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양수룡,이춘석 진주산업대학교 건설기술연구소 1998 건설기술연구소보 Vol.1 No.-
하도내에는 많은 종류의 식생이 분포하며, 이들의 기능은 지금까지 대단히 부정적인 요소로 판단되었다. 즉 홍수시 홍수단면의 감소뿐 아니라 국부세굴에 의한 제방붕괴 등을 유발하는 것으로 알려져 있다. 반면 최근의 경향은 하천내의 식생이 하천이라는 자연생태계를 보호하고, 친수공간을 제공하며 나아가 하천제방의 안정에도 상당한 도움을 주는 것으로 알려져 있다. 이는 하천제방에 위치한 나무의 경우 단단한 뿌리조직의 발달로 인하여 홍수시 소류력에 대한 저항력을 증가시키며, 제방사면의 밀도를 증가시키기 때문인 것으로 밝혀져 있다. There are many kind of trees and grasses in natural stream. Vegetation(trees) is negative effects on prevention flood and structure - bank, bridge. Vegetation in stream channel reduces the cross-section and hydraulic conductivity of channel and the flow velocity is enlarged and local scouring by tree is occured and destroyed the bank. or other structure in stream. But in recently research, the effect of tree is more positive. The tree near the channel provides shadow in water and prohibites the rising water temperature and provides more comfortable habitat to fish and the tree on the bank makes the soil density high and provides the resistance to scouring.
A genome-wide association study of a coronary artery disease risk variant.
Lee, Ji-Young,Lee, Bok-Soo,Shin, Dong-Jik,Woo Park, Kyung,Shin, Young-Ah,Joong Kim, Kwang,Heo, Lyong,Young Lee, Ji,Kyoung Kim, Yun,Jin Kim, Young,Bum Hong, Chang,Lee, Sang-Hak,Yoon, Dankyu,Jung Ku, Hy Springer-Verlag 2013 Journal of human genetics Vol.58 No.3
<P>Although over 30 common genetic susceptibility loci have been identified to be independently associated with coronary artery disease (CAD) risk through genome-wide association studies (GWAS), genetic risk variants reported to date explain only a small fraction of heritability. To identify novel susceptibility variants for CAD and confirm those previously identified in European population, GWAS and a replication study were performed in the Koreans and Japanese. In the discovery stage, we genotyped 2123 cases and 3591 controls with 521 786 SNPs using the Affymetrix SNP Array 6.0 chips in Korean. In the replication, direct genotyping was performed using 3052 cases and 4976 controls from the KItaNagoya Genome study of Japan with 14 selected SNPs. To maximize the coverage of the genome, imputation was performed based on 1000 Genome JPT+CHB and 5.1 million SNPs were retained. CAD association was replicated for three GWAS-identified loci (1p13.3/SORT1 (rs599839), 9p21.3/CDKN2A/2B (rs4977574), and 11q22.3/ PDGFD (rs974819)) in Koreans. From GWAS and a replication, SNP rs3782889 showed a strong association (combined P=3.95 10(-14)), although the association of SNP rs3782889 doesn't remain statistically significant after adjusting for SNP rs11066015 (proxy SNP with BRAP (r(2)=1)). But new possible CAD-associated variant was observed for rs9508025 (FLT1), even though its statistical significance did marginally reach at the genome-wide a significance level (combined P=6.07 10(-7)). This study shows that three CAD susceptibility loci, which were previously identified in European can be directly replicated in Koreans and also provides additional evidences implicating suggestive loci as risk variants for CAD in East Asian.</P>
Extracranial anaplastic meningioma presenting as a solitary scalp nodule
( Seung Soo Lee ),( Gi Ung Ha ),( Jeong Hyun Hwang ),( Ho Yun Chung ),( Man-hoon Han ),( Jun Young Kim ),( Kyung Duck Park ),( Yong Hyun Jang ),( Weon Ju Lee ),( Seok-jong Lee ),( Dae-lyong Ha ) 대한피부과학회 2023 대한피부과학회 학술발표대회집 Vol.74 No.2
The long-term retrospective study in patients with en coup de sabre
( Dae-lyong Ha ),( Woo-il Kim ),( Min-young Yang ),( Won-ku Lee ),( Tae-wook Kim ),( Sung-min Park ),( Hyun-joo Lee ),( Hoon-soo Kim ),( Hyun-chang Ko ),( Byung-soo Kim ),( Moon-bum Kim ),( Gun-wook K 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.2
Background: En coup de sabre (ECDS) is a uncommon subtype of linear morphea, generally located on the forehead or frontoparietal scalp, resembling a stroke from a sword. Though clinical characteristics of ECDS are well-described, the clinical data about Korean ECDS need to be investigated. Objectives: To investigate the clinical characteristics and treatment efficacy of ECDS in Korea. Methods: We retrospectively reviewed medical records, and clinical photos of 21 patients diagnosed with ECDS by skin biopsy in the Pusan National University Hospital (Busan and Yangsan) over the 13 year period (2005-2018). Results: We found 21 cases of ECDS patients (mean age, 31.6 years, range in 4 to 55 years), consisting of 7 males (33.3%) and 14 females (66.7%), with mean disease duration 3.37 years (range in 1 month to 20 years). The clinical features at presentation were hyperpigmentation in 10 patients (47.6%), erythema in 6 patients (28.6%) and hypopigmentation in 5 patients (23.8%). Regarding central nervous system (CNS) involvement, only two patients (9.5%) showed headaches and there was no patients who showed any intracranial abnormality. Of 20 patients who received treatment, most were treated with antimalarial agents (45%), topical tacrolimus (25%) or methotrexate (20%). Conclusion: Our study revealed that CNS involvement occurs less frequently in Korean patients than previous literatures. The result of this study could be helpful for dermatologist to understand ECDS in Korea.
Lichen planus pigmentosus in Korea: a single centre experience and literatures review
( Dae-lyong Ha ),( Woo-il Kim ),( Min-young Yang ),( Won-ku Lee ),( Tae-wook Kim ),( Sung-min Park ),( Hyun-joo Lee ),( Gun-wook Kim ),( Hoon-soo Kim ),( Hyun-chang Ko ),( Byung-soo Kim ),( Moon-bum K 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.2
Background: Lichen planus pigmentosus (LPP), a uncommon variant of lichen planus, is reported in various ethnic groups. Though the clinical characteristics of LPP are well-described in the Indian and Middle East patients, the clinical data of LPP in Korean are not well known yet. Objectives: We performed the present study to investigate the clinical characteristics of LPP in Korea. Methods: We retrospectively reviewed medical records, and clinical photos of 38 patients diagnosed as LPP by skin biopsy in the Pusan National University Hospitals (Busan and Yangsan) over the 12 years (2006-2018). And we also reviewed other Korean LPP patients collected by pubmed and Kormed searching. Results: We found 53 cases of Korean LPP patients (mean age; 46 years, range: 9 ~ 79 years), consisting of 23 males (43.4%) and 30 females (56.6%) and mostly affecting the trunk (75.5%). The most common distribution pattern was inversus (20/53, 37.8%), followed by linear (19/53, 35.8%) and diffuse (14/53, 26.4%). Itching accompanied in 32 patients (60.4%). Of the 44 patients who underwent treatment, 3 patients (6.8%) showed improvement, 21 patients (47.8%) showed partial response and 20 patients (45.5%) showed no response. Conclusion: Our study revealed that LPP occurs frequently in Korean patients. Especially, inverse type LPP and linear LPP is more common in Korean than other ethnic groups. The result of our study might be helpful for dermatologist to understand characteristics of LPP in Korea.
( Dae-lyong Ha ),( Woo-il Kim ),( Min-young Yang ),( Won-ku Lee ),( Tae-wook Kim ),( Sung-min Park ),( Hyun-joo Lee ),( Gun-wook Kim ),( Hyun-chang Ko ),( Byung-soo Kim ),( Moon-bum Kim ),( Hoon-soo K 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.1
Malignant mixed tumor (MMT) is a rare malignant tumor originated from sweat gland cells. As MMT tends to recur after inadequate excision, an early wide excision with a broad margin thought that the most optimal treatment. A 78-year-old man presented with a skin-colored nodule on the right 2nd metacarpo-phalangeal joint with duration of three years. The nodule had been excised 3 times in other hospital before visiting us. However, lesion had recurred within the incision line. Histopathologic examination showed chondroid stroma with cords of cells forming glandular structures with increased mitotic activity and cellular atypia. Mohs microscopic surgery (MMS) was performed under the diagnosis of MMT. After two stages of MMS, a tumor-free plane was achieved with a 6x5 cm defect and tendon was preserved. The patient was transferred to plastic surgery department and the defect was reconstructed using skin graft. A 10 month follow-up revealed no local recurrence or metastasis. MMT tends to show unclear clinical margin, moreover hand is hard to secure sufficient margin. The aims of MMS are to preserve normal tissue and completely remove tumor, MMS could be a good treatment option for MMT of the hand that needs maximal tissue preservation. And the distinctive histology of MMT leads itself well to MMS to achieve complete tumor extirpation. So, we herein report a case of MMT of the skin on the hand dorsum treated with MMS.
미소 초기 응력 증분을 이용한 경계요소법의 탄소성 문제 해석
이수룡 ( Soo-lyong Lee ) 한국고등직업교육학회 2003 한국고등직업교육학회논문집 Vol.4 No.4
The Boundary Element Method(BEM) is a technique which offers important advantage over "domain" type problem such as FEM and FDM. Lately, in nonlinear problems like elasto-plastic, the method to divide the region in expectation of plastic deformation and to add the unknown nodal displacements of this region into the unknown of boundary integral equations was suggested. In this paper, the initial stress method was used to establish the formulation of Boundary Element Method on elasto-plastic problem. And to prove the appropriateness of this method, rectangular plate having a circular hole was analyzed and compared with the result of FEM.