방사성고화체로부터의 $^{60}$ Co, $^{137}$ Cs 침출에 대한 표준시험법의 상호비교

김기홍,유영걸,정경기,홍권표,이락희,정의영,고덕준,김헌,Kim, Ki-Hong,Ryu, Young-Gerl,Chung, Kyung-Ki,Hong, Kwon-Pyo,Lee, Nak-Hee,Jeong, Yi-Yeong,Koh, Duck-Joon,Kim, Heon 한국방사성폐기물학회 2003 방사성폐기물학회지 Vol.1 No.1

IAEA, FT-04-020 및 ANS 16.1의 침출시험법을 각각 수행하여 얻은 시험결과를 이용하여 상호 비교 평가하였다. 붕산을 함유한 파라핀 및 시멘트 고화체에서의 $^{60}$Co 과 $^{137}$Cs의 ANS 16.1의 침출지수는 6이상이었으나 고화매질과 탈염수의 종류에 따라 상반되는 침출거동을 보였다. 침출수로 합성해수와 탈염수를 사용하였을 경우 $^{60}$Co는 시멘트 고화체에서는 합성해수, 파라핀 고화체에서는 탈염수에서 침출이 높았다. 반면에 $^{137}$Cs의 침출정도는 시멘트에서는 탈염수, 파라핀에서는 합성해수에서 높았다. $^{60}$Co의 침출분율은 시멘트 고화체에서 IAEA > ANS > FT의 순으로 높았으며, 반대로 파라핀고화체에서는 이의 역순이었다. IAEA, FT-04-020, and ANS 16.1, standard leaching test methods, were evaluated comparatively with their test results. Leaching index of $^{60}$ Co and $^{137}$ Cs by ANS 16.1 method for waste forms of paraffin and cement were above 6.0. Their leaching behavior were depending on the type of matrix and leachant. Leachability of $^{60}$ Co for cement waste form was higher in simulated seawater than do-mineralized water, and was higher in de-mineralized water for paraffin waste form. leachability of $^{60}$ Co was contrary to $^{137}$ Cs. Cumulative fraction leached of $^{60}$ Co was higher in order or IAEA > ANS > FT in a cement waste form.

광선각화증, 보웬병, 편평상피세포암에서 Ki-67, Cyclin A, p53, p16의 발현 양상

이효진 ( Hyo Jin Lee ),신동훈 ( Dong Hoon Shin ),최종수 ( Jong Soo Choi ),김기홍 ( Ki Hong Kim ) 대한피부과학회 2012 대한피부과학회지 Vol.50 No.4

Background: Actinic keratosis (AK) and bowen`s disease (BD) are pre-cancerous diseases, and are regarded as an early squamous cell carcinoma (SCC). AK and BD can be progressed into SCC. In this process, tumor suppressor and cell proliferative proteins may play important roles. Objective: To investigate the differences of expression patterns of the immunohistochemical (IHC) staining and useful markers for differential diagnosis in AK, BD and SCC. Methods: Biopsy had proven 17 cases of AK, 20 cases of BD and 17 cases of SCC, which were all selected. IHC staining for Ki-67 and cyclin-A, as cell proliferative markers, p53 and p16 as tumor suppressor markers, were performed. Labeling index (LI) and distribution pattern of IHC expressions were measured. Results: LI of Ki-67 in AK, BD and SCC were 30.6%, 60.2% and 54.8%, respectively. LI of cyclin-A in AK, BD and SCC were 9.2%, 24.4% and 24.1%, respectively. LI of p53 in AK, BD and SCC were 20.7%, 37.9%, and 39.9%, respectively. LI of p16 in AK, BD and SCC were 10.6%, 38.3% and 39.9%, respectively. Lower 1/3 was the most frequent distribution pattern in AK in all IHC stains, full thickness lower 2/3 were the most frequent distribution pattern in BD and SCC in all IHC stains. Conclusion: LI and distribution pattern of Ki-67, cyclin-A, and p16, as well as the distribution pattern of p53 may be useful markers to differentiate AK from BD and SCC. Higher degree and full-thickness distribution pattern IHC expressions in all stains may be helpful in the diagnosis of BD, rather than AK. (Korean J Dermatol 2012;50(4):290∼298)

키토산으로 표면처리된 인공치아의 충격전달에 관한 연구

김기홍,이용찬,조병욱,권익찬,최귀원,배태수,Kim, Ki-Hong,Lee, Yong-Chan,Cho, Byoung-Ouck,Choi, Kui-Won,Kwon, Ick-Chan,Bae, Tae-Soo 대한구강악안면외과학회 2001 대한구강악안면외과학회지 Vol.27 No.1

With the object of providing a temporary artificial periodonal ligament-like membrane around the dental implant, 10 Branemark type implants were coated with commercially available chitosan(Fluka Co., Buchs, Switzerland) which has a molecular weight of 70,000 and 80% deacetylation degree. Once this bioactive hydrophillic polymer(chitosan) contacts with blood or wound fluids, it becomes swollen and penetrates into the adjacent cancellous bone. Thus the interface between implant and surrounding bone is completely filled with chitosan. This tight junction in early healing phase enhances primary stability. The chitosan coated dental implants were implanted into the fresh patella bones from porcine knees, since the thickness of cortical bone is relatively even and their cancellous structure is homogenous. To test the shock absorbing effect, 1mm delta-rogette strain gage was installed behind the implant. The results showed 1. The principal strain peak value directed to the impact of coated implant was 0.064 0.018(p<0.05) and that of uncoated implant was 0.095(0.032 p<0.05). 2. The peak time delay of coated implant was 0.056sec(0.011 p<0.05) and that of uncoated implant was 0.024sec(0.009 p<0.05). It can be reasoned from this results that the chitosan coating has a shock absorbing effect comparable with a temporary artificial periodontal ligament.

물류 종사자의 성격유형이 물류생산에 미치는 영향

김기홍,Kim, Ki-Hong 대한안전경영과학회 2017 대한안전경영과학회지 Vol.19 No.3

In order to increase the productivity of the logistics center and transportation, we try to articulate the priority ranking factors of the productivity influenced by the personality of the field workers (logistics center workers) and functional workers (drivers) via the AHP technique Individual personality was studied by applying the Big 5 model of psychological factors (openness, Conscientiousness, extroversion, Agreeableness, neuroticism). In this paper, extraversion was critically analyzed as a priority factor. A trait of extroversion is a strongly active and individual personality. In this study, the field workers are logistics center workers and the functional workers are drivers. They are interactively influenced in the In & Out operation. For example, when it comes to 'up and down work' and 'inspection work', the functional workers perform 'up and down work' and 'delivery work' and the field workers perform 'inspection work'. Stressing on the respective work has an affect on work productivity. Inspection workforce has something to do with inventory management. Functional workforce affects the delivery workforce. Delivery work is positively correlated with customer satisfaction. Nevertheless, as a result of research, extrovert personality that has something to do with an energetic activity would not affect on the implementation of their operation. In addition, personal extraversion of workers and drivers in the warehouse can have a significant impact on job commitment and productivity improvement.

히르쉬스프룽병의 병변부위에서 nNOS 발현

김기홍,김한성,이성철,Kim, Ki-Hong,Kim, Han-Seung,Lee, Seong-Cheol 대한소아외과학회 2005 소아외과 Vol.11 No.1

Abnormal distribution of enteric nerves such as adrenergic, cholinergic and non-adrenergic non-cholinergic nerves (NANC) may cause the failure of relaxation at the involved bowel segment in Hirschsprung's disease (HD). Nitric oxide (NO) is a major inhibitory NANC neurotransmitter in the gastrointestinal tract. NO is synthesized by activation of nNOS (neuronal nitric oxide synthase) in the intramural ganglion cells and regulates bowel movement. To assess the distribution of nNOS in HD, immunohistochemical staining to nNOS was utilized on paraffin embedded specimens. Ten control colon specimens were tested for feasibility of staining. Immunohistochemisrty was done on ganglionic colon as well as aganglionic segment of 15 patients with HD. nNOS immunoreactivity was observed in the neuronal cells, small cells and nerve fibers in the muscle layer and submucosal neuronal cells of control specimens. This finding was also observed in the ganglionic segments of HD. But, there was no nNOS immunoreactivity in aganglionic segments of HD. In conclusion nNOS immunohistochemical staining of paraffin embedded specimen is feasible and reliable. And the results suggest that the relaxation failure of the aganglionic bowel in HD is related to the absence of nNOS containing cells and nerve fibers.

오자연종환(五子衍宗丸)이 노화유발(老化誘發) 흰주의 항산화능(抗酸化能)에 미치는 영향(影響)

김기홍,정국훈,김광호,고성규,Kim, Ki-Hong,Ding, Guo-Xun,Kim, Kwang-Ho,Ko, Seong-Gyu 대한예방한의학회 2005 대한예방한의학회지 Vol.9 No.1

Objectives : Ojayeonjonghwan(五子衍宗丸) is composed of Polygonum multiflorum THUNB, and some medical herbs that are known as formula of senescence delay effects. The purpose of this study is to investigate th effect of Ojayeonjonghwan on antioxidant enzyme activities, such as Thiobarbituric acid reactive substance(TBARS), Superoxide dismutase(SOD), Catalase(CAT), Glutathione preoxidase (GSH-px) in rat erythrocytes and blood plasma. Methods : Sprague-Dawley rats were divided into 3 groups, Normal group (supplied enough water and feeds only, Normal Group), D-galatose administered group(injected D-galatose 50mg/kg, 1time/day for 6 weeks, Control Group) and Ojayeonjonghwan administered group (D-galactose 50mg/kg and Ojayeonjonghwan extracts 245.0mg/200g 1time/day for 6 weeks, OJY Group). Rats were sacrificed and TBARS, SOD, CAT, GSH-px, Plasma total lipid, Plasma triglyceride and cholesterol were measured in rat erythrocytes and blood plasma. Results : TBARS in plasma concentration of OJY group was significantly lower than that of control group. Red blood cell(RBC) SOD activity of OJY group was significantly higher than that of control group(F=16.057, p=0.0001, ANOVA test), RBC GSH-px activity of OJY group was increased(F=4.271, p=0.034, ANOVA test). RBC catalase activities of all experimental group were not significantly different. Total lipid and triglyceride concentration in plasma of all experimental groups were not significantly different. Total cholesterol concentrations in plasma of OJY group were significantly lower than those of control group(F=4.387, p=0.032, ANOVA test). Conclusions : According to the above results, it is considered that Ojayeonjonghwan is effective in inhibiting lipid peroxidation and increasing antioxidative enzyme activities in D-galactose induced aging rat.

한국산(韓國産) 야조(野鳥)에 기생(寄生)하는 선충류(線蟲類)에 관한 연구(硏究)(제1보(第一報))

김기홍,임한종,Kim, Ki-Hong,Rim, Han-Jong 한국농촌의학.지역보건학회 1990 농촌의학·지역보건 Vol.15 No.1

한국산 야조에 기생하는 윤충류에 관한 연구는 주들(1973)에 의해 흡충류 일부만이 기록되어 있을 뿐 그 외에는 거의 분류학적인 연구가 되어 있지 않은 실정이다. 따라서 저자 등은 1990년 1월부터 1990년 3월에 걸쳐 경기도, 강원도 및 경북등지에서 채집한 야조 5종으로부터 기생윤충류를 조사하였으며, 수집된 윤충류중 일단 선충류 3종을 분류, 기재하였다. 채집된 야조의 종류는 Garrulus glandarius brandtii, Cyanopica cyanus koreensis, Otus scops stictonotus, Asia flammeus flammeus, Buteo buteo japonicus 등이다. 동정된 선충류의 종류는 Acuariidae과의 Dispharynx nasuta(male & female), Spiruridae과의 Excisa excisa(male & female), Fillariidae과의 Diplotriaena manipoli(male & female) 등 3종이며, 이들 3종은 모두 우리 나라에서의 처음 기록되는 종들이다. From five species of wild birds which were collected in the period of January, 1990~March, 1990, three species of nematodes were identified. The three species were Dispharynx nasuta(Rudolphi, 1819) in Spiruridae and Diplotriaena manipoli Chu, 1931 in Fillaridae. They are the first recording species in Korea and the morphological characters of each species(male & female) are described.

${In_{0.5}}({Ga_{1-x}}{Al_x})_{0.5}P$/GaAs 이중 이종접합 구조에 대한 표면 광전압 특성

김기홍,최상수,배인호,김인수,박성배,Kim, Ki-Hong,Choi, Sang-Soo,Bae, In-Ho,Kim, I n-Soo,Park, Sung-Bae 한국재료학회 2001 한국재료학회지 Vol.11 No.8

Surface photovoltage spectroscopy was used to study $In_{0.5}(Ga_{1-x}Al_x)_{0.5}P/GaAs$ grown by metalorganic chemical vapor deposition(MOCVD). Energy gap related transition in GaAs and $In_{0.5}(Ga_{1-x}Al_x)_{0.5}P$ were observed. By measuring the frequency dependence of $In_{0.5}(Ga_{1-x}Al_x)_{0.5}P/GaAs$, we observed that SPV line shape does not chance, whereas the amplitude change. This results is due to the difference in the lifetimes of the photocarriers in GaAs and in $In_{0.5}(Ga_{1-x}Al_x)_{0.5}P$. We also have evaluated the parameters that describe the temperature dependences of the band gap. Metalorganic chemical vapor deposition (MOCVD)으로 성장한 $In_{0.5}$ ($Gal_{1-x}$ $Al_{x}$ )0.5P/GaAS 이중 이종접합 구조의 특성을 표면 광전압 (surface Photovoltage ; SPV) 측정으로 연구하였다. $In_{0.5}$($Gal_{1-x}$ $Al_{x}$ )0.5P/GaAS 이중 이종접합 구조의 SPV 측정값을 Lorentzian 피팅한 띠 간격에너지 ($E_{0}$ ) 값과 조성비 (x)로 구한 이론 값이 잘 일치하였다. 그리고 변조 주파수 의존성을 측정한 결과 SPV 신호의 형태는 변하지 않고, 신호의 크기만이 변하는 것은 광 조사에 따른 전기적 상태의 과도 현상에 따른 것이고, GaAs와 InGaAlP의 특성시간의 차이는 광 캐리어의 수명의 차이로 분석된다. 그리고 온도 의존성 측정으로 $In_{0.5}$ /($Gal_{1-x}$ $Al_{x}$ )0.5P/GaAS 이중 이종 접합 시료의 균일한 변형분포와 계면상태가 양호함을 알 수 있었다.

Two digenean parasites infestations of sea bass, Lateolabrax japonicus(Cuvier), form the Korean southern sea

김기홍,최은석,지보영,허성회,Kim, Ki-Hong,Choi, Eun-Seok,Ji, Bo-Young,Huh, Sung-Hoi 한국어병학회 1997 한국어병학회지 Vol.10 No.1

한국 남해안에서 채집된 농어의 장에서 흡충류 2종-Tergestia laticollis, Biovarium cryptocotyle-이 검출되었다. T. laticollis는 구흡반의 주위로 거꾸로된 왕관모양의 두엽들과 인두주변에 6쌍의 판자모양 구조물 및 충란의 크기 등에 의해 다른 종들과 구분되어졌으며, B. cryptocotyle의 가장 특징적인 점은 난소가 2분지된 점이었다. 이 두 종은 우리나라에서 처음 기록되는 미기록종들이었으며, 농어는 T.laticollis의 새로운 종숙주임이 금번 연구를 통해 밝혀졌다. Two species of digeneans, Tergestia laticollis and Biovarium cryptocotyle, were collected from the intestine of sea basses(Lateolabrax japonicus) captured at the Korean Southern Sea. T. laticollis was characterized by having cephalic lobes around oral sucker, six muscular flanges on each lateral surface at level of pharynx, and species-specific egg size. The most outstanding characteristic of B. cryptocotyle was two-divided ovary. These two digenean species were the first recording species in Korea and L. japonicus was the newly recording host for T. laticollis.

배지에 착색을 보인 Trichophyton rubrum에 의한 체부백선

김기홍,박용묘,김종철,최종수 ( Ki Hong Kim,Yong Myo Park,Jong Cheol Kim,Jong Soo Choi ) 대한피부과학회 1991 대한피부과학회지 Vol.29 No.4