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( Jae Ho Lee ),( Da Eun Lee ),( Hye Min Choi ),( Ha Hyung Kim3 ),( Ho Kim ),( Jae Sam Hwang ),( Dong Gun Lee ),( Jae Il Kim ) 생화학분자생물학회(구 한국생화학분자생물학회) 2014 BMB Reports Vol.47 No.11
Defensins, which are small cationic molecules produced by organisms as part of their innate immune response, share a common structural scaffold that is stabilized by three disulfide bridges. Coprisin is a 43-amino acid defensin-like peptide from Copris tripartitus. Here, we report the intramolecular disulfide connectivity of cysteine-rich coprisin, and show that it is the same as in other insect defensins. The disulfide bond pairings of coprisin were determined by combining the enzymatic cleavage and mass analysis. We found that the loss of any single disulfide bond in coprisin eliminated all antibacterial, but not antifungal, activity. Circular dichroism (CD) analysis showed that two disulfide bonds, Cys20-Cys39 and Cys24- Cys41, stabilize coprisin’s α-helical region. Moreover, a BLAST search against UniProtKB database revealed that coprisin’s α-helical region is highly homologous to those of other insect defensins. [BMB Reports 2014; 47(11): 625-630]
김영삼,권재술 한국교원대학교 과학교육연구소 1993 청람과학교육연구논총 Vol.3 No.1
도플러 공식을 유도하는데 있어 대부분의 교과서는 파동의 진행 과정을 직접 나타내지 못함으로써 고도의 상상력을 요구하고 있다. 그러한 과정 자체가 보여주는 이해의 난점 때문에 고등학교에서는 이에 대한 교육에 어려움을 느끼고 있다. 이러한 교육적 문제점들을 줄여 보기 위한 시도로 학생들이 이해하기 쉬운 위치-시간 그래프를 이용하였고, 기초적인 삼각법을 적용하여 도플러 공식을 좀 더 쉽고 간편하게 유도할 수 있는 방법을 알아 보았다. 이 방법은 운동을 그래프로 표현하는 능력만 있으면 이해가 가능하기 때문에 보다 더 구체적인 상황과 객관적인 과정을 통하여 도플러 공식을 유도할 수 있는 장점이 있다고 사료된다. In the derivation of doppler formula, most high school and Undergraduate level textbooks have been imployed qualitative procedures. Since the procedure heavily depends on students' imaginative power to figure out the transmission, propagation, and reception of sound waves, studens might have difficulty to derive the doppler formula. In this research, a graphical method of the doppler formula derivation was used in order to overcome the difficulty. Two axes, distance and time, coordinates were employed and the movement of the source or the receiver were graphed in the coordinates. The period of signal transmission and signasl reception were determined geometrically on the graph: In this paper, three different cases were analysed and derived doppler formula respectively; (1) when the source moves with stationary receiver, (2) when the receiver moves with stationary source, (33) when the source and receiver moves together. The researchers expect that the method introduced in this study would provide a new way of teaching doppler effect in high school as well as in undergraduate lavel.
전주산업단지 및 주변지역 VOCs 및 악취물질 모니터링
김용문,박비오,고영삼,심재정,송병식,양고수 전북대학교 공학연구원 ( 구 전북대학교 공업기술연구소 ) 2002 工學硏究 Vol.33 No.-
Important main odorous compounds and VOCs(volatile organic compounds) possibly emitted from the Jeon-Ju Industrial Sites were identified and measured in amount through making air sampling over Jeon-Ju Industrial Sites and analyzing them with the sate of the art analytical instrument. Sampling sites were chosen 8 points by considering the industrial characteristics for the 1,2 Industrial Sites and 2 points for the 3 Industrial. Site Sampling times were two times, the first one was March. 2002 - April. 2002, and the second was May. 2002 - July. 2002. Canister sampling units and polyester bags were used to collect 6 liters air samples during 1hour or 3minutes for VOCs and polyester bags were used to sample 10 - 50 liters of air for 3 minutes depending on analytic characteristics of odor compounds. The important main VOCs were measured as acetone, ethyl benzene, n-hexane, m,p-xylene, toluene, M.E.K.(methyl ethyl ketone), isopropanol, ethyl acetate, o-xylene, n-butyl acetate, ethanol, benzene as in order of average concentration for the Industrial Sites. The main odorous compounds were COS, H2S, CS2, MM(methyl mercaptan), form aldehyde, acetaldehyde for the 1,2 Industrial Sites and COS, H2S, form aldehyde, acetaldehyde were measured as main species for the 3 Industrial Site. NH3 was measured as below the detection limit of the instrument. The concentrations of sulfide compounds for the 1,2 Industrial Sites were relatively higher than ones for the 3 Industrial Site. Among aldehydes, form aldehyde, acetaldehyde were detected very highly as 0.1- 1ppm over all the Industrial Sites.
김영삼,권재술 한국교원대학교 과학교육연구소 1996 청람과학교육연구논총 Vol.6 No.1
시공간 그래프는 고전약학의 운동학에서부터 많이 활용되어 왔다. 그것은 수식이 갖는 의미표현의 제약을 넘어서 그 의미를 좀더 구체적으로 시각화 할 수 있는 그래프의 특성때문일 것이다. 특수 상대성 이론의 운동학을 기술하는데도 이 그래프를 도입하여 고적역학적 그래프와 비교하여 그 특성을 먼저 이해한다면 보다 쉽게 특수 상대론적 운동학을 이해할 수 있을 것으로 생각한다. 따라서 본 연구는 상대론적 시공간 좌표계의 특성을 보다 근본적으로 이해할 수 있는 과정을 소개함으로써 특수 상대론적 시공간 개념에 대한 구체적인 이해와 이를 이용한 로렌츠 변환식의 유도에 연구의 목적을 두었다. The graphical method has been used widely in solving problems on classical kinematics because it has the advantage of visualiztion. The same advantage is expected in solving relativistic kinematics problems which are also closely related to motion. In this study, Lorentz transformation formula was derived using a spacetime graph only. In the derivation, the method of representing events in the two different coordinates and invariance of spacetime interval were used. Pure geometrical method was applied without using any algebraic method. If the students who are familiar with graphical representation of motion will understand this method more easily than the algebraic method which appear in most textbooks.