NANOARCHITECTURES: High‐Resolution Patterning of Various Large‐Area, Highly Ordered Structural Motifs by Directional Photofluidization Lithography: Sub‐30‐nm Line, Ellipsoid, Rectangle, and Circle Arrays (Adv. Funct. Mater. 10

Lee, Seungwoo,Kang, Hong Suk,Park, Jung‐,Ki WILEY‐VCH Verlag 2011 Advanced functional materials Vol.21 No.10

<P>A principal challenge in nanopatterning is to beat the resolution limit of established methods. On page 1770, Seungwoo Lee, Hong Suk Kang, and Jung‐Ki Park present the directional photofluidization of azopolymers, which allows the generation of large‐area, highly ordered nanoarchitectures with precisely controlled structural features. Additionally, this approach can offer unprecedented flexibility in control of the final feature size, and, simultaneously, its fluidic behavior under light irradiation signifi cantly reduces the line‐edge roughness </P>

원위 대퇴골의 고립성 골연골종에서 발생한 속발성 연골 육종 1례 보고

정필현,황장수,강석,김용민,오형호,채동주,김종필 동국대학교 경주대학 1996 東國論集 Vol.15 No.-

연골육종은 비교적 서서히 자라며 늦게 전이하는 악성 연골 종양으로 알려져 있다. 골 연골종에서 발생한 속발성 연골육종은 발생빈도는 드물며 타부위로의 전이가 적고 악성도가 낮은 경우가 많아 적합한 수술적 치료로서 좋은 예후를 보이는 것으로 보고되고 있다. 본 동국대학교 정형외과학 교실에서는 우측 대퇴골 원위부 골간단부에 생긴 고립성 골 연골종에서 이차적으로 발생한 연골육종을 치험한 바 문헌고찰과 함께 보고하는 바이다. A case of Secondary Chondrosarcoma Arising from Solitary Osteochondroma of the Distal Femur Department of Orthopaedic Surgery, College of Medicine, DongGuk University Phil Hyun Chung M.D., Jung Su Hwang M.D., Suk Kang M.D., Yang Mln Kim M.D., Hyung Ho Oh M.D., Dong Ju Chae M.D., Jong Pil Kim M.D. Chondrpsarcoma is a malignant cartilage-forming tumor that grows slowly and metastasis of this tumor occurs in late stage. Secondary chondrosarcomas arising from a solitary osteocartilaginous exostosis are rare and those have a better prognosis than other chondrosarcomas, and they rarely metastasize. We present our experience with a case of secondary chondrpsarcoma arising in solitary osteochondroma of distal metaphysis of right femur with clinical details.

Aedes aegypti 뇌추출물이 A. atropalpus의 난황단백질 합성에 미치는 효과

강석희,문정희,박영민 성균관대학교 기초과학연구소 1989 論文集 Vol.40 No.1

Aedes aegypti의 뇌추출물은 Aedes atroplpus의 지방체에 있어서의 단백질합성을 자극하였다. 자극에 의하여 증가된 단백질 합성율은 control의 130∼260%에 이르렀다. 뇌추출물의 dosage를 한 개의 지방체당 1∼4개의 머리의 상당량까지 증가하였더니 단백질 합성율은 control에 비해 130∼160%까지 증가하였다. In vitro에서의 뇌추출물의 활성은 3시간까지는 증가하였다가 점점 감소하였다. 본 연구에서 얻은 실험결과는 모기의 머리 속에는 지방체를 직접 자극하여 난황단백질 합성을 촉진시키거나, 지방체 세포에서 이미 합성, 저장되어 있는 난황단백질의 분비를 촉진시키는 요인이 존재하는 가능성을 지지한다고 사료된다. The effect of head extract on the synthesis of proteins in vitro by the fat body from Aedes atropalpus females has been examined. The head extract when added into the fat body incubation medium stimulated protein synthesis by 30∼160%. The protein synthesis stimulated by the head extract increased with time for up to 3 hours. The net increase in the total protein synthesis was equal to the net increase in the vitellogenin synthesis. The results indicated that the head extract may contain the brain factors that stimulated the yolk protein synthesis by the fat body of mosquitoes.

뚜렷한 입체 선택성을 갖는 알릴 디올의 고리 카보네이트와 아세토니드의 Wacker 산화 반응 연구

강석구,정경윤,정재욱,남궁은영,김태현 성균관대학교 기초과학연구소 1995 論文集 Vol.46 No.1

Palldium(Ⅱ) 촉매 하에서의 말단 알릴 디올의 고리 카보네이트와 아세토니드의 산화반응은 anti-Markovnikov hydation에 의해 알데히드 또는 α,β-불포화 알데히드 만이 생성되었다. 치환된 알릴 디올의 분자내 이중 결합의 반응으로는 (E)-알릴 디올의 경우에 β-케토 생성물을, 반면에 (Z)-알릴디올의 경우엔 α-케토 생성물을 얻을 수 있었다. 치환된 알릴 디올의 고리 카보네이트와 아세토니드에서는 각각 β-케토 화합물과 α,β-케토 화합물 들이 생성되었다. Palladium(Ⅱ)-Catalyzed oxidation of acetonides or cyclic carbonates of terminal allylic diols afforded aldehydes or α,β-unsaturated aldehydes as the sole products, resulting of anti-Markovnikov hydation. For the internal olefins of the substituted allylic diols, (E)-allylic diol provied β-keto-product, whereas (Z)-allylic diol affored α-keto-product. The acetonides and cyclic carbonates of the substituted allylic diols yielded β-keto-products and α,β-unsaturated ketones, respectively.

멸강나방의 성유인물질의 합성

姜錫久,정경윤 성균관대학교 기초과학연구소 1985 論文集 Vol.36 No.2

A Wittig route for the synthesis of (Z)-11-hexadecen-1-ol and (Z)-11-hexadecen-1-yl acetate, the sex attractant of the Leucania Separats is described. Esterification of 1, 10-decandicarboxylic acid, followed by partial hydrolysis of the diester gave 1, 10-dicarboxylic acid monoethylester. Hunsdiecker reeaction of the monoester gave ethyl 10-bromoundecanoate. Pyridine-N-oxide oxidation of the bramoester yielded ethyl 10-oxo-undecanoate, an aldehydoester. Olefination of the aldehydoester with pentylidenetriphenylphosphonium ylide afforded ethyl (Z)-11-decenoate. LAH reduction gave (Z)-11-hexadecen-1-ol. Acetylation of (Z)-11-hexadecenol afforded (Z)-11-hexadecen-1-yl acetate.

Culex pipiens pallens의 난황단백질 합성에 관한 연구

강석희,박영민,조정래,문정희 성균관대학교 기초과학연구소 1987 論文集 Vol.38 No.2

Anautogenous한 모기인 한국산 집모기 Culex pipiens pallens의 난황단백질 합성에 대한 hormone 들의 효과를 조사하였다. 피를 먹지않는 c. pipines 암모기의 head extract를 decapitation한 Aedes atropalpus에게 주사하였을 때 난성숙이 재유발되었으며, 난성숙의 재유발 정도는 우화 후 주사시기가 지연될수록 증가하여 우화 후 24시간에 주사하였을 때 최고에 도달하였다. 피먹은 C. pipiens를 흡혈 즉시 decapitation 또는 abdominal ligation하여도 난성숙이 저지되지 않았다. 이러한 결과는 C. pipiens의 brain hormone은 헙혈 즉시 방축되기 시작하여 난성숙의 시작을 자극하는 것으로 여겨진다. 피를 먹지않은 C. pipiens 암모기에게 β-ecdysone을 주사하거나 또는 head extract 주사 후 JHI을 처리하였을 때 fat body가 합성하는 vitellogenin의 양이 증가하였다. The effect of brain hormone, Juvenile hormone and β-ecdysone on the synthesis of vitellogenin in the anautogenous mosquito, Culex pipiens pallens, has been examined. Head extract from non-blood fed C. pipiens females, when injected into the decapitated Aedes atropalpus females, stimulated egg maturation. The ovarian development in C. pipiens was not completely blocked by decapitation or abdominal ligation performed immediately following a blood feeding. These results suggested that the release of brain hormone in this mosquito may be triggered by a feeding activity. Injection of β-ecdysone or head extract followed by topical application of JH into non-blood fed C. pipiens females stimulated vitellogenin synthesis. These results supported the previous work in Aedes aegypti that brain hormone, JH and ecdysone, in that sequence, are required for the egg maturation.

백색부후균 전처리에 의한 목재 칩의 Biopulping

강규영,김형진,양봉숙,조병묵,오정수 동국대학교 생명자원과학대학 연습림 2000 연습림논문집 Vol.- No.6

Pulping process is to mainly obtain lignocellulosic fibers for papermaking from wood resources. Three types of pulping method have been basically employed, such as chemical pulping, mechanical pulping, and their combination methods. Biopulping technique has been mainly applied in mechanical pulping by pretreatment of white-rot fungi into the ultrastructure of wood cell wall. The main purpose of biopulping is to improve the pulp qualities, paper properties, and to reduce the energy costs and environmental impact, compared to traditional pulping systems. Nowadays, biopulping is frequently tried in chemical pulping operation for environmental concept, fiber modification, improvement of physical properties of paper and economic savings. The pretreatment of white-rot fungi prior to chemical pulping could affect the swelling and softening of wood cell walls by the behaviors of modification and depolymerization of ligin compounds. This study was carried out to investigate the effectiveness of biological treatment to wood chips by white-rot fungus and its structural change of lignocellulosic fiber via kraft pulping. A rotary bioreactor was applied for pretreatment of biological action. The treatment of white-rot fungus was shown in weight loss of chips. After bio-kraft pulping, kappa number and total yield of pulps were measured, and reduced. Freeness(CSF) values were also decreased. Whereas brightness values were increased, compared to untreated control. The physical strength of handsheets was shown a slight increase in tensile, tear, burst, and folding endurance, with bio-treatments.

저가 후막 EL소자 제조 및 신뢰성 평가

강계원,김대연,이영훈,강봉석,박정현,최병호 금오공과대학교 산업기술개발연구원 2000 産業技術開發硏究 Vol.16 No.-

AC powder electroluminescence(EL) device consists of seven layers : PET substrate, transparent electrode, phosphor layer, dielectric layer, two layer metal electrodes and protective layer. Etch layer needs to control to improve electrical and optical properties. Both phosphor and dielectric layer among them is more important to increase its properties. For long-time reliability, proper choices of passivation and sealing material are essential. In this paper, influence of phosphor and dielectric layer thickness on EL performance is studied. Type of cellulos is selected as a sealing material to avoid moisture. To add two type of plasticizer to resin improves flexibility and passivation of EL devices. Through this experiments, technologies of fabrication low-cost thick film EL device can be established.

내시경적 점막절제술로 치험한 식도 과립상 세포종 1례

강혁주,김성욱,최석진,이중현,장재식,서영범,윤병구,박건욱,김성자,김용섭,강승완,이구,양창헌,이창우,김욱년,이광헌,서정일 동국대학교 의학연구소 2000 東國醫學 Vol.7 No.-

과립상 세포종은 Schwann 세포 기원으로 생각되며 인체에 비교적 드물게 발생한다. 과립상 세포종은 전신 어느 곳에서나 발견될 수 있으나 주로 혀, 구강, 피부 혹은 유방 등에서 호발하며 드물게 위장관에서 발견된다. 위장관에서는 식도에서 가장 호발하며 다음으로 위, 대장 순이다. 과립상 세포종은 대부분, 특히 위장관에서는 양성이며 소수의 악성 병변이 보고되었다. 이러한 이유와 함께 수술 전의 진단이 어렵기 때문에 과립상 세포종에 대한 근본적인 치료는 현재까지 외과적 절제술이다. 최근에 시도되는 치료방법들로는 내시경적 레이저 치료, 용종절제술, 내시경적 점막 절제술 등이 있다. 저자들은 상부 소화관 내시경검사를 시행하여 식도 과립상 세포종을 진단하고 내시경적 점막 절제술을 시행하여 합병증 없이 퇴원하여 현재 재발없이 경과 관찰중인 1례를 경험하였기에 보고하는 바이다. Granular cell tumors, which occur infrequently, are probably of Schwann cell origin. They can occur almost anywhere in the body but usually affect the tongue, oral cavity, skin, or breasts and are rarely found in the gastrointestinal tracts. The esophagus is the most frequent gastrointestinal site, followed by the stomach and the colon. Granular cell tumors are generally benign, especially in the gastrointestinal tract, some malignant lesions have been reported. For this reason, and also because preoperative diagnosis is difficult, the standard treatment for granular cell tumor has until now been surgical excision. In recent years, other therapeutic methods is endoscopic laser therapy (ELT), polypectiomy, endoscopic mucosal resection (EMR). We report a case of esophageal granular cell tumor which was diagnosed by an endoscopy and managed using an endoscopic mucosal resection without complication.

Pd 촉매 하에서 알릴 디올의 아릴화 연구 : 방향족 히드록시 케톤 및 페닐 치환된 알릴디올의 합성 Highly Selective Synthesis of Phenyl-Substituted Allylic Diols

강석구,정경윤,박찬희,남궁은영,김태현 성균관대학교 기초과학연구소 1995 論文集 Vol.46 No.2

The coupling reaction of iodobenzene with allylic diols in the presence of Pd(OAc)_2 and nBu_3P as catalysts using K_2CO_3 as base afforded the phenyl-substituted allylic diols. However, under the same reaction conditions with Et3N as base, phenyl-substituted α-hydroxy ketone was obtained.