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      • KCI등재

        신경망분석을 이용한 축구경기 승,패 예측모형 개발 -2006독일월드컵 대회를 중심으로-

        김주학 ( Joo Hak Kim ),노갑택 ( Gap Taik Ro ),박종성 ( Jong Sung Park ),이원희 ( Won Hi Lee ) 한국스포츠정책과학원(구 한국스포츠개발원) 2007 체육과학연구 Vol.18 No.4

        본 연구는 축구 경기 기록자료를 활용하여 축구경기의 승·패를 예측할 수 있는 모형을 개발하는 데 있다. 활용된 경기기록 자료는 2006년 독일 월드컵대회에 나타난 축구경기 전체 64경기의 FIFA TSG공식자료와 M대학교 경기분석 프로그램을 활용하여 산출된 경기기록 자료를 사용하였다. 연구기법으로는 최근에 예측연구에 많이 활용되고 있는 신경망 분석을 이용하여 예측율을 확인 하였으며, 예측율은 2개의 예측모형으로 분류하여 결과를 산출하였다. 구체적인 내용 및 방법은 다음과 같다. 2006년 독일월드컵에 나타난 기록 관련 요인 중 경기 내적요인을 중심으로 축구 경기의 승·패와 관련한 요인을 탐색하고 2006년 독일월드컵 전 경기에 대한 비디오녹화를 실시하였으며, 녹화된 비디오를 통하여 기록요인에 대하여 실시간 축구 경기분석 프로그램을 활용, 승·패와 관련한 기록요인을 점수화하였다. 점수화된 기록요인은 점유율, 성공률 관련 등 여러 가지 요인이 있었으나 실제 경기에서 예측을 할 수 있는 요인을 전문가와 회의를 통하여 선정하고 선정된 요인을 바탕으로 신경망 분석방법을 이용하여 축구경기 승·패 예측 모형을 개발하여 예측율을 확인하였다. 본 연구의 결과는 다음과 같다. 첫째, 전문가회의를 통하여 기록화 할 수 있는 기록자료 요인을 중심으로 2006년 독일월드컵 전체 경기에 대하여 축구 경기분석 프로그램을 통하여 점수화하여 실제 다양한 요인이 내재된 경기에 대하여서도 내용분류를 통하여 점수화할 수 있음을 확인하였다. 둘째, 점수화된 경기 내적요인을 중심으로 신경망분석 방법을 통하여 축구경기에 대하여서도 승·패를 예측할 수 있음을 확인하였으며 타 종목에 대하여서도 실현 가능함을 확인할 수 있었다. 셋째, 축구경기의 승패에 대하여 87.5%의 예측율을 보임으로써 축구경기의 요인에 대한 중요도를 평가할 수 있는 연구의 기초를 확립하였다고 판단된다. This study was on purpose to investigate the various factors of soccer games into inner factors and classify performance factors objectively and scientifically using a soccer game analysis program and develop a model which can predict the result of the soccer games using the Neural NetWork Analysis that stands on the game graded record. The game recorded data was collected from the FIFA TSG official record and the data which was gained using a game analysis program. It has searched the factors related the game results which were focused on the game inner factors of the related factors in 2006 World cup games and recorded the whole games of 2006 World cup games, graded the recording factors related the win/lose using the video and the real time game analysis program with numbers. The graded recording factors with numbers were several; ball possession, completion, and so on. However, through the meeting with Neural NetWork Analysis, professionals prediction related factors which can predict in the real games were selected. And a soccer game win/lose prediction model was developed using the selected factors and Neural NetWork Analysis. It also was compared with the preceding researches in documents record studies. Followings are main results of this study; First, It was confirmed that it is available to grade the real factors in the games which include various factors through the professionals` meetings which implemented the analysis the 2006 Worldcup games and it was focused on the recording factors. Second, the graded recording inner-factors make it possible to predict the soccer game results using the Neural NetWork Analysis method. It was verified that it can be effective in other sports also. Third, the rate of predicting the soccer games` results was 87.5%. It is possible to understand this study contributes on the basis of the importancy of soccer game factors.

      • 검단산(경기도 하남시)의 거미상

        김주필(Joo Pil Kim),최한석(Han Seak Choi),이형민(Hyung Min Lee),이형진(Hyung Jeen Lee),이태후(Tae Hoo Lee),심주영(Ju Young Sim),조윤규(Yoon Kyu Jo),조원규(Won Kyu Jo),이준이(Joon Lee Lee) 한국거미연구소 2018 한국거미 Vol.34 No.2

        2018년 10월 2일부터 3일까지 경기도 하남시 소재 검단산을 주야로 한국거미연구회 회원 13명(김주필, 최한석, 이형민, 이형진, 심주영, 이태후, 조윤규, 조원규, 이준이, 이현동, 윤혜원, 이광섭, 김형주)이 채집한 결과 22과 43속 56종이 채집되어 이에 보고 발표하는 바이다. From October 2 to 3 in 2018. Koran Arachnological Study members investigated the Spiders in the whole area Gyeonggi-do Hanam-si, and reported 22 Families, 43 Genus 56 Species of spiders. The collected spiders are placed (stored) in the Joo-Pil Spider museum.

      • 화야산(경기도 가평군)의 거미상

        김주필(Joo Pil Kim),최한석(Han Seak Choi),이형민(Hyung Min Lee),이형진(Hyung Jeen Lee),이태후(Tae Hoo Lee),심주영(Ju Young Sim),조윤규(Yoon Kyu Jo),조원규(Won Kyu Jo),이준이(Joon Lee Lee) 한국거미연구소 2018 한국거미 Vol.34 No.2

        2018년 10월 13일부터 14일까지 경기도 가평군 소재 화야산을 주야로 한국거미연구회 회원 13명(김주필, 최한석, 이형민, 이형진, 심주영, 이태후, 조윤규, 조원규, 이준이, 이현동, 윤혜원, 이광섭, 김형주)이 채집한 결과 18과 41속 48종이 채집되어 이에 보고 발표하는 바이다. From October 13 to 14 in 2018. Koran Arachnological Study members investigated the Spiders in the whole area Gyeonggi-do Gapyeong-gun, and reported 18 Families 41 Genus 48 Species of spiders. The collected spiders are placed (stored) in the Joo-Pil Spider museum.

      • KCI등재후보

        알레르기 환자에서 한방 이외의 대체 요법의 사용 현황에 대한 다기관 조사

        이현정 ( Hyun Jung Lee ),이재현 ( Jae Hyun Lee ),이용원 ( Yong Won Lee ),김철우 ( Cheol Woo Kim ),동헌종 ( Hun Jong Dhong ),박해심 ( Hae Sim Park ),조영주 ( Young Joo Cho ),조진희 ( Jin Hee Cho ),조상헌 ( Sang Heon Cho ),편복양 ( 대한내과학회 2011 대한내과학회지 Vol.80 No.1

        Background/Aims: The use of unproven complementary/alternative medicine (CAM) to treat allergies is popular in Korea. We conducted a multicenter survey of the current use of CAM other than herbal medication in Korean allergy patients. Methods: This study enrolled 510 adults with allergic diseases, including asthma, allergic rhinitis, atopic dermatitis, and chronic urticaria, from ten hospitals. They underwent a structured questionnaire interview and clinical assessment of the prevalence, motivation, costs, and subjective assessment of CAM. Results: Of the patients, 16.7% used at least one type of CAM to treat their allergic diseases. Common types of CAM were diet (48.6%), aroma therapy (23.8%), massage (14.3%), breathing exercises (7.6%), baths (5.7%), and mind control (5.7%). The therapeutic effects of CAM included improved in patients using mind control (50%), diet (50%), breathing exercises (75%), and baths (33.3%), but worse in patients using aroma therapy (28%), and massage (26.7%). About 36.4% of the patients used CAM more than four times per year, and the average cost per CAM user was 370,000 won/year. The main reason for trying CAM was `hope to improve my constitution`. Conclusions: CAM is used widely for treating allergic diseases in Korea. Detailed knowledge of CAM and patient education are important. Further studies of the clinical efficacy of CAM are needed. (Korean J Med 2011;80:68-77)

      • SCOPUSKCI등재

        Genetic Characterization of Haemagglutinin 1 Domain of Influenza B Viruses Isolated in Korea during $1988{\sim}1999$

        Shin, Gu-Choul,Na, Byoung-Kuk,Lee, Joo-Yeon,Ahn, Jung-Bae,Park, Jong-Won,Lee, Jin-Soo,Kim, Jee-Hee,Kim, Woo-Joo,Kang, Chun The Korean Society for Microbiology 2003 Journal of Bacteriology and Virology Vol.33 No.4

        Although Korean influenza virus isolates have been genetically associated with the vaccine strains of the corresponding year, influenza B viruses have prevailed almost every year in Korea during the past decades. We have 'analyzed the genetic characteristics and evolutionary patterns of the haemagglutinin (HA) 1 domains of influenza B viruses isolated during 1988-1999 using direct RT-PCR and sequencing. Phylogenetic analysis of influenza B viruses isolated in Korea indicated that antigenically and genetically distinguishable strains of the lineage II and lineage III variants had been cocirculated. Variants prevailed in early 1990s are represented in 1996/97 and 1998/99 and some different variants have been co circulated geographically and prevailed concurrently in Korea. All HA1s of Korean isolates have amino acid substitutions mainly in the region between position 124 and 310, which was previously proposed an immunodominant region. Insertion-deletion patterns of the HA gene revealed that Korean influenza B viruses were evolved from Lee40 with different manner between lineage II and III viruses. Lineage III viruses were also divided into two groups as conserved group and inserted group, in relation to Lee40. But lineage II viruses had evolved with directional pattern. Antigenic index proposed that influenza B isolates prevailed since 1996/97 seasons might had emerged from the antigenic variants of a Seo1697-like virus and that new variants might appear from the lineage II viruses resulting in persistent prevalence in Korea.

      • Senescent T Cells Predict the Development of Hyperglycemia in Humans

        Lee, Yong-ho,Kim, So Ra,Han, Dai Hoon,Yu, Hee Tae,Han, Yoon Dae,Kim, Jin Hee,Kim, Soo Hyun,Lee, Chan Joo,Min, Byoung-Hoon,Kim, Dong-Hyun,Kim, Kyung Hwan,Cho, Jin Won,Lee, Won-Woo,Shin, Eui-Cheol,Park, American Diabetes Association 2019 Diabetes Vol.68 No.1

        <P>Senescent T cells have been implicated in chronic inflammatory and cardiovascular diseases. In this study, we explored the relationship between senescent T cells and glycemic status in a cohort of 805 participants by investigating the frequency of CD57<SUP>+</SUP> or CD28<SUP>null</SUP> senescent T cells in peripheral blood. Participants with normal glucose tolerance (NGT) with follow-up data (<I>N</I> = 149) were included to determine whether hyperglycemia (prediabetes or type 2 diabetes) developed during follow-up (mean 2.3 years). CD8<SUP>+</SUP>CD57<SUP>+</SUP> and CD8<SUP>+</SUP>CD28<SUP>null</SUP> T-cell frequencies were significantly higher in prediabetes and type 2 diabetes compared with NGT. Increased CD57<SUP>+</SUP> or CD28<SUP>null</SUP> cells in the CD8<SUP>+</SUP> T-cell subset were independently associated with hyperglycemia. Furthermore, among participants with baseline NGT, the frequency of CD8<SUP>+</SUP>CD57<SUP>+</SUP> T cells was an independent predictor of hyperglycemia development. Immunofluorescent analyses confirmed that CD8<SUP>+</SUP>CD57<SUP>+</SUP> T-cell infiltration was increased in visceral adipose tissue of patients with prediabetes or type 2 diabetes compared with those with NGT. Our data suggest that increased frequency of senescent CD8<SUP>+</SUP> T cells in the peripheral blood is associated with development of hyperglycemia.</P>

      • Repositioning disulfiram as a radiosensitizer against atypical teratoid/rhabdoid tumor

        Lee, Young Eun,Choi, Seung Ah,Kwack, Pil Ae,Kim, Hak Jae,Kim, Il Han,Wang, Kyu-Chang,Phi, Ji Hoon,Lee, Ji Yeoun,Chong, Sangjoon,Park, Sung-Hye,Park, Kyung Duk,Hwang, Do Won,Joo, Kyeung Min,Kim, Seung- Oxford University Press 2017 Neuro-oncology Vol.19 No.8

        <P>Conclusions. DSF and RT combination therapy has additive therapeutic effects on AT/RT by potentiating programmed cell death, including apoptosis and autophagy of AT/RT cells. We suggest that DSF can be applied as a radiosensitizer in AT/RT treatment.</P>

      • Self-Assembled Nanoconstructs Modified with Amplified Aptamers Inhibited Tumor Growth and Retinal Vascular Hyperpermeability via Vascular Endothelial Growth Factor Capturing

        Lee, Jihyun,Lee, Byung Joo,Lee, Yeong Mi,Park, Hansoo,Kim, Jeong Hun,Kim, Won Jong American Chemical Society 2017 Molecular pharmaceutics Vol.14 No.5

        <P>Here, nanoconstructs consisting of a DNA- amplified aptamer with a biocompatible polymer backbone for capturing target biomolecules are presented. First, the polymer-DNA nanoconstructs were prepared by hybridization of two complementary single-stranded DNAs that were each conjugated to a dextran polymer backbone. The designed polymer-DNA amplified aptamer nanoconstructs (PA-aNCs) were then prepared by utilizing polymer-DNA nanoconstructs conjugated with an aptamer (PA-NCs) using a rolling circle amplification reaction to amplify the aptamer. These PA-aNCs were successfully applied to alleviate tumor growth and vascular endothelial growth factor (VEGF)induced retinal vascular hyperpermeability in vivo through the highly effective capture of human VEGF as a target molecule. These PA-aNCs could be used as therapeutic agent for anti-VEGF therapy by efficiently capturing human VEGF.</P>

      • Triamcinolone-carbon nanotube conjugation inhibits inflammation of human arthritis synovial fibroblasts

        Lee, Yeon Kyung,Choi, Jin Kyeong,Kang, Youn Joo,Kim, Hye Won,Kim, Sang-Woo,Park, Chul-Kyu,Khang, Dongwoo,Kim, Sang-Hyun The Royal Society of Chemistry 2016 Journal of materials chemistry. B, Materials for b Vol.4 No.9

        <P>Repetitive intra-articular corticosteroid injections are inevitable for treating synovial inflammation in advanced arthritis. However, short- and long-term use of corticosteroids usually triggers serious side effects (<I>i.e.</I>, adrenal insufficiency, hyperglycemia, Cushing syndrome, osteoporosis, Charcot arthropathy,<I>etc.</I>). This study demonstrated that conjugation of a corticosteroid (triamcinolone) on polyethylene-glycol (PEG)-fabricated multi-walled carbon nanotubes enhances intracellular drug delivery<I>via</I>increased lysosome transport and ultimately suppresses the expression of major pro-inflammatory cytokines (<I>i.e.</I>, TNF-α, IL-1β, and IL-6) and matrix metalloproteinase-1 and -3 from fibroblast-like synoviocytes at a very low drug dose. Specifically, conjugation of triamcinolone and multi-walled carbon nanotubes inactivated nuclear factor-κB<I>via</I>inhibition of the phosphorylation of mitogen-activated protein kinases and the serine/threonine kinase Akt. In summary, low-dose triamcinolone conjugation with carbon nanotubes significantly inhibited the inflammatory response of fibroblast-like synoviocytes by achieving highly efficient intracellular trafficking and suggested a potential drug candidate for resolving side effects associated with conventional arthritis treatment.</P>

      • SCOPUSKCI등재

        토양에서 분리한 살충성 Bacillus thuringiensis의 모기와 누에 유충에 대한 독성효과 (II)

        Lee, Hyung-Hoan,Yoo, Bo-Rim,Kim, Young-Joo,Won, Nam-Hi,Kim, Hak-Chun The Microbiological Society of Korea 1993 미생물학회지 Vol.31 No.1

        Eight strains of Bacillus thuringiensis were isolated from soil in Korea and characterized. The isolates were named HL-24, HL-25, HL-33, HL-34, HL-35, HL-38, HL-39, HL-40. Strains HL-24 and HL-25 produced irregular parasporal crystals, HL-33 and HL-35 produced bipyramidal crystals, and others were round form in their cells. The biochemical characteristics of the eight isolates were only minor different in specific characteristics to the known serotypes of Bacillus thuringiensis. The HL-25, HL-33 and HL-34 strains showed resistances to cephalothin, colistin and penicillin G, and HL-39 and HL-40 strains were resistant to penicilin G. The strains of HL-24, HL-25, HL-33 and HL-34 were toxic to Bombyx mori lavae and HL-24, HL-25, HL-38, HL-39 and HL-40 strains killed Culex pipiens 3rd instar larvae. The HL-24 and H25 strains showed lethal activity against two kinds of the larvae, however lethality against mosquito larvae was low. Bacillus thuringiensis를 한국의 토양에서 분리하여 특성을 연구했다. 8균주를 분리하여 HL-24, HL-25, HL-33, HL-34, HL-35, HL-38, HL-39와 HL-40으로 명명했으며. HL-24와 HL-25는 부정형의 crystal를 가졌고, HL-33과 HL-35는 이중피라미드형, HL-34. HL-38, HL-39와 HL-40은 둥근형의 crystal를 가진 것을 위상차현미경으로 관찰했다. 분리균들의 생화학적인 특성은 이미 알려진 균주들과 유사했으나. 특이한 차이점을 가지고 있었다. HL-25, HL-33과 HL-34는 cephalothin, colistin과 penicillin G에 내성을, HL-33과 HL-35균주는 chloramphenicol에 내성을 HL-39와 HL-40은 penicillin G에 내성을 나타냈다. 균주HL-24, HL-25, HL-33과 HL-34는 누에 유충에 대한 치사성은 100.85.55. 및 70%를 각각 나타냈으며 HL-24, HL-25, HL-38, HL-39와 HL-40의 모기 유충에 대한 치사성은 10. 20. 100. 100 및 90%였다. HL-24와 HL-25균주는 누에와 모기 유충에 모두 치사성은 나타냈으나. 모기에는 살충효과가 10~20%로 매우 낮았다.

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