Manganese-based spinel adsorbents for lithium recovery from aqueous solutions by electrochemical technique

Honglong Zhan,Yingjun Qiao,Zhiqiang Qian,Jun Li,Zhijian Wu,Xiaogang Hao,Zhong Liu 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.114 No.-

The manganese-based spinel adsorbent (HMO) refers to lithium-ion adsorbents derived from the spinellithium manganese oxide (LMO). Two types of lithium ions extraction composite films composed of HMO(HMn2O4 and H1.6Mn1.6O4) are successfully prepared by the blade coating method. Based on the excellentLi+ selectivity of HMO and the outstanding conductivity of conductive carbon black (C), HMO/C films arecarried out to extract lithium by electrochemically switched ion exchange (ESIX) technique. HMO has acertain adsorption capacity for Li+ when the Li+ concentration is close to the actual brine, and the adsorptioncapacity of HMn2O4 and H1.6Mn1.6O4 is 24.56 mg/g and 34.40 mg/g, respectively. HMO showed goodselectivity for Li+ in multiple metal ions solution. The capacity of HMn2O4 and H1.6Mn1.6O4 keep 80% and86% of the initial values after 5 cycles, respectively. The inherent different lithium occupied leads to thedifference of electrical-adsorption abilities between HMn2O4 and H1.6Mn1.6O4. H1.6Mn1.6O4 has a broadapplication prospect in lithium extraction from salt lake brine due to its lower application voltage, largeadsorption capacity and superior stability.

Advances in CRISPR-Cas systems for RNA targeting, tracking and editing

Wang, Fei,Wang, Lianrong,Zou, Xuan,Duan, Suling,Li, Zhiqiang,Deng, Zixin,Luo, Jie,Lee, Sang Yup,Chen, Shi Elsevier 2019 BIOTECHNOLOGY ADVANCES Vol.37 No.5

<P><B>Abstract</B></P> <P>Clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated protein (Cas) systems, especially type II (Cas9) systems, have been widely used in gene/genome targeting. Modifications of Cas9 enable these systems to become platforms for precise DNA manipulations. However, the utilization of CRISPR-Cas systems in RNA targeting remains preliminary. The discovery of type VI CRISPR-Cas systems (Cas13) shed light on RNA-guided RNA targeting. Cas13d, the smallest Cas13 protein, with a length of only ~930 amino acids, is a promising platform for RNA targeting compatible with viral delivery systems. Much effort has also been made to develop Cas9, Cas13a and Cas13b applications for RNA-guided RNA targeting. The discovery of new RNA-targeting CRISPR-Cas systems as well as the development of RNA-targeting platforms with Cas9 and Cas13 will promote RNA-targeting technology substantially. Here, we review new advances in RNA-targeting CRISPR-Cas systems as well as advances in applications of these systems in RNA targeting, tracking and editing. We also compare these Cas protein-based technologies with traditional technologies for RNA targeting, tracking and editing. Finally, we discuss remaining questions and prospects for the future.</P> <P><B>Highlights</B></P> <P> <UL> <LI> RNA targeting and editing are becoming increasingly important </LI> <LI> CRISPR-Cas systems are advancing for RNA targeting, tracking and editing </LI> <LI> The type VI CRISPR-Cas systems are useful for RNA-guided RNA targeting </LI> <LI> Use of Cas9 and Cas13 will advance RNA-targeting technologies </LI> </UL> </P>

Identification of MicroRNAs as potential biomarkers for detecting ischemic stroke

Li Kexin,Shen Li,Zheng Pingping,Wang Yanjun,Wang Lijuan,Meng Xiaoli,Lv Yaogai,Xue Zhiqiang,Guo Xin,Zhang Anning,Pan Pan,Bi Chunli,Chen Yang,Feng Tianyu,Li Bo,Jin Lina,Yao Yan 한국유전학회 2022 Genes & Genomics Vol.44 No.1

Background: Increasing epidemic of ischemic stroke (IS) makes it urgent to understand the pathogenesis and regulatory mechanism, previous studies have described microRNAs (miRNAs) is part of the brain's response to ischemia. Objective: The aim of this study was to screen potential biomarkers for the prediction and novel treatment of IS. Methods: Differentially expressed miRNAs were screened from three newly diagnosed IS patients and three controls by RNA sequencing technology. Furthermore, target prediction databases were then used to analysis the target genes of different expressed miRNAs, and the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway database were used to identify the functions and the main biochemical and signal pathways of differentially expressed target genes. Results: Our results revealed that 27 miRNAs were differentially expressed in IS, among which, hsa-miR-659-5p was the most highly increased and was first found to be associated with IS. In addition, KEGG pathway analyses showed that differentially expressed miRNAs were mainly significantly enriched in lysosome pathway, cytokine-cytokine receptor interaction pathway, spliceosome pathway, base excision repair pathway. Conclusions: miRNAs were involved in IS pathogenesis, and hsa-miR-659-5p, hsa-miR-151a-3p and hsa-miR-29c-5p as the three highest |log2FoldChange| regulation in this study, which may be the biomarkers of IS and need further study.

Comprehensive evaluation method of groundwater environment in a mining area based on fuzzy set theory

Zhiqiang Li,Binghua Zhou,Debin Teng,Wei-min Yang,Daohong Qiu 한국자원공학회 2018 Geosystem engineering Vol.21 No.2

Disordered mining activities have significantly affected the eco-geological environment of groundwater in mining area. Based on the fuzzy set theory, this paper considered three factors: the quantity of groundwater resources, groundwater environmental quality and groundwater vulnerability, and established a multi-index and multi-parameter non-linear evaluation system to make a comprehensive evaluation of the groundwater environment in the mining area. The results showed that the groundwater eco-geological environmental issues in this region were serious. The distribution area of poor quality of groundwater environment was very large, accounting for 72.5% of the studied area, and it mainly distributed in the middle and southern regions. The areas with general groundwater quality covered about 19.0% and mainly distributed in the central and northern parts in a strip shape. The areas with good groundwater quality covered about 8.5% and distributed sporadically. Moreover, in the study area, because the groundwater vulnerability was at a high level and the groundwater environmental quality was poor, the groundwater was extremely susceptible to contamination. Therefore, the groundwater environment in the area should be significantly protected during coal mining. In addition, the predicted results can provide a scientific reference for the planning and sustainable development of large coalfields.

DeepPTP: A Deep Pedestrian Trajectory Prediction Model for Traffic Intersection

( Zhiqiang Lv ),( Jianbo Li ),( Chuanhao Dong ),( Yue Wang ),( Haoran Li ),( Zhihao Xu ) 한국인터넷정보학회 2021 KSII Transactions on Internet and Information Syst Vol.15 No.7

Compared with vehicle trajectories, pedestrian trajectories have stronger degrees of freedom and complexity, which poses a higher challenge to trajectory prediction tasks. This paper designs a mode to divide the trajectory of pedestrians at a traffic intersection, which converts the trajectory regression problem into a trajectory classification problem. This paper builds a deep model for pedestrian trajectory prediction at intersections for the task of pedestrian short-term trajectory prediction. The model calculates the spatial correlation and temporal dependence of the trajectory. More importantly, it captures the interactive features among pedestrians through the Attention mechanism. In order to improve the training speed, the model is composed of pure convolutional networks. This design overcomes the single-step calculation mode of the traditional recurrent neural network. The experiment uses Vulnerable Road Users trajectory dataset for related modeling and evaluation work. Compared with the existing models of pedestrian trajectory prediction, the model proposed in this paper has advantages in terms of evaluation indicators, training speed and the number of model parameters.

PHARMACOKINETIC PROFILES OF ANTIBIOTICS IN FLATFISH

Zhiqiang Chang,Jian Li,Qianqian Zhai,Jitao Li,Ping Liu 한국수산과학회 양식분과 2015 한국수산과학회 양식분과 학술대회 Vol.2015 No.5

Estimation of Jointed Rock Mass Parameters Based on the Hoek-Brown Failure Criterion : A Case Study from the Underground Powerhouse of Baihetan Hydropower Station

( Zhiqiang Li ),( Guofeng Liu ) 대한지질공학회 2019 대한지질공학회 학술발표회논문집 Vol.2019 No.2

Taking the columnar jointed basalt of Baihetan hydropower station which will be the second largest hydropower station in the world as a research object, this paper attempts to estimate the parameters of jointed rock mass with Hoek-Brown failure criterion. The parameters of H-B failure criterion, i.e. Geological Strength Index (GSI), uniaxial compressive strength (σci), the disturbance coefficient (D) and mi, can be obtained from the results of laboratory tests including uniaxial compression test and Brazilian splitting test, as well as in-situ tests such as single-hole acoustic wave, drilling for core and borehole camera. The main deformation and intensity parameters of rock mass are estimated before rock mass excavation. Flac3D numerical simulations are carried out with these parameters. The results of numerical simulation and field monitoring information of loose ring and deformation are contrasted. The effect of GSI, σci, D and mi on loose ring and deformation are analyzed with the single factor sensitivity analysis method. The influence of the range of GSI on the results of rock mass parameters estimation is discussed. Some conclusions we can get from the research. Firstly, the numerical simulation results are in agreement with the field information more than 80%, showing that the parameters of the cylindrical jointed rock mass can be better reflected by the H-B failure criterion. Secondly, the sensitivity of H-B parameters on loose ring and deformation from high to low are GSI, σci, D and mi. This study can provide important support for the stability analysis of Baihetan hydropower station.

Stability analysis of prestressed stayed steel columns with split-up crossarm systems

Pengcheng Li,Zhiqiang Li,Bin Jia,Hao Wang 국제구조공학회 2020 Steel and Composite Structures, An International J Vol.34 No.5

A Prestressed stayed steel column is an efficient and lightweight way with regard to enhancing the stability behaviour of a compression column. In the past, researchers primarily concentrated on investigating the behaviour of stayed steel columns with horizontal crossarms. However, this article focuses on prestressed stayed steel columns with split-up crossarm system, in which the crossarms are aslant and rotational symmetrically arranged. A mathematical formula calculating the optimal pretension that corresponds to the maximum critical buckling load was established according to geometric analysis based on the small deformation assumption. It was demonstrated that critical buckling mode of this stayed column is different from the one with horizontal crossarms. The governing imperfection direction that should be adopted in the nonlinear buckling analysis was determined in this work. In addition, the effects of crossarm inclination, stay diameter, and crossarm length on the stability behaviour were investigated. An influencing factor denotes the ratio of the load carrying capacity of the prestressed stayed steel column to the Euler load of the main column was also obtained.

Researches on Ominimedia Development Strategies and Core Competitive Strength Improvement in the Context of Triple Play

Xu Zhiqiang,He Jialiang,Liu Tong,Li Haidong 보안공학연구지원센터 2015 International Journal of Future Generation Communi Vol.8 No.1

In the context of triple play Ominimedia is not just the simple combination of various media, but the aggregation of all media with different features, communication power and influences,and the interaction and mutual fusion among media of different forms and functions. This paper, based on the development trend of triple play, focused on the theme of Ominimedia, studied the traditional media development strategies to Ominimedia and analyzed in detail the strategies of cloud, tube, end and content aggregation. At the same time it explored the strategies for Ominimedia core competitive strength improvement from multiple dimensions of 3D media, communication channel, AirSharing and brand operation with the expectation of offering references to Ominimedia globalization in the context of triple play.

Comparison between laparoscopic and abdominal radical hysterectomy for stage IB1 and tumor size <2 cm cervical cancer with visible or invisible tumors: a multicentre retrospective study

Pengfei Li,Lan Chen,Yan Ni,Jiaqi Liu,Donglin Li,Jianxin Guo,Zhihua Liu,Shuangling Jin,Yan Xu,Zhiqiang Li,Lu Wang,Xiaonong Bin,Jinghe Lang,Ping Liu,Chunlin Chen 대한부인종양학회 2021 Journal of Gynecologic Oncology Vol.32 No.2

Objective: To compare 5-year disease-free survival (DFS) and overall survival (OS) rates oflaparoscopic radical hysterectomy (LRH) and abdominal radical hysterectomy (ARH) forstage IB1 and tumor size <2 cm with visible or invisible tumors. Methods: We retrospectively compared the oncological outcomes of 1,484 cervical cancerpatients with IB1 and tumor size <2 cm on final pathology, who received ARH (n=899) or LRH(n=585) between January 2004 and December 2016. Patients were divided into visible tumorsubgroup (ARH: n=668, LRH: n=444) and invisible tumor subgroup (ARH: n=231, LRH:n=141) according to tumor type. Results: LRH and ARH showed similar 5-year DFS and OS rates (93.3% vs. 93.1%, p=0.997;96.2% vs. 97.5%, p=0.351) in total study population. LRH was not associated with worse5-year DFS rate (hazard ratio [HR]=0.96; 95% confidence interval [CI]=0.58–1.58; p=0.871)or OS rate (HR=1.37; 95% CI=0.65–2.89; p=0.409) by multivariable analysis. In the visibletumor subgroups, LRH and ARH showed similar 5-year DFS and OS rates (91.9% vs. 91.9%,p=0.933; 95.0% vs. 96.9%, p=0.276), and LRH was not associated with worse 5-year DFS orOS rate (p=0.804, p=0.324). In the invisible tumor subgroups, LRH and ARH also showedsimilar 5-year DFS and OS rates (97.3% vs. 97.1%, p=0.815; 100% vs. 99.5%, p=0.449), andLRH was not associated with worse 5-year DFS rate (p=0.723). Conclusions: Among patients with stage IB1 and tumor size <2 cm, whether the tumor isvisible or not, the oncological outcomes of LRH and ARH among cervical cancer patients arecomparable. This suggests that LRH may be suitable for stage IB1 and tumor size <2 cm withvisible or invisible tumors.Trial Registration: International Clinical Trials Registry Platform Identifier: CHiCTR180017778