Development of Evaluation Norm for Physical Fitness On Sasang Constitutions in Female College Students

( Sang-hyun Kim ),( Sung-eun You ),( Tae-yeong Kim ),( You-sun Ko ) 한국체육학회 2016 국제스포츠과학 학술대회 Vol.2016 No.1

Purpose: This research aims to develop the evaluation norm of physical fitness of women college students based on Sasang constitutional types and with these, to provide materials necessary to tailored exercise programs by individual differences and develop physical education programs for improving physical competence. Method: From 2008 to 2015, targeted students of S Women’s university located in Seoul Korea, total 1,263 answered questionnaires and were measured their strength. The data were classified by the Sasang constitution analysis program (QSCCⅡ): So-Yang type n=449, So-Eum type n=542, Tae-Eum type n=272. Measurement variables of Physical fitness are Muscular strength(grip strength, back strength), Muscular endurance(sit-up), Power(standing long jump), Agility(tapping), Flexibility(trunk flexion). For data analysis, with SPSS 18.0 technological statistics and One-way ANOVA were carried out, adapting 5-level by Cajori. Result: 1. The physical fitness has significant differences among Sasang constitutional types: Tae-Eum type has best muscular strength and So-Yang type had the highest Power. 2. By comparing evaluation norm of physical fitness of total women students with those of physical fitness on Sasang constitutional types showed different figures< Table. 1 > Conclusion: This research implicates that the evaluation norm of physical fitness on Sasang constitutional types may provide more detailed and accurate one. Furthermore, by presenting reliable workout programs, more healthy and satisfactory results-improvement of exercise competence-can be acquired. Future researches will contribute to develop customized workout programs on Sasang constitutional types for not only women students but people of all ages.

Chaetoglobosin A, an Inhibitor of Bleb Formation on K562 Cells Induced by Phorbol 12,13-Dibutyrate

KO, HACK-RYONG,KIM, BO YEON,AHN, SOON-CHEOL,OH, WON KEUN,KIM, JIN-HEE,LEE, HYUN SUN,KIM, HWAN-MOOK,HAN, SANG-BAE,MHEEN, TAE0ICK,AHN, JONG-SEOG 한국미생물 · 생명공학회 1998 Journal of microbiology and biotechnology Vol.8 No.6

Association between Sasang constitutional types with obesity factors and sleep quality

Tae Yeong Kim,Sung Eun You,You-Sun Ko 한국한의학연구원 2018 Integrative Medicine Research Vol.7 No.4

Background: The purpose of this study was to investigate differences in obesity factors according to Sasang constitutional types and quality of sleep among Korean female college students. Methods: Surveys using Sasang-types questionnaires(QSCCⅡ) and quality of sleep questionnaires(PSQI; Pittsburgh Sleep Quality Index) were conducted with 339 Korean female college students. Additionally, obesity factors, including weight, fat mass, fat percent, abdominal fat percent, body mass index (BMI) and obesity rates were measured. All data analyses were performed using one-way ANOVA and two-way ANOVA. Results: The interaction between Sasang types and quality of sleep was presented in the quality of sleep status, subjective quality of sleep (domain 1), sleep duration (domain 3) and sleep disturbance (domain 5). Variables with interaction effects had significant differences in terms of obesity factors between groups with different quality of sleep according to the Sasang types. Moreover, significant differences in obesity factors between different Sasang types according to the quality of sleep were also observed. Conclusion: This study characterized the reduction effect of improvement in quality of sleep on the fat mass of So-Yang type individuals and obesity factors in Tae-Eum type individuals. The results of this study will be used in improving sleep quality according to the Sasang types.

맨드라미(Celosia cristata L.) 꽃 메탄올 추출물로부터 용매분획된 분획물의 항산화활성

김현영(Hyun Young Kim),고지연(Jee Yeon Ko),송석보(Seuk Bo Song),김정인(Jung In Kim),서혜인(Hye In Seo),이재생(Jae Saeng Lee),곽도연(Do Yeon Kwak),정태욱(Tae Wook Jung),김기영(Ki Young Kim),오인석(In Seok Oh),정헌상(Heon Sang Jeong),우 한국식품영양과학회 2012 한국식품영양과학회지 Vol.41 No.11

맨드라미꽃의 식품학적 이용가능성을 확인해 보고자 항산화성분 및 항산화활성에 대해 검토하였다. 맨드라미꽃의 항산화성분과 활성은 메탄올 추출물과 순차적 용매분획물에 대해 측정하였으며, 메탄올 추출물과 hexane, chloroform, ethyl acetate, butanol 및 물 분획물의 추출수율은 각각 23.33, 10.27, 20.00, 13.63, 17.55 및 38.54%였다. 맨드라미 꽃 메탄올 추출물의 총 polyphenol, flavonoid 및 tannin 함량은 각각 6.80 ㎎ GAE/g ME, 2.34 ㎎ CE/g ME 및 6.23 ㎎ TAE/g ME였다. 순차적 용매분획물 중 butanol 분획에서 각각 14.92 ㎎ GAE/g SF, 5.44 ㎎ CE/g SF 및 13.38 ㎎ TAE/g SF로 함량이 높았다. 총 proanthocyanidin 함량은 44.72 ㎍ CE/g ME였고 순차적 용매분획물은 각각 42.47, 44.43, 50.03, 49.12 및 41.80 ㎍ CE/g ER로 용매간 유의적인 차이를 보이지 않았다. 맨드라미꽃의 메탄올 추출물의 DPPH 및 ABTS radical 소거활성은 각각 5.24 및 10.70 ㎎ TE/g ME였고 butanol 분획에서 각각 12.53 및 21.09 ㎎ TE/g SF로 활성이 높았다. 메탄올 추출물의 SOD 유사활성은 7.96 unit/mL로 나타났고 hexane, chloroform, ethyl acetate, butanol 및 물 분획물은 각각 4.56, 6.15, 8.07, 12.36 및 5.21 unit/mL로 butanol 분획의 활성이 높았다. 맨드라미꽃 추출물의 항산화성분과 항산화활성 간에 높은 정의 상관관계를 보였고 맨드라미꽃 추출물이 체내 및 식품에서 유익한 도움을 줄 수 있을 것으로 생각된다. The purpose of this study was to evaluate the antioxidant contents and activities of solvent fractions from methanolic extracts of cockscome flowers. The yield of methanolic extracts from cockscome flowers was 23.33%, whereas those of its solvent fractions (hexane, chloroform, ethyl acetate, butanol, and water) were 10.27, 20.00, 13.63, 17.55, and 38.54%, respectively. Total polyphenolic, flavonoid, tannin, and proanthocyanidin contents of methanolic extracts (ME) were 6.80 ㎎ gallic acid equivalent (GAE)/g ME, 2.34 ㎎ catechin equivalent (CE)/g ME, 6.23 ㎎ tannic acid equivalent (TAE)/g ME, and 44.72 ㎍ CE/g ME, respectively. The highest total polyphenolic, flavonoid, and tannin contents of solvent fractions were 14.92 ㎎ GAE/g solvent fraction (SF), 5.44 ㎎ CE/g SF, and 13.38 ㎎ TAE/g SF in the butanol fraction, respectively. The total proanthocyanidin contents were 42.47, 44.43, 50.03, 49.12, and 41.80 ㎍ CE/g SF, respectively. The DPPH and ABTS radical scavenging activities from cockscome flowers were 5.24 and 10.70 ㎎ Trolox equivalent (TE)/g ME, respectively. The highest DPPH and ABTS radical scavenging activities of the solvent fractions were 12.53 and 21.09 ㎎ TE/g SF in the butanol fraction, respectively. SOD-like activities of methanolic extracts from cockscome flowers were 7.96 units/mL, whereas those of its solvent fractions were 4.56, 6.15, 8.07, 12.36, and 5.21 units/mL, respectively. The results of this study show that notable antioxidant activities in cockscome flowers have significant health benefits.

비수리(Lespedeza cuneata G. Don) 메탄올 추출물로부터 분획된 용매분획물의 항산화활성과 α-Glucosidase 저해활성

김현영(Hyun Young Kim),고지연(Jee Yeon Ko),송석보(Seuk Bo Song),김정인(Jung In Kim),서혜인(Hye In Seo),이재생(Jae Saeng Lee),곽도연(Do Yeon Kwak),정태욱(Tae Wook Jung),김기영(Ki Young Kim),오인석(In Seok Oh),정헌상(Heon Sang Jeong),우 한국식품영양과학회 2012 한국식품영양과학회지 Vol.41 No.11

비수리의 식품학적 이용가능성을 확인해 보고자 항산화성분 및 항산화활성, superoxide dismutase 유사활성, α-glucosidase 저해활성 등에 대해 검토하였다. 비수리 메탄올 추출물과 hexane, chloroform, ethyl acetate, butanol 및 물 분획 등 순차적 용매분획물의 총 폴리페놀 함량은 각각 12.44, 3.61, 6.39, 27.11, 20.00 및 9.32 ㎎ GAE/g extract residue(ER)로 나타났으며, 총 플라보노이드 함량은 각각 2.94, 9.92, 7.77, 9.27, 5.11 및 2.66 ㎎ CE/g ER, 총 탄닌 함량은 각각 8.75, 10.04, 7.42, 17.32, 11.65 및 7.61 ㎎ TAE/g ER, 총 프로안토시아니딘의 함량은 346.09, 63.50, 103.76, 288.62, 231.99 및 358.48 ㎍ CE/g ER로 나타났다. 비수리 메탄올 추출물과 hexane, chloroform, ethyl acetate, butanol 및 물 분획물의 DPPH radical 소거활성은 각각 20.62, 5.16, 9.29, 20.80, 20.00 및 20.79 ㎎ TE/g ER, ABTS radical 소거활성은 각각 33.86, 9.24, 17.36, 33.76, 33.49 및 33.86 ㎎ TE/g ER로 나타났다. SOD 유사활성은 각각 4.12, 0.61, 2.01, 9.89, 13.47 및 11.82 unit/mL의 활성을 보여 butanol 분획과 물 분획에서 유의적으로 높은 활성을 나타내었고 α-glucosidase 저해활성은 물 분획 50 및 25 ㎍/mL에서 각각 93.85 및 61.64%로 높은 저해활성을 보이는 것으로 나타났다. 이상의 결과에서 비수리 추출물은 항산화성분 및 항산화활성, SOD 유사활성, α-glucosidase 저해활성을 가지는 물질을 함유한 것으로 보이며, 체내 및 식품에서 활성산소 종 제거에 도움을 줄 수 있을 것으로 보인다. The purpose of this study was to evaluate the antioxidant contents and antioxidant activities of solvent fractions from methanolic extract of sericea lespedeza. To determine the antioxidant compounds in solvent fractions from methanolic extract, total polyphenolic, flavonoid, tannin, and proanthocyanidin contents were measured by spectrophotometric methods. Solvent fractions were evaluated for antioxidative capacity according to DPPH and ABTS radical scavenging activities. Total polyphenolic contents were 12.44, 3.61, 6.39, 27.11, 20.00, and 9.32 ㎎ gallic acid equivalent (GAE)/g extract residue (ER), respectively. Total flavonoid contents were 2.94, 9.92, 7.77, 9.27, 5.11, and 2.66 ㎎ catechin equivalent (CE)/g ER, respectively. Total tannin contents were 8.75, 10.04, 7.42, 17.32, 11.65, and 7.61 ㎎ tannic acid equivalent (TAE)/g ER, respectively. Total proanthocyanidin contents were 346.09, 63.50, 103.76, 288.62, 231.99, and 358.48 ㎍ CE/g ER, respectively. DPPH radical scavenging activities of solvent fractions from methanolic extract of sericea lespedeza were 20.62, 5.16, 9.29, 20.80, 20.00 and 20.79 ㎎ Trolox equivalent (TE)/g ER, and ABTS radical scavenging activities were 33.86, 9.24, 17.36, 33.76, 33.49, and 33.86 ㎎ TE/g ER, respectively. SOD-like activities were 4.12, 0.61, 2.01, 9.89, 13.47, and 11.82 units/mL, and α-glucosidase inhibition activities were 93.85 and 61.64% at concentrations of 50 and 25 ㎍/mL in the water fraction, respectively. The results of this study show that notable antioxidant activities in sericea lespedeza have significant health benefits.

THE ALMOST SURE CONVERGENCE OF AANA SEQUENCES IN DOUBLE ARRAYS

Ko Mi-Hwa,Ryu Dae-Hee,Kim Tae-Sung Korean Mathematical Society 2006 대한수학회보 Vol.43 No.1

For double arrays of constants ${a_{ni},\;1{\leq}i{\leq}k_n,\;n{\geq}1}$ and sequences ${X_n,\;n{\geq}1}$ of asymptotically almost negatively associated (AANA) random variables the almost sure convergence of $\sum\limits{_{i=1}}{^{k_n}}\;a_{ni}X_i$ is derived.

Testosterone Stimulates Duox1 Activity through GPRC6A in Skin Keratinocytes

Ko, Eunbi,Choi, Hyun,Kim, Borim,Kim, Minsun,Park, Kkot-Nara,Bae, Il-Hong,Sung, Young Kwan,Lee, Tae Ryong,Shin, Dong Wook,Bae, Yun Soo American Society for Biochemistry and Molecular Bi 2014 The Journal of biological chemistry Vol.289 No.42

<P>Testosterone is an endocrine hormone with functions in reproductive organs, anabolic events, and skin homeostasis. We report here that GPRC6A serves as a sensor and mediator of the rapid action of testosterone in epidermal keratinocytes. The silencing of GPRC6A inhibited testosterone-induced intracellular calcium ([Ca<SUP>2+</SUP>]<I><SUB>i</SUB></I>) mobilization and H<SUB>2</SUB>O<SUB>2</SUB> generation. These results indicated that a testosterone-GPRC6A complex is required for activation of G<SUB>q</SUB> protein, IP<SUB>3</SUB> generation, and [Ca<SUP>2+</SUP>]<I><SUB>i</SUB></I> mobilization, leading to Duox1 activation. H<SUB>2</SUB>O<SUB>2</SUB> generation by testosterone stimulated the apoptosis of keratinocytes through the activation of caspase-3. The application of testosterone into three-dimensional skin equivalents increased the apoptosis of keratinocytes between the granular and stratified corneum layers. These results support an understanding of the molecular mechanism of testosterone-dependent apoptosis in which testosterone stimulates H<SUB>2</SUB>O<SUB>2</SUB> generation through the activation of Duox1.</P>

Binding mode analysis of novel HIV-1 NNRTI scaffold

KO Yoonae,CHOI Inhee,LEE Doohyun,KWON Jeongjin,KONG Sunju,JO Suyeon,KIM Youngmi,CHOI Jihyun,PARK Youngsam,KIM Junghwan,HAN Sung-Jun,KIM Tae-Hee,CECHETTO Jonathan,NAM Jiyoun,SOMMER Peter,KIM Junwon,LIU 大韓藥學會 2012 大韓藥學會 總會 및 學術大會 Vol.2012 No.1

Surface Order of Hexagonal Columnar Mesophases Induced by Molecular Assembly

Sang Ouk Kim,Young Koan Ko,Dong Ki Yoon,Sang Yoon Kang,Hee-Tae Jung 대한전기학회 2001 KIEE International Transactions on Electrophysics Vol.11C No.2

Development of Vitamin D Determination in Infant Formula by Column-Switching HPLC with UV Detector

Ko, Jin-Hyouk,Kwak, Byung-Man,Ahn, Jang-Hyuk,Shim, Sung-Lye,Kim, Kyong-Su,Yoon, Tae-Hyung,Leem, Dong-Gil,Jeong, Ja-Young Korean Society for Food Science of Animal Resource 2012 한국축산식품학회지 Vol.32 No.5

This study was carried out to develop an analytical method for the determination of vitamin D in infant formula. Vitamin D was determined by column-switching high-performance liquid chromatography (HPLC) equipped with a reversed phase column and UV detector after saponification and extraction of the formula with an organic solvent. A preseparation column ($C_8$), focusing column ($C_{18}$), analytical column ($C_{18}$) and UV-Vis detector (254 nm) were used. The limits of detection (LOD) and the limits of quantification (LOQ) for vitamin D were estimated to be $1.51{\mu}g/kg$ and $4.95{\mu}g/kg$, respectively. The linearity, recovery, precision and accuracy of the analytical method for vitamin D were evaluated through the application of a SRM (Standard Reference Material) 1846 (National Institute of Standard & Technology, USA). The linearity of this method was calculated with a value of the coefficient of determination ($r^2$) ${\geq}0.9999$. The recovery of vitamin D was $85.20{\pm}3.00%$. The intra-assay precision for vitamin D was between $1.68{\pm}0.03%$ and $5.75{\pm}0.33%$, and the inter-assay precision for vitamin D ranged from $1.73{\pm}0.03%$ to $2.96{\pm}0.09%$. The intra-assay accuracy for vitamin D was between $100.03{\pm}2.77%$ and $102.01{\pm}0.59%$, and the inter-assay accuracy for vitamin D ranged from $99.00{\pm}1.53%$ to $102.01{\pm}3.04%$. The proposed method is optimal for the separation and quantification of vitamin D from infant formula.