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        치성낭종으로부터 유래된 편평상피세포암종 : Report of a Case & Review of Literatures

        권혁진,현재훈,박형국,김용각 大韓顎顔面成形再建外科學會 1997 Maxillofacial Plastic Reconstructive Surgery Vol.19 No.2

        Odontogenic cysts are relatively common pathologic lesions found in the oral and perioral structures, but the case of squamous cell carcinoma arising from those cysts are very uncommon. After first reported of that case in 1889 by Herman, Schwimmer collected 56 cases of previously reported squamous cell carcinoma arising in residual odontogenic cyst during about past one century. More than 60% of cases of carcinoma developing in odontogenic cysts arising in inflammatory periapical or residual cyst, and these tumors are usually well-differentiated with relatively good prognosis, and often are diagnosed as benign lesion in radiographic or clinical examination, therefore definitive diagnosis must be made by histologic examintation. We report a case and review the literatures, in our case, 78-year old woman were clinically and radiographically diagnosed as residual odontogenic cyst. But in histologic examination after enucleation of lesion, mass of squamous cell carinoma were observed, but in other area, typical cyst wall and lining epithelium were observed. And in some area, carcinoma in situ and invading squamous cell carcinoma into the lining epithlium were also observed.

      • Paste법에 의한 0.1V강의 침붕처리에 관한 연구

        권동일,김강형,김진관,이성훈,윤재홍 國立 昌原大學校 産業技術硏究所 1994 産技硏論文集 Vol.8 No.-

        0.1V강의 표면경도를 향상시키기 위해서 Boronizing처리를 실시하여 Hv=1500∼2000의 높은 경도값을 나타내는 붕화물층을 얻었다. 붕화물층의 두께와 처리시간과의 사이에는 방물선관계를 나타내었으며 붕화물층 생성 겉보기 활성화에너지는 94kJ/mol이다. 또한 900˚C, 3시간 침붕처리했을 때가 가장 높은 경도분포값을 나타내었으며 그 이상 장시간 처리하면 오히려 경도가 감소하는 경향을 나타낸다. 그리고 침붕층은 20% HCl, 20% H₂SO₄용액에서는 뛰어난 내식성을 가지나, 20% HNO₃용액에 대해서는 상대적으로 내식성이 떨어졌다. 그리고 내고온산화성은 대기중 800˚C까지는 침붕처리한 시편이 우수했으나 900˚C부터는 오히려 감소했다. To improve the surface hardness of the 0.1V steel, by Boronizing Treatment, We got boride layer showing high hardness, Hv=1500∼2000. A parabola relationship was appeared between boride layer thickness and treatment time, and apparent activation energy to form the boride layer 94kJ/mol. Moreover, We obtained the most high hardness distribution value when had the boronizing treatment for 3 hours at 900˚C. On the contrary, If we did boronizing treatment above 3 hours, the hardness appeared decreasing tendency. The boride layer had a good corrosion resistance at a solution of 20% HCl and 20% H₂SO₄, but correlatively the corrosion resistance of the boride layer was declined at a solution of 20% HNO₃. And the boronized specimen had a good high temperature oxidation resistance until 800˚C in the atmosphere but the high temperature oxidation resistance go down above 900˚C.

      • 유아의 기관절개술에서 발관방지를 위해 고안된 기관절개 튜브

        권진형,김성운,오천환 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

        Tracheostomy in infants and children is associated with a high rate of accidental decannulation in the early postoperative period. The most common complication in infants and children, which most often results in death, is accidental decannulation. Other authors advocate suturing tracheostomy tubes in place in infants and children under general anesthesia in operating room for avoiding decannulation. The authors designed tracheostomy tube for the prevention of accidental decannulation following tracheostomy in infant, so report with review of literatures.

      • 기관내 삽관 후 발생한 기관 괴사와 협착증 : 증례보고 A case report

        권진형,구자욱,유시현 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

        Tracheal necrosis and stenosis are rare complications of prolonged endotracheal intubation. A 62 years old female was performed cerebral aneurysmal neck clipping under general anesthesia via endotracheal intubation and transferred to the 12th intensive care unit. The patient was mechanically ventilated and tracheostomy was done on the postoperative day. Necrotic tissue, pus and stenosis were found around the ballooning site of the trachea. T-tube insertion was done on the both postoperative day and the patient was discharged on the 80th postoperative day.

      • 신호의 충실성을 위한 고속 통신 시스템의 신호 선로 설계 방법론

        이진형,장종권 울산대학교 1998 공학연구논문집 Vol.29 No.2

        최근의 반도체 및 시스템 기술의 급격한 발달로 인하여 고속 통신 시스템(High-speed Communication system)의 동작 주파수(Operating Frequency)가 매우 빨라지게 되었다. 이러한 고속 통신 시스템의 Backplane상에는 신호의 충실성(Signal Integrity)을 저해하는 많은 요소들이 존재한다. 본 논문에서는 고속 통신 시스템의 내부 잡음들이 신호에 미치는 영향을 모형화하고 잡음의 영향을 최소화할 수 있는 새로운 Backplane 설계 방법론을 제안한다. 설계 방법론을 제시하기 위해 신호 경로의 특성값을 구하고, 최적의 시뮬레이션(Simulation) 모형을 구하는 과정에 대해 언급한다. 이 과정들을 통해 얻어진 결과를 기존 시스템의 시뮬레이션 결과와 비교하여 고속 통신 시스템의 성능을 향상시킬 수 있음을 증명한다. The operating frequency of High-speed Communication System becomes very fast with the advance -d technology of VLSI chips and system implementation. There may exist various types of noise sources degrading the signal integrity in this system. In this paper, we model the effects of the internal noises in the High-speed Communication System to the signal line and propose a new design method to minimize these effects. For the design methodology, we derive the charact -erization value for each model and then construct the optimal simulation model. Finally, we compare the result of the new method with that of the existing method, through simulation and show that the quality of High-speed Communication System is significantly enhanced.

      • 구강 편평세포암종에서 E-cadherin 및 β-catenin 발현의 변화 : Correlation with Histologic Features and p53 Expression

        서진건,권창석,박진배,윤혜경,김우형,이희철 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.4

        Objective : Altered expression of cell adheion molecules is associated with biologic behavior of tumor. The aim of this study is to evaluate the expression pattern of E-cadherin, β-catenin and p53 protein according to histologic grade and invasion pattern of squamous cell carcinoma of the oral cavity and the relationship between E-cadherin, β-catenin and p53 protein expression. Methods and Material : The materials were fifty seven cses of squamous cell carcinoma, and clinicl parameers such as age, sex, tumor location, stage and recurrence were recorded. Histologic review was done based on histologic grade and invasion pattern(nodular vs infiltrative). Immunohistochemical stains for E-cadherin and β-ca tenin were interpreted based on staining pattern as los of membranous expression and cytoplasmic expression and p53 protein expression was defined as positive if more than 10% of nuclei were reactive. Statistical analysis between E-cadherin, β-catenin and p53 protein expressions and histologic grade and invasion pattern and the relationship between E-cdherin, β-catenin and p53 protein expressions were perfomed. Results : There wa positive correlation between higher histologic grade and infiltrative pattern. Loss of membranous expression and cytoplasmic expression of E-cadherin were noted in 33.3% and 57.9%, respectively, and loss of membranous expression of E-cadherin showed increaing tendency in poorly differentiated carcinomas, however, there was no significant difference of cytoplasmic expression rate of E-cadherin according to histoogic grade. Altered expression of E-cadherin was more frequent in poorly differentiated carcinomas. Loss of membranous expression and cytoplasmic expression of E-cadherin were more frequent in carinomas with infiltrative pattern than in carcinomas with nodular pattern, but their diferences were not significant, Loss of membranous expression and cytoplasmic expression of β-catenin were observed in 19.3% and 80.7%, respectively. Loss of membranous expression of β-catenin howed no positive correlation according to histologic grade and invasion pattern, but cytoplasmic expression rate of β-catenin was higher in poorly differentiated carcinomas and in carcinomas with infiltrative pettern. p53 protein expression rate was 45.6%, and showed invreasing tendency in poorly differentiated carcinomas, but no significant relationship with invasion pattern. There was an inverse relationship of loss of membranous expression and cytoplasmic expression of E-cadherin and β-catenin. Altered expression of E-cadherin was related to cytoplasmic expression of β-catenin, however, there were no significant relationship between altered expressions of E-cadherin and β-catenin and p53 protein expression. Conclusion : In squamous cell carcinomas of the oral cavity, altered expression of E-cadherin and β-catenin was more frequent in poorly differentiated carcinomas and in carcinomas with infiltrative pattern and there was positive correlation betwween altered expression of E-cadherin and β-catenin. These findings suggest that altered expressions of E-cadherin and β-catenin may have a role in the development of squamous cell carcinomas with aggressive biologic behavior. but altered explosions of E-cadherin and β-catenin. These findings suggest that altered expressions of E-cdherin and β-catenin my have a role in the development of squmaous cell carcinomas with aggressive biologic behavior. But altered expression of E-cadherin and β-catenin might not be related to p53 protein expression. Further study on genetic mutation related to altered expression of E-cadherin and β-catenin will be needed

      • 초임계 유체에서 용해도 파라미터에 의한 고체 용해도 예측

        洪仁權,金炯辰,林秀貞 단국대학교 1994 論文集 Vol.28 No.-

        Solubility of solids was calculated by using a Peng-Robinson EOS and Flory-Huggins theory with solubility data of solids in supercritical carbon dioxide which was studied recently. Theoretical solubility data of solids were obtained by applying Peng-Robinson EOS with k_ij data, interaction parameter which was calculated by nonlinear regression method. Experimental solubility data which were studied by many researchers were compared with solubility data which were calculated by Peng-Robinson EOS. And, it was assumed that Peng-Robinson binary interaction parameter, k_ij(k_ii = k_jj = 0, k_ij = k_ji) is independent on temperature, pressure, and component, but k_ij is dependent on temperature in high pressure nonideal fluid mixture. Interaction parameter, β_12 between solvent and solute which was calculated by using a Flory-Huggins theory is dependent on solubility parameter of solvent, δ. There's relationship that interaction parameter, β_12 and solubility parameter δ are independent on temperature. It was modeled using a Cubic Spline method.

      • 인대내 거대자궁 근종 증례

        김윤진,전명권,이응수,최형민 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.4

        Uterine myomas are the most common pelvic tumor in women. These benign tumor generally arise in the uterinie wall and intraligamentary myomas are relatively rare cases. We experienced intraligamentary huge myoma. Preoperative GnRH(Gonadotropin Releasing Hormone) agonist therapy was done but the effect was nearly absent. Hystrectomy was done without complication. We report this case with brief review of literatures.

      • 중복 자궁 경부, 맹낭성 종질중격 및 동측 신장발생부전을 가진 교통성 중복자궁 1례

        김윤진,전명권,이응수,최형민 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.4

        The class of uterine malformation known as communicating uteri is characterized by two uterocervical cavities connected by an isthmic communication. We experienced case of communicating double uterus with double cervix, blind hemivagina and ipsilateral renal agenesis. The complaint of the patient was odorous vaginal discharge with lower abdominal pain unrelated with menstrual cycle. We confirmed these Mullerian anomalies by transvaginal ultrasound. IVP(intravenous pyelography), MRI(magnetic resonance imaging), hysterosalpingography and hysteroscopy. After vaginal septoplasty, her complaint was subsided. We report this case with brief review of literatures.

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