초피 용매 추출물의 항산화성 및 항균성에 관한 연구

안명수,원종숙,김현정,한미남 한국식생활문화학회 2004 韓國食生活文化學會誌 Vol.19 No.2

The antioxidative and antimicrobial activity were carried on the Chopi(Zanthoxy1um pippentum) extracts by six kinds of solvents in order to find out new natural food additives. Six solvents were used methano(MeOH), n-hexan(hexane), chloroform(CHCl_(3)), ethylacetate(EtOAc), buthano(BuOH), and water(water and methoanol extract(MEex), hexan extract(HEex), chloroform extract(CHex), ethylacetate extract(EAex), and buthanol extract(BUex), water extract(WAex). The antioxdative activities of them extracts were determined by peroxide value(POV), conjugated diene value(CDV) of corn germ oil storaged for 30 days at 60±2℃. These extracts were added as 0.02, 0.1, 0.2% of each extracts and compared with a-tocopherol, and BHT. The antioxidative activities of 0.02% extract were as follows in decreasing order BUex >WAex, BHT, MEex>HEex, EAex, CHex>TOC, and control. While, BUex and CHex among these extracts were shown to be had antimicrobial effects on the microorganism such as Escheria coli, Salmonella typhimurium, Psedomonas aeruginosa, Staphylococcus aureus, and Listeria monocytogenes. Finally to find out the preference of chopi we had made Yugwanzageon (a kind of shallow fried meat ball )by adding chopi powder. The result were similar to control( not added chopi powder ) in case of 0.1% chopi adding Yugwanzageon . (p<0.05) therefore it was thought to be possible that chopi powder was used Yugwanzageon preperation.

脈象形成에 對한 基礎的 硏究

安圭錫,朴鍾鉉 대한동의병리학회 1993 동의생리병리학회지 Vol.8 No.-

연구배경 : 맥진은 고대로부터 장기간에 걸쳐 임상경험을 통하여 축적되고 체계화 되어 이루어진 진단법으로, 한의학의 변증시치에 있어서 필수불가결한 객관적 근거로 인정받고 있다. 맥상을 분석하여 인체에서의 상황을 판단하려면 맥현상에 대한 기본적인 이해가 선행되어야 할 것으로 보여 맥상 형성에 대한 기초적 연구를 하고자 하였다. 방법 : 맥에 대한 한의학 문헌을 근거로 하고, 이를 물리학적인 혈류역학측면에서 맥상의 형성원리, 맥형성의 구성요소 및 맥상과 내외부 환경과의 관계에 대하여 연구 하였다. 결과 : 맥은 파동이며 인체 내부의 기가 맥이라는 파동의 형태로 변이되어 표출되는 간접적 반응이다. 맥상은 심장, 혈관, 혈액의 구조적 요소에 맥기의 기능적 요소가 결합하여 표현되는 것이며, 이 사자는 외내적 환경에 대한 구체적 표현이다. 결론 : 맥은 인체내외의 환경에 대한 인체내부 기의 구체적 표현이며 파동의 형태로 변이되어 표출되므로 맥진시에는 이러한 점을 염두에 두어야 할 것으로 판단된다.

함수량이 다른 오염지반의 지지력 결정

안종필,박경호,백현 朝鮮大學校 建設技術硏究所 1999 建設技術硏究 Vol.19 No.1

This study, investigates the existing theoretical backgrounds in order to examine the behavior of lateral flow owing to the plasticity of soils when unsymmetrical surcharge is worked on polluted soils by the increase of water content, compares and analyzes the results measured through model tests. Unsymmetrical surcharge is increased at regular intervals to soil tank made up the polluted soils and then the amounts of settlement, lateral displacement and upheaval are observed. Critical surcharge was decided q_(cr)=3.42 C_(u) similar to those had proposed Terzaghi and JHI, and the value of ultimate capacity was decided q_(ult)=7.71 C_(u) similar to that of Tschebotarioff and JHI

소화성 궤양에 대한 Nizatidine의 임상효과

안정기,이기천,허승식,이종선,정현용,이헌영,김영건 충남대학교 의과대학 지역사회의학연구소 1990 충남의대잡지 Vol.17 No.1

Nizatidine is a newly introduced potent H2-receptor antagonist of acid secretion with long duration of action. For evaluation of clinical efficancy and safety, twenty one patients with endoscopically proved thirteen gastric ulcers and eight duodenal ulcers were treated with nizatidine 300mg at bed time via per os for 6 weeks. The results were as follows 1. The rate of complete endoscopic healing of duodenal ulcer 92.3% and 87.5% after 6 weeks. The overall healing rate of peptic ulcer was achieved in 89.9% at 6 weeks. 2. Clinical symptoms disappeared in 84.6%, 92.3% and 100% of patients with duodenal ulcer and 75.0%, 87.5% and 87.5% patients with gastric ulcer at 2, 4 and 6 weeks respectively. 3. There were not developed any symptoms and signs suggesting side effect of drug. In conclusion, data from this study suggest that nizatidine 300mg p.o. at sleeping time is effective and safe in treatment of peptic ulcer disease, and is well tolerated on a short-term basis.

沙上地域 産業體 勞動者의 職場體育 參與擴大 方案

安永弼,鄭琮勳,鄭三鉉,金海禮,趙在基,朴俊東,金垠利,張禎允,金福善,孔庚鎬 東亞大學校附設스포츠科學硏究所 1989 스포츠科學硏究論文集 Vol.7 No.-

신장의 사춘기 성장 동안 초경 발생 시기와 성장 곡선의 형태에 관한 연구

안용수,이기수,남종현,강윤구 대한치과교정학회 2009 대한치과교정학회지 Vol.39 No.3

이 연구는 만 7세부터 17세까지의 신장의 누년적 변화를 통해서 사춘기 최대 성장기와 초경 발생 시기와의 관계를 평가하고, 성장 곡선의 형태에 따라 성장 곡선을 분류하여 각 형태별 특징을 파악하고자 시행하였다. 경기도 화성에 있는 삼괴 고등학교에서 1학년부터 3학년까지 96명의 생활기록부에 기재되어 있는 신장의 누년적인 자료가 이용되었으며, 초경 시기와 전신적 질환 유무는 설문지를 통해 조사되었다. 사춘기 성장 가속기는 9.9세에 시작하여 11.6세에 최대 성장기를 이루고 14.1세경에 끝났다. 초경은 12.6세에 일어나며 76.1%는 최대 성장기 이후에 나타나고 최대 성장기와는 1년의 차이를 보인다. 10.4%에서 최대 성장기 전에 초경이 나타났고 13.5%에서는 최대 성장기와 동일한 시점에 나타났다. 초경 시기와 관계없이 사춘기 성장 가속 기간은 4.2년으로 일정하게 나타난다. 성장 곡선을 4가지 형태로 분류하였으며, A형은 51.1%, B형은 21.9%, C형은 20.8%, D형은 6.2%의 분포를 보인다. C형의 성장 가속 기간이 가장 길게 나타난다. B형과 C형에서 PHV가 두 개인 경우는 B형과 C형의 58.5%인 24명에서 나타났다. 이상의 연구 결과에서 개개인의 성장 양상은 개인차가 크며 초경뿐만 아니라 누년적인 성장을 참고로 하여 onset의 정확한 시기와 성장 곡선 형태를 파악할 수 있다면 남은 성장 기간 예측에 도움을 줄 것으로 생각된다. Objective: This study investigated the onset, peak height velocity (PHV) and end of adolescent growth spurt as well as menarcheal timing deduced from surveying accumulative height growth over many years. Methods: Ninety six students of Samgoe high school between 1st and 3rd grade that were in good health participated in the research. A survey questionnaire was distributed to examine the students’ health status and menarche timing. Results: Adolescent growth spurt typically began at the age of 9.9 and reached a PHV at the age of 11.6. The growth spurt ended at the age of 14.1 on average. The average age of menarche was 12.6 years, which was about one year after the PHV of adolescent growth spurt. In most cases, menarche came after PHV. But in 24% of the students, menarche and PHV was nearly coincident or menarche preceded PHV. The growth curves were classified into four types. A typical adolescent growth spurt showed one PHV on graph that drastically drops after the PHV. However, there were cases with two PHVs. Conclusions: The results indicate that individual growth patterns show large individual differences, however the categorization into the various growth curves may aid in predicting individual growth patterns.

당뇨병성 신경병증에서 근위부 비골신경전도 검사를 이용한 병태생리학적 접근

김동현,이강건,박종원,박태환,안병철,권오상 대한신경과학회 1998 대한신경과학회지 Vol.16 No.2

자기장 저속 냉동보관법을 이용한 쥐 치아 치주인대세포의 활성도 검사

안현정,김의성,김진,김덕원,김기열,이찬영,이승종 大韓齒科保存學會 2008 Restorative Dentistry & Endodontics Vol.33 No.4

본 연구의 목적은 흰쥐 상악 대구치를 발거하여 자기장 저속 냉동보관법을 이용하여 냉동 시 치주인대세포의 활성도 및 세포 사멸도를 MTT검색법과 TUNEL검사를 이용하여 측정하고자 하였다. 4주령의 암컷 Sprague-Dawley계 된 쥐의 상악 좌우 제1,2대 구치를 발거하여 각군 당 12개의 쥐 치아를MTT검색에 이용하였고 6개의 치아를 TUNEL 검사에 이용하였다. 실험군은 5개군으로 대조군은 즉시 발치군이며 4℃냉장고에서 1주일간 보관한 냉장군, 발치 후 동해방지제 처리과정을 거쳐 -196℃의 액화질소에 넣어 급속 냉동한 액화질소군, 21.7 ㎃, 60 ㎐, 1 G의 자기장을 이용하여 -0.3℃/min 의 속도로 -20℃까지 냉동 후 -196℃로 급속 냉동한 자기장군, -0.3℃/min의 속도로 -20℃까지 냉동 후 -196℃에 급속 냉동한 저속 냉동군으로 나누었다. 보존액은 F medium을 사용했으며 동해방지제로 10% dimethyl sulfoxide (DMSO)를 사용하였다. 치근면을 단위면적으로 표준화하기 위해 MTT측정값을 Eosin 염색 후 530 ㎜에서 측정한 흡광도 값으로 나누었다. TUNEL 검사 시 각 조직슬라이드에서 400배 크기의 현미경 시야에서 임의로 세 부분을 지정하여 정상 세포수와 양성 세포수를 세어 그 비율을 계산하여 각 실험군 당 평균치를 구하였다. 통계 분석을 위해 one way ANOVA를 시행하였으며 사후검정으로 Scheffe와 Tukey HSD방법을 썼으며 결과는 다음과 같다. MTT검색에 의한 흡광도를 Eosin염색 후 측정한 흡광도로 나눈 값에서는 자기장군은 즉시 발치군보다 낮은 세포활성을 보였고 (p < 0.05) 액화질소군, 저속 냉동군과는 통계적으로 유의성 있는 차이를 보이지 않았다. 그러나 자기장군은 액화질소군, 저속 냉동군과 함께 냉장군보다는 높은 세포 활성도를 보였다 (p<0.05).TUNEL검사 결과도 자기장군은 즉시 발치군보다 치주인대의 세포사멸도가 높았으나 (p < 0.05) 저속 냉동군과 액화 질소군과는 통계적으로 유의한 차이를 보이지 않았다. 자기장군은 냉장군보다 세포사멸도가 낮았으며 냉장군은 모든 군 중에서 세포 사멸도가 가장 높았다 (p<0.05). The purpose of this study was to evaluate the viability of periodontal ligament cell in rat teeth using slow cryopreservation method with magnetic field through MTT assay and TUNEL test. For each group, 12 teeth of 4 weeks old white female Sprague-Dawley rat were used for MTT assay, and 6 teeth in TUNEL test. The Maxillary left and right, first and second molars were extracted as atraumatically as possible under tiletamine anesthesia. The experimental groups were groupl (immediately extraction), group 2 (cold preservation at 4℃ for 1 week), group 3 (rapid Cryopreservation in liquid nitrogen), group 4 (slow cryopreservation with magnetic field of 1 G), and group 5 (slow cryopreservation). F medium was used as preservation medium and 10% DMSO as cryoprotectant. After preservation and thawing, the MTT assay and TUNEL test were processed. One way ANOVA and Scheffe method were performed at the 95 % level of confidence. The value of optical density obtained after MTT analysis was divided by the value of eosin staining for tissue volume standardization. In both MTT assay and TUNEL test, it had showed no significant difference among group 3,4, and 5. And group 3 had showed higher viability of periodontal ligament cell than group 2. From this study, slow cryopreservation method with magnetic field can be used as one of cryopreservation methods.

防潮堤의 壓密沈下量 解析에 관한 考察

安鍾弼,朴吉鉉,金永先 조선대학교 국토개발연구소 1988 국토개발연구 Vol.8 No.1

In Seadyke design a surface stress Calculation using osterberg chart for few point has been generally used to settlement quantity Computation. This study is developed to the Computer Program of integral formula having a Zonal triangular load, A few Case studies are examinedand find out degree of error about the Cross section. This results can be use to the seadyke design.

정중운동신경과 척골운동신경의 전기생리학적 연구

김종순,이현옥,안소윤,구봉오,남건우,김영직,김호봉,류재관,류재문 대한정형도수치료학회 2005 대한정형도수물리치료학회지 Vol.11 No.2

The determination of peripheral nerve conduction velocity is and important part to electrodiagnosis. Its value as neurophysiologic investigative procedure has been known for many years but normal value of median and ulnar motor nerve was poorly reported in Korea. To evaluate of median and ulnar motor nerve terminal latency, amplitude of CMAP(compound muscle action potential), conduction velocity and F-wave latency for obtain clinically useful reference value. 71 normal volunteers(age,19-65 years;142 hands) examined who has no history of peripheral neuropathy, diabetic mellitus, chronic renal failure, endocrine disorders, anti-cancer medicine, anti-tubercle medicine, alcoholism, trauma, radiculopathy. Nicolet Viking Ⅱ was use for detected terminal latency, amplitude of CMAP, conduction velocity and F-wave latency of median and ulnar motor nerve. Data analysis was performed using SPSS. Descriptive analysis was used for obtain mean and standard deviation, independent t-test was used to compare between Rt and Lt side also compare between different in genders. The results are summarized as follows: 1. Median motor nerve terminal latency was right 3.00ms, left 2.99ms and there was no significantly difference between right and left side and genders. 2. Median motor nerve amplitude of CMAP was right 17.26mV, left 17.50mV and there was no significantly differences between right and left side and genders. 3. Median motor nerve conduction velocity was right 57.89m/sec, left 58.03m/sec and there was no significantly difference between right and left side and genders. 4. Median motor nerve F-wave latency was right 25.74ms, left 25.59ms and there was significantly differences between genders. 5. Ulnar motor nerve terminal latency was right 2.38ms, left 2.45ms and there was significantly differences between right and left side. 6. Ulnar motor nerve amplitude of CMAP was right 15.99mV, left 16.02mV and there was no significantly differences between right and left side and genders. 7. Ulnar motor nerve conduction velocity was right 60.35m/sec, left 59.73/sec and there was no significantly differences between right and left side and genders. 8. Ulnar motor nerve F-wave latency was right 25.53ms, left 25.57ms and there was significantly differences between genders.