Dopamine Transporter SPECT of a Liver Cirrhotic with Atypical Parkinsonism

KIM, Jongchul,KIM, Jong-Min,KIM, Yu Kyeong,SHIN, Jung Woo,CHOI, Seong Hoon,KIM, Sang Eun,KIM, Yangho National Institute of Industrial Health 2007 Industrial health Vol.45 No.3

<P>High level of exposure to manganese (Mn) can cause a clinically and pathophysiologically distinct syndrome from idiopathic Parkinson's disease (PD). We describe the clinical features and results of [<SUP>123</SUP>I]-fluoropropyl (FP)-CIT SPECT of a liver cirrhotic with atypical parkinsonism. The patient developed atypical parkinsonian features associated with elevated blood Mn from hepatic dysfunction. [<SUP>123</SUP>I]-FP-CIT brain SPECT images of dopamine transporter (DAT) demonstrated overall normal range of DAT uptake in the striatum although there were scattered small hypodense regions. The globus pallidum had increased signal on T1-weighted magnetic resonance imaging (MRI). All these findings are compatible with those of manganism, and are remarkably different from that in PD.</P>

차량 총중량(G.V.W) 변화에 따른 자동변속기의 누적 손상도 변화에 관한 연구

김종철(Jongchul Kim),김성환(Sunghwan Kim),김연규(Yunkyu Kim),이희용(Heeyong Lee) 한국자동차공학회 2017 한국자동차공학회 부문종합 학술대회 Vol.2017 No.5

Effects of the 2018 heat wave on health in the elderly: implications for adaptation strategies to climate change

Soyeon Kim,Sang-Yub Kim,Jongmin Oh,Yeora Chae,Jongchul Park,Daesoo Kim,Young-Min Kim 환경독성보건학회 2020 환경독성보건학회지 Vol.35 No.4

There has been growing concern over the effects of heat waves on health. However, the effects of heat waves on the health of individuals in vulnerable groups have rarely been examined. We aimed to investigate the acute health effects of heat waves in elderly individuals living in rural areas and to survey their adaptation capacity. Repeated measurements of body temperature (BT), blood pressure, sleep disturbance, and indoor temperature were conducted up to six times for each of 104 elderly individuals living in rural areas of South Korea during the 2018 heat wave. Changes in BT, systolic blood pressure (SBP), and diastolic blood pressure (DBP) according to variations in indoor and outdoor temperature were analyzed using linear mixed effect models controlling for age, sex, smoking, and drug use. We also surveyed heat wave adaptation capacity, heat wave shelters, and self-reported health problems. The average indoor temperature measured during the study period was 30.5℃ (range: 22.9–38.3℃) and that of ambient temperature was 30.6℃ (range: 24.6–36.3℃). BT significantly increased with indoor and outdoor temperatures. The effect on BT was greater in elderly women and the elderly with hypertension. DBP generally decreased with increasing indoor temperature, though the correlation was only statistically significant among the elderly with hypertension. Only 22 (21.2%) individuals used air conditioners during the heat wave. Most did not use an air conditioner mainly to avoid high electricity costs. Of the participants, 58.7% reported experiencing sleep disturbance, which was the most frequent self-reported health problem. Elderly individuals living in rural areas are directly exposed to high temperatures during heat waves, and their vital signs are sensitive to increases in indoor temperature due to poor adaptation capacity. Well-designed strategies for alleviating health-related stress during heat waves are necessary.

Effect of T·G and T·T Mismatches of cis-syn Cyclobutane Pyrimidine Dimeron the Thermal Stabilities of DNA Decamer Duplexes

Hyeong-Ju Kim,Kyeong Hun Kim,Jong Hoon Kim,Su Hyun Kim,Young-Min Kang,Jongchul Bang,한상우,최병석,이준화 대한화학회 2008 Bulletin of the Korean Chemical Society Vol.29 No.4

RCP 시나리오에 근거한 고해상도 미래 풍력 기상자원 분석

임윤정(Yun-Jung Lim),김선애(Seonae Kim),장동호(Dong-Ho Jang),박종철(Jongchul Park),김연희(Yeon-Hee Kim),김백조(Baek-Jo Kim),김맹기(Maeng-Ki Kim) 건국대학교 기후연구소 2016 기후연구 Vol.11 No.1

We developed the Parameter-elevation Regressions on Independent Slopes Model(PRISM)-based Dynamical downscaling Error correction(PRIDE)-Wind speed(WS) model version 3.0 to produce highresolution(1km) grid data at a monthly time scale by using observation and Regional Climate Model(RCM) wind speed data. We consequently produced monthly wind speed grid data during the observation period(2000~2014) and the future period(2021~2100) for Representative Concentration Pathway(RCP) 2 type scenarios by using the PRIDE-WS model. The PRIDE-WS model is constructed by combining the MK(Modified Korean)-PRISM-Wind, the RCM anomaly and Cumulative Density Function(CDF) fitting, basically based on Kim et al.(2016)’s algorithm applied for daily precipitation. The upper level wind(80m altitude) was estimated by Deacon equation using surface wind speed that was produced by the PRIDE-WS model. The results show that the wind speed at the upper level generally increased during the summer season while it decreased during the spring, autumn and winter seasons.

Occurrence of Dechlorane compounds and polybrominated diphenyl ethers (PBDEs) in the Korean general population

Kim, Jongchul,Son, Min-hui,Shin, Eun-su,Choi, Sung-Deuk,Chang, Yoon-Seok Elsevier 2016 Environmental pollution Vol.212 No.-

<P><B>Abstract</B></P> <P>Dechlorane compounds, including Dechlorane Plus (DP), mirex, and Dechlorane (Dec) 602, 603 and 604, were measured in 61 serum samples collected from a Korean urban area (Seoul) in 2013. Dechlorane Plus and Dec 602 were dominant in most samples, whereas Dec 604 was not detected in any samples. The median value of DP was 0.75 ng/g lipid, which was comparable with the levels observed in Europe and Canada, but lower than that observed in China. Statistically significant correlations among Dechlorane compounds were observed. The median anti-isomer fractional abundance (<I>f</I> <SUB>anti</SUB>) was 0.74, and a negative correlation between <I>f</I> <SUB>anti</SUB> and the DP concentration in serum samples was observed. Polybrominated diphenyl ethers (PBDEs) were also measured for comparison with Dechlorane compounds, and BDE-153 was found the most abundant congener with a median value of 1.43 ng/g lipid. A time trend of Dechlorane compounds was investigated in 7 pooled serum samples to cover the period from 2006 to 2013. A distinct trend of Dechlorane compounds was not observed, while PBDEs steadily decreased with time.</P> <P><B>Highlights</B></P> <P> <UL> <LI> We investigated the occurrence of halogenated flame retardants in Korea. </LI> <LI> The concentrations of Dechlorane compounds in 7 pooled serum samples were measured. </LI> <LI> PBDEs were also measured for comparison with Dechlorane compounds. </LI> <LI> A negative correlation between <I>f</I> <SUB>anti</SUB> and the total DP concentrations was observed. </LI> </UL> </P>

Polychlorinated naphthalenes (PCNs) in seafood: Estimation of dietary intake in Korean population

Kim, Jongchul,Shin, Eun-Su,Choi, Sung-Deuk,Zhu, Jiping,Chang, Yoon-Seok Elsevier 2018 Science of the Total Environment Vol.624 No.-

<P><B>Abstract</B></P> <P>Polychlorinated naphthalenes (PCNs) were measured in 33 seafood species including fish, mollusks and crustaceans purchased from local markets in five Korean cities between 2012 and 2013. Five samples were collected from each species for the measurements. Thirty-seven PCN congeners from tetra-CN to octa-CN were measured. Octa-CN (octachloronaphthalene) was not detected in any of the samples. Tetra-CN and penta-CN were the predominant homologues of PCNs in seafood samples with PCN 51 and PCN 52/60 being the most abundant congeners in the samples. Total PCNs concentrations and their corresponding dioxin-like toxic equivalent (TEQ) values ranged from non-detection (ND) to 110pg/g on a wet weight (ww) basis and from ND to 0.14pg-TEQ/g ww, respectively. The estimated daily intake of total PCNs based on an absolute content and TEQ potency were estimated for the Koreans to be 570pg/day and 0.44pg-TEQ/day, respectively. However, the estimated TEQ value of PCNs intake from seafood, represented only a small fraction (3.0%) of the total TEQ intake from consumption of seafood in Korean population. This is the first report to exhibit the presence of PCNs in seafood samples collected from local markets in Korea and their intake by general population.</P> <P><B>Highlights</B></P> <P> <UL> <LI> First report on PCNs in seafood samples purchased from local markets in Korea </LI> <LI> Calculation of toxic equivalency (TEQ) of PCNs in seafood samples </LI> <LI> Estimation of both daily intake of PCNs and TEQ values in Korean general population </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Levels of polybrominated diphenyl ethers in the Korean metropolitan population are declining: A trend from 2001 to 2013 : Levels of PBDEs in Korean population are declining

Kim, Jongchul,Kang, Jung-Ho,Choi, Sung-Deuk,Zhu, Jiping,Chang, Yoon-Seok Wiley Blackwell (John Wiley Sons) 2018 Environmental toxicology and chemistry Vol.37 No.9

Efficacy of New Image Processing Method in Renal Volume Measurement using Abdominal computed Tomography

Kim, Jongchul 충남대학교 의과대학 의학연구소 2002 충남의대잡지 Vol.29 No.1

복부 전산화 단층 촬영을 이용한 저자들의 새로운 디지털 영상 자료 처리 기법이 임상적으로 인체의 신장 용적 측정에 얼마나 유용한지, 그 효용성에 대해 알아보는 것이 본 연구의 목적이다. 본원 진단방사선과에서 진단 목적으로 복부전산화 단층 촬영을 시행한 환자 중에서 신장이 정상으로 판정된 총 10명을 대상으로 하였다. 전산화 프로그램을 이용하여 단일 절편 내에서 신장 부분을 분절화 하는 과정과, 처리된 절편들을 겹침 방식으로 한꺼번에 처리하여 남은 잡음을 제거하는 두 가지 과정을 통해 신장을 분절화하였다. 절편 사이의 간격과 영상을 구성하는 화소들의 크기에 대한 정보를 이용하여 신장의 체적을 산출하였다. 이러한 방법으로 산출된 체적을 진단방사선과 전문의의 수작업을 통한 분절화로 산출된 체적과 비교해 보았다. 신장의 복부 전산화 단층 촬영에서 프로그램과 수작업에 의해 산출된 신장 평균 체적을 비교한 결과, 약 1.7%의 오차를 보였다. 본 연구에서 사용된 새로운 디지털 영상 자료 처리 기법은 복부 전산화 단층 촬영에서 신장을 자동적으로 분절화하고 체적을 산출하는데 있어서 정확하고 유용한 방법이었다. 신장의 자동 인식, 손실 부분의 복구, 완벽한 잡음제거 등을 해결하기 위한 연산법의 개선과 함께, 향후 이러한 방법을 진단 및 치료방사선과 영역에서 임상적으로 활용하는데 대한 추가적인 연구가 필요할 것으로 생각된다. The purpose of this study was to evaluate the usefulness of new digital image processing method in renal volume measurement using abdominal computed tomography for clinical application. Computed tomography of normal kidney in 10 patients was processed. We extracted kidney in a single slice using the character of pixel distribution of the kidney, and we removed the residual noise using batch processing with folding method. And then, we determined the volume of kidney using the information of slice thickness and pixel size. Finally we compared the determined volume by this digital imaging processing method with volume calculated by manual method. The error rate on computed tomography of kidney was less than 1.7% between the volume by the image proceeding program and the volume calculated by manual method. The new digital image processing method used in this study was exact and useful for automatic segmentation and volume determination of kidney using abdominal computed tomography. We suggest that further study is needed to improve the algorithm and to practice clinically in the area of therapeutic and diagnostic radiology.

RELATIONSHIPS AMONG BPL, ORGANIZATION IMAGE, ORGANIZATION REPUTATION, EMPLOYMENT BRAND EQUITY AND INTENTION TO PURSUE JOB OPPORTUNITY IN R.O.K NAVY

Jongchul Na,Sang Jin Kim,Kyung Hoon Kim,Huanzhang 글로벌지식마케팅경영학회 2016 Global Marketing Conference Vol.2016 No.7

In 2015, the movie “Northern Limit Line” which based on the naval battle of South and North Korea occurred in 2002 was premiered (Los Angeles Times, 2016). This movie made a significant contribution to improve the image of the R.O.K Navy. Brand Placement (BPL) was used to promote the R.O.K Navy in this movie (Karrh, 1994; Van Reijmersdal, Neijens & Smit, 2007). The R.O.K. Navy is trying to build powerful naval forces with the slogan called “The Ocean Navy”. It is essential to acquire the elite military forces who can help the Korean Navy to accomplish its strategic goal and heighten the competitiveness. The acquired elite military forces are expected to demonstrate their own ability while they serve the R.O.K. Navy. They will have positive influences to the local communities as the supporters of the R.O.K. Navy after they are discharged. This research analyzed BPL effect in terms the recruitment of workforce. This research identified the relationship among BPL, organization image, organization reputation, employment brand equity and intention to pursue job opportunity in R.O.K Navy. In previous researches, the effect of image can be applied to corporate brands, product, individual brands, geographical areas, events and people (Balmer, 1997). The image of organization can remind people of the particular organization (Cable & Yu, 2006). The reputation is a dynamic interaction construct with the image, and defined as a subjective judgment based on the reliability and integrity about the organization in long term (Clardy, 2012). Employment brand equity is defined as outcome of applicant’s decision choices attributable to job seeker’s beliefs about the organization as employer(Han & Collins, 2002). Marketing literatures on employment brand equity can be useful in helping to understand how job seeker develops beliefs about organization as employer. Although many researches studied BPL, organization image and reputation, employment brand equity, etc., little researches have been conducted to integrate the variables mentioned above in public sector such as the military forces. Samples of this research consist of people who watched the movie called “Northern Limit Line”. SPSS and AMOS package programs are employed to analyze the data. Marketing strategy for a public sector such as Korean Navy based upon the results of the findings from this study is expected to position Korean Navy as more efficient and effective organization to recruit better quality human resources.