달리기 운동 프로그램이 시각장애인의 건강관련 체력에 미치는 영향

이명수,양점홍,홍순미,최재현,박원익,이창준 釜山大學校 附設 體育科學硏究所 2004 體育科學硏究所 論文集 Vol.20 No.-

The purpose of this study was to find out the effect of jogging(LSD ; Long Slow Distance) and walking training on health-related fitness of the blind.....

水泳이 肥滿 治療에 미치는 效果

이명수,이철원 公州大學校 스포츠科學硏究所 1997 스포츠科學硏究所論文集 Vol.- No.11

To examine that swimming effect the cure of obesity, ten obesity women had been educated by the program of swimming for the cure of obesity during 12weeks(96.6.3-8.24). And the results which is following nest sentence. 1. After the obesity management program, a variation of weight surely reduced. 2. After the obesity management program, a variation of subcutaneous fat sur ely reduced. 3. After the obesity management program, a variation of triglyceride in blood surely reduced. 4. After the obesity management program, a variation of cholesterol in blood surely reduced, and HDL in blood surely reduced.

흉통의 양상에 따라 분류한 불안정형 협심증 환자의 임상적 소견의 비교

김명수,김성구,정호석,온영근,신원용,김철현,최태명,현민수,권영주 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.1

Background and aims : The clinical syndrome unstable angina pectoris that encompasses a variety of symptoms and clincal presentations of transient episode of myocardial ischemia, was devided to several subgroups. Also, it has variable pathophysiologic factors to cause myocardial ischemia. According to clincal presentation, coronary angiographic finding and prognostic factor, the result of unstable angina pectoris is variable. In fact, there were a few data reported on the prognosis of wide spectrum of patients with unstable angina. However, the precise risk of subgroups according to classitication has not been established because it was difficult to compare between studies. We classified unstable angina pectoris by clinical nature of chest pain, and performed to establish and compare the clinical presentations, coronary angiographic findings, treatement and prognosis of patients with unstable angina within subgroups of classification. Methods : Retrospenctive data for 164 unstable angina pectoris patients admitted to the Internal Cardiology Division of Soon Chun Hyang University Hospital from May 1996 to July 1999 was analyzed. The patients were classified into one of the following categories: Class I, new onset of severe angina; Class II, acceleration of previous chronic stable angina; Class III, angina at rest. Clinical presentations, echocardiographic findings, coronary angiographic findings, treatment and prognosis were compared. Results : From the total 164 patients, the subjects of classes were as follows : Class I, 46 cases (28.1%); Class II, 74 cases (45.1%); Class III, 44 cases (26.8%). In view of age distribution, the 7th decade had the highest incidence, and then, 6th, 8th decades were followed. There was no baseline differences among the 3 classes with respect to gender, number of risk factors. Significantly, class II showed more severe findings in abnormal Q wave 15 cases (20.8%), total occclusive lesion 10 cases (20.8%) and three vessel coronary disease 11 cases (22.9%) than other classes. The change of ST segment was significantly apparent (p<0.02) among class I 28 cases (60.8%), class III 26 cases (59.0%), comparing with class II 30 cases (40.5%). Class III had the higher incidence of one vessel coronary artery disease than class I and III. The heparin treatment was performed in 99 cases (60.1%). The incidence of nonfatal myocardial infarction was much more in class I and III, each 4 cases (8.7%, 9.8%) than in class II 1 cases (1.4%). In-Hospital death was occurred in class I and II, each 1 case. Conclusion : The patients with the acclerated angina from chronic stable angina had more severe coronary artery disease than other classes, but they had better in-hospital prognosis.

퍼지추론규칙을 이용한 적응형 평가시스템

엄명용,정순영,이원규 한국컴퓨터교육학회 2003 컴퓨터교육학회 논문지 Vol.6 No.4

본 논문에서는 기존의 LCMS에서 사용되는 평가시스템에 퍼지 추론 규칙을 이용한 적응형 퍼지평가시스템(AFES : Adaptie Fuzzy Evaluation System)을 제안한다. AFES 는 학습자가 하나의 학습코스(learning course)에 들어가기 전에 퍼지진단평가(fuzzy diagnostic evealuation)를 통해 학습자에게 코스수준(course level)을 부여한다. 학습자는 코스수준에 따른 맞춤식 학습경로(learning path)로 학습을 종료한 후, 퍼지최종평가(fuzzy final evaluation)를 통해 최종성적(final grade)을 AFES 으로부터 부여 받는다. AFES, 의 가장 큰 특징은 최종성적의 점수 부여 규칙에 있는데, 만약 서로 다른 학습자가 동일한 문제 수에 대하여 같은 수의 정답을 냈더라도, AFES 는 125 가지 퍼지 추론 규칙(fuzzy reasoning rule)에 의거하여 탄력적으로 서로 다른 최종성적을 학습자에게 부여한다. We introduce an AFES(Adaptive Fuzzy Evaluation System) that applies an evaluation system used to existing LCMS(Learning Contents Management System) to a fuzzy reasoning rule. The AFES confers a course level on the learner through a fuzzy diagnostic evaluation before the learner enters a learning course. After the learner completes a learning course through the tailored learning path that is suitable for the learner’s level, the AFES confers a final grade on the learner by means of fuzzy final evaluation. The biggest characteristic of the AFES is a grade rule of the final grade. Although different learners get the same number of correct answers to the same number of questions, AFES flexibiv confers the different final grade on the learner by means of the number of 125’s fuzzy reasoning rules.

로자탄 대 포시노프릴의 고혈압 환자들에서 항고혈압 효과, 안전성 및 내약성의 비교

박대균,이명묵,채인호,이무용,이홍자,김효수,김철호,손대원,오병희,박영배,최윤식 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.1

뇌 신경교종에서의 증식능과 세포고사

김영철,박명수,양정원 조선대학교 2001 The Medical Journal of Chosun University Vol.26 No.1

Background and Objectives : Proliferating cell nuclear antigen (PCNA) correlated with the rates of cellular proliferation and DNA synthesis. It is 36-kD nuclear acidic protein, and present throughout the cell cycle. Apoptosis also correlates with tumor development. The purpose of this study is the investigate of the relationshipal PCNA and apoptotic rates in gliomas. Materials and Methods : This study analyzed 50 paraffin-embedded glioma, including 15 cases of low grade, 20 cases of high grade, and 15 cases of maligant glioma (glioblastoma multiforme), for the status of proliferating index and apoptotic rates. The evaluation of immunostaining result was based on the percentage of positive neoplastic cells. Results : Average positive cell rates of PCNA were 14.3%, 45.2% and 62.0% in low grade glioma, high grade glioma and glioblastoma multiforme, respectively. Apoptotic rates were 52.3%, 41.0% and 25.2% in low grade glioma, high grade glioma and glioblastoma multiforme, respectively. Conclusion : This results suggest that PCNA positivity was correlated with histologic grade of glial tumors. And high grade glioma and glioblastoma multiforme showed higher positive cell rate rather than low grade glioma. Apoptotic rates were higher in low grade glioma than high grade or malignant glioma. So, the PCNA and the apoptosis rates is great useful parameter for a patient’ s prognosis.

급성 백혈병 환자에서 발생한 감염 양상의 분석(1986~1992)

박선양,오명돈,김양수,백경란,김병국,최강원,김성민 대한감염학회 1993 감염 Vol.25 No.3

Infection is a major complication and potentially life-threatening in patients with acute leukemia. The patients require prompt broad-spectrum antibiotics therapy when fever develops. One of the keys to successful patient management is the recognition of institutional trends of the spectrum of infections and infecting microorganisms. So we evaluated 138 patients with acute leukemia and blastic crisis of chronic myelogenous leukemia admitted to Seoul National University Hospital from July 1986 to June 1992. The results are following: 1) Total number of febrile episodes was 224 and 60% of them occurred after chemotherapy. 2) Microbiologically-defined infection, clinically-defined infection, and unexplained fever accounted for 28%, 45%, 27% of the febrile episodes respectively. 3) Fifty-eight percent of microbiologically-defined infections were caused by gram-negative bactria, and 36% were gram-positive bacteria. There was a tendency to a greater proportion of gram (+) organisms than that of the last study (p>0.1). Escherichia coli was the most common organism, and coagulase-negative staphylococci, Pseudomonas aeruginosa, Klebsiella pneumoniae were common in decreasing order. 4) Pneumonia was the most common type of infection, followed by skin and soft tissue infection, perianal infection, gingivitis and primary septicemia. 5) Seventy-two percent of total infections improved with therapy and this success rate was higher than that of the last study(p<0.001).

1~2기 본태성 고혈압 환자들에서 Imidapril 대 Enalapril의 항고혈압 효과를 평가하기 위한 무작위, 이중맹검 임상시험

최영진,손대원,김용진,이홍자,채인호,김효수,김철호,오병희,이명묵,박영배,채윤식,이영우 대한순환기학회 1999 Korean Circulation Journal Vol.29 No.11

ANATOMICAL EXPANDER와 IMPLANT를 이용한 유방 재건의 경험

고법민,박원진,김재중,하범준,이재승,신명수 大韓成形外科學會 1999 Archives of Plastic Surgery Vol.26 No.3

The use of a tissue expander and implant is the simplest option for breast reconstruction after mastectomy. Use of a round dome-shaped prosthesis and the commonly used one-stage technique with a Becker type prosthesis, however, often produces an undesirable upper pole fullness. To overcome this and to achieve improved aesthetic results, we started using an anatomically-shaped expander and implant, as described by Maxwell, as a two-stage breast reconstruction. We reviewed the results of our 21 reconstructed breasts in 22 patients who were deemed suitable for reconstruction using this technique since January 1995. The most commonly used expander was 350cc (range 350-550cc) and an average of 4.2 inflations were required before replacing the expander with a permanent implant. All the expanders were placed in submuscular pockets and implant volume. The longest follow-up was 36 months. Few complications developed and most patients were satisfied with the results. We found that the anatomically-shaped expander and implant produced better aesthetic results compared to a done-shaped prosthesis.

임산부에서 발생한 폐크립토콕쿠스증을 동반한 크립토콕쿠스 수막뇌염 1예

박경화,송진수,최평균,방지환,조재현,박완범,김홍빈,김남중,오명돈,최강원 대한감염학회 2006 감염과 화학요법 Vol.38 No.4

Cryptoccus necoformans는 면역기능이 저하된 환자에서 기회 감염을 일으키는 진균이나 정상인에서도 드물게 질병을 일으킨다. 그러나 임산부에서 폐크립토콕쿠스증을 동반한 크립토콕쿠스 수막염의 보고는 아주 드물다. 저자들은 분만 후에도 악화되는 두통과 의식저하로 내원한 임신 37주의 임산부에서 뇌척수액과 폐조직검사를 통해 폐크립토콕쿠스증을 동반한 크립토콕쿠스 수막뇌염을 진단하고 항진균제를 사용하여 치료하였다. 본 증례처럼 명백한 기저질환이 없는 임산부에서도 크립토콕쿠스 수막염은 발생할 수 있으므로 의심이 되면 뇌척수액검사를 포함한 진단적 검사를 시행하고 적절한 치료를 시작해야한다. 그리고 임산부에서 크립토콕쿠스증이 발생한 경우의 치료에 대하여 문헌 고찰과 함께 보고하는 바이다. Cryptoccocosis occurs more frequently in immunocompromised hosts such as patients with AIDS, lymphoma, leukemia and other debilitating diseases. Pulmonary cryptococcosis can occur in the absence of any recognized immunodeficiency and cryptococcal meningitis can occur rarely during pregnancy. Although it is extremely rare, we encounter the reports of case of cryptococcal pneumonia and combined cryptococcal meningitis during pregnancy. We present here that 36-year-old pregnant woman, who was previously healthy, with cryptococcal meningoencephalitis and cryptococcal pneumonia was treated with amphotericin B and flucytosine. The maternal outcome was favorable, and there is no evidence of congenital infection in the newborn.