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      • KCI등재

        비응축성 기체 존재 시 수직관 외벽에서의 응축 열전달계수 상관식 개발

        장영준(Yeong-Jun Jang),최동재(Dong-Jae Choi),김신(Sin Kim),정동욱(Dong Wook Jerng),이연건(Yeon-Gun Lee) 대한기계학회 2018 大韓機械學會論文集B Vol.42 No.3

        본 연구에서는 비응축성 기체(공기)가 존재할 때, 10 mm의 직경을 갖는 수직 튜브 외벽에서의 응축 열전달계수를 측정하였다. 압력 2~5 bar, 공기 질량분율 10~75 %의 범위에서 실험을 수행하였다. 응축튜브 직경의 차이가 열전달계수에 미치는 영향을 평가하기 위해 측정 결과를 외경 40 mm의 응축튜브로부터 얻은 Lee의 실험 결과와 비교하였다. 본 연구의 측정결과와 Lee, 그리고 Dehbi의 실험결과를 이용하여 전열관의 직경에 의한 영향을 고려할 수 있는 실험적 상관식을 제안하였다. 제안된 상관식의 검증을 위해 Kawakubo의 실험결과와 예측값을 비교하였고, 평균 표준편차는 약 27 %로 나타났다. In this study, condensation heat transfer coefficients are measured in the presence of noncondensable gas (i.e., air) on a vertical tube with a 10-mm outer diameter. Experiments are conducted at pressures ranging from 2 to 5 bar and an air-mass fraction from 10 to 75 %. The experimental results are compared to the heat transfer coefficients obtained on a 40-mm O.D. tube, researched by Lee et al. Using the consolidated data from this study and Lee"s and Dehbi"s tests, a new empirical correlation for the condensation heat transfer coefficient of an air-steam mixture is developed. The proposed correlation is assessed against Kawakubo"s experimental results, and the mean standard deviation is ~27 %.

      • 잎담배 생산농가의 경작규모별 곁순방제 소요노동력 조사

        최상진,김영신,이학수,석영선 충북대학교 연초연구소 2004 煙草硏究 Vol.19 No.-

        This study was carried out to decect efficient method of sucker control classifed by cultivation hectarage per farm in 57 farms selected in the main producing districts of flue-cured and burley tobacco. In topping, it was no difference of working hours by cultivation hectarage per farm in flue-cured and burley tobacco. Suckering was the best in working hours among working type, and the more cultivation hectarage per farm was small, the more working hours of topping, suckering and application of suckercide was increased. Application of system suckercide shows a decrease as compared with application of contact suckercide but the decrease of working hours in application of contact suckercide by cultivation hectarage per farm was larger than in system suckercide. 경작면적별 효율적인 곁순억제방법을 알아보고자 황색종 및 버어리종 주산지에서 57개 경작농가를 선정하여 조사한 결과를 요약하면 다음과 같다. 1. 적심작업의 경우 황색종과 버어리종 모두 경작면적에 의한 노력소요량의 차이는 없었다. 2. 곁순제거작업은 다른 작업에 비해 노력소요량이 가장 많았고, 경작면적이 작을수록 노력소요량이 증가하였다. 3. 황색종과 버어리종 모두 침투성 곁순억제살포작업에 비해 접촉성 약제살포작업에서 노력소요량이 많았으나 경작면적이 큰 경우 접촉성 약제 살포작업 노력소요량 감소폭이 침투성 곁순억제제 살포작업에 대한 노력소요량 감소폭보다 컸다. 4. 각 작업에 대하여 농가간 최저 및 최고 노력소요량 차이가 큰 것으로 나타나 조사방법과 시기를 보완하여 보다 체계적이고 세밀한 조사가 추가적으로 이루어져야 할 필요가 있다.

      • Rotary type과 linear type 자동흡연 장치에 따른 담배연기 중 타르, 니코틴 및 일산화탄소의 함량 비교

        정재훈,김영신,임흥빈,석영선,신주식,이학수 충북대학교 연초연구소 2004 煙草硏究 Vol.19 No.-

        본 실험은 type별 흡연 장치의 담배 주류연 포집에 대한 차이를 비교하고자 주류연 중 일반적인 다량의 성분을 측정하였다. 1. 니코틴 함량은 대체로 linear-type 흡연 장치에서 높은 경향 이였으나 유의한 차이는 없었다. 2. 수분 함량은 두 가지 type 간에 유의한 차이는 없었다. 3. tar 함량은 저 농도에서 linear-type 보다 otary-type 흡연 장치가 높은 경향 이였으나 유의한 차이는 없었다. 4. 일산화탄소는 rotary-type과 linear-type 모두 유의한 차이는 없었다. 본 실험결과 ISO 표준 흡연 조건에서 담배 주류연의 tar, 니코틴, 일산화탄소 함량의 측정은 흡연 장치의 type별 통계적으로 유의한 차이는 없는 것으로 판단된다. This study was conducted to compare rotary-type with linear-type automatic smoking machine referred to ISO 3308 in the determination of tar, nicotine and CO in cigarette smoke. Sample were used with 4 kinds of domestic branded cigarettes(tar ; 1, 3, 6, 10 mg/cig) and CORESTA Monitor 4 cigarettes(tar ; 14 mg/cig). Tar and nicotine contents were analysed by gas-chromatograph methods in accordance with ISO 4387 and 10315-1. Determination of carbon monoxide in the vapour phase of cigarette smoke was meaured by NDIR method in ISO 8454. Sample preparation were performed in conditioning room at 22℃, 60 % for 48 hours according to ISO 3402. There was no significant difference between two smoking machine from 1 mg/cig to 14 mg/cig tar cigarettes, but, the contents of three components measured by rotary type showed higher tendency than those by linear type in the case of hight tar cigarettes. The results were the opposite in low tar cigarettes.

      • 車體構造解析硏究

        김지홍,김천욱,이신영 연세대학교 산업기술연구소 1988 논문집 Vol.20 No.1

        An analysis on the load-bearing capacity of floor frame and body structure is investigated by the three dimensional rigid frame analysis. The load-bearing capacity of the body structure is estimated on the basis of comparison to the floor-frame-only structure. The location and magnitude of the maximum displacement are also determined and show good agreement with those of a previous study.In the present study the load-bearing capacity of the floor frame of van-type structures is about 80 percent of the total loadings.

      • Newly Synthesized Phosphodiesterase 4 (PDE4) Inhibitor, DWP205505, Inhibits TNF-α Secretion and mRNA Expression

        Lee, Suk-Kyeong,Lee, Sun-A,Byun, Hye-sin,Cho, Mi-La,Kim, Wan-Uk,Park, Sung-Hwan,Cho, Chul-Soo,Joo, Yeong-Shil,Lee, Shin-Seok,Yoo, Eun-Sook,Son, Ho-Jung,Kim, Ho-Youn THE CATHOLIC UNIVERSITY OF KOREA 2000 Bulletin of The Catholic Research Institutes of Me Vol.28 No.-

        The therapeutic potential of phosphodiesterase 4 (PDE4) inhibitors in inflammatory diseases including some autoimmune diseases has been explored recently with some hopeful results. These PDE4 inhibitors are thought to show their anti-inflammatory effect by down-regulating tumor necrosis factor-α (TNF -α) production in lymphocytes and macrophages. A high concentration of TNF -α have been found in rheumatoid arthritis (RA) synovium and reducing TNF -α using biological agents was proven to be an effective RA treatment. To test the possibility of using PDE4 inhibitors for RA treatment, the effects of a newly synthesized PDE4 inhibitor, DWP205505, on TNF -α and IL-10 production was tested in cells isolated from normal peripheral blood and rheumatoid arthritis synovial fluid. Cytokine production was assayed at the protein level by sandwich enzyme-linked immunosorbent assay (ELISA) and at the mRNA expression level by semi-quantitative RT-PCR. Another PDE4 inhibitor, RP73401, was used for comparison. DWP205505 and RP73401 had no harmful effect on cell viability up to 10 μM concentration during the 24 hour culture period. DWP205505 as well as RP73401 significantly reduced TNF -α secretion from both unstimulated and lipopolysaccharide (LPS)-stimulated perpheral blood mononuclear cells (PBMC) and synovial fluid mononuclear cells (SFMC). The effect of DWP205505 or RP73401 treatment on the mRNA expression of TNF -α was also studied in LPS-stimulated PBMC and SFMC. TNF -α mRNA expression was increased by LPS stimulation and both of the PDE4 inhibitors suppressed TNF -α mRNA expression. For interleukin-10 (IL-10), a little different results were obtained from PBMC and SFMC; IL-10 secretion was unaffected by LPS stimulation and only minimally affected by both of the PDE4 inhibitors in PBMC. In unstimulated SFMC, DWP205505 and RP73401 slightly enhanced IL-10 secretion, while they reduced IL-10 secretion from LPS-stimulated SFMC where IL-10 secretion was a lot higher than unstimulated SFMC. These results suggest that the newly synthesized PDE4 inhibitor DWP205505 may have anti-rheumatioid arthritis activity. (Journal of Microbiology and Biotechnology 9(1):106-112, 1999)

      • KCI등재SCOPUS

        백서 난소에서 세포고사 유전자 Bok의 발현

        이여일 ( Lee Yeo Il ),신현우 ( Sin Hyeon U ),이진 ( Lee Jin ),김미영 ( Kim Mi Yeong ),전상영 ( Jeon Sang Yeong ) 대한산부인과학회 2003 Obstetrics & Gynecology Science Vol.46 No.5

        Objective : Bok, Bcl-2-related ovarian killer, is a proapoptotic Bcl-2 family protein identified in the ovary based on its dimerization with the antiapoptotic protein Mcl-1. The present study examined the hormonal regulation and localization of Bok messenger RNA levels in the rat ovary during the follicle development. Methods : We used the female rats of SD strain. Bok mRNA levels in the ovary were determined by Northern blot analysis. In situ hybridization were performed to determine the specific ovarian cell type expressing Bok mRNA. Results : Northern blot analysis of ovaries obtained from immature rats revealed increasing levels of Bok mRNA during postnatal development. The major cell types expressing Bok mRNA were the granulosa cells of preantral and atretic follicles. Treatment of immature rats with diethylstilbestrol (DEX) for 24-48 h increased ovarian Bok mRNA levels. Bok mRNA was remained the same levels in rats removed DES for 24-48 h to induce apoptosis. High signals of Bok mRNA after DES treatment were detected in granulosa cells of early antral follicles. Treatment of immature rats with pregnant mare`s serum gonadotropin (PMSG) for 12h increased markedly ovarian Bok mRNA expression which was detected mainly in preantral and atretic follicles. Interestingly, low levels of Bok mRNA were also expressed in granulosa cells of preovulatory follicles. Treatment of PMSG-primed rats with human chorionic gonadotropin (hCG) stimulated strongly ovarian Bok mRNA expression at 6-9 h. At that time, Bok mRNA was expressed in granulosa cells of atretic and small growing follicles. In adult estrus cyclic ovaries, Bok gene expression was higher on proestrus and estrus than metaestrus and diestrus. Moreover, the highly increased expression of Bok mRNA was found in rat ovaries at 48 h after hypophysectomy.

      • KCI등재

        FISH법을 이용한 낙동강 상,중,하류의 세균군집 구조 분석

        이영옥 ( Lee Yeong Og ),박지은 ( Park Ji Eun ),신승필 ( Sin Seung Pil ),안영희 ( An Yeong Hui ) 한국물환경학회 2003 한국물환경학회지 Vol.19 No.3

        For conducting the comparative analysis of the eubacterial community structure including nitrifying bacteria at 8 sampling sites throughout the N마-Dong River, FISH(fluorescence in situ hybridization) method was employed. The total ratio of each determined eubacterial group such as α·β·γ-subclasses protebacteria and Cytophaga-Flavobacterium(CF) group to total counts stained by DAPI at each site varied 9.3∼42.5% with the highest value at uppermost part. And each ratio of determined eubacterial groups reached mostly under 10% except those of CF group(23%) at uppermost part. Futhermore, compared to lower part, upper part represented higher proportions of γ-subclass proteobacteria comprised in most of fast growing bacteria on degradable organics. Also the variations of ammonia-oxidizing bacteria ranged from 2.7×10⁴to 18.3×10⁴ cells/㎖ with the lowest value in lower part and the highest value in mid part whereas those of nitrite-oxidizing bacteria varied 5.2∼7.7×10⁴cell/㎖ without noticeable differences throughout the sites. Additionally, the ratio of nitrifying bacteria to total counts ranged from 1.3% to 13.6?%, regardless of those of ammonia/nitrite-oxidizing bacteria. Overall, it implies that the upper part of Nak-Dong River represented comparatively better degradabilities of organic materials than their Lower part except at one site in upper part passed An-Dong City. By the contrast, the other part of Nak-Dong River, especially after merging the Gum-Ho River revealed lower detectability of FISH resulted from their cellular activity. So it could be said that the lower part of Nak-Dong River might be a ecosystem of which physico-chemical environment may have inhibited the activities of bacteria functioned as decomposer of organic matter.

      • KCI등재SCOPUS

        30대 젊은 여성에서 발생한 자궁내막암 6예의 임상 병리학적 고찰

        신수경 ( Sin Su Gyeong ),이풍구 ( Lee Pung Gu ),신정규 ( Sin Jeong Gyu ),최원준 ( Choe Won Jun ),이순애 ( Lee Sun Ae ),이종학 ( Lee Jong Hag ),백원영 ( Baeg Won Yeong ) 대한산부인과학회 2003 Obstetrics & Gynecology Science Vol.46 No.10

        Objective : This study was performed to evaluate the clinical characteristics, histopathology and prognosis of endometrial cancer under 40 years of age. Methods : This retrospective study was based on medical records including pathologic reports of 6 wome

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