하지수술시 Fentanyl과 병용한 0.75% 등비중 Ropivacaine을 이용한 척추마취

임일환,이상곤,반종석,민병우 대한마취과학회 2002 Korean Journal of Anesthesiology Vol.43 No.5

Background: Opioids and local anesthetics administered together intrathecally have a potent synergistic analgesic effect and less hypotention using a minidose of local anesthetic. This study was designed to investigate the safety and efficacy of two doses of intrathecal isobaric ropivacaine/fentanyl in patients undergoing an operation of the lower extremities. Methods: Thirty patients undergoing an elective orthopedic surgical operation of the lower extremities were randomly assigned to two groups for spinal anesthesia. Patients in group Ⅰ (n = 15) received 0.75% ropivacaine 14 mg/fentanyl 20㎍, and patients in group Ⅱ (n = 15) received 0.75% ropivacaine 16 mg/fentanyl 20㎍. After spinal anesthesia, we measured the time to T10, peak dermatomal level, time to peak sensory level, time to maximum motor blockade, duration of complete motor block and duration of complete sensory block using the pin prick test and Bromage motor scale. Also circulatory variables were monitored every 5 min and side effects were measured for 3 day after spinal anesthesia. Results: There were no significant differences between the groups in time to T10, peak dermatomal level, time to peak sensory level, time to maximum motor blockade and duration of complete motor block, but duration of complete sensory block was significantly longer in the 0.75% ropivacaine 16 mg/fentanyl 20㎍ group than the 0.75% ropivacaine 14 mg/fentanyl 20㎍ group. Conclusions: Intrathecal 0.75% ropivacaine 14 mg/fentanyl and 0.75% ropivacaine 16 mg/fentanyl were equally suitable for a lower extremity operation. (Korean J Anerthesiol 2002; 43: 600~605)

VOCs의 光觸媒處理에 관한 硏究

임경택,김춘희,고경숙,배병훈,문종익 동아대학교 환경문제연구소 1997 硏究報告 Vol.20 No.2

This study has been carried out to observe photodegradation efficieny of TCE with the variation of IN irradiation strength, liquid thickness and immobilized TiO₂. The results are summarized as fallows; 1. Without photocatalyst, the TCE removal efficiency was observed to be about 15% with UV irradiation. 2. Above 93% of TCE were mineralized by immobilized TiO₂on glass panel(5g, 500℃) and UV irradiation. The photodegradation efficiency increased with increasing UV lamp numbers and reaction rate increased with increasing TCE initial concentration. 3. The photodegradation efficiency decreased with increasing the liquid thickness and above 96% of TCE were removed with using 3 UV lamps and liquid thickness less than 6cm.

복식전자궁적출술 후 경막외 통증 관리시 0.1% Bupivacaine/Morphine과 0.1% Ropivacaine/Morphine의 비교

임일환,문철준,반종석,민병우 대한마취과학회 2002 Korean Journal of Anesthesiology Vol.43 No.5

Background: Local anesthetics combined with an opioid are frequently used as a postoperative epidural analgesia, to minimize individual doses and to reduce unwanted side effects. The aims of this study were to compare analgesic effectiveness, occurrence of motor block and other side effects of a 48 hr postoperative continuous epidural infusion of 0.1% bupivacaine/morphine or 0.1% repivacaine/morphine. Methods: Forty female patients scheduled for an elective total abdominal hysterectomy under general anesthesia were randomized in a double-blind fashion to receive either 0.1% bupivacaine with 0.02 mg/ml morphine or 0.1% ropivacaine with 0.02 mg/ml morphine using a continuous epidural analgesia pump at a rate of 4 ml/hr during the postoperative 48 hours. After toe operation, we assessed the blood pressure, heart rate, visual analog scale (VAS), side effects, additional analgesic requirement and time to ambulation for 48 hours in 12-hour intervals. Results: There were no significant differences in VAS on rest and cough between the groups, but VAS on deep breathing and position change were significantly lower in the bupivacaine group compared to the ropivacaine group. Side effects were similar in both groups except paresthesia. Time to ambulation was earlier in the ropivacaine troup compared to the bupivacaine group. Conclusions: Both the postoperative continuous epidural infusion of 0.1% bupivacaine with morphine and 0.1% ropivacaine with morphine provided similar pain relief and side effects. However, earlier recovery of ambulation in patients receiving ropivacaine/morphine will improve outcome after abdominal surgery. (Korean J Anesthesiol 2002; 43: 633~639)

Wegener 씨 육아종 증례보고 1예 : A Case Report

정선관,임형근,정은택,노병석,김창근,원종진 圓光大學校 醫科學硏究所 1995 圓光醫科學 Vol.11 No.2

Wegener's granulomatosis is characterized by necrotizing and granulomatous disease which involves upper, lower respiratory tract and kidney. The basic pathophysiologic mechanism of Wegener's granulomatosis is still unknown. We report a case of Wegener's granulomatosis which involved lung and pleura and was diagnosed by clinical symptoms, radiologic findings and anti-neutrophilic cytoplasmic autoantibodies.

지능형 정속주행 제어시스템 개발

임영도,설재훈,한창훈,김승철,박종오,이준탁,방석원 東亞大學校 附設 情報通信硏究所 1998 情報通信硏究所論文誌 Vol.6 No.1

This paper describes an intelligent cruise control system for automobile. With the remarkable numericalincrease of automobiles on the roal, the optimized traffic flow control using the cruise control is one of the very important traffic problems to overcome the limitation of an existing road capacity. Based onthis idea that minimize the fuel cost and teh air pollution, and accept a driver's needs for driving, we have developed an intelligent cruise control system for vehicle. This proposed intelligent fuzzy cruise controller was successfully implemented using the fuzzy algorithm, the i80c196 μ-controller board and the throttle valve actuator. The field test results on an linear road was introduced.

(6S, 7S)-Trans-Laurediol의 합성 연구

강석구,임종석 성균관대학교 1992 論文集 Vol.42 No.2

2-데옥시-D-리보스를 출발물질로 하여 2,3-이소프로필리덴디옥시 알데히드의 염기조건에서의 에피머화 반응을 주요 반응 단계로 하여(6S, 7S)-trans-Laurediol을 합성하였다. A synthesis of (6S, 7S)-trans-laurediol starting from 2-deoxy-d-ribose using the epimerization reaction of 2,3-isopropylidene aldehyde with treatment of base is described.

초, 중학생 및 급식 담당 영양사를 대상으로 한 버섯의 인식 및 이용형태에 관한 연구

이종숙,이경아,주영철,임갑준,이재성 한국식생활문화학회 2004 韓國食生活文化學會誌 Vol.19 No.3

A study on the recognition on the mushrooms by elementary school pupils, middle school students and school dietitians were-carried out. The ways of cooking mushrooms by school dietitians were also investigated. Most students and dietitians highly recognized mushrooms as good food. The most favorite mushroom was Flammulina velutipes, the cooking of mushrooms with meat and the hot mushroom soup with meat(Jungol) being the most preferred cooking methods. School ditetitians like to use mushrooms in school lunch and generally use medium or high quality mushrooms. Students, however, do not tend to prefer mushrooms compared to other vegetables. Mushroom dishes that can promote the consumption by students are mushroom bulgogi, mushroom pizza, sweet and sour mushroom in the order.

대퇴골 전자간 골절의 압박나사못 고정술 치료에서의 원위 골절부 위치의 중요성

라종득,박현수,박영봉,임창석,김승우 대한골절학회 2003 대한골절학회지 Vol.16 No.4

RAW264.7 세포에서 interferon-r 및 LPS에 의해 유도되는 NO생성에 미치는 TALT-35의 영향

박종일,박경석,김종석,박지훈,윤은진,송경섭,서강식,김훈,윤완희,박승길,임규,황병두 충남대학교 생물공학연구소 2006 생물공학연구지 Vol.12 No.-

TALP-35 purified from human term placenta is known to increase microtubule polymerization and stabilize the polymerized microtubule. To examine the effect of TALP-35 on immune system this study was performed. MTT assay was performed to investigate the effect of TALP-35 on the proliferation of RAW264.7 cells. TALP-35 dose dependently suppress the proliferation of RAW264.7 cells at high concentration (above 1 μM) in unstimulated cells, in case of 10 μM TALP-35 treated cells the suppression was 25% but in stimulated cells it was only 15%. Cosedimentation assay was carried out to investigate whether TALP-35 can bind to tubulin of RAW264.7, monocyte/macrophage lineage of mouse, and polymerize it. TALP-35 polymerize the tubulin of RAW264.7 cells and sedimented in dose-dependent manner. To investigate the effect of TALP-35 on the expression of iNOS protein western blotting was performed. The expression level of iNOS was decreased dose dependently in high concentration of TALP-35 treatment. To examine the activity of iNOS, secreted NO was determined by method based on Griess reaction. Interferon-γ and LPS-stimulated production of NO from RAW264.7 cells was decreased dose dependently above 0.1 μM concentration of TALP-35 and 50% is decreased at 10μM of it. This study shows TALP-35 can control cytokine induced-iNOS expression therefore it might control inflammatory diseases.

月流出量 推定모델의 決定에 關한 硏究

조정석,김기대,임채문,김종인 대구대학교 산업기술연구소 1985 産業技術硏究 Vol.4 No.-

This study is aimed at the establishment and examination of deterministic model and stochastic model to monthly streamflow. In this study, the stream morphological characteristics of the Nakdong river basin, which is one of the major basins of Korea, was determined quantitively by the topographical map. In the analysis, monthly streamflow records of Nakdong river(Dongchon, Nakdong and Jindong) were used. Modelling processes are summarized as follow; from a simplified equation of water balance on a watershed a regression model for monthly streamflow using the variables of rainfall, pan evaporation, and previous-month rainfall was formulated. And predictions were derived from the stepwise regression analysis of watershed characteristics. It was also possible to explain geographic influences on streamflow through those pridiction equation. In the stochastic processes, monthly streamflows were simulated by the Thomas Fiering model and Hamonic model.