Transformational Leadership and Innovation Capability: Roles of Knowledge-centered Culture and Knowledge Sharing

Phong Ba LE(Phong Ba LE ),Thanh Trung LE(Thanh Trung LE ) 한국유통과학회 2023 The Journal of Asian Finance, Economics and Busine Vol.10 No.1

Given the gaps in the link between leadership, knowledge resource, and innovation capability, this study aims to examine the potential mediating role of knowledge sharing and moderating role of knowledge-centered culture in the relationship between transformational leadership and a firm’s capability for innovation. This study applied the Structural Equation Modeling to try out proposal hypotheses in the research model through a questionnaire survey from a sample of 301 participators in 115 small and medium firms in the field of tourism and hotel. The findings disclosed that knowledge-sharing behaviors significantly mediate the transformational leadership-innovation relationship. It highlights the significant impact of explicit knowledge sharing in comparison with the influence of tacit knowledge sharing on innovation capability. The paper also reveals the crucial role of knowledge-centered culture in boosting the knowledgesharing- innovation relationship. By exploring the mediating role of knowledge sharing and the moderator of knowledge-centered culture, the paper significantly brings insight into different mediating and moderating mechanisms to improve innovation capability. The paper significantly fills up the gaps and provides valuable initiatives on the mechanism of how transformational leadership and specific forms of knowledge-sharing behaviors positively affect innovation capability under the moderating role of knowledge-centered culture.

Bioactive triterpene glycosides from the fruit of <i>Stauntonia hexaphylla</i> and insights into the molecular mechanism of its inflammatory effects

Ba Vinh, Le,Jang, Hyun-Jae,Viet Phong, Nguyen,Dan, Gao,Won Cho, Kyoung,Ho Kim, Young,Young Yang, Seo Pergamon Press 2019 Bioorganic & medicinal chemistry letters Vol.29 No.16

<P><B>Abstract</B></P> <P>Chromatography of the ethanol extract of the medicinal fruit <I>Stauntonia hexaphylla</I> resulted in the purification of 26 compounds (<B>1</B>–<B>26</B>), including two undescribed triterpene saponins <B>1</B> and <B>2</B> (hexaphylosides A and B). Their structures were confirmed by spectroscopic data, including IR, HR QTOF MS, <SUP>1</SUP>H, <SUP>13</SUP>C NMR, COSY, HMQC, HMBC, and TOCSY, and HPLC sugar analysis after acid hydrolysis. The anti-inflammatory effects of the high-purity constituents (<B>1</B>–<B>26</B>) on lipopolysaccharide (LPS)-induced RAW264.7 macrophage cells were investigated by screening nitric oxide production. The NO inhibitory activity of compounds <B>6</B> and <B>10</B> with the IC<SUB>50</SUB> values of 1.33 and 1.10 µM, respectively. The structure-activity relationships (SAR) of the isolated compounds were also analyzed. Furthermore, compounds <B>6</B> and <B>10</B> inhibited the protein expression inducible nitric oxide synthase (iNOS), and cyclooxygenase (COX)-2 via Western blotting analysis. This showed that compounds <B>6</B> and <B>10</B> contributed to the anti-inflammatory effects of <I>S</I>. <I>hexaphylla</I> fruit, which could be developed as a natural nutraceutical and functional food ingredient.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Two new triterpene saponins <B>1</B> and <B>2</B> were established by unambiguously spectroscopic methods and chemical reaction. </LI> <LI> The ethanol extract, fractions, and isolated compounds showed significant NO inhibitory activities. </LI> <LI> Compounds <B>6</B> and <B>10</B> inhibited iNOS and COX-2 expression. </LI> <LI> The <I>S. hexaphylla</I> fruit could be developed as a natural nutraceutical and functional food ingredient. </LI> </UL> </P> <P><B>Graphic abstract</B></P> <P>[DISPLAY OMISSION]</P>

Spatial Interpolation and Assimilation Methods for Satellite and Ground Meteorological Data in Vietnam

( Khac Phong Do ),( Ba Tung Nguyen ),( Xuan Thanh Nguyen ),( Quang Hung Bui ),( Nguyen Le Tran ),( Thi Nhat Thanh Nguyen ),( Van Quynh Vuong ),( Huy Lai Nguyen ),( Thanh Ha Le ) 한국정보처리학회 2015 Journal of information processing systems Vol.11 No.4

This paper presents the applications of spatial interpolation and assimilation methods for satellite and ground meteorological data, including temperature, relative humidity, and precipitation in regions of Vietnam. In this work, Universal Kriging is used for spatially interpolating ground data and its interpolated results are assimilated with corresponding satellite data to anticipate better gridded data. The input meteorological data was collected from 98 ground weather stations located all over Vietnam; whereas, the satellite data consists of the MODIS Atmospheric Profiles product (MOD07), the ASTER Global Digital Elevation Map (ASTER DEM), and the Tropical Rainfall Measuring Mission (TRMM) in six years. The outputs are gridded fields of temperature, relative humidity, and precipitation. The empirical results were evaluated by using the Root mean square error (RMSE) and the mean percent error (MPE), which illustrate that Universal Kriging interpolation obtains higher accuracy than other forms of Kriging; whereas, the assimilation for precipitation gradually reduces RMSE and significantly MPE. It also reveals that the accuracy of temperature and humidity when employing assimilation that is not significantly improved because of low MODIS retrieval due to cloud contamination.

Spatial Interpolation and Assimilation Methods for Satellite and Ground Meteorological Data in Vietnam

Do, Khac Phong,Nguyen, Ba Tung,Nguyen, Xuan Thanh,Bui, Quang Hung,Tran, Nguyen Le,Nguyen, Thi Nhat Thanh,Vuong, Van Quynh,Nguyen, Huy Lai,Le, Thanh Ha Korea Information Processing Society 2015 Journal of information processing systems Vol.11 No.4

This paper presents the applications of spatial interpolation and assimilation methods for satellite and ground meteorological data, including temperature, relative humidity, and precipitation in regions of Vietnam. In this work, Universal Kriging is used for spatially interpolating ground data and its interpolated results are assimilated with corresponding satellite data to anticipate better gridded data. The input meteorological data was collected from 98 ground weather stations located all over Vietnam; whereas, the satellite data consists of the MODIS Atmospheric Profiles product (MOD07), the ASTER Global Digital Elevation Map (ASTER DEM), and the Tropical Rainfall Measuring Mission (TRMM) in six years. The outputs are gridded fields of temperature, relative humidity, and precipitation. The empirical results were evaluated by using the Root mean square error (RMSE) and the mean percent error (MPE), which illustrate that Universal Kriging interpolation obtains higher accuracy than other forms of Kriging; whereas, the assimilation for precipitation gradually reduces RMSE and significantly MPE. It also reveals that the accuracy of temperature and humidity when employing assimilation that is not significantly improved because of low MODIS retrieval due to cloud contamination.

Spatial Interpolation of Meteorologic Variables in Vietnam using the Kriging Method

( Xuan Thanh Nguyen ),( Ba Tung Nguyen ),( Khac Phong Do ),( Quang Hung Bui ),( Thi Nhat Thanh Nguyen ),( Van Quynh Vuong ),( Thanh Ha Le ) 한국정보처리학회 2015 Journal of information processing systems Vol.11 No.1

This paper presents the applications of Kriging spatial interpolation methods for meteorologic variables, including temperature and relative humidity, in regions of Vietnam. Three types of interpolation methods are used, which are as follows: Ordinary Kriging, Universal Kriging, and Universal Kriging plus Digital Elevation model correction. The input meteorologic data was collected from 98 ground weather stations throughout Vietnam and the outputs were interpolated temperature and relative humidity gridded fields, along with their error maps. The experimental results showed that Universal Kriging plus the digital elevation model correction method outperformed the two other methods when applied to temperature. The interpolation effectiveness of Ordinary Kriging and Universal Kriging were almost the same when applied to both temperature and relative humidity.

A New Ceanothane-Type Triterpenoid Saponin Isolated from Gouania leptostachya DC. var. tonkinensis Pit. and Its Underlying Anti-Inflammatory Effects

( Nguyen Thi Hang ),( Nguyen Thi Bich Thu ),( Le Ba Vinh ),( Nguyen Viet Phong ),( Tran Van On ),( Ki Yong Lee ) 한국미생물생명공학회 2023 Journal of microbiology and biotechnology Vol.33 No.7

Metabolites from medicinal plants continue to hold significant value in the exploration and advancement of novel pharmaceuticals. In the search for plants containing compounds with anti-inflammatory effects, we observed that the ethanol (EtOH) extract obtained from the aerial components of Gouania leptostachya DC. var. tonkinensis Pit. exhibited substantial suppression of nitric oxide (NO) in vitro. In a phytochemical study on an EtOH extract of G. leptostachya, 11 compounds were purified, including one unreported compound namely gouanioside A (1). Their chemical structures were unambiguously determined through the use of various spectroscopic techniques, such as 1 and 2D NMR, IR, and HR-ESI-MS, and by producing derivatives via chemical reactions. The EtOH extract, fractions, and a new compound exerted inflammatory effects by altering NO synthesis in murine RAW264.7 macrophage cells stimulated with lipopolysaccharide. The underlying inflammatory mechanism of the new compound 1 was also explored through various in vitro experiments. The results of this study indicate the potential usefulness of new compound 1 from G. leptostachya as a treatment for inflammatory diseases.