푸른길 공원의 대기 환경 특성에 관한 연구

민경우,이경석,박옥현,윤관주,김도술,박세일,정원삼,이대행,조영관,Min, Kyoung-Woo,Lee, Kyoung-Soek,Park, Ok-Hyun,Yoon, Kwan-Ju,Kim, Do-Sool,Park, Se-Il,Jeung, Won-Sam,Lee, Dae-Hang,Cho, Young-Gwan 한국환경보건학회 2015 한국환경보건학회지 Vol.41 No.3

Objectives: This study aimed to survey the characteristics of air quality and meteorological conditions in a greenway park. Methods: We measured meteorological and health related factors, including noise, particulate matter ($PM_{10}$) and selected gaseous air pollutants at three locations in a greenway park and on a general roadside as comparison. The measurements were repeated four times from April to October 2014. Results: The average air temperature in the greenway park was $20.7^{\circ}C$ which was $1-2^{\circ}C$ lower than on the general roadside. The average $PM_{10}$ concentration in the greenway park was $85.0{\mu}g/m^3$, a level 2-3 times lower than that at the roadside. The noise level at the greenway site was 4.4 dB(A)- 23.0 dB(A) lower than at the roadside. The average CO, $CO_2$, $SO_2$ and NOx concentrations in the greenway park were lower than at the roadside. The average phytoncide and anions concentrations in the greenway park were higher than at the roadside. Conclusions: The urban forest of the greenway park may have some impact on air quality and meteorological conditions.

Electrical, Thermal, and Thermoelectric Transport Properties of Se-doped Polycrystalline Re2Te5

Se Woong Lee,Okmin Park,Hyun-Sik Kim,Won-Seon Seo,Sang-il Kim 대한금속·재료학회 2022 대한금속·재료학회지 Vol.60 No.12

Re2Te5 is considered a potential thermoelectric material because of its intrinsically low thermalconductivity, due to its complex crystal structure. Herein, a series of Se-doped Re2Te5 (Re2Te5-xSex, x = 0, 0.2,1, and 2) samples were synthesized, and their electrical and thermal transport properties were investigated. Pure orthorhombic Re2Te5 phases were successfully synthesized without any impurities for all compositions,and the continuous decrease in the calculated lattice parameters confirmed the substitution of Se atoms atthe Te sites. A maximum power factor of 0.135 mW/mK2was achieved for the sample with x = 0.2 at 880 K,mainly due to the increase in carrier concentration and electrical conductivity. The lattice thermalconductivity significantly decreased for all doped samples, which was attributed to the point defect phononscattering caused by Se doping. The thermoelectric figure of merit, zT reached a maximum value of 0.20 at880 K for Re2Te4.8Se0.2 (x = 0.2) sample, which was approximately 22% higher than that of the pristine Re2Te5sample. The weighted mobility, quality factor, and expected zT were calculated to evaluate the optimizationof the power factor and zT.

공급사슬에서 수량할인과 수익공유를 반영한 계약

박세호(Se Ho Park),이영해(Young Hae Lee),조동원(Dong Won Cho) 한국SCM학회 2012 한국SCM학회지 Vol.12 No.2

One of the most important reasons in pursuit of supply chain management is to prevent sub-optimization caused by decentralized decision making over the various entities. As supply chain coordination approach to overcome such a setting, contract mechanisms have frequently been used. However, a coordinated supply chain might fail to provide additional profit to one of the players. In result, it is necessary that a contract mechanism is designed to achieve the same profit in a centralized situation (coordination) and to improve the benefit of all the supply chain players (winwin). In this paper, we address supply chain contract based on revenue sharing and quantity discount considering price and service level. We show that the trade parameters among different entities in the supply chain contract can be chosen to achieve coordination and a win-win outcome.

Thermoelectric Properties of Cu-added Polycrystalline Bi2O2Se Oxyselenide

Si-young Bae,Se Woong Lee,Hyun-Sik Kim,Okmin Park,Hyunjin Park,Won-Seon Seo,Sang-il Kim 대한금속·재료학회 2022 대한금속·재료학회지 Vol.60 No.12

Bi2O2Se oxyselenide has been actively studied as a potential n-type thermoelectric material becauseof its intrinsically low thermal conductivity and high Seebeck coefficient (S). However, Bi2O2Se has very lowelectrical conductivity (σ), resulting in relatively poor thermoelectric performance. Herein, we investigate theeffect of Cu addition on the electrical and thermal transport of n-type polycrystalline Bi2O2Se. A series ofCuxBi2O2Se (x = 0, 0.0025, 0.005, and 0.0075) polycrystalline samples were synthesized by a conventional solid state reaction. Tetragonal Bi2O2Se was successfully synthesized, and its lattice parameters graduallydecreased with the addition of Cu. Further, σ decreased and the magnitude of S increased with increasingCu content, according to the trade-off relationship between these parameters. Consequently, a maximumpower factor of 0.106 mW m-1 K-2 was achieved for the sample with x = 0.0025 at 300 K, owing to the increasein the magnitude of S. The Hall carrier concentration decreased exponentially with the addition of Cu, whichis mainly attributed to the possible enlargement of the band gap of the Cu-added samples. The lattice thermalconductivity decreased with increasing x, which was attributed to point-defect phonon scattering via Cuaddition. Therefore, a maximum zT of 0.222 was obtained at 790 K for the Cu0.0025Bi2O2Se (x = 0.0025) sample,which was approximately 8% higher than that of the pristine Bi2O2Se sample.

Left Atrial Velocity Vector Imaging Can Assess Early Diastolic Dysfunction in Left Ventricular Hypertrophy and Hypertrophic Cardiomyopathy

Se-Jung Yoon,Sungha Park,Eui-Young Choi,Hye-Sun Seo,Chi Young Shim,Chul-Min Ahn,Sung-Ai Kim,Jong-Won Ha 한국심초음파학회 2023 Journal of Cardiovascular Imaging (J Cardiovasc Im Vol.31 No.1

BACKGROUND: The function of left atrium (LA) is difficult to assess because of its ventricle-dependent, dynamic movement. The aim of this study was to assess LA function using velocity vector imaging (VVI) and compare LA function in patients with hypertrophic cardiomyopathy (HCMP) and left ventricular hypertrophy (LVH) with normal controls. METHODS: Fourteen patients with HCMP (72% male, mean age of 52.6 ± 9.8), 15 hypertensive patients with LVH (88% male, mean age of 54.0 ± 15.3), and 10 age-matched controls (83% male, mean age of 50.0 ± 4.6) were prospectively studied. Echocardiographic images of the LA were analyzed with VVI, and strain rate (SR) was compared among the 3 groups. RESULTS: The e′ velocity (7.7 ± 1.1; 5.1 ± 0.8; 4.5 ± 1.3 cm/sec, p = 0.013), E/e′ (6.8 ± 1.6; 12.4 ± 3.3; 14.7 ± 4.2, p = 0.035), and late diastolic SR at mid LA (−1.65 ± 0.51; −0.97 ± 0.55; −0.82 ± 0.32, p = 0.002) were significantly different among the groups (normal; LVH; HCMP, respectively). The e′ velocity, E/e′, and late diastolic SR at mid LA were significantly different between normal and LVH (p = 0.001; 0.022; 0.018), whereas LA size was similar between normal and LVH (p = 0.592). The mean late diastolic peak SR of mid LA was significantly correlated with indices of diastolic function (E/e′, e′, and LA size). CONCLUSIONS: The SR is a useful tool for detailed evaluation of LA function, especially early dysfunction of LA in groups with normal LA size.

Synthetic Studies on Tedanolide:Stereoselective Synthesis of the C13-C21 Fragment

Park, Su-Ho,Min, Jae-Ki,Park, Se-Hwan,Lee, Hyo-Won Korean Chemical Society 2009 Bulletin of the Korean Chemical Society Vol.30 No.3

Relationship between ganglioside expression and anti-cancer effects of a plant-derived antibody in breast cancer cells

Won Seok Ju,Ilchan Song,Se-Ra Park,Sang Young Seo,Jin Hyoung Cho,Sung-Hun Min,Dae-Heon Kim,Ji-Su Kim,Sun-Uk Kim,Soon Ju Park,Kisung Ko,Young-Kug Choo 한국식물생명공학회 2019 JOURNAL OF PLANT BIOTECHNOLOGY Vol.46 No.3

Production of therapeutic monoclonal antibodies (mAbs) using a plant platform has been considered an alternative to the mammalian cell-based production system. A plant-derived mAb CO17-1AK (mAbP COK) can specifically bind to various types of cancer cell lines. The target protein of mAbP COK is the epithelial cell adhesion molecule (EpCAM) highly expressed in human epithelial cancer cells, including breast and colorectal cancer cells. It has been hypothesized that its overexpression supports tumor growth and metastasis. A ganglioside is extended well beyond the surfaces of the various cell membranes and has roles in cell growth, inflammation, differentiation, and carcinogenesis. However, the regulation of EpCAM gene expression in breast cancers and the role of gangliosides in oncogenesis are unclear. Here, the purpose of this study was to determine the effects of mAbP COK on human breast cancer cell proliferation, apoptosis, and ganglioside expression patterns. Our results show that treatment with mAbP COK suppressed the growth of breast cancer cells and induced apoptotic cell death. It also upregulated the expression of metastasis-related gangliosides in breast cancer cells. Thus, treatment with mAbP COK may have chemo-preventive therapeutic effects against human breast cancer.

Synthetic Studies on Soraphen A: Synthesis of the C1-C9 Hemiketal Segment

Park, Se-Hwan,Lee, Hyo-Won Korean Chemical Society 2008 Bulletin of the Korean Chemical Society Vol.29 No.8

A Study on Gasification Characteristics According to Feedstock (Solid Waste, Biomass, and Coal)

( Se-won Park ),( Sang-yeop Lee ),( Gun-ho Han ),( Yong-chil Seo ) 한국폐기물자원순환학회(구 한국폐기물학회) 2019 한국폐기물자원순환학회 심포지움 Vol.2019 No.1

One of the most important factors in the operation of the gasification process is the feedstock used. The main feedstock used in commercial gasification processes is coal, with some commercial scale gasification plants also using biomass and waste fuel. As noted above, the operation of the gasification process is difficult due to the complex chemical reactions involved. As a result, the optimal gasification conditions for each feedstock are different, and controlling these conditions is difficult. In particular, more basic data on gasification using biomass and waste fuels is needed compared with coal, which is actively operated by commercial gasification. Therefore, in this study, representative feedstocks from the three categories of feedstock that are mainly used in the gasification process were selected: coal was used for fossil fuels, sawdust was used for biomass, and fluff type SRF manufactured by MSW in Korea was used for waste fuel. Sawdust, fluff SRF, and coal were applied for a lab-scale fixed bed gasifier, which is relatively easy to operate. With respect to the data for coal gasification, this procedure mirrors the one used by references. This study examines the gasification characteristics according to each feedstock and ER. These are examined and the optimal conditions are derived.

Qualitative and Quantitative Magnetic Resonance Imaging Phenotypes May Predict CDKN2A/B Homozygous Deletion Status in Isocitrate Dehydrogenase-Mutant Astrocytomas: A Multicenter Study

Park Yae Won,Park Ki Sung,Park Ji Eun,Ahn Sung Soo,Park Inho,Kim Ho Sung,Chang Jong Hee,Lee Seung-Koo,Kim Se Hoon 대한영상의학회 2023 Korean Journal of Radiology Vol.24 No.2

Objective: Cyclin-dependent kinase inhibitor (CDKN)2A/B homozygous deletion is a key molecular marker of isocitrate dehydrogenase (IDH)-mutant astrocytomas in the 2021 World Health Organization. We aimed to investigate whether qualitative and quantitative MRI parameters can predict CDKN2A/B homozygous deletion status in IDH-mutant astrocytomas. Materials and Methods: Preoperative MRI data of 88 patients (mean age ± standard deviation, 42.0 ± 11.9 years; 40 females and 48 males) with IDH-mutant astrocytomas (76 without and 12 with CDKN2A/B homozygous deletion) from two institutions were included. A qualitative imaging assessment was performed. Mean apparent diffusion coefficient (ADC), 5th percentile of ADC, mean normalized cerebral blood volume (nCBV), and 95th percentile of nCBV were assessed via automatic tumor segmentation. Logistic regression was performed to determine the factors associated with CDKN2A/B homozygous deletion in all 88 patients and a subgroup of 47 patients with histological grades 3 and 4. The discrimination performance of the logistic regression models was evaluated using the area under the receiver operating characteristic curve (AUC). Results: In multivariable analysis of all patients, infiltrative pattern (odds ratio [OR] = 4.25, p = 0.034), maximal diameter (OR = 1.07, p = 0.013), and 95th percentile of nCBV (OR = 1.34, p = 0.049) were independent predictors of CDKN2A/B homozygous deletion. The AUC, accuracy, sensitivity, and specificity of the corresponding model were 0.83 (95% confidence interval [CI], 0.72–0.91), 90.4%, 83.3%, and 75.0%, respectively. On multivariable analysis of the subgroup with histological grades 3 and 4, infiltrative pattern (OR = 10.39, p = 0.012) and 95th percentile of nCBV (OR = 1.24, p = 0.047) were independent predictors of CDKN2A/B homozygous deletion, with an AUC accuracy, sensitivity, and specificity of the corresponding model of 0.76 (95% CI, 0.60–0.88), 87.8%, 80.0%, and 58.1%, respectively. Conclusion: The presence of an infiltrative pattern, larger maximal diameter, and higher 95th percentile of the nCBV may be useful MRI biomarkers for CDKN2A/B homozygous deletion in IDH-mutant astrocytomas.