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Ken Woo,Andrew Padalhin 대한의학레이저학회 2023 MEDICAL LASERS Vol.12 No.1
Cancers of major organs and their treatment with chemotherapeutic agents can be difficult and challenging, both because of the disease itself, and also because of the accompanying side effects of the treatment. Recent studies in cancer biology have revealed that cancer cells have higher levels of reactive oxygen species (ROS). ROS play a dual role in physiological and pathological conditions of the human body. It is well known that ROS are engaged in many cellular activities for the preservation of cellular homeostasis. While both normal and cancer cells maintain specific levels of ROS, excess ROS leads to increased oxidative stress linked to cellular damage and potentially cell death. Emergent technologies like plasma therapy and photobiomodulation (PBM), have demonstrated their capabilities of increasing intracellular ROS levels, thus, gaining recognition as prospective cancer treatments. This review aims to summarize the effects of plasma and PBM on the ROS levels of cells as observed in previous studies and evaluate their potential to be developed as treatments for cancer.
Ken Woo,Celine Abueva 대한의학레이저학회 2022 MEDICAL LASERS Vol.11 No.3
Mesenchymal stem cells (MSCs) are multipotent stromal cells that can differentiate into many other cell types typically isolated from adult tissue sources. The therapeutic potential of MSCs is considerable in regenerative medicine and has advanced over the years. Consequently, methods and tools that improve the therapeutic efficacy of MSCs have also been devised and utilized. Recent strategies used to enhance the therapeutic efficacy of MSC include photobiomodulation (PBM), which can increase proliferation and enhance differentiation into target cell types. PBM is a non-thermal, non-invasive method that utilizes light from coherent or non-coherent sources to influence metabolic activity at the cellular level and has been found to increase cell proliferation and migration in vitro, in vivo, and in clinical studies. However, little is known of the mechanism responsible for the effects of PBM on MSCs or its potential as an adjunctive treatment, which obscures appreciation of its regenerative applications. This review summarizes reports on the effects of PBM on different MSCs and provides perspectives on the ability of PBM to improve the therapeutic efficacy of MSCs in regenerative medicine.
결정질 Si Wafer의 thickness에 따른 열 전도 특성에 관한 연구
우성철(Woo Sung-Cheol),정태희(Jung Tae-Hee),윤나리(Yoon Na-Ri),강기환(Kang Ki-Hwan),안형근(Ahn Hyeung-Ken),한득영(Han Deuk-Young) 한국태양에너지학회 2010 한국태양에너지학회 학술대회논문집 Vol.2010 No.11
Now days, the cost of raw materials has been rising. And the solar industry worry about production cost. Many companies want to decrease unit cost of wafer. One way of solution is thin silicon solar cell. But thin solar cells are damaged in the physical thermal at tabbing process. The best way is tabbing in lowest soldering temperature and appropriate adhesive. In this paper, a study on heat conduction characteristics by thickness of silicon wafer in same setup with production process. The target is optimization of soldering temperature. The test was known back face temperature at tabbing with hot air and thin wafers conducted more heat flux. It give damage by heat shock. Single crystal wafer and multi crystal wafer by 200㎛,170㎛, 150㎛ thickness was test. In addition, heat transfer process was a visual representation of the simulation by Ansys tool.