大邱地域 學生의 身長 및 體重의 成長에 關한 累年的 調査

申英美,成在鉉 慶北大學校 齒科大學 1984 慶北齒大論文集 Vol.1 No.1

Author investigated and studied longitudinal data of standing height and body weight of 1.049 students (509 males, 540 femles) living in Taegu. This data obtained from physical records of students inspected annualy from six to seventeen years of age. Based on the study, the following are obtained as conclusions. The growth curve showed linear increment tendency until 17 years of age in male, 14 years in female. The annual increment curve of standing height in male revealed the peak value at the 13th year, in female, at the 11th year. The annual increment curve of body weight in male revealed the peak value at the 14th year, in female, at the 12th year. In the standing height and body weight, the growth in male exceeded that in female except 11th and 12th years. The standard deviations of each height and weight showed its declivity in proportion to the annual growth rate.

익산시 고등학생의 식습관 및 군것질 행동에 관한 연구

신인복,신미경,김현영 원광대학교 대학원 2008 論文集 Vol.41 No.-

The aim of this study was to investigate the behaviors of Self-Purchasing Snack(SPS) and the related factors. So, I've investigated and analyzed the general dietary habits and the eating behaviors related to SPS, the subjects of which were 300 high school students living in Iksan(150 boys, 150 girls). The result was as follows. Of going without meal per meal, breakfast 70%, lunch 35.7%, and dinner 50.7% turned out to do it more than three or four times a week and SPS rate of girls was higher than that of boys(P<0.05). I think busy daily schedule lead to irregular dietary habit by making breakfast skipped and this increases the frequency of having junk food and is linked to the cause of skipping lunch or dinner. Also being the loss of appetite, of the reasons for going without meals, took up the most rate and 21.0% of the girls turned to go without meals to help control their weight. For an unbalanced diet, there is no difference between boys and girls, 67.7% of whom turned to have an unbalanced diet more than three or four times and taste(53.2%), of the reason for it, took up the highest rate. For the pace of meal, 53.2% of boys and girls turned to eat quickly. I guess the short mealtime must be the practice because of early school attendance time and pressing lesson. For overeating or not, 24.0% of the subjects responded overeating and boys turned to overeat more than girls(p<0.05). For the frequency of eating between meals, 34.0% of the subjects responded that they did it once or twice a week. Because the increase of eating between meals raised concerns that it may be linked to irregular dietary habit, special education is required at school and at home. For the time of eating between meals, 67.7% of the subjects responded when wanting to eat and the response of girls were higher than that of boys(p<0.05). The place for eating between meals turned to be supermarket(55.6%), the store before the school(20.7%), the store of selling powdered food(16.0%). As preferred junk food, sweet stuff(34.3%) turned to be the most, ramyeon(27.7%), bread(22.3%), milk and dairy products(9.3%). Among boys ramyeon(22.3%) was the most and among girls sweet stuff(24.3%) the most. The rest turned to be similar by and large(p<0.05). When they select junk food, they considered taste(44.3%), mood at the time(23.7%), price(20.0%). For the reason for eating between meals, 53.3% of the subjects responded 'hunger'. I guess this is because of the result of the irregular dietary habit. Throughout the above result, we can see our youth's dietary habit and ways to select junk food be wrong. Therefore, I think policy consideration and nutritional education must be supported at a national level as well as at home to create their right dietary life environment or dietary habit, and to help select junk food properly.

당뇨환자에서 비케톤성 고혈당에 동반하여 나타난 전신성 무도병 1예

신현란,김지훈,박미영 영남대학교 의과대학 2002 Yeungnam University Journal of Medicine Vol.19 No.2

Even thoght the nonketotic hyperglycemia is a metabolic disorder, it complicates hemichorea-hemiballism rarely. Moreover, generalized chorea-ballism associated with nonketotic hyperglycemia in diabetes mellitus is very rare, so has not been reported in Korean literature. Although the precise pathophysiologic mechanisms of these disorders are still poorly understood, deficiency of gamma aminobutyric acid (GABA) in nonketotic hyperglycemia or reduced GABAnergic inhibition by striatal lesion may increase inhibitory output to subthalamic nucleus. These result loss of pallidal inhibition and produce contralateral hemichorea-hemiballism. The striatal lesions, such as transient ischemia with reactive astrocytosis or small amount of petechial hemorrhage, are related with changes of magnetic resonance image (MRI) findings presumably. We report a diabetic old woman who developed generalized chorea-ballismus as a very rare complication of nonketotic hyperglycemia. Her brain MRI showed high signal intensity in left lentiform nucleus and right pallidum on T1 weighted images and low signal intensity in bilateral putamen on T2 weighted images with highly enhanced corresponding lesions on T1 weighted enhancement images.

신이식에서 이식신의 생존분석

오선미,김종학,황평주,구영선,강민규,나기량,김종섭,김성숙,이강욱,신영태,설종구,배진선,손기섭 충남대학교 의과대학 지역사회의학연구소 1997 충남의대잡지 Vol.24 No.2

To investigate the prognostic factors for the survival of transplanted kidney in patients with end-stage renal failure, 59 cases of renal transplantation from September 1986 to Feburary 1997 in Chungnam National University Hospital were analyzed retrospectively. The results were as follows: 1)The mean age of recipients was 33.8 years and that of doners was 38.9 years. The male to female ratio of recipients was 2.5:1, and that of donors was 1.03:1 2) Living related donore(LRD) were 79.6% and living non-related donors were 20.3%. The HLA-identical donors(ID) in LRD were 18.7% and HLA-haploidentical donors(HID) were 61.0%. In living non-related donors(LNRD), mean matched HLA-AB antigens were 1.56 and mean matched HLA-DR antigens were 0.56. 3) The average 5-year patient survival fate was 94%, and average 5-year graft survival rate was 70%. The 5-year graft survival fate of HLA-ID was 100%, and those HLA-HID and LNR were 70% and 36% respectively. 4) Total 33 episodes of acute rejection were found in 45.8% of transplanted patients. The number of acute rejection episode did not show significant difference between LRD and LNRD(P > 0.05). There was no significant difference in MLC between two groups(p > 0.05). 5) In comparison between the 18 patients who lost their graft function in 5 years and 17 patients who are maintaining graft function for more than 5 years, MLC was significantly lower in patients with functioning graft than of patients with non-functioning graft (p < 0.05). The number of rejection episode was also lower in patients with functioning graft than that of the patients with non-functioning graft(p < 0.05). However, there were no significant difference in recepient and donor age and history of pre-transplantation donor specific transfusion between two groups. With the results above, we can speculate that adequate donor selection according to good matched HLA typing and low MLC is very important for graft survival in renal transplantation. Prevention and treatment of acute rejection in renal transplantation is also na important factor for graft survival.

경구용 약독화 장티푸스 생균 백신의 면역원성과 안전성

오미혜,신동한,피대훈,신영규,최병민,손장욱,김익상 대한감염학회 2004 감염과 화학요법 Vol.36 No.1

목적 : Salmonella typhi Ty21a 주로 만든 경구용 약독화 장티푸스 생균 백신 투여 후 위장관의 점막면역 유도를 통한 장티푸스 특이 IgA 항체 양전율과 백신 투여 후 발생한 이상 반응을 조사함으로 백신의 면역원성과 안전성에 대해 알아보고자 이 연구를 시행하였다. 재료 및 방법 : 2001년 7월부터 2002년 3월까지 고려대학교 의과대학 안산병원에서 건강한 6세 이상의 소아, 청소년 및 성인 지원자를 93명을 모집하여 장티푸스 생균 백신(지로티프 캅셀, 보령신약)을 1캅셀씩 2일 간격으로 3회 경구 투여하였다. 투여 시작 후 6, 8, 10일째에 혈액을 채취하여 혈중에서 장티푸스 특이 IgA 분비세포를 측정하는 ELISPOT(enzyme-linked immunospot) 방법으로 면역형성 유무를 검사하였다. 또한 2001년 7월부터 2001년 11월까지 고대안산병원을 포함한 전국 12개 기관에서 모집한 465명의 소아 및 성인남녀 지원자를 대상으로 백신 투여 후 발생한 이상 반응을 조사 분석하였다. 결과 : 1) 지원자 중 항체 양전율 연구를 마친 사람은 6-15세의 16세미만군 42명(남 : 22명, 여 : 20명), 16세이상군 51명(남 : 17명, 여 : 34명), 합계 93명(남 : 39명, 여 : 54명)이었으며, 평균 연령은 16세미만군 11.1±2.5세, 16세이상군 31.6±9.8세였다. 이상 반응 조사가 완료된 사람은 465명(남 : 187명, 여 : 278명)이었으며, 평균 연령은 31.3±16.9세였다. 2) 16세미만군의 항체 양전율은 73.8% (31/42명), 16세이상군의 양전율은 86.3%(44/51명)였으며, 양 군간에 통계적으로 유의한 차이는 없었다. 성, 연령, 알레르기력, 기존 질환, 병용약물 등 대상자의 제반 배경 인자 중에서 통계학적으로 유의하게 양전율에 영향을 미치는 요인은 없었다. 3) 이상 반응의 발현 증례율은 8.6% (40/465명)였으며 증상별로는 복통, 설사, 구역 등 위장관계 이상이 6.5% (30/465명), 무력감, 발열 등의 전신 이상이 1.3% (6/465명), 두통이 0.6% (3/465명), 피부발진이 0.2% (1/465명)에서 나타났다. 백신 복용 횟수에 따른 이상 반응 발현율은 1차 복용 후 5.2% (24/465명), 2차 복용 후 4.5% (21/462), 3차 복용 후 2.6% (12/461)로 처음 복용 후 유의하게 높았다(P<0.05). 대상자의 제반 배경 인자 중에서 통계학적으로 유의하게 이상 반응 발현율에 영향을 미치는 요인은 없었다. 결론 : 경구용 약독화 장티푸스 생균 백신은 장점막 면역유도를 통한 우수한 면역원성을 가지고 있으며, 이상 반응 발생률이 낮고 이상 증상이 경미하여 소아 및 성인 모두에 안전한 백신으로 판단된다. Background : This study is aimed at evaluating immunogenicity by measuring immunoglobulin A (lgA) seroconversion rate through common mucosal immune system and adverse reactions after vaccination of oral live attenuated Salmonella typhi (S. typhi) Ty21a vaccine in Korean population. Methods : A commercially available oral live attenuated vaccine of S. typhi strain Ty21a (Zerotyph® capsule, Boryung Biopharma Co., Seoul, Korea) was given to volunteers, children above 6 years, adolescents, and adults who have never infected with S. typhi nor received S. typhi vaccination. The vaccines were given in three doses, with two day interval between the doses. Seroconversion was determined by ELISPOT (enzyme-linked immunospot) assay. Adverse reactions after vaccination were evaluated in 12 institutions by direct interviewing with vaccinees. Results : A total of 93 volunteers for evaluation of seroconversion were enrolled. Seroconversion rate in the the below 16 year-old group was 73.8% (31/42) and that of over 16 year-old group was 86.3% (44/51), which was not statistically different. Adverse reaction were found in 8.6% (40/465). Gastrointestinal symptoms were most common (6.5%, 30/465). Adverse reactions were found in 5.2% (24/465) after 1st administration, 4.5% (21/462) after 2nd, and 2.6% (12/461) after 3rd. Frequency of adverse reactions was significantly higher after 1st administration (P<0.05). Conclusion : Oral live attenuated S. typhi vaccine, Zerotyph® capsule, had good immnuogenicity and safety through intestinal immune system.

가루녹차(抹茶) 첨가가 증편의 품질에 미치는 영향

정수영,유현희,김금숙,신미경 원광대학교 생활자원개발연구소 2005 생활자원개발연구 Vol.7 No.-

The purpose of this study is to find out the optimal mixing ratios of amounts of Mal-Cha for preparation of Jeung-Pyun through Sensory, Mechanical characteristics test. The proximate composition of Mal-Cha were a 5.46±0.15% of moisture, 4.43±0.11% of total nitrogen, 7.52±0.21% of crude lipid, 8.74% of crude fiber, 8.51±0.09% of ash. Overall quality in 1.5% Jeung-Pyun showed the worst of 0, 0.5, 1.0% Jeung-Pyuns(p<0.05), especially 1.0% Jeung-Pyun had relatively the best overall quality. But the sweetness, sourness, flavor, hardness, moistness were not significantly different among all Jeung- Pyuns. 0, 0.5, 1.0% Jeung-Pyuns showed the best quality of Jeung-Pyun through sensory, mechanical property. Total color difference was increased as amount of Mal-Cha(p<0.001).

말차(抹茶)의 성분 분석

정수영,신미경 원광대학교 2006 論文集 Vol.36 No.-

Mal-Cha(powdered green tea) can be effective in the absorption of ingredients compare with other types of green tea since we take the beverage with powder itself. In the present study, composition of Mal-Cha were investigated to develop functional food. The proximate composition of Mal-Cha were a 5.46±0.15% of moisture, 4.43±0.11% of total nitrogen, 7.52±0.21% of crude lipid, 8.74% of crude fiber, 8.51±0.09% of ash. Contents of minerals(positive ions) in Mal-Cha were K 27.3mg/g, Ca 2.84mg/g, Mg 1.82mg/g, Mn 0.64mg/g, Na 0.19mg/g, Fe 0.08mg/g, Zn 0.03mg/g, Cu 0.005mg/g. Contents of fatty acid in Mal-Cha were C_(18:3)(Linolenic acid) 50.97%, C_(18:2)(Linoleic acid) 21.79%, C_(16:0)(Palmitic acid) 18.45%, C_(18:1)(Oleic acid) 6.50%, C_(18:0)(Stearic acid) 2.28%. Contents of vitamins were β-carotene 301.07mg%, ascorbic acid 148.79mg%.

장기간 보관한 멸균물품의 오염 상태에 관한 연구

주홍순,조순덕,정재심,신동분,임바올라,노은지,이선희,송영미,최정화,백병윤,김미나 대한병원감염관리학회 2003 의료관련감염관리 Vol.8 No.1

한국의 학교보건 향상을 위한 시안

최보율,김지미,신영전,남정현 漢陽大學校 精神健康硏究 1997 精神健康硏究 Vol.16 No.-

말기환자 관리에 대한 의사들의 태도

최윤선,김장욱,신승욱,이영미,이태호,홍명호 가톨릭대학교 가톨릭대학교 간호대학 호스피스 교육연구소 1998 호스피스논집 Vol.3 No.-

Background : Nowadays, it is possible to prolong the life. And to improve the quality of life of the dying patients, they need to receive not only the physical, pscychological, social and spiritual care but also comprehensive and continuous care. Also, doctors have to consider many ethical issues especially in the dying patients. The purpose of this study is to analyze the doctors' attitude of those ethical issues and emphasize the importance of hospice. Methods : During September 1996, doctors who worked for a university hospital participated in this study by responding to the pre-made questionnaire. It dealt with the most suffering pain, the preferred death place, the use of life maintaining equipments, the application of cardiopulmonary resuscitation(CPR) to terminal patients and the doctors' experience and attitude euthanasia. Results : ① The most suffering symptom in dying patients was pain(60.0%). ② The death place was recommended by doctors was home(58.8%) and hospital (15.4%) in order. ③ 56.9% of doctors answered 'the life maintaining equipments isn't needed', 29.2% of doctors answered' according to the case', and 'needed' was 12.3%. ④ The application of CPR to the terminal patients, without the DNR chart, the only 15.4% of doctors answered "Do not CPR." But with the DNR chart, the percents of 'Do not CPR' was increased to 69.2%. The resident group did more CPR than specialist group(p<0.01). ⑤ The 50.8% of doctors agreed with the passive euthanasia. Conclusions : Many doctors follow the family member's opinion in the ethical issues of the dying patients. Euthanasia is forbidden by the law in Korea, but many doctors agree with the passive euthanasia. Hospice can solve the debating ethical issues including the euthanasia.