Mental Health Among Healthcare Workers During the COVID-19 Pandemic in Vietnam

Nhan Phuc Thanh Nguyen,Ha Phan Ai Nguyen,Cao Khoa Dang,Minh Tri Phan,Huynh Ho Ngoc Quynh,Van Tuan Le,Chinh Van Dang,Tinh Huu Ho,Van Trong Phan,Van Trong Phan,Thang Phan,Dang Thi Anh Thu 대한예방의학회 2024 예방의학회지 Vol.57 No.1

Objectives: The objective of this study was to characterize mental health issues among Vietnamese healthcare workers (HCWs) and to identify related factors.Methods: A cross-sectional study was conducted with 990 HCWs in 2021. Their mental health status was measured using the Depression, Anxiety, and Stress Scale.Results: In total, 49.9%, 52.3%, and 29.8% of respondents were found to have depression, anxiety, and stress, respectively. The multivariable linear regression model revealed that factors associated with increased anxiety scores included depression scores (β, 0.45; 95% confidence interval [CI], 0.39 to 0.51) and stress scores (β, 0.46; 95% CI, 0.41 to 0.52). Factors associated with increased depression scores included being frontline HCWs (β, 0.57; 95% CI, 0.10 to 1.10), stress scores (β, 0.50; 95% CI, 0.45 to 0.56), and anxiety scores (β, 0.41; 95% CI, 0.36 to 0.47), while working experience was associated with reduced depression scores (β, -0.08; 95% CI, -0.16 to -0.01). Factors associated with increased stress scores included working experience (β, 0.08; 95% CI, 0.00 to 0.16), personal protective equipment interference with daily activities (β, 0.55; 95% CI, 0.07 to 1.00), depression scores (β, 0.54; 95% CI, 0.48 to 0.59), and anxiety scores (β, 0.45; 95% CI, 0.39 to 0.50), while age was associated with reduced stress scores (β, -0.12; 95% CI, -0.20 to -0.05).Conclusions: Specific interventions are necessary to enhance and promote the mental health of HCWs so they can successfully cope with the circumstances of the pandemic.

Anti-inflammatory tirucallane saponins from Paramignya scandens.

Phan, Nguyen Huu Toan,Thuan, Nguyen Thi Dieu,Ngoc, Ninh Thi,Thao, Nguyen Phuong,Kim, Sohyun,Koh, Young Sang,Thanh, Nguyen Van,Cuong, Nguyen Xuan,Nam, Nguyen Hoai,Kiem, Phan Van,Kim, Young Ho,Minh, Cha Pharmaceutical Society of Japan 2015 Chemical & pharmaceutical bulletin Vol.63 No.7

<P>Five new tirucallane saponins, paramignyosides A-E (1-5), were isolated from the water fraction of the Paramignya scandens stem and leaves. Their structures were elucidated on the basis of spectroscopic evidence including high-resolution electrospray ionization mass spectrometry (HR-ESI-MS) and one dimensional (1D)- and 2D-NMR. The effects of isolated compounds on pro-inflammatory cytokines were evaluated by measuring the production of interleukin (IL)-12 p40, IL-6, and tumor necrosis factor-α (TNF-α) in lipopolysaccharide (LPS)-stimulated bone marrow-derived dendritic cells (BMDCs). Paramignyoside C (3) exhibited selective and potent inhibitory effect (IC50=5.030.19??M) on the production of IL-12 p40 comparable to that of the positive control, SB203580 (IC50=5.000.16??M). Further studies are required to confirm efficacy in vivo and the mechanism of anti-inflammatory effects.</P>

Huge Tongue Base Neurilemmoma : Excision by Intraoral Coblation

김준선,phan huu ngoc minh,홍기환 대한이비인후과학회 부산,울산,경남 지부회 2016 임상이비인후과 Vol.27 No.2

Neurilemoma arising from the tongue base are very rare and only a few cases have been reported so far. The tumor is resistance to radiotherapy, and therefore, the treatment of choice is surgery. Diagnosis was confirmed by imaging studies and biopsy followed by surgical excision designed to preserve nerve function. We report a case of huge neurilemoma of the tongue base treated with intraoral coblation. Case reports and a review of the world literature concerning treatment methods and surgical approaches of neurilemoma of tongue base. A number of surgical approaches have been described for tongue base neurilemomas. We report a case of tongue base neurilemoma which was completely extirpated with a coblation through the intraoral approach. The postoperative course was uneventful and improved within 2 weeks like as tonsillectomy patient. The intraoral coblation assisted excision is a safe and useful surgical technique for the removal of tongue base neurilemoma.

Which Plosive Consonant Is More Useful for the Aerodynamic Analysis of Pathologic Voice?

홍용태,phan huu ngoc minh,홍기환 대한이비인후과학회 2020 Clinical and Experimental Otorhinolaryngology Vol.13 No.2

Objectives. Both acoustic and aerodynamic analyses are essential to evaluate the phonetic characteristics of voice pathology. The purpose of the study is to determine the magnitude of their correlation with the different types of bilabial plosive consonants. Methods. A controlled prospective study of 35 patients diagnosed with unilateral vocal fold paralysis was performed. The sustained vowel /a/ and bilabial voiceless consonants were used. Three common acoustic parameters were measured from a sustained vowel /a/ and aerodynamic parameters from a set of syllables /pi/, /phi/, and /p’i/. We determined the correlation coefficients between acoustic and aerodynamic measurements for the bilabial plosive consonants /pi/, /phi/, and /p’i/. Results. The mean values of acoustic parameters were higher than the thresholds of pathology. The mean values of aerodynamic parameters varied according to the types of consonants. The correlation between acoustic and aerodynamic parameters was significantly larger with the consonant /phi/ compared with the consonants /p’/ and /p/. The magnitudes of correlation were higher with the consonant /phi/ compared with the consonants /p’/ and /p/. Conclusion. The plosive consonant /phi/ may represent a more valuable investigative consonant than the consonants /p/ or/p’/ for aerodynamic analysis of voice pathology, especially in patients with unilateral vocal fold paralysis.

Phenothiazine Derivative as Organic Photocatalyst for Metal Free Atom Transfer Radical Polymerization

Hoan Minh Tran,Lan Ngoc Tan Phan,Thang Van Le,Thuy Thuy Truong,Tam Huu Nguyen,Khuong Tung Truong,Le-Thu T. Nguyen,Mai Thanh Phong,Ha Tran Nguyen 한국고분자학회 2019 폴리머 Vol.43 No.4

A novel organic photocatalyst, 4-(10H-phenothiazin-10-yl)-N,N-diphenylaniline (PDPA) has been successfully synthesized from triphenylamine and phenothiazine moiety via Buchwald-Hartwig C-N coupling. The chemical structure of catalyst was characterized via proton nuclear magnetic resonance (1H NMR) and the optical properties were investigated via UV-vis spectroscopy. The PDPA has been applied as an organic photocatalyst for metal free atom transfer radical polymerization (O-ATRP). The well-controlled molecular weights of polymethacrylates have been obtained with high yield of 95% and narrow polydispersity index (Đ).

An Unusual Metastasis of Posterior Neck and Axillary Lymph Nodes from Nasopharyngeal Carcinoma

홍용태(Yong Tae Hong),Phan Huu Ngoc Minh,홍기환(Ki Hwan Hong) 대한두경부종양학회 2016 대한두경부 종양학회지 Vol.32 No.2

비인강암은 비인강상피에 발생한 암으로 경부전이 및 간, 폐, 뼈 등의 원격전이가 흔히 나타난다. 본 증례에서는 제 4기 병기를 가진 비인강암환자에서 항암 화학요법 및 방사선 치료 후 매우 드물게 후경부 및 액와 림프절 전이를 보인 환자를 보고하는 바이다. 진행된 병기를 보이는 비인강암 환자는 방사선 치료 후 피부전이가 종종 나타나는 현상이나 후경부 림프절 전이는 흔치 않다. 특히 액와 림프절 전이는 비인강암에서 거의 전이를 보이지 않으나 본 증례에서는 매우 드물게 액와 림프절 전이를 보여 보고하는 바이다.

The Phonetic Characteristics in Patients of Bilateral Vocal Fold Paralysis Without Tracheotomy

홍용태,박민주,신유정,Phan Huu Ngoc Minh,홍기환 대한이비인후과학회 2017 Clinical and Experimental Otorhinolaryngology Vol.10 No.3

Objectives. Patients with bilateral vocal fold paralysis (BVFP) theoretically have difficulty producing voiceless consonants. However, perceptual studies have revealed clear production of voiceless consonants with good articulation scores in nontracheostomized patients. The purpose of this study was to clarify the production of voiceless stops during articulation in patients with BVFP compared to normal speakers. Methods. The perceptual, acoustic, and aerodynamic characteristics of patients with BVFP and those with normal speech were investigated with special reference to voiceless stop consonants. Test words were prepared to place the stop consonants in different phonological environments, and were all nonsense words. Results. The patients with BVFP perceptually produced the three types of stops successfully. However, they acoustically varied voice onset time to produce phonetically representative stops but decreased voice onset time of /ph/ and /p/ compared to those of normal speakers. These patients may properly control air pressure to produce the three types of stop consonants similar to normal speakers. Conclusion. The patients with BVFP realized the distinctions between the three types of stops similar to the normal speakers. Although vocal mobility was absent in the patients with BVFP, voice onset time, vowel duration, closure duration, and air pressure were similar to those of normal speakers.

α-Glucosidase Inhibition Properties of Cucurbitane-Type Triterpene Glycosides from the Fruits of <i>Momordica charantia</i>

Nhiem, Nguyen Xuan,Kiem, Phan Van,Minh, Chau Van,Ban, Ninh Khac,Cuong, Nguyen Xuan,Tung, Nguyen Huu,Ha, Le Minh,Ha, Do Thi,Tai, Bui Huu,Quang, Tran Hong,Ngoc, Tran Minh,Kwon, Young-In,Jang, Hae-Dong,K The Pharmaceutical Society of Japan 2010 Chemical & pharmaceutical bulletin Vol.58 No.5

<P>Fourteen cucurbitane-type triterpene glycosides (1—14) were isolated from a methanol extract of <I>Momordica charantia</I> fruits, including three new compounds, charantosides A—C (1, 5, 6). Their structures were elucidated by chemical and spectroscopic methods. All isolated compounds were evaluated for α-glucosidase inhibitory effect. Of which, 12 and 13 showed moderate inhibitory activity against α-glucosidase. Whereas, 2, 3, 6—11, and 14 showed weak inhibitory activity, and 1, 4, and 5 were inactive.</P>

식도음성의 모음종류에 따른 음향학적 특성

윤은미(Yun, Eunmi),목은희(Mok, Eunhee),판후응옥먼(Phan huu Ngoc Minh),홍기환(Hong, Kihwan) 한국음성학회 2015 말소리와 음성과학 Vol.7 No.4

This study aimed to establish characteristics related to voice and speech through the natural base frequency analysis of esophagus vocalization. In the study, 8 subjects were selected for esophagus vocals, and 10 other subjects were selected for a control group. MDVP(Multi-dimensional Voice Program, Model 4800, USA, 2001), Multi Speech(Model 3700, Kaypantax, USA, 2008) were used as experiment equipment. The speech samples selected for evaluation were vowels and sentences (both declarative and interrogative). For acoustic analysis, the intonation form of fo, jitter, energy, shimmer, HNR, and intonation patterns of the speech sample were measured. The results were as follows: First, the natural intrinsic frequency of extended vowels in the esophagus vocal group was lower than the frequency in the normal vocal group. In particular, the intrinsic frequency difference for high vowel /i/ was much greater than the frequency difference for low vowel /a/. Second, the jitter values of the esophagus vocal group were higher than the control group. In particular, there was a large difference between the jitter values for /a/ and /i/, with the jitter values being highest for /i/. Third, there was no significant difference in vocal strength between the esophagus vocal patient group and the control group. Fourth, the shimmer values of the voices in the esophagus vocal group were higher than shimmer values in the control group. In particular, there was a large difference in shimmer values for low vowel /a/. Fifth, the HNR values of the esophagus vocal group were showed significantly lower than the control group. In particular, the largest difference in HNR values between the two groups was for high vowel /i/. Sixth, the pitch contours of interrogative and declarative sentences of the esophagus vocal patient group showed a different form or only had with small differences compared to the pitch contours of the normal vocal group, thus presenting an inconsistent pattern.