성과 에이즈에 관한 보건교육 방법별 효과 측정

권관우,이경무,김훈수,김정순,정경균 韓國保健敎育.健康增進學會 2000 보건교육건강증진학회지 Vol.17 No.2

The objective of this study is to find the most effective educational method on Sex and AIDS/HIV among young people in Korea. The number of people with HIV amounts to 1,224 as of Sep. 2000, and is increasing continuously, especially among young people(National Institute of Health, 2000). In setting up the policy of health education on Sex and AIDS, the criteria should be the effectiveness. By two-stage cluster sampling, 4,713 students were selected from among the 19,093 students from 44 middle and high schools and divided into three groups and taken the education with three different methods(〈lecture with slides show〉, 〈lecture without any material〉 and 〈lecture through broadcasting system〉) by the same lecturer with the same contents for about 50 minutes. To compare the effects of education by methods, the tests on the AIDS knowledge, AIDS attitude on AIDS and Sexuality attitudes with self-administered questionnaire were implemented three times, that is, 'before', 'right after' and '2 weeks later' of the education. As to the decrees of change of AIDS knowledge, AIDS attitudes, Sexuality attitudes and subjective evaluation of the education, 〈lecture with slides show〉 was the most effective, 〈lecture without any material〉 was the second and 〈lecture through broadcasting system〉 was the least effective, respectively. In the cost-effectiveness analysis using the results of this study, 〈lecture with slides show〉 turned out to be the most effective, and 〈lecture through broadcasting system〉 was the second and 〈lecture without any material〉 was least effective. From these results, it is suggested that 〈lecture with slides show〉 is more effective health educational methods on Sex and AIDS than 〈lecture without any material〉 or 〈lecture through broadcasting system〉.

중고등학생의 에이즈 豫防敎育을 통한 에이즈 知識과 性意識 變化에 關한 硏究

권관우,이경무,김정순 韓國學校保健學會 1999 韓國學校保健學會誌 Vol.12 No.1

AIDS is worldwide problem. It has threatens societies and is potentially a big problem among youth. UNAIDS has warned that collective global responses are necessary; with half of the newly infected being children and young people in 1998, educating youth below age 24 is essential. Because of both their unexpected, strong sexual activities and an easjer tendency to change their behavior than adults, UNAIDS emphasizes the importance of prevention education leer youth. In Korea, 4 cases of HIV infection have officially been reported among high school students. Considering the potential seriousness of HIV inflection among youth, the Korean Anti- AIDS Federation (KAAF) began an education programme for Korean youth (middle & high school pupils) as one intervention method in 1993. The purpose of this study is to evaluate the impact of the education programs performed and to develop a better programme. The intervention method used in this study was mainly a lecture in a big or small auditorium or through broadcasting systems using audio-visual teaching aids. The period of this survey was from Nov. 10 to Dec. 26. in 1998. The subjects surveyed were 792 pupils who were sampled from 12 different middle and high schools in Seoul by a two-stage cluster sampling. Self recording the structured questionnaire was used far data collection. Data were analyzed by using a paired t-test to compare the knowledge difference before and after the interrention method. A chi-square test to compare the consciousness difference between pre-post-education results was used, and an ANOVA was used to compare the knowledge difference among the selected groups. Major results of this study are summarized as follows: (1) AIDS knowledge significantly changed after AIDS prevention education. (2) The direct lecture in a big or small auditorium is more effective than an indirect lecture through a broadcasting system or through audio-visual teaching aids. (3) Those who had not seen obscene materials (e.g. pornography films, magazines etc.) acquired much more knowledge than others after AIDS prevention education. (4) Those who had no girlfriend/or boyfriend acquired much more knowledge than the others after AIDS prevention education. (5) As to the attitudes toward chastity, more girls than boys and students who had not seen obscene materials rather than those who already had were liable to support the state ment: "all should remain chase" and their consciousness on "being chaste" changed much more than that of others after intervention. (6) As to the individual evaluation of lectures, 23.1% shows "very good" , 44.1% "good" , 26.9% "normal"'-'thus, the positive evaluation was to 94.2%. The negative response was 5.8%. (7) As to the desire fur AIDS education sponsored by KAAF in the future, more than몫90.5% showed a positive reaction. (8) As to the educators in future education methods, pupils wanted lecturers from outside their schood. (9) Students from vocational high schools have seen obscene materials much more than other groups and the percentage of these who had a girlfriend/or boyfriend was higher than that of the ethers as wello. (10) 90% of those who watched obscene materials responded that they experienced these materials while at middle school and 100% before reaching the second grade of high school. (11) The number of boys who have experienced obscene materials is twice as many as that of girls. (12) The percentage of boys who have a girlfriend is much higher than the percentage of girls who have a boyfriend. (13) Among those who have friends of the opposite sex, 11.1% say that they hare had sexual contact and 20.8% hare experienced kissing and caressing.

마이크로 로봇을 위한 비젼 시스템 개발

石尙祐,林廣洙,李炅武 弘益大學校 科學技術硏究所 2001 科學技術硏究論文集 Vol.12 No.-

In this research, we have developed a new navigation scheme using computer vision technology. A line feature tacking-based scheme is developed in which the orientation of the line features on the ceiling are detected in the input image, and used for guiding the direction of motion of a robot. In order to detect line information robustly, preprocessing steps such as lens calibration, noise cancelling, feature enhancement are employed. An also, to enhance the accuracy and the speed, we employed Intel IPL(Image Processing Library) for the implementation. The developed vision-based navigation system is quite reliable so that it can be used in a variety of natural circumstances, for example, home, office, factory, and so on. The performance of the developed system has been tested in many real environments, and shows excellent results in both accuracy and speed.

CYP1A1, GSTM1, and GSTT1 polymorphisms, smoking, and lung cancer risk in a pooled analysis among Asian populations.

Lee, Kyoung-Mu,Kang, Daehee,Clapper, Margie L,Ingelman-Sundberg, Magnus,Ono-Kihara, Masko,Kiyohara, Chikako,Min, Shen,Lan, Qing,Le Marchand, Loic,Lin, Pinpin,Lung, Maria Li,Pinarbasi, Hatice,Pisani, P American Association for Cancer Research 2008 Cancer Epidemiology, Biomarkers & Prevention Vol.17 No.5

<P>To evaluate the roles of CYP1A1 polymorphisms [Ile 462Val and T 6235C (MspI)] and deletion of GSTM1 and GSTT1 in lung cancer development in Asian populations, a pooled analysis was conducted on 13 existing studies included in Genetic Susceptibility to Environmental Carcinogenesis database. This pooled analysis included 1,971 cases and 2,130 controls. Lung cancer risk was estimated as odds ratios (OR) and 95% confidence intervals (95% CI) using unconditional logistic regression model adjusting for age, sex, and pack-year. The CYP1A1 6235C variant was associated with squamous cell lung cancer (TC versus TT: OR, 1.42; 95% CI, 0.96-2.09; CC versus TT: OR, 1.97; 95% CI, 1.26-3.07; P trend = 0.003). In haplotype analysis, 462Val-6235T and Ile-C haplotypes were associated with lung cancer risk with reference to the Ile-T haplotype (OR, 3.41; 95% CI, 1.78-6.53 and OR, 1.39; 95% CI, 1.12-1.71, respectively). The GSTM1-null genotype increased squamous cell lung cancer risk (OR, 1.36; 95% CI, 1.05-1.77). When the interaction was evaluated with smoking, increasing trend of lung cancer risk as pack-year increased was stronger among those with the CYP1A1 6235 TC/CC genotype compared with those with TT genotype (P interaction = 0.001) and with the GSTM1-null genotype compared with the present type (Pinteraction = 0.08, when no genotype effect with no exposure was assumed). These results suggest that genetic polymorphisms in CYP1A1 and GSTM1 are associated with lung cancer risk in Asian populations. However, further investigation is warranted considering the relatively small sample size when subgroup analyses were done and the lack of environmental exposure data other than smoking.</P>

Identification and Application of Biomarkers in Molecular and Genomic Epidemiologic Research

Lee, Kyoung-Mu,Han, So-Hee,Park, Woong-Yang,Kang, Dae-Hee The Korean Society for Preventive Medicine 2009 예방의학회지 Vol.42 No.6

Biomarkers are characteristic biological properties that can be detected and measured in a variety of biological matrices in the human body, including the blood and tissue, to give an indication of whether there is a threat of disease, if a disease already exists, or how such a disease may develop in an individual case. Along the continuum from exposure to clinical disease and progression, exposure, internal dose, biologically effective dose, early biological effect, altered structure and/or function, clinical disease, and disease progression can potentially be observed and quantified using biomarkers. While the traditional discovery of biomarkers has been a slow process, the advent of molecular and genomic medicine has resulted in explosive growth in the discovery of new biomarkers. In this review, issues in evaluating biomarkers will be discussed and the biomarkers of environmental exposure, early biologic effect, and susceptibility identified and validated in epidemiological studies will be summarized. The spectrum of genomic approaches currently used to identify and apply biomarkers and strategies to validate genomic biomarkers will also be discussed.

Molecular Epidemiological Study on Environmental and Genetic Risk Factors of Pediatric Cancer in Korea

Kyoung-Mu Lee,Yoon-Ok Ahn,Daehee Kang,Moon-Ho Chung 한국환경보건학회 2005 한국환경보건학회 학술대회 자료집 Vol.2005 No.-

Urinary Levels of phthalate metabolites in Korean population: KorSEP data, 2009

( Kyoung Mu Lee ),( Young Lim Kho ),( Jae Buhm Chun ),( Pan Gyi Kim ),( Suk Hwan Park ),( Jin Heon Lee ) 대한보건협회 2011 대한보건협회 보건종합학술대회 Vol.2011 No.-

[Background] Phthalates are ubiquitous industrial chemicals used as plasticizers, solvents, lubricants, and stabilizers in the manufacture of consumer products such as children`s toys, medical equipment and medications, cosmetics, and food packaging. Assessing human exposure to phthalates is of interest because of their potential adverse health effects, particularly among the young. [Objective] The national survey for environmental exposure monitoring in 2009 were funded by Korea Food of Drug Administration (KFDA) with a view to assessing human exposure to selected chemicals including phthalates and identifying major sources of them. [Methods] The subjects of our study aged between 18 and 70 were selected through stratified sampling nationwide and interviewed by trained interviewers using structured questionnaire to collect information on general characteristics, use of plastics, dietary habits related with potential exposure to phthalates. Total 1,874 urine samples were collected and stored at -20℃ until measurement for 10 selected metabolites of phthalates using HPLC (high performance liquid chromatography). Out of 10 metabolites, six ones were selected for further statistical analyses based on proportion of samples over LOQ (limit of quantification), i.e, MnBP, MiBP, MbZP, MeHP, MeOHP, and MeHHP. For each urinary levels (ug per gram creatinine), geometric mean and 50th, 75th, 90th, 95th were represented. Given the distribution of response variable deviates from normal distribution, log transformation was performed, and then tested for its statistical significance. Differences by selected variables were analyzed for statistical significance by ANCOVA (analysis of covariance) adjusted for age, sex, income, and body mass index. [Results] Common phthalate metabolites included MnBP (GM=41.7, GSE=1.9), MeHHP (38.1, 1.9), MeOHP (17.5, 1.9), MiBP (17.0, 2.2), and MBzP (15.8, 2.8), whereas the proportion of data above LOQ was less than 20 for MCHP, MnOP, MiNP, and MiDP. The levels for the six metabolites tended to be higher compared to those from the national survey in US (NHANES), and lower compared to those from the national survey in Germany (GerES4). Significant correlations between the six urinary metabolites were observed. Urinary level of phthalates were observed to be higher among subjects with older age, females, subjects with higher body mass index (BMI), and lower income.

Meta-analysis of the association between exposure biomarker levels of lead and autism spectrum disorder among children

Kyoung-Mu Lee(이경무),Se-Eun Oh(오세은),Mina Ha(하미나) 환경독성보건학회 2015 한국독성학회 심포지움 및 학술발표회 Vol.2015 No.10

Shape from texture using parametric surface model under orthographic projection

Lee, Kyoung-Mu Research Institute for Science & Technology HONG-I 1997 Hongik Journal of Science and Technology Vol.1 No.-

In this research, we propose a new shape from texture (SFT) algorithm which recovers the surface heights of curved objects covered with fairly homogeneous texture directly. By examining the orthographic transformation of a local planar surface patch onto the image plane,we establish a nonlinear relationship between the measured local density of texture primitives on the image plane and the orientation and position of the surface patch in the world space. By approximating a surface with a parametric surface model, we can relate the densities of textural primitives in triangular domains to nodal height variables of the curved surface. This procedure leads to a nonlinear system of equation which are then solved via a successive linearizatin. Experimental results are given to illustrate the performance of the new algorithm.

Table extraction and analysis algorithm from document images

Lee,Kyoung Mu,Lee,Sang Hyeop Research Institute for Science & Technology HONG-I 1998 Hongik Journal of Science and Technology Vol.2 No.-

A new algorithm to detect a table and analyze its layout structure in a document image is presented in this paper. This technique enables intelligent and robust processing of table images, and hence greatly enhance the performance of the existing OCR system so that it can be applied efficiently to a lot of real applications. Moreover, since the proposed preprocessing techniques including noise cancelling, line extraction, and corner feature detection shows excellent performance, it can be applied efficiently to similar problems in document and form processing tasks. The experimental results with real images of tables show that the performance of the proposed algorithm is quite reliable and accurate.