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      • 서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1997)

        김재홍,문득곤,김정수,김용준,임동진,박상훈,김희성,이민수,송기훈,김갑형,김형석,성소영,이인섭,김석우,황지환,조창근,김경문,부태성 대한화학요법학회 2000 대한화학요법학회지 Vol.18 No.3

        Background : In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. Objective & Methods : For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results : In 1997. 99 strains of N. gonorrhoeae were isolated, among which 45(45.5%) were PPNG. Conclusion : The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 45.5% in 1997.

      • 이동로봇의 동적 경로계획

        이우송,오세봉,안용근,문정훈,한성현 한국공작기계학회 2008 한국공작기계학회 추계학술대회논문집 Vol.2008 No.-

        This paper propose a new path planning method for mobile robots. The creation method of the course approaches with the method of the frame line graph base where the calculation time becomes disturbance. The graph composition where is not the static course plan method of existing, a course search and repeats continuously changes a graph and proposes the course the dynamic routing plan method. The method which is proposed is composed of a course creation phase and a course improvement phase, each phase includes a graph composition and a course search process.

      • 주행로봇의 경로제어

        이우송,오세봉,안용근,한성현 한국공작기계학회 2009 한국공작기계학회 춘계학술대회논문집 Vol.2009 No.-

        This paper propose a new path planning method for mobile robots. The creation method of the course approaches with the method of the frame line graph base where the calculation time becomes disturbance. The graph composition where is not the static course plan method of existing, a course search and repeats continuously changes a graph and proposes the course the dynamic routing plan method. The method which is proposed is composed of a course creation phase and a course improvement phase, each phase includes a graph composition and a course search process.

      • 서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)

        김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2

        Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.

      • SCISCIESCOPUS

        Proteogenomic Characterization of Human Early-Onset Gastric Cancer

        Mun, Dong-Gi,Bhin, Jinhyuk,Kim, Sangok,Kim, Hyunwoo,Jung, Jae Hun,Jung, Yeonjoo,Jang, Ye Eun,Park, Jong Moon,Kim, Hokeun,Jung, Yeonhwa,Lee, Hangyeore,Bae, Jingi,Back, Seunghoon,Kim, Su-Jin,Kim, Jieun Cell Press 2019 Cancer Cell Vol. No.

        <P><B>Summary</B></P> <P>We report proteogenomic analysis of diffuse gastric cancers (GCs) in young populations. Phosphoproteome data elucidated signaling pathways associated with somatic mutations based on mutation-phosphorylation correlations. Moreover, correlations between mRNA and protein abundances provided potential oncogenes and tumor suppressors associated with patient survival. Furthermore, integrated clustering of mRNA, protein, phosphorylation, and N-glycosylation data identified four subtypes of diffuse GCs. Distinguishing these subtypes was possible by proteomic data. Four subtypes were associated with proliferation, immune response, metabolism, and invasion, respectively; and associations of the subtypes with immune- and invasion-related pathways were identified mainly by phosphorylation and <I>N</I>-glycosylation data. Therefore, our proteogenomic analysis provides additional information beyond genomic analyses, which can improve understanding of cancer biology and patient stratification in diffuse GCs.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Mutation-phosphorylation correlation suggests possible signaling interplays in EOGCs </LI> <LI> mRNA-protein correlation suggests genes with high association with patient survival </LI> <LI> Integrated analysis of mRNA and protein data identified four subtypes </LI> <LI> Phosphorylation data provide cellular signaling pathways underlying the subtypes </LI> </UL> </P> <P><B>Graphical Abstract</B></P> <P>[DISPLAY OMISSION]</P>

      • Nutrient Removal Using Bauxsol<sup>TM</sup> for Treated Wastewater Reuse

        Mun, Jung Soo,Lee, Sang Ho,Lee, Jung Hun,Suh, Jeong Yul,Kim, Ree Ho Trans Tech Publications, Ltd. 2011 Materials science forum Vol.695 No.-

        <P>Urban areas consume huge amounts of water and produce much wastewater, which deteriorate the aquatic environment and exhaust the country’s freshwater resources. Water reuse from sewage and wastewater is recognized as a good option for securing water. There are several kinds of processes for improving the water quality. Nutrient removal is very important for water reuse, especially in water supply for outdoor use, to prevent water quality deterioration via eutrophication. Moreover, low cost and easy maintenance should be considered for nutrient removal. In this study, red mud and Bauxsol<SUP>TM</SUP>, a mixed mineral powder made of physicochemically modified red mud residue generated by the Bayer process for alumina refineries, was used for the removal of nitrate and heavy metals in artificial solution, and of phosphate in final effluent, from a sewage treatment plant in Dae-gu, Republic of Korea. Nitrate removal by red mud showed little efficiency while heavy metal removal showed high efficiency. The concentrations of the total phosphate in the effluent and treated water were 1.51 and 0.14 mg/L, respectively, which represent about 90.7% removal. Before and after the treatment, the pH was maintained at a neutral range of 6.5-7.2. Bauxsol<SUP>TM</SUP> also showed a high heavy metal removal capacity. Therefore, Bauxsol<SUP>TM</SUP> in powder and pellet form can be applied individually or mixed with soil to improve water quality for water reuse.</P>

      • KCI등재후보

        전신성 홍반성 루푸스 양상으로 발현된 Human Adjuvant Disease

        정자헌(Ja Hun Jung),정성수(Sung Soo Jung),문희식(Hee Sig Mun),송용호(Yong Ho Song),조영중(Young Jung Cho),오광택(Kwang Taek Oh),김태환(Tae Hwan Kim),전재범(Jae Bum Jun),이인홍(In Hong Lee),배상철(Sang Cheol Bae),유대현(Dae Hyun Yoo) 대한내과학회 1998 대한내과학회지 Vol.54 No.2

        Human adjuvant disease means the autoimmune disease or autoimmune disease like syndrome developed after plastic surgery using foreign body implantation. After first report of l by Miyoshi at 1964, a number of cases have been reported especially from Japan. Silicone has been known as biologically inert material, but a couple of side reaction and experimental data argue against such conventional idea. It is impossible to identify the exact role of implanted substance in the occurrence of autoimmune disease, but there are a few indirect evidences for adjuvant effect of silicone. The spectrum of HAD are as follows: unclassifiable connective disease like syndrome, rheumatoid arthritis, SLE, polymyositis, adult Still's disease, ITP, Hashimoto's thyroiditis, ctc. We experienced two cases of HAD manifesting as SI.E who had been injected with silicone fluid with for augmentation mammoplasty and report this with a review of the literature.

      • KCI등재후보

        Dural Arteriovenous Malformation Associated with Meningioma:Spontaneous Disappearance after Tumor Removal - Case Report -

        Mun Ho Choi,Jung Yong Ahn,Hun Kyu Choi,Byung-Hee Lee 대한신경외과학회 2003 Journal of Korean neurosurgical society Vol.33 No.2

        Dural arteriovenous malformations may be congenital, but most dural arteriovenous malformations are acquired lesions. The acquired dural arteriovenous malformations are rarely associated with brain tumors. We describe a case of dural arteriovenous malformation at the non-dominant transverse-sigmoid sinus associated with a convexity meningioma on the same side. The lesion was spontaneously disappeared after removal of the meningioma, even though the dural arteriovenous malformation was not manipulated. The authors describe a possible pathophysiology of dural arteriovenous malformations associated with tumors at the remote area and spontaneous closure after tumor resection. Key words:Dural arteriovenous malformation;Sinus thrombosis;Meningioma;Pathophysiology.

      • KCI등재

        Epitaxial Layer Design for High Performance GaAs pHEMT SPDT MMIC Switches

        Jung-Hun Oh,이진구,김삼동,Jae Kyoung Mun 한국전자통신연구원 2009 ETRI Journal Vol.31 No.3

        From a hydrodynamic device simulation for the pseudomorphic high electron mobility transistors (pHEMTs), we observe an increase of maximum extrinsic transconductance and a decrease of source-drain capacitances. This gives rise to an enhancement of the switching speed and isolation characteristics as the upper-to-lower planar-doping ratios (UTLPDR) increase. On the basis of simulation results, we fabricate single-pole-double-throw transmitter/receiver monolithic microwave integrated circuit (MMIC) switches with the pHEMTs of two different UTLPDRs (4:1 and 1:2). The MMIC switch with a 4:1 UTLPDR shows about 2.9 dB higher isolation and approximately 2.5 times faster switching speed than those with a 1:2 UTLPDR.

      • KCI등재

        구리 공급원들(Cu Sulfate, Cu-Methionine, Cu-Soy Proteinate)의 첨가가 육계의 생산성에 미치는 영향

        이문구(Mun Ku Lee),김찬호(Chan Ho Kim),신동훈(Dong Hun Shin),정병윤(Byoung Yun Jung),백인기(In Kee Paik) 韓國家禽學會 2011 韓國家禽學會誌 Vol.38 No.2

        본 연구는 구리 공급원들이 육계의 생산성, 영양소 이용률, 혈액 성상 및 근육과 간의 광물질 함량에 미치는 영향을 알아보기 위해 Cu sulfate, Cu-soy proteinate(Cu-SP), Cu-methionine chelate(Cu-Met)를 비교시험하였다. 육계(Ross<SUP>?</SUP>) 1,000수를 공시하여 4처리 5반복으로 반복당 50수씩 완전 임의 배치하여 자유 섭식케 하였으며, 35일간 전기(0~3주), 후기 (4~5주)로 나누어 실시하였다. 처리구들은 대조구, Cu sulfate (CuSO₄ · 5H₂O으로 Cu 200 ppm), Cu-Met(Cu-methione chelate 으로 Cu 200 ppm), Cu-SP(Cu-soy proteinate으로 Cu 200 ppm) 등 총 4처리였다. 증체량에서는 후기와 全사양 시험 기간 동안 구리 첨가구들이 대조구와 비교하여 유의적으로(p<0.01, 후기; p<0.05, 全사양 시험 기간) 높았으며, 사료 섭취량에서는 전기에서 Cu-Met가 대조구에 비해 유의적으로(p<0.01) 적었다. 사료 요구율(FCR)은 全시험 기간 동안구리 첨가구들이 대조구에 비해 유의적으로(p<0.01) 낮았다. 생산지수(PEF)는 구리 첨가구들이 대조구와 비교하여 유의적으로(p<0.01) 높았다. 영양소 이용률은 처리간에 유의한 차이가 없었다. 혈중 백혈구(WBC) 와 호산구(EO)의 수는 구리 첨가구들이 낮았으며, 다른 leukocytes와 erythrocytes는 처리간에 유의한 차이가 없었다. 근육 내 구리 함량은 유의한 차이가 없었으나, 가슴과 날개 근육 내 아연 함량은 구리 첨가구들에서 감소하였으나, 다리근육에서는 Cu sulfate 구에서 증가하였다. 간 내 구리 함량은 구리 첨가구들이 대조구와 비교하여 유의적으로(p<0.01) 높았다. 결론적으로 Cu sulfate, Cu-Met, Cu-SP는 육계의 증체율과 사료 요구율을 유의하게 개선하였으며, Cu 200 ppm 첨가 수준에서 Cu 공급원들 간에는 유의한 차이가 없었다. This study was conducted to investigate the effects of dietary supplementation of Cu-sulfate, Cu-methionine chelate (Cu-Met) and Cu-soy proteinate (Cu-SP) on the performance, blood parameters and mineral contents of muscle. It was conducted with a total of 1,000 one d old broilers chickens (Ross<SUP>?</SUP>) which were assigned to four dietary treatments; Control, Cu sulfate (200 ppm Cu as CuSO₄ · 5H₂O), Cu-Met (200 ppm Cu as Cu-methionine chelate), Cu-SP (200 ppm Cu as Cu-soy proteinate). There were significant differences (p<0.05) among treatments in weight gain. Weight gain of Cu treated groups were higher than the control during 3~5 wk. There were significant differences (p<0.05) among treatments in feed intake during 0~3 wk. Cu-Met was significantly (p<0.05) lower than the control but the differences among Cu treatments were not significant. There were significant differences (p<0.05) among treatments in feed conversion rate (FCR). Cu treated groups were lower than the control during the whole period. Production efficiency factor (PEF) was significantly higher (p<0.01) in Cu treated groups than the control. Nutrient availabilities of diets were not significantly different among the treatments. The count of white blood cell (WBC) and eosinophil (EO) were lower in Cu-SP treatment than in the control. Copper concentration in the liver was significantly (p<0.01) higher in Cu treated groups than the control. Zinc concentration in the breast and wing muscle was lower in Cu treated and that of leg muscle was higher in Cu-Met than the control. The result of this experiment showed that Cu supplementation at the level of 200 ppm as Cu sulfate, Cu-Met and Cu-SP improves weight gain (4~5 wk), FCR and PEF. Differences among Cu sources were not significant.

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