인터넷 조사를 이용한 구성원 정보 데이터베이스 시스템 설계 및 구현

곽난희,남기성,문덕희,박희창 창원대학교 정보통신연구소 2000 精報通信論文集 Vol.4 No.-

A system that designed and implemented in this paper was composed of database system, online survey system, OLAP system, and online report system. Data of this system put in online survey system, and summated past saved database data. And OLAP system analyzed input data. Online report system prints output at real time that composed of basic information(tables and graphs etc.) for policy determine. All system operate on WWW. Also this data are using in high class statistics program.

무 추출물이 식품관련 미생물의 증식에 미치는 영향

곽희진,계수경,곽희선,이경혜 동아시아식생활학회 2000 동아시아식생활학회지 Vol.10 No.4

To understand the effect of radish on growth of food born microorganisms, mashedflesh radishes were extracted by using acetone and distilled water. Their effect was assayed by measuring the optical density of cultural broth of food born microorganisms, In the experiment, seven strains of food born bacteria and one strain of yeast were used as the test organism. Acetone extract inhibited growth of the cells of L. plantarum, L. sake and Danmuji film yeast. Growth of the film yeast was drastically inhibited in the concomitant presence of 0.03% extract, while other microbes such as L. faecalis. P. pentosaceus, B. subtilis and E. coil grew by succeeding cultivation for 4 to 8 hours after addition of the extract. Water extract, on contrast to acetone extract, at the concentrations of 0.1~1.5% stimulated the growth of lactic acid bacteria, Culture of L. faecalis and L. sake showed an optical density higher than that of control by 40~50 times. The effect was not so apparent against E. coli, S. aureus and Danmuji film yeast.

회전원통을 이용한 초고압 변압기의 유동대전에 관한 연구

곽희로,권동진,손철근 崇實大學校 生産技術硏究所 1993 論文集 Vol.23 No.-

This paper presents the measurement method using a spinning cylinder system for streaming electrification of transformer oil. The spinning cylinder system has a simple mechanical construction, and requires less oil compared to the other methods. Also, the effects of various admixtures on the static electrification properties of transformer oil can be easily investigated. Experiments showed that addition of the BTA reduced the streaming electrification and the polarity of static electrification was converted to negative at 50∼70[ppm] of BTA.

Extended-spectrum β Lactamase (ESBL) 음성과 양성인 Klebsiella pneumoniae 혈류 감염증 환자의 임상적 특성 및 예후 비교

곽희원 외 중앙대학교 의과대학 의과학연구소 2009 中央醫大誌 Vol.34 No.1/2

ESBL-producing Klebsiella pneumoniae are resistant to many antibiotics, and bloodstream infections by ESBL-producing Klebsiella pneumoniae are known to increase the treatment failure and the mortality rate, but further Korean studies are required. We conducted this study to test the hypothesis that the clinical outcomes and prognosis amomg patients with bloodstream infection by ESBL-non-producing Klebsiella pneumoniae and by ESBL-producing Klebsiella pneumoniae are different. One hundred forty two patients with a bloodstream infection by Klebsiella pneumoniae were enrolled in this study from January, 2003 to May, 2007 at Chung-Ang University Hospital. Demographic characteristics, the mortality rate, hospitalization, site of infection, underlying disease and source of infection were assessed and compared between patients with bloodstream infection by ESBL-non-producing Klebsiella pneumoniae and by ESBL-producing Klebsiella pneumoniae by a retrospective analysis. Age, sex, site of infection, underlying disease showed no significant difference between patients with bloodstream infection by ESBL-non-producing Klebsiella pneumoniae and by ESBL-producing Klebsiella pneumoniae. But the infections by ESBL-producing organism more developed among patients with longer hospitalization and longer recovery period than the infections by ESBL-non-producing organism, but the motality rate showed no significant difference. The infections by ESBL-nonroducing organism were mostly community acquired, whereas the infections by ESBL-producing organismswere mostly hospital acquired. In intensive care units, the infections by ESBL-producing organism needed significantly longer Intensive Care Unit hospitalization, but the motality rate showed no significant difference.

돈육의 위생화와 품질보존을 위한 감마선 조사

곽희진,계수경,강일준 동아시아식생활학회 1998 동아시아식생활학회지 Vol.8 No.4

이상의 결과로 돼지고기는 비교적 미생물 오염도가 낮아 1 kGy조사로 저온성 미생물을 제외한 오염미생물의 생육을 검출한계 이하로 감소시킬 수 있었으며 모든 오염미생믈의 살균을 위해서는 3kGy의 선량이 요구되었다. 감마선조사와 저장기간에 따른 일반성분 변화의 경우 수분함량에 있어서만이 저장기간에 따라 다소 감소되었으며, pH 및 산도는 감마선 조사에 의한 영향은 없었으나 저장기간이 경과함에 따라 pH는 증가하고 산도는 감소하는 경향을 보였다. 총아미노산 조상에서는 가장 많이 검출된 것이 glutamic acid였고, 감마선 조사에 의한 영향도 매우 미비하였다. 무기질 함량의 경우 주요 무기질 성분으로 potassium, phosphorus, sodium, magnesium 순이었고 감마선 조사에 의한 조성변화는 없었다. Meat is a perishable product since it offers favorable conditions for microbial contamination and multiplication. Besides, undercooked and raw meat has been linked to outbreaks of hemorrhagic diarrhea due to the presence of microbial pathogens. Therefore, this study was conducted to find out the effect of the use of gamma-irradiation in order to improve preservation and eliminate this microorganisms. The initial level of microbial contamination in pork was 1.1×10⁴ CFU/g (aerobic bacteria), 5.3×10³ CFU/g (psychrophile), 3.1×10³ CFU/g (coliforms) and 3.2×10³ CFU/g (Listeria), All kinds of contaminated microorgnisms were sterilized by gamma irradiation at 3 kGy. The proximate composition of pork was not significantly changed by irradiation dose and storage period. The pH was slightly increased during storage period and titratable acidity decreased. However, no significant changes in pH and acidity were observed by gamma irradiation. There was no difference in total amino acid content regardless of irradiation dose and storage period. Glutamic acid was detected at high levels throughout the storage period. The major mineral compositions of pork were potassium, phosphorus, sodium, magnesium. No significant difference in the components of minerals were observed by gamma irradiation.

시상부위에 발생한 단일성 뇌농양 : 증례 보고 및 문헌고찰 Report of Two Cases and Review of the Literature

곽호신,김동규,이상형,정희원,이현구,김현집,한대희 대한신경외과학회 1992 Journal of Korean neurosurgical society Vol.21 No.12

The authors present two cases of solitary thalamic abscess which were intially diagnosed as malignant thalamic glioma. After treatment with steroids and osmotic agents, the patients' clinical conditions improved after two to three days. However, sudden deterioration of consciousness level developed and the CT scan showed acute hydrocephalus with increment of thalamic low-density lesions. We performed extraventricular drainage and obtained CSF containing numerous inflammatory cells. This suggested the possibility that the lesion was a pyogenic abscess. which progressed to ventriculitis, rather than a malignant glioma. Stereotactic aspiration of the lesion confirmed thalamic abscess. These findings and review of previous reports of thalamic abscess suggested that early diagnosis and stereotactic drainage of the thalamic abscess is of primary importance.

비동기 카오스 비밀통신의 변복조 기술평가

곽부동,김성곤,최희주,변건식 동아대학교 정보기술연구소 2000 情報通信硏究所論文誌 Vol.8 No.1

During the past five years, there has been tremendous interest worldwide in the possibility of exploiting chaos in wideband communication systems. Many different demodulation techniques have been proposed up to date. They can be divided into two basic categories. In the first approach, like the conventional coherent demodulation techniques, the chaotic signal has to be recovered from the received noisy signal by synchronization. However, the chaotic synchronization techniques published to data are so sensitive to the channel noise and distortion that these techniques can not be used in radio communications. In the second approach, the demodulation is carried out nonsynchronization. This paper surveys the different chaotic communication techniques that can be implemented nonsynchronization and compares the threshold and BER of the different methods. Finally, FM-DCSK is introduced the first step for apply to wideband chaos digital CDMA, where the data is not limited by the inherent nonperiodic property of the chaotic signal.

고전압 급준펄스의 오버슈트 개선에 관한 연구

곽희로,권동진,김영찬 崇實大學校 生産技術硏究所 1994 論文集 Vol.24 No.-

This paper describes very fast rising high voltage pules generation using the traveling wave theory of the transmission line. This very fast rising high voltage pulse generator consists of a charging coaxial cable, a discharging switch, and a terminating resistance. The results of the study show that the rising time of pulses is very fast about 30 [nsec]. The length of the coaxial cable and the charging voltage can regulate the duration and the amplitude or the polarity of the pulse. In addition, rod to plane electrodes are suitable as a short switch and the overshoot of pulse was improved with the larger radius of the rod electrode.

Satellite-Pulse Technique(SPT)를 이용한 결함의 크기측정

곽경진,안희성,정용무,이영필 韓國非破壞檢査學會 1981 한국비파괴검사학회지 Vol.1 No.1

소위Satellite-Pulse Technique(SPT)을 이용하여 인공결함의 크기를 측정하였다. 측정치와 실제치를 비교하였는바 오차는 무시할 정도이었다. Sizing of artificial flaws is accomplished by ultrasonic Satellite-Pulse Technique(SPT). Negligible error is found.

자폐장애 환자에서 FMR-1 유전 삼염기 반복의 분자생물학적 분석

곽호순,정철호,전효진,장은진,김희철,김정범,박영남 대한소아청소년정신의학회 2000 소아청소년정신의학 Vol.11 No.1

연구목적 : 자폐장애의 원인을 유전학적으로 규명하려는 연구가 시도되고 있으며, 그 중 fragile-X 증후군과의 연관성에 대한 연구가 활발히 진행되고 있다. fragile-X 염색체(Xq27.3)는 세포유전학적 방법으로 증명할 수 있으나 검사에 많은 제약과 단점이 있으므로, 본 연구에서는 보다 신뢰성이 높은 분자 생물학적 방법으로 FMR-1 유전자내 CGG 삼염기 반복부위를 분석하여 자폐장애와 fragile-X 증후군의 연관성을 규명하고자 하였다. 방법 : 자폐장애 환아(99명)와 정상대조군(8명)을 대상으로 FMR-1 유전자의 CGG 반복배열 부위를 sense와 antisense primer를 이용하여 PCR법으로 분석하엿으며, 동시에 세포유전학적 검사도 시행하였다. PCR 분석에서 CGG 반복수가 50 이상인 경우에 대해서는 StB12.3 혹은 Pfxa3 probe를 이용한 Sourthern blot hybridization으로 확인하였다. 결과 : FMR-1 유전자의 CGG 반복배열에 대한 PCR 분석 결과 CGG 삼염기의 반복배열의 수는 자폐장애 환자군과 정상대조군 사이에 통계적으로 유의한 차이가 없었다(p=0.207). 자폐장애 환자에서 CGG 반복수가 50회 이상인 조기변이(premutation) 환자가 2명 있었으나 Sourthern blot hybridization 결과 완전변이(full mutation)로 판정할 수 있는 경우는 없었다. 세포유전학적 검사에서 환자군 모두에서 정상 핵형을 나타내었으며 fragile-X 염색체는 확인되지 않았다. 결론 : 이상의 결과에서 자페장애 환자가 FMR-1 유전자의 CGG 삼염기 반복부위 이상, 즉 fragile-X 염색체 이상을 동반하지 않았음을 증명할 수 있었다. 이는 fragile-X 증후군을 자�장애의 직접적인 원인이라고 보기에는 어려움이 있음을 시사한다. Objectives : There has been a rapid expansion of studies aimed at elucidating the genetic basis of autistic disorder, especially it's relationship to fragile-X syndrome. The detection of fragile X chromosome(Xq27.3) by cytogenetic analysis has revealed many difficulties in testing. Therefore, to explore the relationship between autistic disorder and fragile X syndrome, this study administered molecular biologic methods which examined an unstable CGG repeat within the fragile X mental retardation-1(FMR-1) gene. Methods : Ninety nine autistic children and eight normal control children were tested. The number of CGG repeats within FMR-1 gene was measured after amplification by PCR, and cytogenetic analysis was also carried out to detect fragile site Xq27.3. Sourthern blot hybridization, using StB12.3 and/or Pfxa3 probe, was done for the patients showing expansion of more than 50 CGG repeats(premutation). Results : All but two autistic patients had no expansion in CGG repeats by PCR and there was no significant statistical difference in number of CGG repeat in comparison with normal control. Two autistic patients, considered as premutation by PCR analysis, had no full mutation or premutation by Southern blot hybridization. All autistic children tested did not have any abnormal karyotype or fragile site Xq27.3. Conclusions : These results suggest that autistic patients may not have abnormality in FMR-1 gene or abnormal expansion in CGG repeat. In conclusion, fragile X syndrome may not be antecedent of autistic disorder. KEY WORDS : Autistic disorder·FMR-1 gene trinucleotide repeats·Molecular biologic analysis.