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      • KCI등재

        매복 반곡된 상악 중절치의 외과적 처치에 관한 증례보고

        백병주,윤현두,김미경 大韓小兒齒科學會 1991 大韓小兒齒科學會誌 Vol.18 No.2

        The treatment of unerupted tooth are surgical exposure,orthodontic repositioning ,transplantation and extraction. In treating unerupted tooth,it must be considered to position and dilaceration of unerupted tooth,patient age,requirement of patient. Case mentioned here is autotransplantation of unerupted tooth and dilacerated central incisor. For the successful treatment,it is required space of trancsplanted tooth and good oral hygiene before surgery.We escape trauma of periodontal ligament and cementum during surgery.We observe occlusion,inflammation,development of roots after transplantation.

      • SPME와 GC/MS를 이용한 녹나무 향기성분 특성분석

        원미미,차은주,윤옥경,김남선,김건,이동선 서울여자대학교 자연과학연구소 2007 자연과학연구논문집 Vol.19 No.-

        Recently, land managers have come to realize that, outside Asia, camphor trees grow like street-tree or weeds, infesting forests and displacing native trees. This is because camphor trees are prolific seed producers that do not have serious predators or diseases outside their native range. The camphor tree (Cinnamomum camphora), belongs to lauraceae, is the aromatic evergreen tree from which camphor was derived. Headspace solid-phase microextraction (HS-SPME) and GC-MS were applied for the analysis of volatile fragrances emanated from camphor tree. Divinylbenzene / Carboxen / PDMS fiber was used for HS-SPME adsorption materials. (+)-Camphor (31.00%) and cineol (21.89%) were found as the major volatile aroma components from Chinese camphor tree, whereas (+)-camphor (62.06%) and β-caryophyllene (10.01%) from Japanese camphor tree. Camphor tree is a promising garden tree for well-being.

      • KCI등재

        초등학교 저학년 아동의 글씨쓰기와 실행능력과의 상관관계

        유승복,김진주,김경미 대한감각통합치료학회 2006 대한감각통합치료학회지 Vol.4 No.1

        Objective : The purpose of this study was to examine the correlation between handwriting skills and praxis. Method : Participants consisted of 50 normal children who were the second-grade students at an A elementary school in Kim-hae. They didn't have a visual dysfunction, an auditory dysfunction, and a disease or an injury in arms and hands. They could follow examiners' directions properly. They were administered the Postural Praxis and the Praxis on Verbal Command of the Sensory Integration and Praxis Tests(SIPT)(Ayres, 2000) and the handwriting skill test which was made with reference to foreign literatures. It was conducted from October 19, 2004 to December 17, 2004. The data were analyzed with non-paired t-test, ANOVA, and Pearson correlation coefficient. Results : 1. Total handwriting score and praxis according to gender of children showed the statistically significant differences(p<0.05). 2. Total handwriting score correlated with praxis(p<0.05) and handwriting speed did not correlate with praxis. 3. Postural Praxis and Praxis on Verbal Command according to handwriting groups showed the statistically significant differences(p<0.05). 4. Among the standards of the handwriting skill test, accuracy of letter form, identity of letter size, spacing between letters and words, placing text on lines, error existence, and letter out of regular square correlated with the Postural Praxis(p<0.05), and accuracy of letter form, identity of letter size, and placing text on lines correlated with the Praxis on Verbal Command(p<0.05). Conclusions : The correlation between handwriting skills and praxis will help occupational therapists to provide fundamental and various treatment programs for children who are referred for the poor handwriting. But more studies in handwriting skills and praxis are necessary to decide which component of handwriting skills is related to praxis.

      • KCI등재후보

        미취학 아동에 있어 신체발달, 손목 골밀도 및 영양섭취와의 상관성

        명금희,나현주,최미경,김애정 동아시아식생활학회 2004 동아시아식생활학회지 Vol.14 No.2

        This study was conducted to examine the correlation among growth development, bone mineral density, and nutrient intakes in preschool children. A total of 62 preschool children measured the anthropometric characteristics and the bone mineral density of carpus using DEXA. The questionnaires categorized to determine health status, life style, dietary behaviors, and dietary intakes were filled out by children's mothers. The average ages of the study subjects were 62.4 months in boys and 62.1 months in girls. The birth height and weight of the subjects were 50.9 ㎝ and 3.4 ㎏ in boys and 50.3 ㎝ and 3.3 ㎏ in girls, respectively. The average height, weight, % body fat, and obesity index were 111.7 ㎝, 19.6 kg, 15.0%, -2.1% in boys and 109.4 ㎝, 18.7 ㎏, 17.5%, 0.2% in girls, respectively. The bone mineral density in carpus was 0.25 g/㎠ in boys and 0.24 g/㎠ in girls. Proportions of children having regular meals were 69.0%, 94.7% and 69.0% for breakfast, lunch, and dinner, respectively. The major reasons for irregular meal were poor appetite and lack of time for breakfast and snacks for dinner. Most of the children(52.6%) had breakfast with the whole family together, and all the children had lunch and dinner with a part of the family. Most of the children answered they had snack more than once a day, and 64.3% had an unbalanced diet. The intakes of energy, calcium, iron, zinc, vitamin A, vitamin B₁, niacin, and vitamin C did not meet the Korean RDAs. The intakes of energy, calcium, iron, zinc, vitamin A, vitamin B₁, niacin, and vitamin C did not meet the Korean RDAs. Average bone mineral density in carpus was positively correlated to the body weight, the total body water, the lean body mass, and obesity index, respectively(p<0.01, p<0.01, p<0.01 and p<0.01). The body weight, the total body water, and the lean body mass showed the significant negative correlation with the animal iron intake(p<0.05, p<0.01 and p<0.01). The bone mineral density the distal carpus was negatively correlated to the animal protein intake and the animal iron intake(p<0.05 and p<0.05). And the bone mineral density in the ultradis carpus and the average bone mineral density in the carpus were positively correlated to the plant calcium intake(p<0.05 and p<0.05). Therefore, more systematic studies to investigate the roles of protein, iron, and calcium in growth development of preschool children were required.

      • KCI등재

        Brief Screening for Four Mental Illnesses of the Elderly in Community Mental Health Services: the BS4MI-Elderly

        Yun Kyeong Seon,Moon Bong-Goon,Park Miae,Kim Seong-Ju,Shin Yunmi,Cho Sun Mi,Noh Jai Sung,Lim Ki-Young,Chung Young-Ki,Son Sang Joon,Roh Hyun Woong,Hong Chang Hyung 대한신경정신의학회 2020 PSYCHIATRY INVESTIGATION Vol.17 No.5

        Objective Early detection and proper management of mental illness can help to prevent severe deterioration. However, with limited financial and human resources of community mental health services, it is not practical to carry out all conventional screening tools simultaneously. In this study, we aimed to develop and validate a brief but comprehensive screening questionnaire for four common mental illnesses of the elderly. Methods The brief screening for four mental illnesses of elderly (BS4MI-elderly) is a 14-item binary response questionnaire that covers dementia, depressive disorder, sleep disorder, and hwa-byung. To test validity, we compared conventional scale scores for three groups of participants classified using the BS4MI-elderly. The sensitivity, specificity, predictive value of positive test, likelihood ratio of positive test and internal consistency of the BS4MI-elderly were assessed. Finally, a correlation analysis between the BS4MI-elderly and general mental health scales was conducted. Results A total of 254 participants aged over 65 years were recruited. The BS4MI-elderly showed moderate to high sensitivity for the test that distinguishes the normal group from the risk and disorder groups (dementia: 0.61, depressive disorder: 0.88, sleep disorder: 0.85, hwa-byung: 0.94) and high specificity for the test that distinguishes the disorder group from the normal and risk groups (dementia: 0.91, depressive disorder: 0.93, hwa-byung: 0.84, sleep disorder: 0.84). The BS4MI-elderly also exhibited good internal consistency and significant correlations with general mental health scales. Conclusion The BS4MI-elderly, a brief but comprehensive screening tool, could be a useful instrument for screening the elderly in community mental health services.

      • SCOPUSKCI등재
      • KCI등재

        Simultaneous Determination of Paeoniflorin, Trans-cinnamic Acid, Schisandrin and Glycyrrhizin in So-Cheong-Ryong-Tang by HPLC-DAD and HPLC-ESI-MS

        Mi Kyeong Lee,이기용,Junghyun Park,김승현,Ok-Gyung Choi,Jin-Ho Park,Jung Hee Cho,Do Hoon Kim,Ju Hyun Baek,Mi Hyune Oh,김효진,Sang Hyun Sung 한국생약학회 2010 Natural Product Sciences Vol.16 No.1

        High performance liquid chromatographic method with diode-array detection (HPLC-DAD) has been performed for the simultaneous determination of four marker constituents, paeoniflorin, trans-cinnamic acid, schisandrin and glycyrrhizin in traditional herbal medicinal preparation, So-Cheong-Ryong-Tang (SCRT). The presence of paeoniflorin, trans-cinnamic acid, schisandrin and glycyrrhizin in this decoction was ascertained by retention time, spiking with each authentic standard, UV spectrum and ESI mass spectrum. All four compounds showed good linearity (r2 > 0.998) in a relatively wide concentration ranges. The RSD for intra-day and inter-day precision was less than 3% and the limits of detection (LOD) were less than 30 ng. The mean recovery of each compound was 94.1 - 113.0% with RSD values less than 3.0%. These results suggest that the developed HPLC method is simple, effective and could be readily utilized as a quality control method for commercial SCRT products.

      • KCI등재

        Farnesyl Protein Transferase and Tumor Cell Growth Inhibitory Activities of Lipiferolide Isolated from Liriodendron tulipifera

        Mi Kyeong Moon,Hyun Mi Oh,Byoung-Mog Kwon,Nam-In Baek,Sung-Hoon Kim,Ju Sin Kim,김대근 대한약학회 2007 Archives of Pharmacal Research Vol.30 No.3

        The methanolic extract of the leaves of Liriodendron tulipifera was found to show inhibitory activity towards farnesyl protein transferase (FPTase). Bioassay-guided fractionation of the methanolic extract resulted in the isolation of lipiferolide, an inhibitor of FPTase. This compound inhibited the FPTase activity in a dose-dependent manner, and showed cell growth inhibitory activity against several tumor cells.

      • SCOPUSKCI등재

        Simultaneous Determination of Paeoniflorin and Glycyrrhizin in Sayuk-san by HPLC/DAD

        Lee, Mi-Kyeong,Lee, Ki-Yong,Kim, Seung-Hyun,Jeon, Min-Ji,Cho, Jung-Hee,Oh, Mi-Hyun,Baek, Ju-Hyun,Kim, Hyo-Jin,Sung, Sang-Hyun The Korean Society of Pharmaceutical Sciences and 2009 Journal of Pharmaceutical Investigation Vol.39 No.1

        A high performance liquid chromatographic (HPLC) method for the simultaneous determination of marker constituents, paeoniflorin and glycyrrhizin was established for the quality control of traditional herbal medicinal preparation, Sayuk-san (SYS). Separation and quantification were successfully achieved with a Waters XTerra RP18 column ($5{\mu}m$, $4.6mm\;I.D.{\times}150mm$) by gradient elution of a mixture of acetonitrile and water containing 0.03% phosphoric acid (pH 2.03) at a flow rate of 1.0 mL/min. The diode-array UV/vis detector (DAD) was used for the detection and the wavelength for quantification was set at 230 nm. The presence of paeoniflorin and glycyrrhizin in this decoction was ascertained by retention time, spiking with each authentic standard and UV spectrum. All two compounds showed good linearity ($r^2$>0.996) in a relatively wide concentration ranges. The R.S.D. for intra-day and inter-day precision was less than 7.3% and the limits of detection (LOD) were less than 55.7 ng. The mean recovery of each compound was $102.3{\sim}111.1%$ with R.S.D. values less than 4.6%. This method was successfully applied to the determination of contents of paeoniflorin and glycyrrhizin in three commercial products of SYS. These results suggest that the developed HPLC method is simple, effective and could be readily utilized as a quality control method for commercial SYS products.

      • SCIESCOPUSKCI등재

        Farnesyl Protein Transferase and Tumor Cell Growth Inhibitory Activities of Lipiferolide Isolated from Liriodendron tulipifera

        Moon, Mi-Kyeong,Oh, Hyun-Mi,Kwon, Byoung-Mog,Baek, Nam-In,Kim, Sung-Hoon,Kim, Ju-Sin,Kim, Dae-Keun 대한약학회 2007 Archives of Pharmacal Research Vol.30 No.3

        The methanolic extract of the leaves of Liriodendron tulipifera was found to show inhibitory activity towards farnesyl protein transferase (FPTase). Bioassay-guided fractionation of the methanolic extract resulted in the isolation of lipiferolide, an inhibitor of FPTase. This compound inhibited the FPTase activity in a dose-dependent manner, and showed cell growth inhibitory activity against several tumor cells.

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