Nutritional Aspects of Isolated Soy Protein

M. W. Sei,E. C. Henley 한국콩연구회 1993 한국콩연구회소식 Vol.78 No.-

Clinical Utility of Quantitative CT Analysis for Fissure Completeness in Bronchoscopic Lung Volume Reduction: Comparison between CT and Chartis™

Sei Won Lee, M.D., Ph.D,So Youn Shin,Tai Sun Park,Yoon Young Choi,Jong Chun Park,Jina Park,오상영,Namkug Kim,Se Hee Lee,Jae Seung Lee, M.D,Joon Beom Seo,오연목,Sang-Do Lee, M.D., Ph.D.,이상민 대한영상의학회 2019 Korean Journal of Radiology Vol.20 No.7

Objective: The absence of collateral ventilation (CV) is crucial for effective bronchoscopic lung volume reduction (BLVR) with an endobronchial valve. Here, we assessed whether CT can predict the ChartisTM results. Materials and Methods: This study included 69 patients (mean age: 70.9 ± 6.6 years; 66 [95.7%] males) who had undergone CT to assess BLVR eligibility. The ChartisTM system (Pulmonox Inc.) was used to check CV. Experienced thoracic radiologists independently determined the completeness of fissures on volumetric CT images. Results: The comparison between the visual and quantitative analyses revealed that 5% defect criterion showed good agreement. The ChartisTM assessment was performed for 129 lobes; 11 (19.6%) of 56 lobes with complete fissures on CT showed positive CV, while this rate was significantly higher (40 of 49 lobes, i.e., 81.6%) for lobes with incomplete fissures. The size of the fissure defect did not affect the rate of CV. Of the patients who underwent BLVR, 22 of 24 patients (91.7%) with complete fissures and three of four patients with incomplete fissures (75%) achieved target lobe volume reduction (TLVR). Conclusion: The quantitative analysis of fissure shows that incomplete fissures increased the probability of CV on ChartisTM, while the defect size did not affect the overall rates. TLVR could be achieved even in some patients with relatively large fissure defect, if they showed negative CV on ChartisTM.

Nutritional Aspects of Isolated Soy Protein

M.W. Sei,E.C. Henley 한국식품과학회 1993 식품과학과 산업 Vol.26 No.2

갑상샘눈병증과 관련된 사시의 자연경과

이연희,황정민,오세열,Yeon Hee Lee,M,D,Jeong Min Hwang,M,D,Sei Yeul Oh,M,D 대한안과학회 2006 대한안과학회지 Vol.47 No.12

Purpose: This study investigated the natural course of strabismus associated with thyroid ophthalmopathy. Methods: A retrospective review was performed on the medical records of 31 patients with strabismus associated with thyroid ophthalmopathy who had been followed up for more than 6 months and had not received surgery. For the purpose of this study, a significant change of deviation angle was defined as more than 10 prism diopters in the primary position. Results: Forty-two percent of patients showed a significant change in deviation angle during the observation period of 23.8±17.7 months. The direction of the change was vertical in 32%, horizontal in 3%, and vertical and horizontal in 6% of patients. A significant change of deviation angle developed in 30% of patients within 6 months from the initial ophthalmologic examination, in 24% between 6 and 12 months, and in 13% of patients between 12 and 18 months from the initial examination. Conclusions: Although the deviation angle of strabismus associated with thyroid ophthalmopathy tended to stabilize with time, it nonetheless was susceptible to change even 12 months after the initial ophthalmologic examination. In addition, a vertical change in the deviation angle was more frequent than a horizontal change

악성 종양의 추적 관찰 중 PET-CT에서 발견된 갑상선의 우연종

김중석,최소영,노효근,김세중,김윤정<SUP>1<,SUP>,현인영<SUP>2<,SUP>,김영모<SUP>3<,SUP>,조영업,Joong Suck Kim,M,D,So-young Choi,M,D,Ph,D,Hyo Keun No,M,D,Sei Joong Kim,M,D,Ph,D,Youn Jeong Kim,M,D,Ph,D,<SUP>1<,SUP>,In Young Hyun 대한갑상선-내분비외과학회 2010 The Koreran journal of Endocrine Surgery Vol.10 No.4

Purpose: The incidence of thyroid cancer is increasing in Korea, partially owing to the development of diagnostic tools. Positron emission tomography (PET)-computed tomography (CT), in particular, has generally been used for evaluation of metastasis and follow-up of malignancy. Methods: We retrospectively investigated 2,833 patients with PET-CT for metastasis work-up or cancer follow-up, which was performed between January 1998 and May 2008 at Inha University Hospital. Of them, abnormal thyroid findings were discovered in 181 patients and we studied the result of further evaluation or follow-up PET-CT. Results: Thyroid cancer was diagnosed in 26 patients, including metastatic cancer in 3 patients, and non-operated primary cancer in 2 patients. Other 21 patients received operation, which in all histopathologically revealed papillary carcinoma. The mean age of the 21 patients was 55.4 years. Nine patients had a history of radiotherapy. The site of malignant nodule was discordant between PET-CT and histopathologic result in 6 patients. The mean size of malignant nodules was 9.45 mm (0.1∼23 mm) with microcarcinoma in 10 patients (47.6%). The mean interval between diagnoses was 15.8 months, and in 4 patients operations for two malignancies were performed in a same day. The incidence of thyroid cancer was significantly high in female patients, but the differences of incidence among different cancer groups were not significant for female patients. Conclusion: Early diagnosis of synchronous or secondary thyroid cancer by PET-CT in cancer patients can make early treatment and better strategies for multiple malignancies possible. (Korean J Endocrine Surg 2010;10:249-255)

Anti-calcification of Bovine Pericardium for Bioprosthetic Heart Valves after Surface Modification with Hyaluronic Acid Derivatives

Hahn Sei Kwang,Ohri Rachit,Giachelli Cecilia M. The Korean Society for Biotechnology and Bioengine 2005 Biotechnology and Bioprocess Engineering Vol.10 No.3

Surface modification of glutaraldehyde fixed bovine pericardium (GFBP) was success­fully carried out with hyaluronic acid (HA) derivatives. At first, HA was chemically modified with adipic dihydrazide (ADH) to introduce hydrazide functional group into the carboxyl group of HA backbone. Then, GFBP was surface modified by grafting HA-ADH to the free aldehyde groups on the tissue and the subsequent HA-ADH hydrogel coating. HA-ADH hydrogels could be prepared through selective crosslinking at low pH between hydrazide groups of HA-ADH and crosslinkers containing succinimmidyl moieties with minimized protein denaturation. When HA­ADH hydrogels were prepared at low pH of 4.8 in the presence of erythropoietin (EPO) as a model protein, EPO release was continued up to $85\%$ of total amount of loaded EPO for 4 days. To the contrary, only $30\%$ of EPO was released from HA-ADH hydrogels prepared at pH=7.4, which might be due to the denaturation of EPO during the crosslinking reaction. Because the carboxyl groups on the glucuronic acid residues are recognition sites for HA degradation by hyaluronidase, the HA-ADH hydrogels degraded more slowly than HA hydrogels prepared by the crosslinking reaction of divinyl sulfone with hydroxyl groups of HA. Following a two-week subcutaneous implantation in osteopontin-null mice, clinically significant levels of calcification were observed for the positive controls without any surface modification. However, the calcification of surface modified GFBP with HA-ADH and HA-ADH hydrogels was drastically reduced by more than $85\%$ of the positive controls. The anti-calcification effect of HA surface modification was also confirmed by microscopic analysis of explanted tissue after staining with Alizarin Red S for calcium, which followed the trend as observed with calcium quantification.

Clinical Report of 46 Intracranial Tumors with LINAC Based Stereotactic Radiosurgery

윤세철(Yoon Sei C),서태석(Suh Tge S),김성환(Kim Sung W),강기문(Kang Ki M),김연실(Kim Yun S),최병옥(Byung O Choi),장홍석(Jang Hong S),최규호(Choi Kyo H),김문찬(Kim Moon C),신경섭(Shinn Kyung S) 대한방사선종양학회 1993 Radiation Oncology Journal Vol.11 No.2

가톨릭 의과대학 강남성모병원 치료방사선과에서는 1988년 7월부터 1992년 12월 사이에 뇌종양 환자 45명의 뇌내 46개 병소에 대한 뇌정위다방향방사선치료를 실시하였으며, 이들에 대한 영상학적 및 임상적 추적조사 결과를 후향적으로 분석하였다. 뇌종양에 대한 뇌정위다방향방사선치료는 병소가 생명중추에 인접되어 있거나 다른 전신질환과 함께 있어 종양의 수술적 제거가 어려운 경우, 수술후 잔류 병소가 남아 있거나 재발된 경우, 또는 종래 부터 해오던 방사선치료에도 불구하고 잔류병소가 남아있거나 환자가 수술을 거부할 경우 등에서 실시하게 된다. 이는 수술이나 유사한 다른 치료와 비교하여 동일한 치료효과를 얻으면서도 간편하고 비침습적 이며 또한 상대적으로 저렴한 치료 경비가 소요됨으로, 최근 방사선치료장비 및 치료계획 프로그램의 개발과 함께 그 치료성적이 관심의 대상이 되고 있다. 환자 분포는 남녀 비가 22:33 이며, 연령 분포는 5-74세 (중앙값 : 43세)이었고, 추적조사 기간은 2-55개월 (중앙값 : 35개월)이었다. 6 MV 선형 가속기를 사용하여 조사야 용적은 0.13-42.88㎤(중앙값 : 7.26㎤)이었으며, 최대치료선량은 5-35.5 Gy(중앙값 : 20.9 Gy)이었다. 종양 별로는 뇌하수체종양15예, 청각신경종 8예, 수막종 7예, 뇌교종 6예, 두개인두종 4예, 송과선종 3예, 혈관아세포종 2예, 및 뇌전이 암 1예 씩이었다. 총 46예 중 18예(39.1%)에서 추적 영상검사상 종양의 소실 및 위축을 관찰하였으며, 10예(34.8%)에서는 종양크기의 정지상태를 나타냈다. 임상적으로는 34예(73.9%)에서 방사선치료 전보다 양호한 전신상태 및 수행능력을 유지하고 있었으며, 이중 4예 (8.7%)에서는 추적 검사상 종양 크기가 약간 커졌음에도 불구하고 임상적으로는 안정된 상태이었다. 영상학적으로나 임상적으로 악화된 경우는 2예(4.4%)에서 있었다. 치료에 따르는 부작용으로는 치료 직후, 일시적 두통을 호소하였으나 스테로이드 및 진통제 투여로 개선되었으며 경미한 일시적 탈모를 3예(6.6%)에서 경험하였으며 향후 좀더 정밀 추적검사가 필요할 것으로 생각된다. Between July 1988 and December 1992, we treated 45 patients who had deep seated inoperable or residual and/or recurrent intracranial tumors using LINAC based stereotactic radiosurgery at the Department of Therapeutic Radiology, Kangnam St. Mary's Hospital, Catholic University Medical College. Treated intracranial tumors included pituitary tumors (n=15), acoustic neurinomas (n=8), meningiomas (n=7), gliomas (n=6), craniopharyngiomas (n=4), pinealomas (n=3), hemangioblastomas (n=2), and solitary metastatic tumor from lung cancer (n=1). The dimension of treatment field varied from 0.23 to 42.88㎤ (mean; 7.26㎤). The maximum tumor doses ranging from 5 to 35.5 Gy (mean; 29.9 Gy) were given, and depended on patients' age, target volume, location of lesion and previous history of irradiation. There were 22 male and 23 female patients. The age was varied from 5 to 74 years of age (a median age; 43 years). The mean duration of follow-up was 35 months (2~55 months). To date, 18 (39.1%) of 46 intracranial tumors treated with SRS showed absent or decrease of the tumor by serial follow-up CT and/or MRI and 16 (34.8%) were stationary, e.g. growth arrest. From the view point of the clinical aspects, 34 (73.9%) of 46 tumors were considered improved status, that is, alive with no evidence of active tumor and 8 (17.4%) of them were stable, alive with disease but no deterioration as compared with before SRS. Although there showed slight increase of the tumor in size according to follow-up imagings of 4 cases (pituitary tumor 1, acoustic neurinomas 2, pinealoma 1), they still represented clinically stable status. Clinically, two (4.4%) Patients who were anaplastic astrocytoma (n=1) and metastatic brain tumor (n=1) were worsened following SRS treatment. So far, no serious complications were found after treatment. The minor degree headache which could be relieved by steroid or analgesics and transient focal hair loss were observed in a few cases. There should be meticulous long term follow-up in all cases.

Investigation of magnetic phase transition on the layered inorganic-organic hybrid perovskites (C₆H₅CH₂CH₂NH₃)₂MnCl₄ by single-crystal neutron diffraction

Park, Garam,Oh, In-Hwan,Park, J.M. Sungil,Park, Seong-Hun,Hong, Chang Seop,Lee, Kwang-Sei Elsevier 2018 PHYSICA B-CONDENSED MATTER - Vol.551 No.-

<P><B>Abstract</B></P> <P>In previous work, the inorganic-organic hybrid perovskite system (C<SUB>6</SUB>H<SUB>5</SUB>CH<SUB>2</SUB>CH<SUB>2</SUB>NH<SUB>3</SUB>)<SUB>2</SUB>MnCl<SUB>4</SUB> exhibit well-isolated 2D Heisenberg antiferromagnetc properties, including a canted antiferromagnet below T<SUB>N</SUB> = 44.3 K. This study looked at the antiferromagnetic spin structure of the titled compound using single-crystal neutron diffraction. At 43 K, a new forbidden (−1 0 0) peak was observed and this peak showed a clear temperature dependence. Additionally, non-integer forbidden peaks were found. It was assumed that the magnetic cell was equal to the chemical cell for Mn-PEA system (<I>k</I> = 0). No magnetic peaks were observed along the c-axis. From this data it can be assumed that the spin is parallel to the <I>c</I>-axis. This result coincides with previous magnetic measurement studies. According to Turov, in the case of an antiferromagnetic structure with weak ferromagnetism, the magnetic cell should be equal to the chemical cell. Our neutron diffraction measurement and former study strongly support the hypothesis of Turov.</P>

Optimal configuration of energy supply system in a microgrid with steam supply from a municipal waste incinerator

S. Bando,H. Asano,K. Sasajima,N. Odajima,M. Sei,T. Ogata 전력전자학회 2011 ICPE(ISPE)논문집 Vol.2011 No.5

We present the optimal design of energy supply system of a urban microgrid by using a Mixed Integer Non Linear Programming model. We have conducted a feasibility study of energy supply system using waste steam from incinerator plants via a steam distribution network in the urban redevelopment project area in Tokyo as a case study. We compared the optimal configuration of both of a district heat and cooling (DHC) system and a microgrid system with sufficient self generation capacity as an energy supply system in the redevelopment area. We present the economic and environmental effectiveness of the microgrid with large scale cogeneration and steam supply from incinerator plants as unharnessed energy. Large scale cogeneration with high efficiency has capability to reduce 20% of primary energy consumption and 2% of the amount of CO₂ emissions compared with a new constructed DHC system. Steam supply from incinerator plants has capability to reduce about 3% of CO₂ emissions. Pay-back time of the microgrid for commercial and residential area is 4 to 6 years. The microgrid with large scale gas engine generators is economically viable.

심폐기능 허약자를 위한 보행보조장치 제어기 개발

강성재(S. J. Kang),김규석(G. S. Kim),박세훈(S. H. P),문무성(M. S. Mun),서수원(S. W. Sei),김진국(J. K. Kim),류제청(J. C. Ryu) 한국재활복지공학회 2010 재활복지공학회논문지 Vol.4 No.1

심폐기능 허약자의 경우 다른 보행기능은 정상이지만 산소 공급에 문제가 발생된 경우로서, 에너지 소모를 최소한으로 줄여주는 보행보조 시스템이 필요하다. 심폐기능 허약자의 보행을 원활히 보조하기 위하여 본 연구에서는 고관절에 부착된 DC모터를 이용하여, 보행시 고관절 굴곡 및 신전을 제어하는 시스템을 고안하였다. 두 개의 모터를 좌우 고관절에 부착되어 정상 보행패턴을 기준으로 고관절의 굴곡과 신전의 설정각도를 정의하고 보행을 보조한다. 실험결과 보행보조에 의한 에너지 소모도 감소는 14.8%이었다. Case of patients with weakness in cardiopulmonary system, other ambulatory function is normal, but oxygen supply function is problem. So they need reduce energy consumption for gait by assistance system. In this study, we designed and developed walking assistant device which helps flexion and extension of hip joint for cardiopulmonary patients. There are two motors, each at the left and right side of pelvis, providing torque to the hip joint. The target angle of the flexion and extension in the hip joint is set according to the normal gait. As a result, reduction of energy consumption was 14.8% by gait assistive device