간경변 환자에서 Oro-cecal Transit Time의 측정

원경준,이준,변유미,조민근,조주연,서정균,김영대,박찬국,김만우 朝鮮大學校 附設 醫學硏究所 2008 The Medical Journal of Chosun University Vol.33 No.2

Background: Neurotransmitter like substances in the gut have been proposed to contribute to the overall portal systemic encephalopathy (PSE). The source of the ammonia in patients with PSE is mainly the small bowel, as a result of the conversion of glutamine in the diet to glutamate and ammonia. PSE is highly responsive to changes in diet, to antibiotic therapy and to ingestion of nondigestible disaccharides such as lactulose. This study was performed to evaluate the relationship between PSE and oro-cecal transit time. In addition, performed to evaluate the effect of severity, cause, complications of liver cirrhosis on oro-cecal transit time. Methods: Between August 2006 and February 2007, 48 cirrhotic patients consecutively was enrolled in study their oro-cecal transit time after informed consent was obtained. A non-invasive hydrogen breath test was used to study oro-cecal transit time (OCTT). Result: The OCTT were delayed in cirrhotic patients with PSE compared without PSE (123.3 ± 42.7 min vs 170.0 ± 58.3 min, p<0.05). OCTT tended to prolongate further as the damage in the liver got worse, nevertheless the result was statistically meaningless (p<0.111). Neither presence of ascites or cause of PSE had any influence on gastrointestinal transit. Conclusions: Cirrhotic patients with PSE have more delayed OCTT than without PSE. Further research is needed to find out the relationship between OCTT and severity of liver cirrhosis.

라즈베리파이를 이용한 스마트미러

최서희,전준수,송민규,이재건,이순흠 순천향대학교 부설 산업기술연구소 2021 순천향 산업기술연구소논문집 Vol.27 No.2

If we are looking for something that can be found anywhere in public places, homes, and and even toilets, we will be able to choose a mirror that can easily reflect us. To satisfy the convenience needs of people, we can automatically introduce various useful information on mirrors that are often used by anyone, or add functions such as measuring human body temperature in line with the recent trend of public health due to the COVID-19 pandemic. The system presented in this paper aims to improve the convenience of users who frequently look in the mirror by displaying visual information on a translucent mirror as well as being able to reflect the image as explained above.

한국만화산업의 수출경쟁력 강화방안에 관한 연구

徐俊奭,徐敏敎 慶一大學校 1999 論文集 Vol.16 No.4

Recently, there has been rapid increase in Korean firms' export of cartoon products, reflecting the change of world and domestic economic environment. The purpose of this study are 1) to find out results of comparative study on cartoon industry between Korea and Japan 2) to evaluate possible implications for Korean firms' export of cartoon products and consider the effcient countermeasures of Korean firms.

국내은행들의 점포전략에 관한 연구

서준석,서민교 경일대학교 산업정보연구소 2000 産經硏究 Vol.6 No.2

경제위기 극복을 위한 금융산업의 구조조정이 본격적으로 진행되고 있다. 국내은행들은 금융환경변화에 적극적으로 대응해 나가는 한편, 내부적으로는 부실자산 축소 ·인력감축 등 수익 및 비용 구조를 개선하기 위해 다양한 노력을 기울이고 있다. 이 중에서도 적자점포의 통폐합 및 이전, 점포소형화, 점포신설 억제 등 코스트 절감을 위한 점포 리스트럭처링 작업이 대형 시중은행을 중심으로 강도높게 실시될 전망이다. 이러한 상황인데도 불구하고 우리나라의 은행점포전략에 대한 연구는 거의 없다는 점이다. 이와같은 상황하에서 본 연구의 목적은 첫째, 전문 ·특화 delivery system과 동해은행의 사례를 분석하고 둘째로, 국내은행의 점포전략 수립시 참조할수 있는 시사점 및 향후 연구방향에 대해 언급하였다.

폐 섬유 보강 복합재의 제조와 마찰특성

차준용,이정민,모상영,이재달,배기서,홍영기 忠南大學校 産業技術硏究所 1996 산업기술연구논문집 Vol.11 No.2

Fiber-reinforced composite materials are used in a wide variety of applications in the advanced field of industries such as electric clutch, motor, car, space and aviation etc. It is well known that the brake lining made of fiber-reinforced composites show excellent friction and wear properties compared to the conventional asbestos brakes and also are known to have high absorption energy and excellent high temperature properties in braking. In order to endow high friction and wear stability to the commercial brake lining, the waste fiber such as cotton, PAN, PET, nylon,kevlar, glass and it's binary mixture fibers were used the fiber reinforcements. The fiber/phenolic resin system has been carried out by preform molding method. The friction tester was especially designed and prepared for evaluation of frictional properties such as friction coefficient and stability. The physical properties of fiber reinforced composites were investigated in terms of the 3-point bending strength, the properties of friction, and morphology. The results obtained from the work are as follows ; 1. The friction properties of the cotton fiber reinforced composites were similar to those of the commercial brake linings, but in the cases of reinforcement of kevlar, glass. we can improve those properties, 2. The proper amount of organic and inorganic fiber mixtures can improve the properties of friction and the mechanical properties, 3. It is more desirable to manufacture hybrid fiber reinforced composites because single cotton or synthetic fiber reinforced composites aren't improved frictional properties, and 4. On evaluating frictional properties of waste fiber reinforced composites, frictional properties of waste fiber reinforced composites are superior to commercial disc lining. Therefore we can confirm practical possibility of waste fiber reinforced disc lining.

Oct4 단백질의 DNA - 결합 영역에 융합된 HIV - 1 integrase

이민전,서진욱,김미라,신차균 中央大學校 遺傳工學硏究所 2002 遺傳工學硏究論集 Vol.15 No.1

Human immunodeficience virus type-1 (HIV-1) integrase (IN) mediates integration of viral DNA into the host cell genome which is an essential step during the life cycle of retroviruses. HIV-1 IN shows four enzymatic activities in vitro: non-specific DNA- binding, endonucleolytic (3'-processing), integration (strand transfer), and disintegration activities. Oct4 as a transcription factor recognizes and binds the specific sequences containing 5' -ATGCAAAT-3'. In order to study the specific binding and enzymatic activities of the integrase protein, we constructed the four different fusion proteins (OctIN1, OctIN2, INKOct1, INKOct1) using different combination of HIV-1 IN and Oct4 protein. The fusion proteins were overexpressed in Escherichia coli and purified by Ni-NTA and SP-sepharose columns. Analysis of the enzymatic activities showed that all the four fusion proteins has detectable endonucleolytic and integration activities, suggesting that the fusion proteins can be used to study derected integration and sequence specific DNA-binding of the integrase fusion protein.

보리순의 영양성분 조성

서혜지,최용민,김상천,이준수,이기택,정명근,천지연,황진봉,남진식,서우덕,황영,김행란,김세나 忠北大學校 農業科學硏究所 2015 農業科學硏究 Vol.31 No.2

경호상황에서 태권도기법의 적용방법에 관한 연구

박준석,서민학 龍仁大學校 武道硏究所 2004 武道硏究所誌 Vol.15 No.1

This study shows how to apply Taekwondo as a Protectional Martial Art Generally every learning territory is divided into cultural and social science and natural science. In the same manner, the study of guarding should be broken into parts so as to make the most of guarding characteristics. I think that Protection Martial Art will develop in learning because it can motivate Taekwondo participants to study it. I will attempt to show a developing study of Taekwondo as a Protection Martial Art. A Guard is a final method in which deals with each kind of threats. The timing, the place and the way of attempt to inflict an injury is decided by the attactor. The situation of attact is also has many variables. If there isn't a Guard Martial Art or the bodyguard is irresolute, it is difficult to control the attactor. Therefore, the ultimate aim of Protection Martial Art is not only to protect a guarded person from danger through complete training, but also facing an attact and controling it effectively. In order to insure the guarded person's life from the harmer, the bodyguard has to perform his duty from a high degree of training. So training in Protection Martial Art is a necessary condition. When the bodyguard faces an attact and deals with it, he has to grasp and meet the situation - the environment, the direction and the way of attact. Also recognize the a kind of weapon, the attactor's skill and ability and so on. A high degree of guard technics and Guard Martial Art is essential to face and deal with an attact. Owing to establish Protection Martial Art systematically, this shows how to apply Taekwondo training technics to Protection Martial Art and how to deal with a situation of guarding in the event of attact by using basic technics from Taekwondo. First, by studying the system of Protection Martial Art based on Taekwondo, I developed Taekwondo training technics as a Protection Martial Art. Second, "Stance posture" should be neat and sharp. I intend to show the posture-"Parallel Stance"- which is easy to offend and defend in every direction. Moreover it is more developed than it was. Third, I show a desirable "Stance posture" as a guard's position, so that the guard can deal with the dangerous situation promptly and properly. Fourth, I try to show the way how to control an accidental occurance by using a based action and an applied action from Taekwondo as a guard technic. Therefore, I think that the system of Protection Martial Art based on Taekwondo should be studied and Taekwondo should be established as a Protectional martial art. Training Taekwondo as a Protectional martial art enables one to handle any unexpected situation by mastering its theory and basic skills. I consider that we should practice Taekwondo technics through a real model to deal with various dangerous situations.

좌측흉수로 발현된 Boerhaave 증후군 1예

이준,변유미,조민근,조주연,원경준,김영대,박찬국,김만우,유재근,서홍주,이석기 朝鮮大學校 附設 醫學硏究所 2008 The Medical Journal of Chosun University Vol.33 No.2

구토 후 발생한 토혈을 주소로 내원한 환자에서 좌측 늑막 삼출 동반 시 식도 파열의 가능성을 고려하여 흉수 천자 및 지속적인 흉부 단순 촬영의 추적관찰이 필요하며 식도 파열이 배제된 후 환자의 생체 징후 및 토혈 양을 파악하여 내시경 검사 시기를 신중히 결정하는 것이 좋을 것으로 생각된다. 본 증례는 토혈을 주소로 내원하여 Mallory-Weiss 증후군 의심 하에 내시경을 통한 치료 시행 후 추적 관찰에 의해 진단된 Boerhaave 증후군을 경험하였기에 보고하는 바이다. Boerhaave's syndrome is a spontaneous perforation of the esophagus most commonly resulting from a sudden increase in intraesophageal pressure combined with negative intrathoracic pressure caused by straining or vomiting. Surgery should generally be performed within 24 hours because mortality approached 30 to 50 percent in which surgery was delayed. Therefore, early diagnosis and prompt surgical repair are critical for survival. We have experienced a case of Boerhaave's syndrome in a patient presenting with hematemesis with left pleural effusion without any signs or symptoms of pneumomediastinum or pneumothorax.

정신분열병 환자에서의 한국어판 사회적응 척도의 개발 : 신뢰도 및 타당도 연구

김철권,서지민,김상수,조진석,하준선,김정옥,변원탄 大韓神經精神醫學會 1999 신경정신의학 Vol.38 No.6

연구목적: 정신분열병 환자의 사회적응 정도를 측정하는데 사용되는 사회적응 척도의 한국어판을 개발하기 위함이다. 방 법: 사회적응 척도를 번역한 후 정신분열병 환자 67명과 정상인 78명을 대상으로 신뢰도와 타당도를 검증하였다. 결 과: 자료분석 결과 검사-재검사 신뢰도는 0.85, 검사자간 신뢰도는 0.89, 내적 일치도는 0.87로 높은 수치였다. 변별 타당도를 검증하기 위하여 정신분열병 환자군과 정상 대조군을 비교한 결과 정신분열병 환자군에서 사회적응 정도가 유의하게 낮았다. 구성 타당도를 알아보기 위하여 10개 영역간의 상관관계를 측정한 결과 성적적응 영역을 제외한 모든 영역들에서 유의한 상관관계를 보였다. 본 척도의 전반적 평가 영역 결과와 GAF 결과간의 상관성을 통해 간접적으로 검증한 공존 타당도 역시 유의하였다. 결 론: 한국판 사회적응 척도는 우수한 신뢰도와 타당도가 입증되었고 나아가 정신분열병 환자의 사회적응 정도를 평가하는데 유용하게 사용되어질 수 있을 것이다. Objectives: The purpose of this study was to develop the Korean version of the Social Adjustment Scale Ⅱ-Revised Version(KSAS Ⅱ-RV) in the schizophrenics. Methods: KSAS Ⅱ-RV was administered to 67 schizophrenic patients and 78 matched normal controls for examining the reliability and validity. Results: Data analysis showed statistically significant reliabilities and validities of KSAS Ⅱ-RV. The test-retest reliability, inter-rater reliability, and internal consistency for total scores of KSAS Ⅱ-RV were 0.85, 0.89. and 0.87, respectively. Evidence for discriminant validity of KSAS Ⅱ-RV comes from the results that the mean scores of schizophrenic patients were significantly high than those of normal controls. Construct validity was assessed by calculating the 10 inter-subareas correlations of the KSAS Ⅱ-RV, and all except the sexual adjustment area were statistically significant. Significant correlations between the global area scores of KSAS Ⅱ-RV and those of Global Assessment of Functioning Scale lend support for the concurrent validity of this instrument indirectly. Conclusions: KSAS Ⅱ-RV was found to be a valid and reliable instrument which can be used to evaluate the degree of social adjustment in the schizophrenic patients.