경피전기신경자극의 동통억제효과에 대한 실험적 연구

송형근,이상호,계기성,유종만 大韓小兒齒科學會 1995 大韓小兒齒科學會誌 Vol.22 No.1

The purpose of this study was to investigate the effect of electrical anesthesia induced by transcutaneous electrical nerve stimulation on inhibition of the pain response evoked by noxious electrical stimuli in teeth and gingiva. The experiment was carried out on anesthetized dogs. Left digastric muscle was exposed and wire electrodes were inserted into the muscles to record E.M.G.. Bipolar stimulating electrodes were inserted into the tooth of canine and the palatal area of gingiva. Noxious electrical stimuli were delivered to the tooth and the gingiva by electric stimulator(GrassTM, USA) under electronic anesthesia induced by transcutaneous electrical nerve stimulation device with frequency of 50㎐. The E.M.G. of jaw opening reflex at digastric muscle was measured by the osciloscope and the audiometer connected to amplifier(A-M system, 1700, USA) at different intensity of electronic anesthesia of 1 volt, 4 volt, and 10 volt. The pain threshold and the inhibitory rate of pain via E.M.G. of digastric muscle were analysed statistically with paired t-test adn χ2-test. The obtained results were as follows ; 1. Transcutaneous electrical nerve stimulation with intensity of 1 volt and 4 volt increased the pain threshold 9.4% and 18.6% in teeth and 14.3% and 32.1% in gingiva respectively, but that of 10 volt did not change or reduce the pain threshold. 2. Transcutaneous electrical nerve stimulation with intensity of 1 volt, 4 volt, and 10 volt showed the inhibitory effect of pain of 10.5%, 15.0% and 4.6% in teeth, and 18.2%, 23.4%, and 19.3% in gingiva respectively when noxious electrical stimulation was inserted 1.5 times higher than the pain threshold. Transcutaneous electrical nerve stimulation with intensity of 10 volt did not show inhibitory effect of the pain response as that of 1 volt and 4 volt. 3. The pain threshold in gingiva was increased higher by transcutaneous electrical nerve stimulation than it was in teeth, and the inhibitory effect of the pain in gingiva was also increased higher than it was in teeth. In regard to above results, inhibitory effects of pain induced by transcutaneous electrical nerve stimulation was not so high as to replace the role of drug anesthesia wholly. The technique of reducing pain induced by transcutaneous electrical nerve stimulation itself, was needed to develop to have better anesthetic or analgesic effect and less discomfort during anesthetic procedure.

복어중독에 의한 가사 상태에서 소생한 1예

송승찬,신진호,강석우,박경남,최호순,박근태,문희식,기춘석,이성희,윤병철,노우균,조균석,이민호 大韓應急醫學會 1998 대한응급의학회지 Vol.9 No.3

Tetrodotoxin is a neurotoxin produced by about 90 species of puffer fish and causes paralysis of central nervous system and peripheral nerves by blocking the movement of all monovalent cation. Ingestion of tetrodotoxin produces clinical manifestations such as paresthesias(within 10-45 min), vomiting, lightheadedness, salivation, muscle twitching, dysphagia, difficulty in speaking, convulsion and death that expressed by cardiopulmonary arrest with loss of brain stem reflex sometimes. Tetrodotoxin prevents or delays ischemia induced neuronal death by way of following 3 mechanisms. Firstly, it reduces the energy demand of the brain tissues. Secondly, it delays or even prevents anoxic depolarization. Finally, it deminishes ischemia induced cell swelling and cerebral edema. We report a case of puffer fish poisoning which presented with cardiopulmonary arrest and loss of brain stem reflex, but completely recovered by aggressive cardiopulmonary resuscitation.

접착용 세멘트내에 함유된 불소가 활택면 법랑질에 미치는 영향에 관한 연구

김용기,송호환 大韓小兒齒科學會 1995 大韓小兒齒科學會誌 Vol.22 No.1

The prevalence of caries in children is still high in general, especially when they are inthe course of orthodontic treatment. Although the direct bonding of orthodontic attachments has become more popular, orthodontic bands are still widely used in practices. Enamel demineralization occuring beneath orthodontic bands is one that plagues clinicians. The use of fluoriode as an anticariogenic agent is well proven, and its incorporation into orthodontic cements would seem to be a logical step. In this study, fluoride uptake on the smooth surface of enamel and anticariogenic effect by several luting cements were compared and analyzed. The enamel surface covered with fluoride containing luting cement group (GroupⅠ,Ⅱ,Ⅲ) showed superior uptake of fluoride to non-fluoride group (Group Ⅳ). Among the tested fluoride containg groups, glass ionomer cement (Group Ⅲ) showed the highest value in fluoride uptake and two polycarbostlate cements showed no significant differense each other. Histological results from fluoride containg groupd showed general similarity in that artificial lesions were produced at some distances away from the cement-window marsin revealing the anticariogenic effect of fluofied in them. The results of the present study strongly suggest the use of fluoride containg luting cements in orthodontic patients for the maximum protection of enamel from possible demineralization.

접형동, 뇌하수체병변 수술을 위한 경비중격접형동 접근법에 대한 연구

장철호,송영창,곽기용 圓光大學校 醫科學硏究所 1996 圓光醫科學 Vol.12 No.1

Early attempts to remove pituitary tumors included a transcranial approach that was impeded by numerous anatomic obstacles like the cavernous sinus, the carotid artery, and the optic chiasm. Nearly every pituitary tumor can be exposed and removed through the nasal septum. Advances in physics and biochemistry have supported substantial improvements in diagnosis and management so that transseptal transsphenoidal approach is one of the most predictable operations performed for pituitary tumor. The sublabial transseptal approach(Hardy) should access to the septal spaces and the sphenoid sinus, working entirely under the lip. However, working into the nose from a low angle under the canopy of the orbicularis oris muscle does restrict visibility at the point surgeon needs it most, over the premaxillar wings. In 1990, we began performing the entire septal dissection through a septal hemitransfixation incision, saving the sublabial incision until later in the operation when we wanted to insert the nasal speculum. This modified approach improved our ability to elevate the mucoperichondrium from the anterior-inferior regions of the septum in the premaxillary region without perforation. The nasal spine ceased to be an issue because it was no longer in the way. We studied 10 cases of modified transseptal transsphenoidal approach to pituitary tumor and other lesions during a period of 6 years between September. 1990 and October, 1996.

천연가스 사용 난방 및 산업보일러의 NOx와 CO 배출계수 산정 연구

장영기,최상진,김관,송기봉,김호정,정봉진 한국대기환경학회 2004 한국대기환경학회지 Vol.20 No.5

This study was conducted for developing the emission factors of nitrogen oxide(NOx) and carbon monoxide (CO) from the combustion boilers burning liquefied natural gas (LNG). These emission factors were compared with those of U.S. EPA and European Environment Agency (EEA). NOx and CO concentration in the flow gas were measured using Kane-May, KM9106 and Thermo Environmental Instruments Inc., 42C-HL. Measurement were conducted at thirty industrial and commercial LNG boilers. Emission factors were calculated on the basis of fuel consumption (kg-pollutant/㎥-fuel burned). NOx concentration at industrial boiler was 14~125 ppm and it was measured as 35~125 ppm at commercial boiler. NOx emission factors of industrial boiler and commercial boiler were 1.84kg/㎥ and 2.09kg/㎥, respectively. NOx emission factor of commercial boiler was higher than that of industrial boiler. The NOx emission factors estimated in this study were lower than those of U.S. EPA and higher than those of EEA. Average CO emission factor of industrial boiler was 0.65 kg/㎥ and at commercial boiler it was 0.70kg/㎥, CO emission factor at industrial boiler was lower than that at commercial boiler.

수종의 복조재에 대한 성견치수의 조직학적반응

김용기,송호환 大韓小兒齒科學會 1997 大韓小兒齒科學會誌 Vol.24 No.3

The purpose of the present study was to analyze the pulpal tissue reactions to several capping materials. 8 adult Mongrel dogs and 4 different capping materials (GⅠ: Calcium hydroxide, GⅡ: Bonding resin, GⅢ : Glass ionomer liner, GⅣ: Bioactive ceramic) wereused in the study. The results can be summarized as follows: 1.The formation of hard tissue barrier was observed to begin after 2 weeks in all groups with various forms or positions. 2.According to the result of statistical analysis, GⅠand GⅣ showed significantly higher degree of inflammation than GⅡ,GⅢ in 1-weeks in samples(p<.05). And in 2-week samples, GⅠ showed higher degree of inflammation than GⅡ,GⅣ with statistical significance(p<.05) However,these inflammatory reactions have gradually dimiished with time resulting in negligible difference between groups. 3.No bacterial penetration was observed in any group. 4.Hard tissue formation was evident in all groups after 2 weeks regardless of material type in this experiment. Conclusion can be drawn from the above-mentioned results that the perfect marginal sealing after pulp capping procedure is thought to be the most important factor in determining the propgnosis of direct pulp capping.

특발성 좌심실빈맥(Idiopathic Left Ventricular Tachycardia)의 성공적인 전극도자절제술을 위해 단극전기도(Unipolar Electrogram)가 유용한가?

최기준,남기병,강덕현,홍명기,송재관,김재중,박성욱,박승정,박종훈,김유호 대한순환기학회 2000 Korean Circulation Journal Vol.30 No.4

축산시설에서 발생되는 악취의 축종별 특성에 대한 설문조사

장영기,송기봉,김호정,유용희 한국환경영향평가학회 2004 환경영향평가 Vol.13 No.1

At Recent the number of livestock is rapidly increased and the scale of farm has changed to large operations in Korea. So the odors frcm livestock feeding operations have increased and become major environmental problem. The odor emission are dependent on the types of manure management system and the meteorological factors. This report presents the results of a questionnaire on the odor characteristics from livestock facilities for the beef, dairy, swine and poultry. It is founded that the impact by odors from the facilities for swine and poultry is higher than cow and dairy, and the odor intensity at morning is higher than other times.

우각차단을 동반한 급사증후군 2예

박상선,남기병,최기준,송재관,김재중,박승정,박종훈,김유호 대한순환기학회 2000 Korean Circulation Journal Vol.30 No.5

Chinese hamster 난소세포에서 수용성 니켈에 의해 특징적으로 발현되는 유전인자들의 빠른 분석에 관한 연구

성근제,이상한,우기민,송호연,조만희 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.2

니켈에 의한 암 발생기전 및 세포 독성기전을 이해하고 니켈에 의해 발현에 변화를 보이는 유전자들을 검출하기 위하여 니켈이 포함된 배지에서 배양된 Chinese hamster난소 세포부터 mRNA differential display 분석을 시행하였다. 본 연구에서는 동위원소나 DNA염기서열 분석용 젤을 사용하는 기존의 방법 대신에 훨씬 빠르고, 다루기 쉽고 안전성을 지닌 변형된 기법을 개발하여 적용하였다. 니켈에 의해 발현에 변화를 보이는 cDNA fragments들을 10% polyacrylamide mini젤상에서 분리 및 클로닝한 다음, DNA염기 서열 분석과 GenBank Blast search 프로그램을 이용하여 상동성 조사를 하였다. Reverse Northern blot을 이용하여 발현에 변화가 있는 cDNA들을 재확인한 결과, 검사된 19 cDNAs 들중 총 9종에서 발현의 변화를 보였으며, 이 중 3종은 니켈에 반응하여 발현에 증가를 보였고, 반면에 6종은 발현이 감소하였다.