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Molecular Cloning and Expression of Inositol 1,4,5 - Triphosphate 3 Kinase
Moon, Kyung Ho,Kim, Jae Won,Rhee, Sue Goo,KIM, HA KUN,Lee, Sang Yeol,Choi, Kwan Yong,Chung, Hong Keun,Sin, Sang Soo 한국유전학회 1990 Genes & Genomics Vol.12 No.4
Department of Life Science, Pohang Institute of Science and Technology, Pohang, Korea, *^Department of Biochemistry, Kyongsang National University, Chinju, Korea, (**)^Department of Biochemistry, Kyongsung University, Pusan, Korea, (++)^Department of Biochemistry, College of Medicine, Seoul National University, Seoul, Korea, +^Laboratory of Biochemistry, NHLBI, N.I.H., Bethesda, MD 20892, U.S.A.
A Study on How to Improve Magnesium Anodizing Process with High Biocompatibility
Sang-jun Kwon,Jin-young Hur,Chang-Myeon Lee,Kwan-seop Jang,Sung-mo Moon,Hong-kee Lee 한국표면공학회 2015 한국표면공학회지 Vol.48 No.5
Anodization of die-casted AZ91D magnesium alloy was carried out using silicate based electrolyte solution instead of fluoride based solution to improve biocompatibility of oxidized layers. The anodic layer obtained from silicate based solution has smaller size of pore and smoother surface, resulting in lower corrosion rate in simulate body solution (SBF). Effect of enhanced structural and chemical properties in oxidized layer on biocompatibility was carefully considered.
Clinical outcome of high-dose-rate interstitial brachytherapy in patients with oral cavity cancer
Sung Uk Lee,MD,Kwan Ho Cho,MD,Sung Ho Moon,MD,Sung Weon Choi,MD,Sung Uk Lee,MD,Kwan Ho Cho,MD,Sung Ho Moon,MD,Sung Weon Choi,MD 대한방사선종양학회 2014 Radiation Oncology Journal Vol.32 No.4
Purpose: To evaluate the clinical outcome of high-dose-rate (HDR) interstitial brachytherapy (IBT) in patients with oral cavity cancer. Materials and Methods: Sixteen patients with oral cavity cancer treated with HDR remote-control afterloading brachytherapy using 192Ir between 2001 and 2013 were analyzed retrospectively. Brachytherapy was administered in 11 patients as the primary treatment and in five patients as salvage treatment for recurrence after the initial surgery. In 12 patients, external beam radiotherapy (50–55 Gy/25 fractions) was combined with IBT of 21 Gy/7 fractions. In addition, IBT was administered as the sole treatment in three patients with a total dose of 50 Gy/10 fractions and as postoperative adjuvant treatment in one patient with a total of 35 Gy/7 fractions. Results: The 5-year overall survival of the entire group was 70%. The actuarial local control rate after 3 years was 84%. All five recurrent cases after initial surgery were successfully salvaged using IBT ± external beam radiotherapy. Two patients developed local recurrence at 3 and 5 months, respectively, after IBT. The acute complications were acceptable (≤grade 2). Three patients developed major late complications, such as radio-osteonecrosis, in which one patient was treated by conservative therapy and two required surgical intervention. Conclusion: HDR IBT for oral cavity cancer was effective and acceptable in diverse clinical settings, such as in the cases of primary or salvage treatment.