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      • KCI등재후보

        GIS를 이용한 산불발생위험지역 구분

        이시영,안상현,원명수,이명보,임태규,신영철 한국지리정보학회 2004 한국지리정보학회지 Vol.7 No.2

        산불로 인한 재해를 미연에 방지하고 피해를 저감하기 위해서는 산불발생위험지역을 사전에 파악하여 예방대책을 세울 필요가 있다. 따라서 본 연구에서는 산불발생인자에 따른 산불발생위험지역을 구분하고자 겸상북도 의성군에서 발생한 산불피해지역에 대하여 임상, 지형 등에 대하여 조사하였다. 조사된 요인들 간 독립성 유무를 상관분석을 이용하여 산불발생과 관련 있는 7개의 주제도를 선정하였으며, 선정된 주제도를 조건부확률과 지리정보시스템을 이용하여 산불발생확률을 계산하였다. 계산된 산불발생확률을 20개 등급으로 지수화하여 산불발생위험지역을 구분하였다. In order to decrease the area damaged by forest fires and to prevent the occurrence of forest fires, we are making an effort to improve prevention measures for forest fires. The objective of this study is to classify hazard regions where forest fires occur based on the factors that contribute to the occurrence of forest fires. Forest fire sites in the Uiseong-gun, Gyeongsangbuk-do were surveyed according to the factors of forest type and topographic characteristics where the forest fires occurred. We used a correlation analysis to determine the forest fire occurrence factors and a conditional probability analysis and GIS to determine a forest fire danger index. The resulting forest fire danger index was used in the classification of forest fire occurrence risk regions.

      • KCI등재후보

        퍼지추론규칙을 이용한 적응형 평가시스템

        엄명용,정순영,이원규 한국컴퓨터교육학회 2003 컴퓨터교육학회 논문지 Vol.6 No.4

        본 논문에서는 기존의 LCMS에서 사용되는 평가시스템에 퍼지 추론 규칙을 이용한 적응형 퍼지평가시스템(AFES : Adaptie Fuzzy Evaluation System)을 제안한다. AFES 는 학습자가 하나의 학습코스(learning course)에 들어가기 전에 퍼지진단평가(fuzzy diagnostic evealuation)를 통해 학습자에게 코스수준(course level)을 부여한다. 학습자는 코스수준에 따른 맞춤식 학습경로(learning path)로 학습을 종료한 후, 퍼지최종평가(fuzzy final evaluation)를 통해 최종성적(final grade)을 AFES 으로부터 부여 받는다. AFES, 의 가장 큰 특징은 최종성적의 점수 부여 규칙에 있는데, 만약 서로 다른 학습자가 동일한 문제 수에 대하여 같은 수의 정답을 냈더라도, AFES 는 125 가지 퍼지 추론 규칙(fuzzy reasoning rule)에 의거하여 탄력적으로 서로 다른 최종성적을 학습자에게 부여한다. We introduce an AFES(Adaptive Fuzzy Evaluation System) that applies an evaluation system used to existing LCMS(Learning Contents Management System) to a fuzzy reasoning rule. The AFES confers a course level on the learner through a fuzzy diagnostic evaluation before the learner enters a learning course. After the learner completes a learning course through the tailored learning path that is suitable for the learner’s level, the AFES confers a final grade on the learner by means of fuzzy final evaluation. The biggest characteristic of the AFES is a grade rule of the final grade. Although different learners get the same number of correct answers to the same number of questions, AFES flexibiv confers the different final grade on the learner by means of the number of 125’s fuzzy reasoning rules.

      • 정신분열병 증상을 동반한 진행성 핵상 마비 1례

        박종익,조영래,홍진표,이민규,한오수,이명종 대한신경정신의학회 2001 신경정신의학 Vol.40 No.1

        저자들은 환청과 망상을 주소로 정신과를 방문한 진행성 핵상 마비 환자를 진단하고 치료하였다. 진행성 핵상 마비는 보행 장해, 치매, 수직성 안구 운동의 장해가 특징적인 증상이며, 아직까지 특별한 치료법은 알려져 있지 않다. 정신과적 증상으로는 인지기능의 장해, 정동 및 행동의 변화, 수면 장해, 정신병적 증상 등이 있으며 정신분열병과 비슷한 증상을 보이는 경우는 극히 드물다고 한다. 본 증례에서는 파킨슨 증상과 정신병적 증상이 비슷한 시기에 발현된 진행성 핵상 마비의 예를 보고하면서 진단적 중요성을 강조하고자 한다. We have experienced a rare case of progressive supranuclear palsy with hallucination and delusion. The common manifestations of progressive supranuclear palsy are gait disturbance, mental change and sign of vertical ophthamoplegia but no efficacious therapy has been known. Neuropsychiatric symptom clusters include cognitive impairment, affective and behavioral changes, sleep disturbance, and psychotic symptoms. Though schizophrenia-like psychosis has been reported but this is certainly rare. Addressing a case of progressive supranuclear palsy, in whom parkisonian symptoms appeared with concurrent psychotic symptoms, we emphasize accurate diagnosis.

      • Plenary Session 2 : PS-2-1 ; Outcomes of hepatitis B virus recurrence after liver transplantation: a multicenter analysis in Korea

        ( Hee Yeon Kim ),( Jong Young Choi ),( Dong Goo Kim ),( Myoung Soo Kim ),( Soon Il Kim ),( Shin Hwang ),( Sung Gyu Lee ),( Kwang Woong Lee ),( Kyung Suk Suh ),( Young Seok Han ),( Dong Lak Choi ),( Se 대한간학회 2012 춘·추계 학술대회 (KASL) Vol.2012 No.-

        Background: The outcome of hepatitis B virus (HBV) infection after liver transplantation (LT) was improved by hepatitis B immunoglobulin (HBIG) and nucles(t)ide analogue (NUA). However, HBV recurrence after LT is critical because the recurrence is occasionally accompanied by a progressive destruction of graft and poor survival. The aims of this study were to investigate the significance HBV recurrence and identity factors associated with HBV recurrence. Methods: From October 1999 to February 2011, a total of 2684 consecutive LT recipients who underwent HBV-associated LT were retrospectively enrolled from 7 transplantation centers in Korea. Results: Prophylaxis regimens were HBIG monotherapy (67.7%) or a combination of HBIG with NUA (22.3%). The recurrence rate of HBV was 6.1% (164 recipients) during mean follow-up duration of 10.9 years. The median time from transplantation to recurrence was 2.1 years (0.1-7.9 years). Of the 1,071 patients with hepatocellular carcinoma (HCC) prior to LT, 155 patients (14.5%) had HCC recurrence after transplantation, and 48 patients (31.0%) had HBV recurrence. Of the 48 patients with recurrence of both HBV and HCC, 25 patients (52.1%) experienced HBV recurrence after HCC recurrence. In the multivariate analysis, pretransplant HCC, pretransplant HBV DNA above 5.5 log copies/mL was independent clinical factors influencing HBV recurrence after LT. The mortality rate among the recipients with HBV recurrence was 34.1% (56 recipients). Mean overall survival was 6.4 years in the HBV-recurrence group and 9.9 years in the HBV-nonrecurrence group (p<0.001). HBV recurrence was not an independent prognostic factor for overall survival. HCC recurrence was the most important factor for overall survival. Conclusions: The overall outcome of LT in HBV-related liver disease was excellent with the current prophylaxis regimen Choon Hyuck David Kwon,8 Suk-Koo Lee8 Pretransplant HBV DNA and HCC were important factors for HBV recurrence. HBV recurrence after LT did not significantly influence on the overall survival without combining of HCC recurrence.

      • Effect of Porous Graphite for High Quality SiC Crystal Growth by PVT Method

        Lee, Hee Jun,Lee, Hee Tae,Shin, Hee Won,Park, Mi Seon,Jang, Yeon Suk,Lee, Won Jae,Yeo, Im Gyu,Eun, Tai Hee,Kim, Jang Yul,Chun, Myoung Chul,Lee, Si Hyun,Kim, Jung Gon Trans Tech Publications, Ltd. 2015 Materials science forum Vol.821 No.-

        <P>The effect of the porous graphite plate above the source material on properties of silicon carbide (SiC) crystals grown by Physical Vapor Transport method has been investigated. The porous graphite plate was inserted on source powder to produce a more C-rich for the polytype stability of 4H-SiC crystal and a uniform radial temperature gradient. The dendrite structure obtained from SiC source powder in the crucible with porous graphite plate was more densely formed than that in the conventional crucible. The crystal quality of 4H-SiC single crystals grown in porous graphite inserted crucible was revealed to be better than that of crystal grown SiC crystals in the conventional crucible.</P>

      • Functional Architecture for NGN-Based Personalized IPTV Services

        Gyu Myoung Lee,Chae Sub Lee,Woo Seop Rhee,Jun Kyun Choi IEEE 2009 IEEE transactions on broadcasting Vol.55 No.2

        <P>IPTV is one of the most highly visible services to emerge as part of the development of next generation network (NGN). IPTV services over manageable broadband link from a provider will be one of the ultimate goals of the broadband revolution using NGN. In this paper, we analyze IPTV architecture developed by ITU-T and provide functional architecture for NGN-based IPTV services according to functional mapping between IPTV and NGN. For this, we provide the detailed functional architecture and relevant operations with other functional blocks and present the harmonized architecture between IPTV and NGN for NGN-based IPTV services with the alignment with existing NGN architecture. As challenging architectural issues, we also introduce personalized IPTV services based on Web-based open platform in NGN environment and illustrate functional architecture and service examples for Web-based personalized IPTV services.</P>

      • KCI등재

        Hepatocyte-specific Prominin-1 protects against liver injury-induced fibrosis by stabilizing SMAD7

        Lee Hyun,Yu Dong-Min,Bahn Myeong-Suk,Kwon Young-Jae,Um Min Jee,Yoon Seo Yeon,Kim Ki-Tae,Lee Myoung-Woo,Jo Sung-Je,Lee Sungsoo,Koo Seung-Hoi,Jung Ki Hoon,Lee Jae-Seon,Ko Young-Gyu 생화학분자생물학회 2022 Experimental and molecular medicine Vol.54 No.-

        Prominin-1 (PROM1), also known as CD133, is expressed in hepatic progenitor cells (HPCs) and cholangiocytes of the fibrotic liver. In this study, we show that PROM1 is upregulated in the plasma membrane of fibrotic hepatocytes. Hepatocellular expression of PROM1 was also demonstrated in mice (Prom1CreER; R26TdTom) in which cells expressed TdTom under control of the Prom1 promoter. To understand the role of hepatocellular PROM1 in liver fibrosis, global and liver-specific Prom1-deficient mice were analyzed after bile duct ligation (BDL). BDL-induced liver fibrosis was aggravated with increased phosphorylation of SMAD2/3 and decreased levels of SMAD7 by global or liver-specific Prom1 deficiency but not by cholangiocyte-specific Prom1 deficiency. Indeed, PROM1 prevented SMURF2-induced SMAD7 ubiquitination and degradation by interfering with the molecular association of SMAD7 with SMURF2. We also demonstrated that hepatocyte-specific overexpression of SMAD7 ameliorated BDL-induced liver fibrosis in liver-specific Prom1-deficient mice. Thus, we conclude that PROM1 is necessary for the negative regulation of TGFβ signaling during liver fibrosis.

      • KCI등재

        Genetic Diversity and Population Structure of a Korean Rice Germplasm Based on DNA Profiles

        Lee, Kyung Jun,Lee, Jung-Ro,Shin, Myoung-Jae,Cho, Gyu-Taek,Ma, Kyung-Ho,Lee, Gi-An,Chung, Jong-Wook The Korean Society of Crop Science 2018 한국작물학회지 Vol.63 No.1

        Information on the patterns of genetic diversity and population structure is essential for the rational use and efficient management of germplasms; accurate information aids in monitoring germplasms, and can also be used to predict potential genetic gains. In this study, we assessed genetic diversity, focusing on Korean rice accessions for theand their sustainable conserved diversity. Using DNA profiling with 12 simple sequence repeat (SSR) markers, we detected a total of 333 alleles among 2,016 accessions. The number of alleles ranged from 21 to 53, with an average of 27.8. Average polymorphism information content was 0.797, with the lowest being 0.667 and the highest 0.940. CA cluster analysis and the model-based population structure revealed two main groups that could be subdivided into five subgroups. Analysis of the molecular variance study based on the SSR profile data showed 5% variance among the profiles, whereas we recorded 93% variance among individuals and 2% variance within individuals. Specifically, the utilized diversity for of the breeding program is restricted in that cultivars were located in limited clades. These results revealed that preserving the diversity of Korean landraces could be useful sources for breeding new rice cultivars, and cwould be the basis for the sustainable conservation and utilization of a Korean rice germplasm.

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