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      • KCI등재

        GIS기반 동남 광역권 산업체 정보시스템 구축 및 활용

        남광우 ( Kwang Woo Nam ),권일화 ( Il Hwa Kwon ),박준호 ( Jun Ho Park ) 한국지리정보학회 2014 한국지리정보학회지 Vol.17 No.1

        광역 교통망 및 통신기술의 발전에 따라 광역경제권의 활성화를 위한 협력체계의 중요성이 날로 증대되고 있다. 이에 본 연구는 동남권 광역경제권을 대상으로 GIS 기반의 산업체 정보 공유를 목적으로 동남권 산업체 정보시스템을 구축하였다. 동남권의 경우 제조업 중심의 산업 집적지로서 행정경계를 넘어 산업체간의 근접성과 연결성을 고려한 효율적인 산업 클러스터 및 협력체계 운영이 요구된다. 정보시스템의 DB 구축을 위해 부산, 울산, 경남에서 구축되어진 산업체 DB를 활용하여 정보시스템을 구축한 바, 각 지자체간 데이터의 불일치와 GIS기반의 위치정보 미흡으로 인한 여러 가지 문제점을 발견하였다. 이의 해결을 위해서는 수집 및 배포, 활용과정을 고려한 표준화가 시급한 것으로 분석되었다. 본 연구는 산업체 정보의 공간정보화를 위해 지적도와 수치지도를 활용하여 웹상에서 관리자-사용자 쌍방향간의 정보생성 및 단계별 접근이 가능한 2-way 방식의 산업체 정보시스템을 구축하였다. 본 연구의 결과는 동남권 산업육성을 위한 협력체계 및 공동대응을 위한 산업체 정보 공유체계의 기초적 틀을 제공하였다는 데 그 의의가 있다고 하겠다. Following the technology developments of traffic network and communication for the wide area, the importance of the cooperation system to vitalize the wide area economy is increasing. Therefore, in this study, DongNam Kwon industry information system is established for the industrial information sharing based on GIS in the DongNam Kwon wide area economy. The DongNam Kwon is an industrial integration area centered with the manufacturing so that the operation of effective industrial cluster and cooperation systems are required across the administrational boundaries. To establish the database of the information, the information system was established utilizing already established industrial databases in Busan, Ulsan and Gyeongnam. But, various issues caused by the discordances among the data of each local government and the insufficiency of GIS based location information have been found. According to the analysis, the standardization considering the courses of collection, distributions and utilization are required immediately to solve the issues. This study establishes an 2-way industrial information system enabling the information creation and the phased approach between the administrator and the user in the bi-directions on the web by utilizing cadastral and numerical maps. The result of this study would have a meaning in providing a fundamental frame for cooperative responses and cooperation system for DongNam Kwon``s industrial promotion using industrial information sharing.

      • KCI등재

        A rare case of miliary tuberculosis accompanying perihepatitis

        Ou Jun Kwon1,이석우,장문순,김상철,이지한,김훈 대한응급의학회 2019 Clinical and Experimental Emergency Medicine Vol.6 No.3

        Perihepatic capsulitis is associated with various diseases, such as Fitz-Hugh-Curtis syndrome, systemic lupus erythematosus, perforated cholecystitis, perforated hepatic abscess, and tuberculous peritonitis. Miliary tuberculosis is present in about 2% of all reported cases of tuberculosis and is characterized by the widespread millet-like hematogenous dissemination of Mycobacterium tuberculosis. We describe a 24-year-old virgin patient presenting with right upper quadrant and costovertebral angle pain. Diffuse perihepatic capsular enhancement was observed in abdominal computed tomography scans. Chest radiography showed miliary tuberculosis, and a polymerase chain reaction hybridization assay of sputum revealed the presence of M. tuberculosis. Symptoms improved after administering anti-tuberculosis medications. This report describes a rare case of miliary tuberculosis accompanying perihepatitis.

      • 단백뇨를 보이는 사구체 질환 및 당뇨병성 신병증에서의 Lp(a)

        권태환,김준홍,조성,김석재,김용림,조동규,백미영 경북대학교 병원 1998 경북대학교병원의학연구소논문집 Vol.2 No.1

        Background: Recently there has been evidences that serum Lp(a), an independent risk factor to atherosclerotic cardiovascular diseases, were increased in proteinuric disorders such as nephrotic syndrome and diabetic nephropathy. Methods: We intended to search of altered concentrations of Lp(a) in proteinuric disorder measuring serum Lp(a) concentrations with ELISA in 44 glomerulonephritic patients(25 nephrotic syndrome(NS), 19 non-nephrotic range proteinuric glomerulonephritis(GN), 25 diabetic nephropathy patients(DN), and 31 healthy controls(HC). Also, we compared Lp(a) concentration between glomerulonephritis patients and diabetic nephropathy patients with proteinuria of similar degree. Results: 1) There were significantly increased levels of total choesterol, triglyceride, and LDL-cholesterol in Ns compared to GN, DN, HC. 2) There were significantly increased concentrations of serum Lp(a) in NS compared to HC, but no signiicant difference in serum Lp(a) among NS, GN, and DN. 3) There was no significant difference in serum Lp(a) concentrations between NS & DN with 24 hour urine protein greater than 3.0g. 4) There was no significant difference in serum Lp(a) concentration between GN with 24 hour urine protein greater than 0.5g and less than 1.5g and DN with proteinuria of simial degree. 5) In glomerulonephritis patients, there was negative correlation between serum Lp(a) concentration and serum albumin level but correlation with 24 hour urinary protein, total cholesterol, Ldl-cholesterol, and HDL-cholesterol was not shown. In diabetic nephropathy, there was no significant correlation among serum Lp(a) concentration and all parameters including serum albumin, 24 hour urinary protein, and other lipid profiles. Conclusion: The present study confirmed that patients with nephrotic syndrome of diverse etiologies have makedly increased plasma level of Lp(a), in conjunction with other lipid abnormalities. However, this study shows no difference in Lp(a) concentrations between diabetic nephropathy and glomerulonephritis with similar degree of proteinuria.

      • 다시점 영상 방송을 위한 플레이어 모델의 설계 및 구현

        권준섭,김만배,최창열 강원대학교 정보통신연구소 2007 정보통신논문지 Vol.11 No.-

        With the rapid development of computing technology, multi-view video is attracting extensive interest recently due to its greatly enhanced viewing experience. In this paper, we propose an integrated display solution model and present the prototype system for multi-view video. The player can display and verify the multi-view video. For verifying the accuracy of synthesizing graphics, it can display in both 2D and 3D mode, and save frames into various format. And, in experiments we can select not only degree of stereoscopic effect but also number of intermediate views between real cameras. With this system, users are able to select their desired viewing directions and enjoy many exciting visual experiences, such as view switching, freeze and rotate and view sweeping, with great freedom.

      • 니코틴 대사와 CYP2A6 유전자 빈도에 관한 민족적 다형성

        권준택 순천향의학연구소 2000 Journal of Soonchunhyang Medical Science Vol.6 No.2

        사람의 CYP2A6 유전자는 CYP2A6*1A, CYP2A6*1B, CYP2A6*2, CYP2A6*3, CYP2A6*4 및 CYP2A6*5 대립 유전자가 밝혀져 있으며, nicotine-C 산화반응을 촉매하고 있다. 앞선 보고에 의하면, 일본인에서 nicotine 대사의 개인간 차이는 CYP2A6 유전자 다형성 (genetic polymorphism)과 관련이 있음이 증명된 바 있다. 저자는 Nicotine대사와 CYP2A6 대립 유전자들의 빈도에서 인종간의 차이를 증명하기 위해 209예의 한국인에서 nicotine대사와 CYP2A6의 유전자형을 연구하였다. Nicotine 껌을 투여 후 2시간에 혈장 cotinine/nicotine 비를 계산하여 nicotine대사의 지표로 사용하였으며, CYP2A6의 유전자형은 PCR-RFLP방법으로 결정하였다. 실험 결과 CYP2A6*1A, CYP2A6*1B, CYP2A6*4 및 CYP2A6*5 대립 유전자의 빈도는 한국인 (각각 45.7%, 42.8%, 11.0% 및 0.5%)과 일본인간에는 인종간의 차이를 보였다. 그러나 CYP2A6*2와 CYP2A6*3 대립 유전자형에는 어떠한 차이도 관찰할 수 없었다. 4명의 CYP2A6*4 homozygotes에서는 cotinine형성이 완전히 결여되었으며 그 결과는 일본인에서 관찰된 자료와 일치하였다. CYP2A6*4 heterozygotes에서는 이것이 없는 사람들에 비해 낮은 대사율을 보이는 경향이 있었으며, CYP2A6*1B 대립유전자를 지닌 사람들은 cotinine 형성 능력이 훨씬 높은 경향을 나타내었다. 니코틴 대사의 개인별 차이는 CYP2A6의 유전자 다형과 밀접한 관련이 있음을 확인하였다. 한국인에서 대사율의 probit plot 결과는 0.6의 antimode치를 보여 일본인에서 얻은 결과와 동일하였다. CYP2A6*1B/CYP2A6*4를 가진 한 명의 한국인에서 새로운 CYP2A6 돌연변이가 있는 것으로 보였다. 한국인의 probit plot 결과는 일본인보다 높은 비를 보였으며, 각 유전자형 군에서 한국인 군은 일본인 군에 비하여 유의하게 높은 대사율을 보였다. Cotinine 형성에서 인종간의 차이는 유전학적 소인 외에도 환경인자 및 식이 등의 인자들이 관여할 것으로 보인다.

      • KCI등재

        해마 theta리듬과 pyramidal neuron의 세포내 특성과의 상관관계

        권오흥,조진화,남순현,김현정,최병주,김영진,이만기 大韓小兒齒科學會 1998 大韓小兒齒科學會誌 Vol.25 No.4

        Eledctrophysiological phenomena of pyramidal cells in the CAI area of the dorsal hippocampus were recorded from and filled with neurobiotin in anesthetized rats. The electropharmacological properties of membrane as well as the cellular-synaptic generation of rhythmic slow activity (theta)were examined. The intracellular response characteristics of these pyramidal cells were distinctly different from responses of inteneurons. Pyramidal cells had a high resting membrane potential, a low input resistance, and a large amplitude action potential. A afterhyperpolarization was followed a single action potential. Most of pyramidal cells did not display a spontaneous firing. Pyramidal cells displayed weak inward rectification and anodal break excitation. The slope of the frequency-current relation was 53.4 Hz/nA for the first interspike interval and 15.9 Hz/nA for the last intervals, suggesting the presence of spike frequency adaptation. Neurobiotin-filled neurons showed pyramidal morphology. Cells were generally bipolar dendritc processes ramifying in stratum lacunosum-moleculare, radiatum, and oriens. Commissural stimulation discharged pyramidal cells, followed by excitatory and inhibitory postsynaptic potentials (EPSPs and IPSPs). The frequency of theat-related membrane potential oscillation was voltage-independent in pyramidal neurons. At strong depolarization levels (less than 30 mV) pyramidal cells emitted sodium spike oscillation, phase-locked to theta. The observations provide direct evidence that theta-related rhythmic hyperpolarization of principal cells is brought by the rhythmically discharging interneurons. Furthermore, the findings in which interneurons were also paced by rhythmic inhibitory postsynaptic potentials during theta suggest that they were periodically hyperpolarized by their GABAergic septal afferents.

      • KCI등재
      • 이동전화 단말기 판매보조금 실태조사 연구

        권준식 世明大學校 1998 世明論叢 Vol.7 No.-

        In this paper, to propose the healthy policy for the good mobild communication service. I researched an actual state of the mobile telephone sale subsidy and subscribers of cellular and PCS companies. I investigated the present conditions of mobile communicaion service and the point at issue, and propose the desirable strategies such as the improvement of call quality through a network construction and added service expansion and the healthy strategy such as the removal of obligaiton subscription term and the reduction of call fee.

      • Aceclofenac 경구제제의 생물학적 동등성 연구

        권준택,김형기,손동렬,염윤기 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.1

        The bioequivalence of generic aceclofenac(Anacle^(®), Korea Pharma Co.) tablet to the aceclofenac tablet(Arital^(®), DaeWoong Pharmaceutical Co.) as a reference drug. Single dose of 100 mg aceclofenac was administered to 20 healthy male volunteers in a balanced, randomized crossover design with a washout between the two study periods. Blood samples were collected up to 12 hours and plasma concentration of aceclofenac was measured by well validated reverse phase high-performance liquid chromatography. Pharmacokinetic parameters were analyzed by non-compartmental analysis and ANOVA test was used for the statistical analysis of parameters. No statistically significant formulation, period, or sequence effect was encountered. Ninety percent confidence intervals of log transformed C_(max) and AUC_(t) were comprised in the stipulated 0.80-1.25 range. These results suggest that test formulation of aceclofenac is bioequivalent with the reference, both formulations in 100 mg tablet.

      • 리눅스 기반 모바일 노드의 끊김없는 이동성 지원 시스템

        권준섭,최황규,최창열 강원대학교 정보통신연구소 2006 정보통신논문지 Vol.10 No.-

        To provide seamless networking for mobile devices, the automatic selection of the most suitable AP(Access Point) as well as the maintenance of seamless session during hand-over have been an important issue in wireless mobile network field. Despite such importance, previous activities do not provide solutions for automatic hand-over, so that seamless session is usually not guaranteed. Supporting seamless mobility makes mobile networking service easy to implement. In this paper, we propose a Linux-based seamless networking solution that can overcome aforementioned disadvantages. The efficient selection of AP can be made in the Linux environment according to the value of link quality. Active hand-over is supported and automatic AP management is designed for the mobility of wireless mobile devices. Furthermore, automatic access to wireless networks is one of the merits.

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