnosis time of poor prognosis cases was 19.7 days, which was significantly longer than those of improved or cured patients (7.3 days). Immunosuppressed patients comprise a large part of nocardiosis cases, which is worth attention in clinical practice. Early diagnosis, specifically through prolonged cultivation time of specimen, could help achieve better prognosis of nocardiosis patients.

      • KCI등재

        Clearance Measurement Equipment for Gas Lubricated Dynamic Pressure Bearing of Gyro Motor

        Tong-qun Ren,Zhi-rou Liu,Xiang-dong Xu,Yu Liu,Xiaodong Wang 한국정밀공학회 2019 International Journal of Precision Engineering and Vol.20 No.12

        The clearance of gas lubricated dynamic pressure bearing of gyro motor refers specifically to small internal air gap between the rotor and stator. The clearance size is an important indicator of running performance of a motor. In this work, a dedicated clearance measurement equipment is developed. The clearance is converted to external micro displacement and measured by dual inductive probes with relative measurement principle. For this purpose, three main functional modules are designed together with corresponding electronic and pneumatic control systems. The clamp fixation module helps to support the measured bearing flexibly at the shaft end, which is conducive to protect the bearing and ensure the smoothness of force application. The force application module consists of a 3-D precision motion platform and a triaxial force sensor. It converts internal air gap to external micro displacement in cooperation with the clamp fixation module. The displacement measurement module is a 2-D precision motion platform carrying dual inductive probes. Based on theoretical analysis and practical experiments, the measurement accuracy is superior to 0.3 μm. Moreover, it realizes controllable and continuous force application, which is suitable for batch measurement.

      • The 2518 A/G Polymorphism in the MCP-1 Gene and Cancer Risk: A Meta-analysis

        Jia, Liu-Qun,Shen, Yong-Chun,Guo, Shu-Jin,Hu, Qian-Jing,Pang, Cai-Shuang,Wang, Tao,Chen, Lei,Wen, Fu-Qiang Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.6

        Background: The 2518 A/G polymorphism in the MCP-1 gene has been extensively studied for association swith cancer; however, results from replication studies have been inconsistent. The aim of this investigation was to determine links with risk of cancer by meta-analysis. Methods: We searched Pubmed, Embase, CNKI, Weipu and Wanfang databases, covering all case-control studies until March, 2013. Statistical analyses were performed using the Revman 5.0 software. Results: A total of 11 case-control studies met our inclusion criteria, including 1,422 cases and 2,237 controls. The results indicated that the MCP-1 2518 gene polymorphism had no association with cancer risk overall (GG vs.GA+ AA: OR = 0.89, 95%CI = 0.61-1.28, P = 0.52). However, in the subgroup analysis by ethnicity, a decrease of cancer risk was found in Asian populations (GG vs.GA+ AA: OR = 0.79, 95%CI = 0.63-0.99, P = 0.04). Conclusion: This meta-analysis suggested that the 2518A/G polymorphism of MCP-1 gene is associated with risk of cancer among Asian, but not in Caucasian populations.

      • KCI등재

        Structural Behavior of Steel Tube and Coupler Scaffolds with Stability Strengthening Details

        Hongbo Liu,Yi Meng,Li Jia,Zhihua Chen,Qun Liu,Suilin Wen 한국강구조학회 2018 International Journal of Steel Structures Vol.18 No.1

        The multi-span steel tube and coupler scaffold is one of the main temporary structural forms in building and bridge construction. Given the insufficient research on their bearing capacity and design method, steel tube and coupler scaffolds have frequently collapsed in recent years and have caused serious casualties and economic losses. Through six prototype tests and a numerical analysis, this study investigated the effect of stability strengthening measures, such as vertical X-bracing, horizontal X-bracing, surrounding non-loading area, and lateral wall-tied constraints, on the ultimate bearing capacity and failure mode of multi-span steel tube and coupler scaffolds under a uniformly distributed line load of upper horizontal tubes. Using the finite element numerical analysis verified by the test data, the influence of height-width ratio, structure height, story height, spacing of vertical tubes, X-bracing layout, lateral wall-tied constraints, and surrounding non-loading area on the ultimate bearing capacity of multi-span steel tube and coupler scaffolds was analyzed. Design methods for multi-span steel tube and coupler scaffolds under a uniformly distributed line load of upper horizontal tubes were proposed based on the results of the prototype test and finite element numerical analysis. The reasonability of the design method was verified by the test data and finite element analysis results.

      • KCI등재

        『文始』初文,准初吻文的來源構成

        ( Li Qun Liu ) 한국한자한문교육학회 2014 漢字 漢文敎育 Vol.33 No.-

        『문시(文始)』중의 초문(初文)과 준초문(准初文)에 대해 장태염(章太炎)은 동원(同源) 계열의 시작점으로 보고 있으며, 이것이 전체 저서의 핵심 개념 중 하나이다. 얼마전까지 학계에서는 『문시』의 초문, 준초문의 유래와 성격에 대해 여전히 쟁론이 이어졌다. 본문은 정량적 분석과 정성적 연구를 결합하는 방법을 이용하여 『문시』중의 초문과 준초문의 주요 유래가 『설문해자』에 수록된 고문자형이며, 일부분에 있어서 기타 고문자 자료에서 유쾌함을 밝힘으로 『문시』의 초문과 준초문의 구성 유래를 면확히 하고 초문과 준초문의 성격에 대해 논의하면서, 우리가 객관적 자세로 장태염의 고문자를 인식관을 이해하도록 하였다. Wenshi, written by Zhang Taiyan, is an important work in the history of Chinese etymology. As the core conception of this bookmaking, The question of Chuwen`s source brought some controversy in the academia. Through a survey on Chuwen in Wenshi, this paper proves that most of Chuwen come from ShuoWen, and a small amount of Chuwen come from other ancient writing materials.A clear understanding on the source of Chuwen, not only helps to research the essential of Chuwen, but also helps to understand Zhang`s attitude to excavated writing materials.

      • SCIESCOPUSKCI등재

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