푸른길 공원의 대기 환경 특성에 관한 연구

민경우,이경석,박옥현,윤관주,김도술,박세일,정원삼,이대행,조영관,Min, Kyoung-Woo,Lee, Kyoung-Soek,Park, Ok-Hyun,Yoon, Kwan-Ju,Kim, Do-Sool,Park, Se-Il,Jeung, Won-Sam,Lee, Dae-Hang,Cho, Young-Gwan 한국환경보건학회 2015 한국환경보건학회지 Vol.41 No.3

Objectives: This study aimed to survey the characteristics of air quality and meteorological conditions in a greenway park. Methods: We measured meteorological and health related factors, including noise, particulate matter ($PM_{10}$) and selected gaseous air pollutants at three locations in a greenway park and on a general roadside as comparison. The measurements were repeated four times from April to October 2014. Results: The average air temperature in the greenway park was $20.7^{\circ}C$ which was $1-2^{\circ}C$ lower than on the general roadside. The average $PM_{10}$ concentration in the greenway park was $85.0{\mu}g/m^3$, a level 2-3 times lower than that at the roadside. The noise level at the greenway site was 4.4 dB(A)- 23.0 dB(A) lower than at the roadside. The average CO, $CO_2$, $SO_2$ and NOx concentrations in the greenway park were lower than at the roadside. The average phytoncide and anions concentrations in the greenway park were higher than at the roadside. Conclusions: The urban forest of the greenway park may have some impact on air quality and meteorological conditions.

Regioselective Enzymatic Acylation of Multi-hydroxyl Compounds in Organic Synthesis

Park, Hyun-Gyu,Do, Jin-Hwan,Chang, Ho-Nam The Korean Society for Biotechnology and Bioengine 2003 Biotechnology and Bioprocess Engineering Vol.8 No.1

With current developments in enzyme-catalyzed reactions and techniques available for rational redesign of natural biocatalysts, the enzymatic biosynthesis can become one of the most valuable Synthetic methods. Enzymatic regioselective catalysis in organic media has played a key role in pursuing asymmetric synthesis for active chiral compounds. Here, we shortly do-scribe some historical issues of the rapidly growing area, enzymatic catalysis in synthetic organic chemistry and then review researches that have been carried out in the regioselective enzymatic catalysis for the past two decades. An application of this technology to the modification of some potential target drug co m pound will be adios presented.

국소성 분절성 사구체 경화증의 완전 관해 후 발병한 IgA 신병증 1예

임현민,김현정,박민석,주혜원,최원,김상현,박원도 인제대학교 2006 仁濟醫學 Vol.27 No.-

We report a rare case of primary glomerular disease with IgA nephropathy in a 43-year old man. 7-years ago, he was diagnosed with minimal change nephrotic syndrome. After treatment with steroid for 1-year, azotemia and proteinuria were improved. But, nephrotic range proteinuria was relapsed within 1 week after cessation of steroid. Renal biopsy revealed focal segmental glomerulosclerosis, and achived a complete remission with the use of steroids and cyclophosphamide. Then, he was followed up with normal renal function for 4-years. On admission, the patient showed generalized edema and marked proteinuria. In 3rd renal biopsy, mesangial proliferative glomerulonephritis with diffuse global sclerosis was observed. Electron microscopy showed electron-dense deposit on the mesangium with slight mesangial proliferation, and immunofluoroscence microscopy showed granular deposits of IgA and IgM. These features were consistent with IgA nephropathy, different from results of previous biopsies. The pathogenesis of IgA nephropathy occurred with primary FSGS is not clear, as well as treatment. Now, proteinuria is improving, steroid and cyclophosphamide are probably useful for the disease.

해안대수층 지하수흐름의 특성 : 실내 실험연구 LABORATORY EXPERIMENTS

박남식,김진후,나겐드라 쿠마,홍성훈,김현도 東亞大學校建設技術硏究所 2004 硏究論文集 Vol.28 No.1

Experiments were conducted using laboratory models to study salt water intrusion phenomena in coastal aquifers. Two models filled with sand were used. The smaller model could produce steady-state cross-sectional flow in a reasonably short time. The bigger model produced a more interesting three-dimensional flow field compare to the smaller one, but it also took much more time to reach steady states and posed difficulties in observing results. A cross-sectional model was used to investigate 'freshwater lens'phenomena. A few pumping scenarios were tested. Contamination of the well with excessive withdrawal was observed. The effectiveness of a scavenger well was studied. The bigger model was used to study the steady-state lateral intrusion problems. Various attempts were made to measure the interface position in the sand.

소각재에 함유된 중금속성분의 농도 분석

박현서,정진도 공주대학교 자원재활용 신소재 연구센터 2002 센터사업 성과집 Vol.- No.1

The disposal of municipal solid waste is a serious problem in Korea and throughout the world General diposal methods-incineration or dumping in landfills-creat more problems than they could be solved. Incineration generates toxic ashes and gase, and landfills will soon reach capacity and do not gurarantee the safe containment of harmful substances. Recently the fly ash has been classified as hazardous waste and diposal is no longer allowed unless it is treated by new law, the bottom ash also has become a very controversial issue due to their harmfulness. Sampling and analysis of ash at the three MSW incinerators was performed to determine if beneficial use could be made of this material. According to the results of analysis with HELOS, Atomic Absorption Spectrophotometry, and ICP-MS, bottom ashes included only 8.8% of PM-10 and Fly ashes, on the other hand, included approximately 50% which represented a very dangerous level. Among 17 heavy metals, tested Pb was detected to the extent harmful to human body, while the rest were discovered relatively to be lower level compared to Po.

저칼슘식이 생쥐 하악골에서 파골세포의 Tartrate저항성 산성인산분해효소 활성에 대한 세포화학적 연구

박은주,임도선,김현만,고재승 대한구강해부학회 1994 대한구강해부학회지 Vol.18 No.1

The present study was carried out to exanine the morphological changes and TRACP (Tartrate resistant acid phosphatase) activity in the resorption of mandibular bones of mouses resulted, established by low calcium diet. Mice were divided into two groups; one was the calcein group for fluorescent microscopy, the other was the non-calcein group for light and electron microscopy. After calcein injection, mice(ICR) were fed either a low calcium diet (0.01% Ca, 0.75% P) or control diet (0.1% Ca. 0.75% P). Non-calcein group were also fed a low calcium diet or control diet. Mice were sacrificed on 3, 7 and 14 days. For fluorescent microscopy study, fixed undecalcified alveolar bones were embedded in Epon 812, and ground sectioned to study the new bone formation after calcein injection. For the TRACP histochemical study, fixed decalcified alveolar bones were incubated in p-NPP (p-nitrophenyl phosphate) media. For the transmission electron microscopic study, incubated alveolar bone were post fixed in OsO_(4), embedded with Epon 812 for the study of TRACP localzation and activity. The observed results were as follows. 1. Low calcium diet induced bone resorption in buccal and lingual sides of alveolar bone, while the lingual side of alveolar bone was not resorbed in the control group. Bone resorption increased over the period of low calcium diet. 2. The alveolar bone proper of the lingual alveolar bone continued to deposit new bone of the periodontal side even after the low calcium diet. 3. After low calcium diet TRACP activity increased in the cytoplasm of osteoclast, extracellular ruffled border. TRACP activity was also found at the eroded bone matrix after bone resorption, and in the cytoplasm of detached osteoclast. In the immature osteoclast enzyme activity was confined in rER. No enzyme activity was found in the osteoblast.

후매립 단일앵커의 강도특성

박완신,황선경,윤현도 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2(구조계)

Many models for the design of post-installed steel anchors are presented in this paper. These approach are compared to each other, especially the well-known provisions of CEB method, ACI 349-90 and the CCD method. The use of these methods to predict the concrete failure load of fastenings in uncracked concrete under monotonic loading for important applications is compared. Variables included single anchors away from and close to the edge, embedment depth, concrete strength, tension loading, and shear loading. A data bank including Korean, European and American tests was evaluated. The comparison shows the CCD Method and CEB Method can accurately predict the concrete failure load of fastenings of the full range of investigated applications. On the other hand, depending on the application in question, the predictions of ACI 349-90 and VAC Method are sometimes unconservative and sometimes conservative.

Vibrio cholerae non-01/0139복막염 1예

박도심,이영진,김신무,조지현 대한임상미샐물학회 2000 Annals of clinical microbiology Vol.3 No.2

Irbesartan과 Lercanidipine의 병용요법이 고혈압 및 혈관재형성에 미치는 효과

이도형, 임태완, 조은지, 박현수, 정상혁, 한주희, 병창선 충남대학교 약학대학 의약품개발연구소 2017 藥學論文集 Vol.32 No.-

Hypertension is one of the major risk factor for cardiovascular disease and can lead to or make worse many complications, heart disease, atherosclerosis and diabetes. Thus, managing blood pressure effec tively using therapeutic drugs such as angiotensin II receptor blocker (ARB) and Ca2+ channel blocker (CCB) can be prevent other complications. Therefore, we investigated the synergistic effect of these two drugs, ir besartan and lercanidipine, for antihypertension, cardioprotection and antidiabetes. Irbesartan (28.74 mg/kg, 14.37 mg/kg) or lercanidipine (1.92 mg/kg, 0.96 mg/kg) alone or combination was administered to sponta-neously hypertensive rats (SHRs) and C57BL/6 mice. A two-week treatment of combination with irbesartan and lercanidipine significantly attenuated systolic blood pressure (SBP) and mean arterial pressure (MAP) compared with monotherapy. Futhermore. the combination therapy protected myocardial ischemia reperfusion injury more effectively than monotherapy. In vascular remodeling, combination therapy significantly diminished cuff -induced neointima formation and reduced serum -indllced vascular smooth muscle cells (VSMCs) pro-liferation compared with monotherapy. However, combination therapy had no significant synergistic effect of blood glucose regulation. Taken together, present study suggest that the combination therapy of irbesartan and lercanidipine may be more effective therapeutic strategy for the treatment of hypertension and related complications, myocardial infarction and arterial restenosis than monotherapy

중증 근무력증 52례에 대한 임상적 고찰

박건주,하정상,이준,도현철,박승권,서상덕,기병수,김진국 영남대학교 의과대학 1996 Yeungnam University Journal of Medicine Vol.13 No.1

1985년 8월부터 1996년 1월까지 중증근무력증으로 진단받은 환자 52례에 대한 임상적 고찰을 통하여 다음과 같은 결론을 얻었다. 1. 전체 환자 중 남자가 19례(35.8%), 여자가 33례(64.2%)이넜고 11세에서 20세 사이가 12례(23%)로 가장 높은 빈도를 보였다. 2. 환자의 초기증상으로는 안검하수, 복시 등의 안구증상이 37례(71.2%)로 가장 많았고 modified Osserman의 분류에 따라서도 가장 증상이 가볍고 약물치료에 잘 반응하는 1군이 36례(69.3%)로 가장 많았다. 3. 환자가 호소하는 증상의 비특이성과 회복과 재발을 거듭하는 질병의 특성으로 인해 발병이후 진단될 때까지의 시간은 비교적 오래 걸렸고 1년이상 경과하며 진단된 경우도 16례(30.8%)나 되었다. 4. 자가면역질환이 7.6%에서 동반되었는데 갑상선기능 항진증이 2례(3.8), 인슐린의존형 당뇨 2례(3.8%)였고 종격동 전산화 단층촬영소견에서 흉선의 비대가 의심되었던 환자는 6례(11.5%), 흉선종이 발견 되었던 경우는 3례였다. 5. 환자의 치료는 대부분 항콜린에스테라제나 부신피질호르몬을 병용하는 내과적 치료를 하였으며 약물의 치료에 반응이 미비하거나 악화되는 경우 혹은 종격동 전산화 단층촬영상에서 흉선의 이상 소견이 보인 경우에 2례(3.9%)에서는 흉선절제술이, 1례(1.9%)에서는 혈장여과요법이 추가 되었고 흉선절제술과 혈장여과요법이 같이 병합 치료된 경우도 3례(5.9%)있었다. 6. 전체 환자중 2명에서 자연치유의 경과를 보였으며 이들은 모두 1군이였다. 그리고 흉선절제술과 부신피질 호르몬 투여로 완치된 예가 1례있었다. The authors experienced 52 patients with myasthenia gravis who were diagnosed at the Department of Neurology, Yeungnam University Hospital from August 1985 to January 1996. The following results were obtained through diagnostic evaluation and treatment. 1. The ratio of male to female was 1:1.7 and the most prevalent age group was second decade. 2. The most common initial presentation symptom was ocular(71.2%) and the peak incidence group was stage I(69.3%) according to the modified Osserman's classification. 3. In 16 patients(30.8%), it took more than a year to diagnose due to symptoms which were relapsed and remitting. 4. Of 52 patients, 2 cases were associated with thyroid disease(3.8%) and 2 with insulin-dependent diabetes mellitus(3.8%). 5. All of those who received anticholinesterase and corticosteroid therapy were improved with the exception of 5 cases which were improved after thymectomy and/or plasmapheresis. 6. Spontaneous remission was occured in 2 cases(3.8%) of ocular myasthenia gravis. And 1 case of group II was cured through thymectomy and long-term corticosteroid therapy.