무증상 당뇨환자의 T 반사 변화

안규환,조용진,김상화,사은희,임용빈,김대성,정대수,박규현 대한신경과학회 1999 대한신경과학회지 Vol.17 No.5

치료 저항성 환청을 나타내는 만성 정신분열병 환자에서 측두두정부 반복 경두개자기자극의 효과

정경희,최충식,박진수,이규항,함웅,이승환,채정호 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.5

Objectives : It has been reported that repetitive transcranial magnetic stimulation (rTMS), which stimulate the focal region of brain may relieve auditory hallucination in patient with schizophrenia. This study was aimed to evaluate the effect of rTMS on left and right temporopahetal cortex in schizophrenic patients with treatment-resistant auditory hallucination. Methods : Twenty-six patients with chronic schizophrenia with treatment -resistant auditory hallucination were randomly a1-located to rTMS group on left and right temporoparietal head regions. The rTMS was applied to TP3/4 region by EEG 10-20 international system at 1 Hz for 20 minutes per day for 101reatment days. A Figure of eight TMS coil with a solid core was used for rTMS at 100% of individual motor threshold. Efficacy was evaluated with Auditory Hallucination Rating Scale (HRS), Positive and Negative Symptoms Scale (PANSS), Clinical Global Impression (CGI) Scale on 5 and 10 days of treatment. Results : Ten days administration of l-Hz rTMS to temporopahetal cortex significant improved frequency (p<0.001) and attentional salience (p=0.038) of auditory hallucination, Positive (p<0.001) and negative symptom (p=0.02), and CGI-impro-vement (p<0.001). There were no significant differences between right and left side stimulations. Conclusion : These results suggest that the low frequency rTMS on temporopahetal cortex may be useful in treating Schizo-phrenic patients with treatment-resistant auditory hallucination and it could be a useful novel treatment option.

Cyclosporin A에 의한 비만세포 고사(apoptosis)

노환중,장형준,조규섭,김유선,유영현,전경명 대한이비인후과학회 2001 대한이비인후과학회지 두경부외과학 Vol.44 No.12

만성 C형 간염 환자에서 페그인터페론 알파2a와 리바비린 병합 치료중 발생한 벨마비 1예

김일환,장제혁,유충헌,최규남,고정해,김윤정,서광원,김지현,박성재,박은택,이연재,이상혁,설상영 인제대학교 2008 仁濟醫學 Vol.29 No.-

페그인터페론과 리바비린 병합요법은 만성 C형 간염의 일차 치료법이다. 저자들은 만성 C형 간염 환자에서 페그인터페론 과 리바비린 병합 요법 중에 발생한 벨마비 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. 환자는 5년 전부터 만성 C형 간염을 앓아온 48세 남자이며, PEG-IFN α-2a 135μgm 피하주사 주1회와 하루 1200㎎의 리바비린을 투여하였다. 치료시작 후 9개월째 환자는 오른쪽 안면의 근력약화를 호소하였으며 벨마비로 진단되었다. 페그인터페론과 리바비린 병합요법을 지속하면서 관찰하였다. 환자의 벨마비는 페그인터페론 치료를 중단하지 않았음에도 3개월후 증상이 회복되고 이후 벨마비 재발 없이 현재 경과관찰 중이다. 만성 C형 간염에서 페그인터페론과 리바비린 병합 요법시 벨마비의 발생 가능성을 염두에 두어야 하겠다. A Case of Bell's Palsy Associated with Combination Therapy of Pegylated Interferon Alfa-2a (PEG-IFN) and Ribavirin for Chronic Hepatitis C Virus Infection Pegylated interferon alfa(PEG-IFN α) and ribavirin therapy is the first line treatment for chronic hepatitis C. Mild complications of the therapy are common, but more serious complications are rare. We report here a case of Bell's palsy that occurred in a patient with chronic hepatitis C virus infection during combination therapy of PEG-IFN α-2a and ribavirin. The patient was 49-year-old man with chronic hepatitis C (genotype 1b) for 8 years. He had compensated liver cirrhosis with splenomegaly. Therapy with PEG-IFN α- 2a 135mcg/week and ribavirin 1200mg/day was initiated. After 9 months of the therapy, the patient showed a loss of muscular tone on the right side of his face. A diagnosis of Bell's palsy was made. The Bell's palsy resolved over 3 months despite continuation of the combination therapy.

유도 어깨로메치기의 운동학적 특성분석

김의환,김규수,김성섭,박중제 龍仁大學校 武道硏究所 2001 武道硏究所誌 Vol.12 No.1

The purpose of this study was to analyze the kinematic variables when performing Kata-guruma in judo. Yong-In University judo demonstration squad was filmed (30frames/sec.) on 16mm video camera on performing of Kata-guruma in judo. Kinematic variables analyzed here include time, angle and center of gravity. The mean values and the standard deviations for each variables were obtained and used as basic factors for examining characteristic of Kata-Guruma motion. The result of this analysis are ads following. 1) Angle variables From Kumikata to 1st stage in KP, the angle of right elbow in Kata-Guruma was decreased, to 2nd phase and air phase were increased slightly. Lefe elbow angle of Tsukuri motion was decreased from 1st stage in KP to air motion were increased. Kuzushi of right shoulder angle was decreased, Tsukuri of right shoulder was increased, air posture in Kake phase was increased, Kuzushi of left shoulder angle was increased and Tsukuri of left shoulder angle was decreased continually. Both angle of hips were decreased in 1st stage in KP phase. From 2nd stage in KP to air motion were increased slightly. Both angle of Knees were decreased in 1st Kake phase, from 2nd stage KP to air motion were increased again. Left arm obstructs the center of gravity of opposite, extends in order to set the body, and flexes in other to fling the body of the shoulder. Right arm was flexed on order to let the arm in between legs, and flexes on Kake motion and was extended in other to fling the body of the shoulder. According to result of angle variables, deflection of the subject A was of small quantity, and both subject A and B were fixed in view of subject B.

팔굽관절에서 측정방법에 따른 고유수용성감각 차이

이정아,김덕화,신화경,최규환,권오윤 한국전문물리치료학회 2003 한국전문물리치료학회지 Vol.10 No.3

신경회로망 자기동조 PID 제어기를 이용한 전력계통 안정화에 관한 연구

정형환,김상효,이정필,정문규 동아대학교 공과대학부설 생산기술연구소 1998 生産技術硏究所硏究論文集 Vol.3 No.2

This paper applied the neural network self-tuning PID controller to its linearized one-machine infinite bus for improvement in the power system stabilization. It ia tried to regulate the optimum parameters of the PID Controller using the learning algorithm of error back propagation. The simulation results show that the proposed control technique is decidedly superior to the conventional ones in dynamic responses about various disturbances arising in the power system.

축 수직단면 형상정의에 의한 대형 스크류의 가공시 공구간섭검사

이원규,안중환,박규열 韓國工作機械學會 2000 한국생산제조학회지 Vol.9 No.3

In machining screws which are important members in mono pumps or progressive cavity pumps, CNC turning center with 3 axes is usually used. This soil of screw machining requires large amount of CL data points and rotational tools are used in machining. When working out the CL data points, consideration of possible tool interference is important in order to avoid undercut. This paper describes the checking methods of tool interference that could occur in the screw machining on the CNC turning center. First of all a specific shape of a screw cross-section that could commonly be applied to all screws was chosen, and then possible tool interference associated with that shape was identified. Checking method was mathematically developed and verified. This checking method will be utilized in the CAM system developed by the authors for screw machining on the 3-axis CNC turning center.

안와를 침범한 상악동 악성종양에서 안구 보존을 위한 내시경의 역할

조규섭,노환중 부산대학교 병원 암연구소 2008 부산대병원학술지 Vol.- No.24

Background and Objectives: The periorbita has been regarded as the crucial structure in decision of orbital exenteration in the patients with paranasal malignancies. The mass beyond the thickened periorbita on T2-weighted images was considered to be a positive finding of orbital invasion. The purpose of this study is to evaluate the oncological safety of endoscopic removal of infiltrated tumor onto the periorbita but not transgress into orbital fat. Patients and Methods: Five patients of advanced maxillary cancer, showing bony orbital wall destruction and infiltration onto the periorbita but not transgress into orbital fat, underwent partial or total maxillectomy. Preoperative Cl and MRI were performed in all cases and compared with intraoperative findings. The successful dissection between tumors and periorbita using bipolar nasal coagulation forceps and tumor forcep was performed under endoscopy. Results: The mean age was 54.4 (41-74) years. All tumors of five patients originated from maxillary sinus and extended to involve multiple different subsites according to AJCC (2002, 6^(th) ed.) Histopathology included four squamous cell carcinomas and one adenoid cystic carcinoma. Follow-up ranged from 30 to 121 months (mean 53.6 months). All cases showed no local recurrence on the periobita after endoscopic removal. One patient had local recurrence in the pterygopalatine fossa and the other had in the neck. Conclusion: Endoscopic removal of infiltrated tumor onto the periorbita using microdebrider, bipolar nasal coagulation forceps and tumor forceps can be oncologically safe technique in advanced maxillary cancer infiltrated onto the periorbita but not invaded into orbital fat.

초기 성공적인 심폐소생술후 혈청 Interleukin-6 농도의 발현양상

박규남,박승현,황두영,김형국,이환,최경호,이원재,정욱성,김학주,김세경 大韓應急醫學會 1998 대한응급의학회지 Vol.9 No.4

Objective : To investgate patterns of serial serum interleukin-6(IL-6) concentrations after initial successful cardiopulmonary resuscitation, and to access differences in serum IL-6 concentrations in patients with Cerebral Performance Category(CPC, 1-2) and CPC(3-5) at the 5th day after cardiacpulmonary resuscitation(CPR). Methods : We studied prospectively 12 patients with spontaneous circulation after cardiopulmonary resuscitation. Venous blood samples were taken 2, 4, 12, 24, 48 and 72 hours after restoration of spontaneous circulation to measure serum IL-6 levels by the enzyme-linked immunosorbent assay. Results : Serum IL-6 concentrations in the severe neurolgically disabled group(CPC, 3-5) were significantly increased at 2, 24 and 48 hours after restoration of spontaneous circulation compared with the less neurolgically disabled group. Also, serum IL-6 concentrations in the severe neurolgic disabled group showed dual peak at 4 and 24 hours. Conclusion : Our study demonstrates significant increase of serum IL-6 in patients with CPC(3-5) after successful cardiopulmonary resuscitation and the significant correlation between early increase of serum IL-6 and poor neurologic outcome. It suggests that early increase of serum IL-6 can be used as a prognostic marker after successful cardiopulmonary resuscitation.