Maximally-Decimated Perfect Reconstruction Deinterlacer Banks Based on FCO-Sampling

Daisuke KITAGAWA,Takuma ISHIDA,Shogo MURAMATSU,Hisakazu KIKUCHI 대한전자공학회 2004 ITC-CSCC :International Technical Conference on Ci Vol.2004 No.7

Evaporation Heat Transfer and Pressure Drop Characteristics of R32 Inside a Multiport Tube with Microfins

Daisuke Jige,Shogo Kikuchi,Hikaru Eda,Norihiro Inoue,Shigeru Koyama 대한설비공학회 2018 International Journal Of Air-Conditioning and Refr Vol.26 No.2

This study investigated the evaporation heat transfer and pressure drop characteristics of R32 in a horizontal multiport tube consisting of rectangular minichannels with straight microfins. The heat transfer coefficient and pressure drop were measured for a mass velocity range of 50–400 kgm −2 s −1 and heat flux range of 5–20 kWm −2 at a saturation temperature of 15 ∘ C. The frictional pressure drop during an adiabatic two-phase flow was also measured for a mass velocity range of 50–400 kgm −2 s −1 and quality range of 0.1–0.9 at the same saturation temperature. The heat transfer coefficient increased with an increasing quality owing to the increase in forced convection. The dryout inception quality increased with the increase in mass velocity. The effects of heat flux on the heat transfer coefficient were small, except in a high-quality region. The heat transfer coefficient in a multiport tube with microfins was higher than that in a multiport tube without microfins in a high-quality region at a mass velocity of 200 kgm −2 s −1 and in a low-quality region at a mass velocity of 400 kgm −2 s −1. The effects of mass velocity and microfins on the frictional pressure drop were clarified. It is suspected that the effects of a microfin on the frictional pressured drop can be considered using the hydraulic diameter. The frictional pressure drop was shown to be in good agreement with previous correlations.

Aerosol model evaluation using two geostationary satellites over East Asia in May 2016

Goto, Daisuke,Kikuchi, Maki,Suzuki, Kentaroh,Hayasaki, Masamitsu,Yoshida, Mayumi,Nagao, Takashi M.,Choi, Myungje,Kim, Jhoon,Sugimoto, Nobuo,Shimizu, Atsushi,Oikawa, Eiji,Nakajima, Teruyuki Elsevier 2019 Atmospheric research Vol.217 No.-

<P><B>Abstract</B></P> <P>This study newly applies measurements from two geostationary satellites, the Advanced Himawari Imager (AHI) onboard the geostationary satellite Himawari-8 and the Geostationary Ocean Color imager (GOCI) onboard the geostationary satellite COMS, to evaluate a unique regional aerosol-transport model coupled to a non-hydrostatic icosahedral atmospheric model (NICAM) at a high resolution without any nesting technique and boundary conditions of the aerosols. Taking advantage of the unique capability of these geostationary satellites to measure aerosols with unprecedentedly high temporal resolution, we focus on a target area (115°E-155°E, 20°N-50°N) in East Asia in May 2016, which featured the periodic transport of industrial aerosols and a very heavy aerosol plume from Siberian wildfires. The aerosol optical thickness (AOT) fields are compared among the AHI, GOCI, MODIS, AERONET and NICAM data. The results show that both AHI- and GOCI-retrieved AOTs were generally comparable to the AERONET-retrieved ones, with high correlation coefficients of approximately 0.7 in May 2016. They also show that NICAM successfully captured the detailed horizontal distribution of AOT transported from Siberia to Japan on the most polluted day (18 May 2016). The monthly statistical metrics, including correlation between the model and either AHI or GOCI, are estimated to be >0.4 in 42–49% of the target area. With the aid of sensitivity model experiments with and without Siberian wildfires, it was found that a long-range transport of aerosols from Siberian wildfires (from as far as 3000 km) to Japan influenced the monthly mean aerosol levels, accounting for 7–35% of the AOT, 26–49% of the surface PM2.5 concentrations, and 25–66% of the aerosol extinction above 3 km in height over Japan. Therefore, the air pollutants from Siberian wildfire cannot be ignored for the spring over Japan.</P> <P><B>Highlights</B></P> <P> <UL> <LI> A high resolution model generally produces an observed aerosol distribution. </LI> <LI> Next-generation geostationary satellites are applied for aerosol model evaluation. </LI> <LI> Multiple measurement helped to understand the 4-dimensional aerosol structure. </LI> <LI> Siberian wildfires strongly affected the aerosol levels over Japan in May 2016. </LI> </UL> </P>

Usefulness of waist-to-height ratio in screening incident hypertension among Japanese community-dwelling middle-aged and elderly individuals

Kawamoto Ryuichi,Kikuchi Asuka,Akase Taichi,Ninomiya Daisuke,Kumagi Teru 대한고혈압학회 2020 Clinical Hypertension Vol.26 No.3

Background: The incidence of hypertension is increasing worldwide and obesity is one of the most significant risk factors. Obesity can be defined by various anthropometric indices such as body mass index (BMI), waist-to-hip ratio (WHpR), and waist-to-height ratio (WHtR). This study examined a range of anthropometric indices and their relationships with hypertension. Methods: This study included 768 men aged 70 ± 10 years and 959 women aged 70 ± 8 years from a rural village. The relationship between anthropometric indices (BMI, WHpR, and WHtR) and hypertension was examined using cross-sectional (baseline, N = 1727) and cohort data (follow-up, N = 419). Receiver operating characteristic (ROC) analysis was used to determine the predictive ability of obesity indices for hypertension in both genders. Logistic regression models were used to evaluate WHtR as a significant predictor of hypertension. Results: In the cross-sectional study, WHtR, BMI, and WHpR showed significant predictive abilities for hypertension in both genders, with WHtR showing the strongest predictive ability. Also, in the cohort study, WHtR showed a significant predictive ability for incident hypertension in both genders, and, for women, BMI as well as WHtR had also predictive ability. In the cross-sectional study, the optimal WHtR cutoff values were 0.53 (sensitivity, 44.3%; specificity, 80.2%) for men and 0.54 (sensitivity, 60.9%; specificity, 68.6%) for women. In the cohort study, the optimal WHtR values were 0.47 (sensitivity, 85.4%; specificity, 39.8%) for men and 0.51 (sensitivity, 66.7%; specificity, 58.2%) for women. Conclusions: The results suggest that WHtR is a useful screening tool for hypertension among Japanese middleaged and elderly community-dwelling individuals.

Serum uric acid to creatinine ratio is a useful predictor of all-cause mortality among hypertensive patients

Kawamoto Ryuichi,Kikuchi Asuka,Ninomiya Daisuke,Tokumoto Yoshio,Kumagi Teru 대한고혈압학회 2023 Clinical Hypertension Vol.29 No.-

Background Many of the existing research studies have shown that serum uric acid (SUA) is a predictor of renal disease progression. More recently, studies have suggested an association between renal function-normalized SUA and all-cause mortality in adults. This study aims to examine the association between the ratio of SUA to creatinine (SUA/ Cr) and all-cause mortality with a focus on hypertensive patients. Methods This study is based on 2,017 participants, of whom 916 were male (mean age, 67 ± 11 years) and 1,101 were female (mean age, 69 ± 9 years). All participants were part of the Nomura Cohort Study in 2002 (cohort 1) and 2014 (cohort 2), as well as the follow-up period (2002 follow-up rate, 94.8%; 2014 follow-up rate, 98.0%). We obtained adjusted relative risk estimates for all-cause mortality from a basic resident register. In addition, we employed a Cox proportional hazards model and adjusted it for possible confounders to determine the hazard ratio (HR) and 95% confidence interval (CI). Results Of the total participants, 639 (31.7%) were deceased; of these, 327 (35.7%) were male and 312 (28.3%) were female. We found an independent association between a higher ratio of SUA/Cr and a higher risk of all-cause mortality in female participants only (HR, 1.10; 95% CI, 1.02–1.18). The multivariable-adjusted HRs (95% CI) for all-cause mortality across quintiles of baseline SUA/Cr were 1.28 (0.91–1.80), 1.00, 1.38 (0.95–1.98), 1.37 (0.94–2.00), and 1.57 (1.03–2.40) for male participants, and 0.92 (0.64–1.33), 1.00, 1.04 (0.72–1.50), 1.56 (1.06–2.30), and 1.59 (1.06–2.38) for female participants. When the data were further stratified on the basis of age (< 65 or ≥ 65 years), body mass index (< 22.0 or ≥ 22.0 kg/m2), estimated glomerular filtration rate (< 60 or ≥ 60 mL/min/1.73 m2), and presence of SUAlowering medication, trends similar to those of the full population were found in all groups. Conclusion Baseline SUA/Cr is independently and significantly associated with future all-cause mortality among hypertensive patients.

High serum uric acid within the normal range is a useful predictor of hypertension among Japanese community-dwelling elderly women

Kawamoto Ryuichi,Ninomiya Daisuke,Akase Taichi,Asuka Kikuchi,Kumagi Teru 대한고혈압학회 2021 Clinical Hypertension Vol.27 No.1

Background: The risk associated with serum uric acid (SUA) levels when within the normal range is unknown. This study aims to examine whether SUA within the normal range is a predictor of hypertension. Methods: The subjects comprised 704 men aged 71 ± 9 (mean ± standard deviation) years and 946 women aged 70 ± 8 years recruited for a survey at the community based annual medical check-up. The main outcome was the presence of hypertension (antihypertensive medication and/or having SBP ≥140 mmHg and/or DBP ≥90 mmHg). Results: At baseline, 467 (66.3%) men and 608 (64.3%) women had hypertension. Comparing to lowest quartile in women (SUA-1, uric acid <4.1 mg/dL), the unadjusted odds ratios (ORs) [95% confidence interval (CI)] for hypertension of SUA-2 (4.1 to 4.7 mg/dL), SUA-3 (4.8 to 5.4 mg/dL), and SUA-4 (≥5.5 mg/dL) were 1.11 (0.78-1.59), 1.75 (1.20-2.55), and 1.89 (1.30-2.77), respectively. These associations were apparent even after adjustments for age, but ORs were attenuated after adjusting for all confounding factors. During a follow-up of 3.0 years, there were 35 (24.0%) hypertension cases in men and 51 (20.8%) in women. In women only, a significant association between increased SUA categories and incidence of hypertension was observed, and the multivariate-ORs (95% (CI) for incident hypertension of SUA-3 (4.5- 5.2 mg/dL) and SUA-4 (≥5.3 mg/dL) were 2.23 (0.81-6.11) and 3.84 (1.36-10.8), respectively. Conclusions: These results suggest that baseline SUA within the normal range could be an important predictor for incidence of hypertension in Japanese community dwelling elderly women.

Long-term Outcome of Asymptomatic Esophageal Eosinophilia

( Yugo Suzuki ),( Yorinari Ochiai ),( Daisuke Kikuchi ),( Mako Koseki ),( Kenichi Ohashi ),( Shu Hoteya ) 대한소화기학회 2024 Gut and Liver Vol.18 No.4

Background/Aims: Asymptomatic esophageal eosinophilia (aEE), characterized by eosinophil infiltration in the esophagus without clinical symptoms, has been reported as a precursor of eosinophilic esophagitis (EoE). Nevertheless, no report exists on the long-term clinical course of the disease. Therefore, this study aimed to investigate the long-term clinical course of aEE over 5 years, including the symptomatic conversion rate and the effect of treatments. Methods: We reviewed 28 patients with aEE who had been followed up for over 5 years with endoscopic monitoring. The basal characteristics of patients were compared with those of 58 patients diagnosed with EoE during the same period. Patients’ clinicopathological findings were collected and examined. Results: No significant differences in basal characteristics and histopathological findings were observed between the patients with aEE and those with EoE. The median follow-up duration was 64 months. Among the 28 patients with aEE, seven were treated with proton pump inhibitor or potassium-competitive acid blocker and the remaining 21 opted for follow-up with no medication. Among the treated patients, six (85.7%) exhibited endoscopic and pathologic improvements. Among the cases followed up without medication, the findings worsened in two (9.5%), improved spontaneously in seven (33.3%), and were unchanged in 12 (57.1%), and three (14.3%) developed symptoms at a mean time of 40 months. Symptoms developed in cases where endoscopic and pathologic findings remained unchanged or worsened during follow-up. Conclusions: Some patients with aEE had improved findings without treatment, whereas others developed symptoms, emphasizing the importance of long-term monitoring and individualized treatment decisions. (Gut Liver 2024;18:632-641)

Gastrointestinal Endoscopy-Assisted Minimally Invasive Surgery for Superficial Cancer of the Uvula

Hiroyuki Odagiri,Toshiro Iizuka,Daisuke Kikuchi,Mitsuru Kaise,Hidehiko Takeda,Kenichi Ohashi,Hideo Yasunaga 대한소화기내시경학회 2016 Clinical Endoscopy Vol.49 No.3

Previous studies reported that endoscopic resection is effective for the treatment of superficial pharyngeal cancers, as for digestive tract cancers. However, the optimal treatment for superficial cancer of the uvula has not been established because of the rarity of this condition. We present two male patients in their 70s with superficial cancer of the uvula, detected with upper gastrointestinal endoscopy. Both patients underwent surgical resection of the uvula under general anesthesia. The extent of the lesions was determined by means of gastrointestinal endoscopy by using magnifying observation with narrow-band imaging, enabling the performance of minimally invasive surgery. Endoscopic submucosal dissection was performed to achieve en bloc resection of the intramucosal carcinoma that had infiltrated the area adjacent to the uvula. Gastrointestinal endoscopists should carefully examine the laryngopharynx to avoid missing superficial cancers. Our minimally invasive treatment for superficial cancer of the uvula had favorable postoperative outcomes, and prevented postoperative loss of breathing, swallowing, and articulation functions.

Lymphadenectomy issues in endometrial cancer

Yosuke Konno,Hiroshi Asano,Ayumi Shikama,Daisuke Aoki,Michihiro Tanikawa,Akinori Oki,Koji Horie,Akira Mitsuhashi,Akira Kikuchi,Hideki Tokunaga,Yasuhisa Terao,Toyomi Satoh,Kimio Ushijima,Mitsuya Ishika 대한부인종양학회 2021 Journal of Gynecologic Oncology Vol.32 No.2

Objectives: This review aims to introduce preoperative scoring systems to predict lymphnode metastasis (LNM) and ongoing clinical trials to investigate the therapeutic role oflymphadenectomy for endometrial cancer. Methods: We summarized previous reports on the preoperative prediction models forLNM and evaluated their validity to omit lymphadenectomy in our recent cohorts. Next, wecompared characteristics of two ongoing lymphadenectomy trials (JCOG1412, ECLAT) toexamine the survival benefit of lymphadenectomy in endometrial cancer, and described thedetails of JCOG1412. Results: Lymphadenectomy has been omitted for 64 endometrial cancer patients who met low risk criteria to omit lymphadenectomy using our scoring system (LNM score) and no lymphaticfailure has been observed. Other two models also produced comparable results. Two randomizedphase III trials to evaluate survival benefit of lymphadenectomy are ongoing for endometrialcancer. JCOG1412 compares pelvic lymphadenectomy alone with pelvic and para-aorticlymphadenectomy to evaluate the therapeutic role of para-aortic lymphadenectomy for patients atrisk of LNM. For quality assurance of lymphadenectomy, we defined several regulations, includinglower limit of the number of resected nodes, and submission of photos of dissected area toevaluate thoroughness of lymphadenectomy in the protocol. The latest monitoring report showedthat the quality of lymphadenectomy has been well-controlled in JCOG1412. Conclusion: Our strategy seems reasonable to omit lymphadenectomy and could begeneralized in clinical practice. JCOG1412 is a high-quality lymphadenectomy trial in terms ofthe quality of surgical procedures, which would draw the bona-fide conclusions regarding thetherapeutic role of lymphadenectomy for endometrial cancer.

A Method for Reducing the Number of Metal Layers for Embedded LSI Package

오시마다이스케,모리켄타로,나카시마요시키,키쿠치카츠미,야마미치신다로,Ohshima, Daisuke,Mori, Kentaro,Nakashima, Yoshiki,Kikuchi, Katsumi,Yamamichi, Shintaro The Korean Microelectronics and Packaging Society 2010 마이크로전자 및 패키징학회지 Vol.17 No.4

We have successfully demonstrated a high-pin-count and thin embedded-LSI package to realize next generation's mobile terminals. The following three design key points were applied: (i) Using Cu posts, (ii) Using the coreless structure, (iii) Using a Cu plate as the ground plane. In order to quantitatively determine the contribution of the three points, the five-stage process for reducing the number of metal layers is described by means of the electrical simulation. The point-(i) and (ii) are effective from the viewpoint of the power integrity (PI); that is, these points play important roles in reducing the number of metal layers, and especially the point-(ii) contributes at least twice as the point-(i). The point-(iii) is not effective in the PI, but has a few effects on the signal integrity (SI). For reducing the number of metal layers, we should, at first, pay attention whether the PI characteristics fulfill the specification, and then we should confirm the SI characteristics.