Effects of pregabalin and gabapentin on postoperative pain and opioid consumption after laparoscopic cholecystectomy

Mohammad Eidy,Mohammad Reza Fazel,Hossein Abdolrahimzadeh,Ali Reza Moravveji,Ebrahim Kochaki,Mahdi Mohammadzadeh 대한마취통증의학회 2017 Korean Journal of Anesthesiology Vol.70 No.4

Background: Gabapentin and pregabalin are antiepileptic drugs that are also used for chronic pain treatment. This study evaluated the effects of pregabalin and gabapentin on postoperative pain in patients undergoing laparoscopic cholecystectomy. Methods: A total of 108 candidates for elective laparoscopic cholecystectomy were randomly assigned to gabapentin (n = 36), pregabalin (n = 36), and placebo (n = 36) groups. Patients received 800 mg of gabapentin or 150 mg of pregabalin orally one hour before surgery. Postoperative analgesia was administered by pethidine via patient-controlled analgesia. The amount of opioid consumed, number of nausea events, vomiting, and pain scores at 2, 6, 12, and 24 hours after surgery were recorded. Results: The gabapentin and pregabalin groups had significantly lower pain intensity than the placebo group, and pain intensity in the pregabalin group decreased more compared to the gabapentin group. The mean amount of pethidine consumption in the placebo group was significantly higher than in the gabapentin and pregabalin groups. Conclusions: A single dose of gabapentin or pregabalin decreased postoperative pain and nausea, as well as vomiting and opioid consumption after laparoscopic cholecystectomy. Moreover, the findings revealed that pregabalin was superior to gabapentin for reducing postoperative pain.

One-dimensional nonlinear vibration analysis and coupled thermoelasticity based on Green-Naghdi model

Mohammad Hosein Nejabat Meimandi,Ali Reza Fotuhi,Mohammad Reza Fazel 대한기계학회 2019 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.33 No.2

The present article reports on a study on nonlinear coupled thermoelasticity based on Green-Naghdi type III model in one-dimensional form. Unlike other research in which temperature change is low and the strain relations are linear, in the present study the nonlinear finite strain assumption is governed. Two coupled nonlinear partial differential equations, namely; energy and linear momentum are established. The basic equations are formulated in material coordinates and then transformed into dimensionless form. The homotopy analysis method is used to analyze the one-dimensional structure. Two different cases are studied. The thermo-mechanical wave propagation with reflection from the boundary, and the influence of the damping parameter –presented in Green-Naghdi type III model– on temperature. The linear and nonlinear equations are compared. It should be noted that the nonlinear finite strain theory governs better when the loading temperature is high.

Sub-word Based Offline Handwritten Farsi Word Recognition Using Recurrent Neural Network

Mohammad Fazel Younessy Ghadikolaie,Ehsanolah Kabir,Farbod Razzazi 한국전자통신연구원 2016 ETRI Journal Vol.38 No.4

In this paper, we present a segmentation-based method for offline Farsi handwritten word recognition. Although most segmentation-based systems suffer from segmentation errors within the first stages of recognition, using the inherent features of the Farsi writing script, we have segmented the words into sub-words. Instead of using a single complex classifier with many (N) output classes, we have created N simple recurrent neural network classifiers, each having only true/false outputs with the ability to recognize sub-words. Through the extraction of the number of sub-words in each word, and labeling the position of each sub-word (beginning/middle/ end), many of the sub-word classifiers can be pruned, and a few remaining sub-word classifiers can be evaluated during the sub-word recognition stage. The candidate sub-words are then joined together and the closest word from the lexicon is chosen. The proposed method was evaluated using the Iranshahr database, which consists of 17,000 samples of Iranian handwritten city names. The results show the high recognition accuracy of the proposed method.

Combined Use of Sewage Sludge Ash and Silica Fume in Concrete

Fazel Azarhomayun,Mohammad Haji,Mahdi Kioumarsi,Ali Kheyroddin 한국콘크리트학회 2023 International Journal of Concrete Structures and M Vol.17 No.5

The lack of adequate space for sewage sludge disposal has become a significant challenge in many countries. Landfilling and using sewage sludge as fertilizer in agricultural lands are the main methods for disposal. However, these methods can result in soil and groundwater contamination as well as heavy metal and microbial pollution in soil. An alternative disposal method is using sewage sludge ash (SSA) in concrete production. If the sludge ash is reactive, it can replace a portion of cement in concrete; otherwise, it can be used as a filler. In the present study, X-ray fluorescence (XRF) experiments were conducted to determine the elemental composition of sewage sludge. Then, the sewage sludge was incinerated, and XRF and X-ray diffraction (XRD) tests were performed on the resulting sewage sludge ash. The ash was utilized in different proportions in the mortar and concrete specimens, and compressive strength tests were conducted on the resulting specimens. The results indicate that using 20% SSA instead of cement resulted in a 25% reduction in compressive strength in concrete specimens. However, the combination of 10% silica fume and 10% SSA was the optimal combination to compensate for the reduction in compressive strength caused using SSA.

Effects of Etymological Elaboration on the EFL Learners` Comprehension and Retention of Idioms

( Mohammad Sadegh Bagheri ),( Ismaeil Fazel ) 범태평양 응용언어학회 2010 Journal of Pan-Pacific Association of Applied Ling Vol.14 No.1

In recent years, idioms have received overwhelming attention in language pedagogy. Experts in the field have sought ways to optimize learning and teaching of these prefabricated language chunks. It is now maintained that the meaning of idioms which was once deemed as arbitrary is somehow ``motivated`` by their literal, original usage. Referring to the etymology of idioms in order to understand their idiomatic meaning is called`` etymological elaboration``. This study sought to explore the effect of this technique on learners` comprehension as well as retention of idioms. It appears that this effect can be explained by Dual Coding Theory where the etymological association calls up a mental image of a concrete scene which can be stored alongside the verbal form in memory. In this experiment 50 Iranian advanced students studying English at Bahar Language Institute, Shiraz were divided into two homogeneous groups of experimental and control. The test of the former group comprised a matching task pertaining to the origin of idioms, a multiple - choice task concerning the idiomatic meaning of idioms, a multiple-choice task regarding the idiomatic meaning of idioms and a gap-filling task in which subjects were supposed to provide the missing keyword for each idiom. The control group just had a test including multiple choice as well as gap filling tasks. The matching task was utilized as a treatment to demonstrate the effect of knowing the origin of idioms on the participants` performance on the other tasks. The participants` mean scores were calculated , in both identify-the-meaning` and ``gap-filling`` tasks, the mean score of participants provided with the etymological elaboration was more than those who did not receive this treatment, which indicated that etymological elaboration enhanced the learners comprehension and retention of idioms effectively.

Ginsenoside Rd and ischemic stroke; a short review of literatures

Seyed Fazel Nabavi,Antoni Sureda,Solomon Habtemariam,Seyed Mohammad Nabavi 고려인삼학회 2015 Journal of Ginseng Research Vol.39 No.4

Panax ginseng is a well-known economic medical plant that is widely used in Chinese traditional medicine. This species contains a unique class of natural productsdginsenosides. Recent clinical and experimental studies have presented numerous lines of evidence on the promising role of ginsenosides on different diseases including neurodegenerative diseases, cardiovascular diseases, and certain types of cancer. Nowadays, most of the attention has focused on ginsenoside Rd as a neuroprotective agent to attenuate ischemic stroke damages. Some of the evidence showed that ginsenoside Rd ameliorates ischemic stroke-induced damages through the suppression of oxidative stress and inflammation. Ginsenoside Rd can prolong neural cells’ survival through the upregulation of the endogenous antioxidant system, phosphoinositide-3-kinase/AKT and extracellular signal-regulated protein kinase 1/2 pathways, preservation of mitochondrial membrane potential, suppression of the nuclear factor-kappa B, transient receptor potential melastatin, acid sensing ion channels 1a, poly(ADP-ribose) polymerase-1, protein tyrosine kinase activation, as well as reduction of cytochrome c-releasing and apoptosis-inducing factor. In the current work, we review the available reports on the promising role of ginsenoside Rd on ischemic stroke. We also discuss its chemistry, source, and the molecular mechanism underlying this effect.

Epidemiology of Female Reproductive Cancers in Iran: Results of the Gholestan Population-Based Cancer Registry

Taheri, NegarSadat,Fazel, Abdolreza,Mahmoodzadeh, Habibollah,Omranpour, Ramesh,Roshandel, Gholamreza,Gharahjeh, Saeedeh,Sedaghat, Seyed Mehdi,Poorabbasi, Mohammad,Moghaddami, Abbas,Semnani, Shahryar Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.20

Background: Malignancies of the female reproductive tract are estimated to be the third most common group of cancers in women. Objectives: We here aimed to present their epidemiological features in Golestan province located in Northeast of Iran. Materials and Methods: Data on primary female reproductive cancers diagnosed between 2004-2010 were obtained from Golestan Population-based Cancer Registry (GPCR). CanReg-4 and SPSS software were used for data entry and analysis. Age standardized incidence rates (ASR) (per 100,000 person-years) were calculated using the world standard population. Poisson regression analysis was used to compare incidence rates. P-values of less than 0.05 were considered as significant. Results: A total of 6,064 cancer cases were registered in Golestan females in the GPCR during 2004-2010, of which 652 cases (11%) were female reproductive cancers. Cancers of the ovary (ASR=6.03) and cervix (ASR=4.97) were the most common. We found significant higher rates in females living in cities than in villages. Our results showed a rapid increase in age specific incidence rates of female reproductive cancers at the age of 30 years. Conclusions: We found significant higher rates of female reproductive cancers among residents of cities than villages. Differences in the prevalence of risk factors including reproductive behavior between the two populations may partly explain such diversity. Our results also showed a rapid increase in incidence rates of these cancers in young age females. Further studies are warranted to determine risk factors of female reproductive cancers in our population.

The Effect of Microencapsulation of Phenolic Compounds from Lemon Waste by Persian and Basil Seed Gums on the Chemical and Microbiological Properties of Mayonnaise

Shima Shaygannia,Mohammad Reza Eshaghi,Mohammad Fazel,Mahnaz Hashemiravan 한국식품영양과학회 2021 Preventive Nutrition and Food Science Vol.26 No.1

Natural preservatives with high level of phenolic compounds, antioxidants and antimicrobial activities are used in mayonnaise to improve quality and safety due to their potential health benefits. Application of these compounds in production processes highlights many difficulties due to instability of their physical and chemical properties. Microencapsulation is used to address these restrictions. In this study, phenolic compounds from lemon waste were encapsulated with Persian gum (PG) and basil seed gum (BSG) as coating materials at different ratios (0:1, 1:0, and 1:1) at 15% (w/w) total biopolymer. We confirmed microencapsulation by scanning electron microscopy, and evaluate phenolic content, antioxidant activity, encapsulation efficiency, morphology, water solubility indexes, and water absorption indexes. Sample mayonnaise was prepared using microencapsulated polyphenols from lemon waste and extract (1,000 ppm of concentration), and control samples without extracts or microcapsules. All samples were subjected to chemical (measuring the peroxide, thiobarbituric acid, acidity, and color) and microbial (total count of microorganisms and Escherichia coli) analysis during 30 days of storage. BSG samples exhibited the highest antioxidant activity (61.19%) and encapsulation efficiency (70.72%), and PG/BSG microcapsules had the highest capability to prevent oxidative deterioration during storage. Addition of microcapsules led to increases in parameter b* and decreases in parameters a* and L*. In general, PG/BSG microcapsules were considered optimal samples for production of mayonnaise, since they prevented mayonnaise deterioration and exhibited antioxidant and antimicrobial properties.

Ginsenoside Rd and ischemic stroke; a short review of literatures

Nabavi, Seyed Fazel,Sureda, Antoni,Habtemariam, Solomon,Nabavi, Seyed Mohammad The Korean Society of Ginseng 2015 Journal of Ginseng Research Vol.39 No.4

Panax ginseng is a well-known economic medical plant that is widely used in Chinese traditional medicine. This species contains a unique class of natural products-ginsenosides. Recent clinical and experimental studies have presented numerous lines of evidence on the promising role of ginsenosides on different diseases including neurodegenerative diseases, cardiovascular diseases, and certain types of cancer. Nowadays, most of the attention has focused on ginsenoside Rd as a neuroprotective agent to attenuate ischemic stroke damages. Some of the evidence showed that ginsenoside Rd ameliorates ischemic stroke-induced damages through the suppression of oxidative stress and inflammation. Ginsenoside Rd can prolong neural cells' survival through the upregulation of the endogenous antioxidant system, phosphoinositide-3-kinase/AKT and extracellular signal-regulated protein kinase 1/2 pathways, preservation of mitochondrial membrane potential, suppression of the nuclear factor-kappa B, transient receptor potential melastatin, acid sensing ion channels 1a, poly(ADP-ribose) polymerase-1, protein tyrosine kinase activation, as well as reduction of cytochrome c-releasing and apoptosis-inducing factor. In the current work, we review the available reports on the promising role of ginsenoside Rd on ischemic stroke. We also discuss its chemistry, source, and the molecular mechanism underlying this effect.

A Comparison of the Compression-Recovery Behavior of Conventional and Double-Base Persian Rugs: Compression Behavior

Milad Sadeghi-Sadeghabad,Aliasghar Alamdar-Yazdi,Mohammad R. Fazel,Hasan Mashroteh 한국섬유공학회 2020 Fibers and polymers Vol.21 No.6

One of the most important behaviors of a rug is its compression-recovery effect. This paper compares thecompression properties of a conventional and a new Persian rug. In the new rug, some free spaces are created in the base partwithin the warp sheets. To do the comparison experiments, five rug samples were produced: A conventional Persian rug asthe comparison criterion plus four new types of rugs named Double-base Persian (DBP) rugs. At first, a theoretical analysisof the compression process in both conventional and new rugs is presented for further comparisons and validation. Then,using the tensile tester compression-recovery curves of the rug samples were obtained and experimentally investigated. Results of the theoretical analysis showed that in conventional rug, diameter, length and young’s modulus of pile yarn andapplied load are effective parameters, and in DBP rugs, in addition to those parameters, the gap size and warp yarn diameterare effective parameters on the compression deformation. Also, the experimental results showed that when a gap isintroduced in the rug base, the comfort and compressibility were significantly improved. Besides, increasing the distancebetween the two warp sheets effectively improves the comfort and compressibility of the DBP rugs.