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      • Successful Resection for Huge Combined Hepatocellular- Cholangiocarcinoma after Portal Vein Embolization - A Case Report

        ( Po-chih Yang ),( Hsin-chieh Huang ),( Kai-wen Huang ) 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1

        Aims: Combined hepatocellular-cholangiocarcinoma (cHCC-CC) is a rare primary hepatic cancer with poor prognosis. Aggressive surgical planning with complete resection of cHCC-CC plays an important role in treatment. We presented one case of successful resection of huge cHCC-CC after portal vein embolization (PVE). Methods: This is a 46-year-old man with alcoholic liver cirrhosis. CT scan showed one 10cm infiltrative tumor in right liver with right anterior portal venous tumor thrombosis enhanced in arterial phase and washed out in portal venous phase. Regional enlarged lymph nodes is also noted. Under the preoperative diagnosis of HCC, right hepatectomy is planned. CT volumetry showed future liver remnant(FLR) is 480ml, 38.5% of standard liver volume. The ideal percentage of FLR in cirrhotic liver is more than 40% in our institution. Because of tumor thrombosis with total occlusion in right anterior portal pedicle, we performed PVE to right posterior portal vein for inadequate FLR. Two weeks after PVE, left liver enlarged from 480ml(38.5%) to 620ml(49.7%). There was no complication during PVE. Results: Right hepatectomy and regional lymph node dissection were performed two weeks after PVE. The post-operative course was smooth without any evidence of hepatic insufficiency. Pathology reported combined hepatocellular-cholangiocarcinoma but no malignant lymph nodes. There is no evidence of recurrence in follow-up CT scan 17 months after the operation until now. Conclusions: Aggressive surgical planning with PVE is effective for patient with cHCC-CC without adequate FLR even in cirrhotic liver. Complete resection may provide longer overall survival in this disease with dismal prognosis.

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        Gravity effect of silica and polystyrene particles on deposition pattern control and particle size distribution on hydrophobic surfaces

        Ting-Yu Hu,Chieh Wang,Kai-Chieh Yang,Li-Jen Chen 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.106 No.-

        Ring-like residual deposits are often observed after drying suspension droplets on surfaces. That introducesa crucial defect in practical applications, such as ink-jet printing that requires a uniform deposit. In this study, depositions after drying sessile/pendant droplets with silica/polystyrene particles wereexamined to identify the effect of gravitational sedimentation of particles on self-pinning and depositionpattern. The suspension droplet with larger polystyrene (or silica) particles would trigger the self-pinningat larger (or smaller) particle concentrations. The deposition pattern of pendant drops with silica particlesis hill-like. This is due to the large density difference between silica and water to induce high sedimentationvelocity, and the particles would precipitate and aggregate along the air–liquid interface to form ahollow shell deposit. The depositions for suspensions with bi-dispersed particles, the larger silica particleswould accumulate at the bottom of the deposit due to the higher sedimentation velocity, in contrastto the well-mixed in the deposits for bi-dispersed polystyrene particles. The sedimentation and capillaryflow velocities were calculated and discussed. These new findings reveal that the particle density (gravityeffect) can be used to adjust the sedimentation velocity to control the deposition morphology and particlesize distribution even to suppress the coffee-ring effect.

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