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      • Electrically assisted pressure joining of titanium alloys

        Li, Yong-Fang,Das, Hrishikesh,Hong, Sung-Tae,Park, Ju-Won,Han, Heung Nam Elsevier 2018 Journal of manufacturing processes Vol.35 No.-

        <P><B>Abstract</B></P> <P>Electrically assisted pressure joining (EAPJ) of a Grade 1 titanium (Ti) alloy is experimentally investigated. In EAPJ, an electric current is directly applied to the specimen during plastic compression. Microstructural analysis shows that solid-state joints are successfully fabricated in the selected Ti alloy without melting. Shear tensile tests shows that the strength and fracture modes of the joint are strongly affected by a combination of the amount of plastic deformation (corresponding to a thickness reduction) and the electric current intensity. An optimal thickness reduction, corresponding to the maximum fracture load, exists for each value of current intensity, and decreases as current intensity increases. A higher fracture load can be obtained by adjusting the combination of the current intensity and the thickness reduction parameters.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Ti alloy are solid-state joined by electrically assisted pressure joining (EAPJ). </LI> <LI> The strength and fracture mode of the joint are affected by the EAPJ parameters. </LI> <LI> An optimal thickness reduction exists for each value of current intensity. </LI> <LI> The optimal thickness reduction decreases as the current intensity increases. </LI> </UL> </P>

      • Combined Screening of Cervical Cancer, Breast Cancer and Reproductive Tract Infections in Rural China

        Li, Zhi-Fang,Wang, Shao-Ming,Shi, Ju-Fang,Zhao, Fang-Hui,Ma, Jun-Fei,Qiao, You-Lin,Feng, Xiang-Xian Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.7

        Objectives: To investigate the current prevalence and knowledge of cervical cancer, breast cancer and reproductive tract infections (RTIs) in rural Chinese women, and to explore the acceptance and feasibility of implementing a combined screening program in rural China. Methods: A population-based, cross-sectional study was conducted among women aged 30 to 59 years old in Xiangyuan County, Shanxi Province from 2009 to 2010. Socio-demographic characteristics, knowledge of cervical cancer, breast cancer and RTIs, and the attitude toward single or combined screening were collected by an interview questionnaire. Each participant received a clinical examination of the cervix, breast and reproductive tract. Examinations included visual inspection, mammography, laboratory tests and pathological diagnosis. Results: A total of 1,530 women were enrolled in this study. The prevalence of cervical precancerous lesions, suspicious breast cancer, suspicious benign breast disease and RTIs was 1.4%, 0.2%, 14.0% and 54.3%, respectively. Cervicitis, trichomonas vaginitis, and bacterial vaginitis were the three most common RTIs among our participants. Television, radio broadcast, and public education during screening were the major source of healthcare knowledge in rural China. Moreover 99.7% of women expressed great interest in participating in a combined screening project. The affordable limit for combined screening project was only 50 RMB for more than half of the rural women. Conclusion: A combined screening program would be more effective and popular than single disease screening projects, while appropriate accompanied education and a co-pay model for its successful implementation need to be explored, especially in low-resource settings.

      • KCI등재

        Microwave-assisted Approach for the Rapid Enzymatic Digestion of Rapeseed Meal

        Ju-Fang Li,Fang Wei,Lu-Lu Guo,Gang-You Yuan,Feng-Hong Huang,Mu-Lan Jiang,Yuan-Di Zhao,Xu-Yan Dong,Guang-Ming Li,Hong Chen 한국식품과학회 2010 Food Science and Biotechnology Vol.19 No.2

        This study demonstrates the use of a new microwave-assisted approach for accelerating the enzymatic digestion of rapeseed meal. The effects of different microwave parameters, such as the time, temperature, and power level, on the degree of hydrolysis (DH) were investigated by using response surface methodology (RSM). The maximum predicted DH value (10.2%) was in good agreement with the value obtained experimentally using an alkaline protease, which was 12.57% under optimal conditions. In only 7 min, the microwave-assisted method achieved a DH value similar to that obtained by the conventional enzymatic digestion method (4 hr). Therefore,this new technique for rapid enzymatic digestion will improve the application of rapeseed meal in the preparation of protein hydrolysates for use in food and feed.

      • A Multi-center Survey of HPV Knowledge and Attitudes Toward HPV Vaccination among Women, Government Officials, and Medical Personnel in China

        Zhao, Fang-Hui,Tiggelaar, Sarah M.,Hu, Shang-Ying,Zhao, Na,Hong, Ying,Niyazi, Mayinuer,Gao, Xiao-Hong,Ju, Li-Rong,Zhang, Li-Qin,Feng, Xiang-Xian,Duan, Xian-Zhi,Song, Xiu-Ling,Wang, Jing,Yang, Yun,Li, Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.5

        Objectives: To assess knowledge of HPV and attitudes towards HPV vaccination among the general female population, government officials, and healthcare providers in China to assist the development of an effective national HPV vaccination program. Methods: A cross-sectional epidemiologic survey was conducted across 21 urban and rural sites in China using a short questionnaire. 763 government officials, 760 healthcare providers, and 11,681 women aged 15-59 years were included in the final analysis. Data were analyzed using standard descriptive statistics and logistic regression. Results: Knowledge of HPV among the general female population was low; only 24% had heard of HPV. Less than 20% of healthcare providers recognized sexually na$\ddot{i}$ve women as the most appropriate population for HPV vaccination. There was high acceptance of the HPV vaccine for all categories of respondents. Only 6% of women were willing to pay more than US $300 for the vaccine. Conclusions: Aggressive education is necessary to increase knowledge of HPV and its vaccine. Further proof of vaccine safety and efficacy and government subsidies combined with increased awareness could facilitate development and implementation of HPV vaccination in China.

      • KCI등재

        Differential Responses to Short-term Salinity Stress of Heat-tolerant Cherry Tomato Cultivars Grown at High Temperatures

        Fang-Yi Liu,Kuo-Tan Li,Wen-Ju Yang 한국원예학회 2014 Horticulture, Environment, and Biotechnology Vol.55 No.2

        Although many new tomato cultivars with various degrees of heat-tolerance have been released, year-roundtomato production in subtropical lowlands is still challenged by summer heat and an increasing risk from salinity stress. Little information about the simultaneous effects of heat and salinity on growth and fruiting in tomatoes is available. It was hypothesized that cultivars which perform better in high temperatures are also more tolerant to salinity stress. Two highly heat-tolerant cultivars, ‘Tainan ASVEG No. 19’ (TA19) and ‘Taiwan Seed ASVEG No. 22’ (TSA22), andone moderately heat-tolerant cultivar, ‘Hualien ASVEG No. 21’ (HA21), were grown under high temperature conditionsand were irrigated with a 0, 50, 150, or 200 mM NaCl solution for 20 days. Vegetative growth, fruiting behavior,and fruit quality were monitored. Number of leaves, leaf area, shoot fresh and dry weights, and root fresh weightwere generally decreased with increasing level of salinity stress, but root dry weight was not affected, resulting in anincrease in root to shoot ratio in all three cultivars. Yield was also decreased by salinity treatments in all threecultivars due to reduced number of flowers, fruit set, and fruit size. The highly heat-tolerant ‘TA19’ had the lowestvegetative growth and the highest yield under the high temperature condition, but the yield was strongly suppressedby the short-term mild salinity treatment. On the other hand, vegetative growth was little affected and the degree ofyield reduction was less intense with the short-term mild salinity treatment in the moderately heat-tolerant ‘HA21’. The result indicated that effects of heat stress and salinity stress are not additive and differential responses to salinityunder high temperatures exist among cultivars with various degrees of heat-tolerance.

      • Correlation Between Mammograghic Findings and Clinical/Pathologic Features in Women with Small Invasive Breast Carcinomas

        Li, Jun-Nan,Xu, Jing,Wang, Ju,Qing, Chun,Zhao, Yu-Mei,Liu, Pei-Fang Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.24

        Background: To study the relationship between mammographic findings and clinical/pathologic features in women with 1-15mm sized invasive breast cancer. Materials and Methods: We investigated a consecutive series of 134 cases diagnosed in Tianjin Medical University Cancer Institute and Hospital in 2007. Mammographic findings were classified into five groups as follows :1) stellate mass without calcification; 2) non-stellate mass without calcification; 3) intermediate suspicious calcification with or without associated mass; 4) higher probability malignant calcification with or without associated mass; 5) focal asymmetry/distortion without associated calcification. Associations between mammographic and clinical/pathological features (menopause status/family history/histologic grade/lymph node status and ER/PR/HER2 status) was analyzed through logistic regression and chi square tests. Results: Compared to the stellate mass without calcification group, higher probability malignant calcification patients were associated significantly with a positive lymph node status, always presenting in patients who were non-menopausal and with a family history of carcinoma. Conclusions: Higher probability malignant calcifications with or without associated tumor masses are associated with clinical/pathologic features of poor prognosis.

      • SCISCIESCOPUS

        INTERACTIONS OF THE INFRARED BUBBLE N4 WITH ITS SURROUNDINGS

        Liu, Hong-Li,Li, Jin-Zeng,Wu, Yuefang,Yuan, Jing-Hua,Liu, Tie,Dubner, G.,Paron, S.,Ortega, M. E.,Molinari, Sergio,Huang, Maohai,Zavagno, Annie,Samal, Manash R.,Huang, Ya-Fang,Zhang, Si-Ju American Astronomical Society 2016 The Astrophysical journal Vol.818 No.1

        <P>The physical mechanisms that induce the transformation of a certain mass of gas in new stars are far from being well understood. Infrared bubbles associated with H II regions have been considered to be good samples for investigating triggered star formation. In this paper we report on the investigation of the dust properties of the infrared bubble N4 around the H II. region G11.898+0.747, analyzing its interaction with its surroundings and star formation histories therein, with the aim of determining the possibility of star formation triggered by the expansion of the bubble. Using Herschel PACS and SPIRE images with a wide wavelength coverage, we reveal the dust properties over the entire bubble. Meanwhile, we are able to identify six dust clumps surrounding the bubble, with a mean size of 0.50 pc, temperature of about 22 K, mean column density of 1.7 x 10(22) cm(-2), mean volume density of about 4.4 x 10(4) cm(-3), and a mean mass of 320M(circle dot). In addition, from PAH emission seen at 8 mu m, free-free emission detected at 20 cm, and a probability density function in special regions, we could identify clear signatures of the influence of the H II region on the surroundings. There are hints of star formation, though further investigation is required to demonstrate that N4 is the triggering source.</P>

      • Exogenous p53 Upregulated Modulator of Apoptosis (PUMA) Decreases Growth of Lung Cancer A549 Cells

        Liu, Chun-Ju,Zhang, Xia-Li,Luo, Da-Ya,Zhu, Wei-Feng,Wan, Hui-Fang,Yang, Jun-Ping,Yang, Xiao-Jun,Wan, Fu-Sheng Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.2

        Purpose: To investigate the influence of exogenous p53 upregulated modulator of apoptosis (PUMA) expression on cell proliferation and apoptosis in human non-small cell lung cancer A549 cells and transplanted tumor cell growth in nude mice. Materials and Methods: A549 cells were divided into the following groups: control, non-carrier (NC), PUMA (transfected with pCEP4-(HA) 2-PUMA plasmid), DDP ($10{\mu}g/mL$ cisplatin treatment) and PUMA+DDP (transfected with pCEP4-(HA)2-PUMA plasmid and $10{\mu}g/mL$ cisplatin treatment). The MTT method was used to detect the cell survival rate. Cell apoptosis rates were measured by flow cytometry, and PUMA, Bax and Bcl-2 protein expression levels were measured by Western blotting. Results: Compared to the control group, the PUMA, DDP and PUMA+DDP groups all had significantly decreased A549 cell proliferation (p<0.01), with the largest reduction in the PUMA+DDP group. Conversely, the apoptosis rates of the three groups were significantly increased (P<0.01), and the PUMA and DDP treatments were synergistic. Moreover, Bax protein levels significantly increased (p<0.01), while Bcl-2 protein levels significantly decreased (p<0.01). Finally, both the volume and the weights of transplanted tumors were significantly reduced (p<0.01), and the inhibition ratio of the PUMA+DDP group was significantly higher than in the single DDP or PUMA groups. Conclusions: Exogenous PUMA effectively inhibited lung cancer A549 cell proliferation and transplanted tumor growth by increasing Bax protein levels and reducing Bcl-2 protein levels.

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