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조준식,송창준,김종철,이병철 충남대학교 의과대학 지역사회의학연구소 1994 충남의대잡지 Vol.21 No.2
Purpose : We evaluated the usefulness of dynamic CT during portal phase with faster injection rate of contrast material in detecting hepatic metastases from gastric cancers. Subjects and Methods : We retrospectively analyzed two-phase dynamic CT findings (portal phase and equilibrium phase) in 17 patients with pathologically proven gastric cancers and hepatic metastases. In 13 patients, a total of 150ml of nonionic contrast material was administered with a power injector at a flow rate of 5ml/sec for 30 sec, and two-phase images were obtained at 45-70 sec (portal phase) and 2-4 min (equilibrium phase) after the start of bolus injection. In four patients, two-phase dynamic CT with spiral technique was performed with the same method. Results : In cases of metastases less than 1 cm in diameter, 65 lesions were detected in the portal phase that showed clearly defined hypodense lesions in highly enhanced hepatic parenchyma. Whereas, only nine (14%) lesions were detected in the equilibrium phase and the remaining 56(86%) lesions showed isoattenuation. In cases of metastases more than 1 cm in diameter, 37 lesions were detected in the portal phase that showed clearly defined hypoattenuations. whereas, the images of equilibrium phase showed isoattenuation in five (14%), mixed attenuation in three (8%), and hypoattenuation in 29 (78%). The lesions detected in the equilibrium phase showed poorly defined hypodense lesions and tended to decrease in size due to peripheral enhancement of lesions. Conclusion : Dynamic CT during portal phase with faster injection rate of IV contrast material is an useful technique in detecting hepatic metastases from gastric cancers, particularly small lesions less than 1 cm in diameter.
소화성궤양에 (消化性潰瘍) 대한 Centella asiatica 정량추출물 (定量抽出物) ( Madecassol ) 의 치료효과
이종철,최규완 ( Jong Chull Rhee,Kyoo Wan Choi ) 대한소화기학회 1981 대한소화기학회지 Vol.13 No.1
The Purpose of this paper is to evaluate the clinical efficacy of the titrated extract of Centella asiatica (TECA: Madecassol) in patients with peptic ulcer. Nineteen patients with gastric ulcer and thirteen patients with duodenal ulcer were given 60mg a day, P.O. and 20mg, I.M., 3 times a week of TECA and were followed up by gastroscopy at 4, 6, 8, and 10 weeks of treatment. The observed results are as followed: 1) Six (31. 6%) out of 19 cases of gastric ulcers were completely healed off by 4 weeks, 14 (73, 7%) by 6 weeks, and 17 (89. 5%) by 8 weeks of treatment. One case was not healted up to 10 weeks of treatment. 2) Five (38. 5%) out of 13 cases of duodenal ulcers were completely healed off by 4 weeks, 9 (69. 2%) by 6 weeks and 11 (84. 6%) by 8 weeks of treatment. One case was resistant to the treatment up to 10 weeks of observation. 3) There was no untoward side reaction, either subjective or objective, to the administration of the drug.
소화성궤양의 치료에 관한 연구 : 공격인자 억제제와 방어인자 항진제의 합병투여의 효과
박영태,이종철,송인성,최규완 ( Young Tae Bak,Jong Chull Rhee,In Sung Song,Kyoo Wan Choi ) 대한소화기학회 1981 대한소화기학회지 Vol.13 No.1
The purpose of this study was to evaluate the therapeutic effect of defensive factor promotors in combination with H, receptor antagonist in peptic ulcer treatment. A prospective study was conducted on the open trial basis with consecutive method of medication. Diagnoses of total 58 patients(gastric ulcer: 36, duodenal ulcer: 22) were confirmed by gastroduodenoscopy. The patients were assigned to one of the following 3 treatment groups. Group A: 25 cases, Antacids+Cimetidine+Cetraxate, Group B: 18 cases, Antacids+Cimetidine+Sucralfate, Group C: 15 cases, Antacids Cimetidine. Each patient was followed up at 6 th week of treatment, and the therapeutic effect was evaluated. The results were as follows: Healing rates of gastric ulcers were Group A: 58. 3%, Group B: 50. 0%, Group C: 58. 3% ,,nd Total: 55. 6fc. There was no significant difference of healing rates among the groups. 2) Healing rates of duodenal ulcers were Group A: 92.3%, Group B: lpp 0%, Group C: 100. O>o and Total: 95. 5%. There was no significant difference of healing rates among the groups. But there was significant difference between gastric ulcers and duodenal ulcers. Alove results and those of previous study were compared together, and they revealed that there svas no significant difference of healing rates among the following G therapeutic groups: Antacids Cimetidine, Antacids+Cetraxate, Antacids+Sucralfate, Antacids TECA, Antacids+ Cimetidine+ Cetraxate, anrl Antacids+ Cimetidine+ Sucralfate.
Pirenzepine 의 소화성궤양치료효과에 (消化性潰瘍治療效果) 대한 임상적 (臨床的) 연구
최규완(Kyoo Wan Choi),이종철(Jong Chull Rhee),박영태(Young Tae Park) 대한소화기학회 1983 대한소화기학회지 Vol.15 No.1
N/A The purpose of this study is to assess the clinical therapeutic effectiveness and any possible side reaction of the anti-muscarinic agent, pirenzepine. The drug was given in the dose of 50 mg twice a day to 27 cases of gastric ulcer and 23 cases of duodenal ulcer. Initial diagnosis, and follow-up observations after 4 weeks, 6 weeks and 8 weeks of treatment were made by the upper G- I endoscopy. The results observed are as followings: 1. The male to female ratio of the subjects was about 4: 1 and the most prevalent age group was the fifth decade of the life in both the gastric and duodenal ulcer groups. 2. As for the subjective symptoms, postprandial discomfort, burning sense and hunger pain were experienced in 47 cases (85.5%), 42 cases (76.4%) and 36 cases (65.5%) respectively, and were completely relieved after 4 weeks of treatment in 35 cases (74.5%). 40 cases (95.2%) and 33 cases (91.7%) respectively. 3. The cumulative rates of complete healing of the gastric ulcers (27 cases) were 63.0% (17 cases) after 4 weeks, 74. 10% (20 cases) after G weeks, and 77. 8,o (21 cases) after 8 weeks of treatment, and those of the duodenal ulcers (28 cases) were 71.4% (20 cases) after 4weeks , 78.6% (22 cases) after 6 weeks, and 89.3% (25 cases) after 8 weeks of treatment 4. As for the untoward side effects associated with administration of the drug, diarrhea, dry mouth, flatulence, and constipation were noted in 12,5,3 and 2 cases respectively. However in none of these cases the symptoms were severe enough to discontinue medication. In conclusion pirenzepine appears to be effective and safe for the treatment of patients with peptic ulcer diseases.
환경온도와 우모피복도가 닭의 에너지대사에 미치는 영향 2 . 사료급여시의 에너지 대사
고용균(Yong Gyun Goh),고종태(Jong Tae Goh),이영철(Yong Chull Rhee) 한국축산학회 1987 한국축산학회지 Vol.29 No.10
Effect of environmental temperature and defeathering (DF) on the energy metabolism of cockerels was examined and results obtained are as following. 1. Environmental temperature (ET) affected heat production (HP) during feeding condition. Under 25℃ ET, HP per ㎏ metabolic body weight (MEW) were decreased with increasing ET, which is showing 146.4, 131.5, 115.9 and 88.8 Kcal under S, 15, 25 and 35℃ ET, respectively. 2. Mean HP per ㎏ MEW were respectively 120.6, 131.2 and 188.0 Kcal for 0, 50 and 100% DF treatment which is revealing the increasing HP with increasing DF level. 3. Metabolizable energy requirement for maintenance (MEm), which were 143.3, 120.6, 111.0 and 86.7 Kcal/MBW with respective ET of 5, 15, 25 and 35℃, were decreased with increasing ET. There were increased in MEm with increasing DF level under 25oC. There were 115.4, 126.6 and 192.1 Kcal for cockerels with DF level of 0, 50 and 100, respectively. However, no such difference was observed under 35℃ ET. 4. No effect of ET on Net availability of metabolizable energy (NAME) was observed. However, in average, the marginal decrease of NAME which were 66.6, 64.5 and 57.6% was shown with increasing level of DF, which respectively were 0, 50 and 100%. Effect of DF level was not observed exceptic ally under 35℃ ET.
대상포진 후 발생한 구진 고리육아종 Isotopic 반응
김성민 ( Seong Min Kim ),이승용 ( Seung Yong Lee ),이진호 ( Chin Ho Rhee ),이종선 ( Jong Sun Lee ),윤석권 ( Seok Kweon Yun ),김한욱 ( Han Uk Kim ),임철완 ( Chull Wan Ihm ) 대한피부과학회 2008 대한피부과학회지 Vol.46 No.6
Isotopic response describes the occurrence of a new skin disorder on the site of another, unrelated, and already healed skin disease. The most common cause of isotopic response in the skin is the herpes zoster virus. Variable cutaneous lesions including granulomatous reactions may occur at sites of herpes zoster infections. We report a case of papular granuloma annulare occurring on the site of herpes zoster. (Korean J Dermatol 2008;46(6):818∼820)
기능성 소화불량증 환자에서의 Electronic Barostat을 이용한 위 팽창 반응에 관한 연구
이규택(Kyu Taek Lee),손희정(Hee Jung Son),이종균(Jong Kyun Lee),이준혁(Joon Hyeok Lee),이풍렬(Poong Lyul Rhee),김재준(Jae Jun Kim),고광철(Kwang Cheol Koh),백승운(Seung Woon Paik),이종철(Jong Chull Rhee),노재형(Jae Hyung Noh),최성호(S 대한소화기학회 1997 대한소화기학회지 Vol.29 No.2
N/A Background/Aims: A decreased perception threshold of gastric distension has been observed recently in selected patients with functional dyspepsia(FD) in the absence of changes in gastric compliance. The sensations induced by changes in intragastric pressure and volumes have been shown to be independent of gastric emptying times. In Korea, there has been no report about the response to gastric distension using electronic barostat in patients with FD. Thus, we aimed to evaluate whether decreased perception threshold to the gastric distension could be one of the pathogenic factors in FD. Methods: Thirty patients with dysmotility-like FD(9 men and 21 women; age range, 27-57 years) and 20 healthy individuals without gastrointestinal symptorns(10 men and 10 women; age range, 20-54 years) were included in this study after receiving written informed consent. We measured intragastric minimal distending pressure(MDP), gastric compliance, aMominal discomfort level, and gastric emptying rate of solid meal. We used a dual drive barostat (G&J Electronics, Canada) and biad gamma camera(Trionix). MDP was defined as the first pressure level to inflate an intra gastric bag volume > 30mL. And then, symptoms and volume of the intragastric bag, which was inflated by increasing intragastric bag pressur, was measured in 1 mmHg steps every 3 minutes, We compared gastric compliance at a low pressure zone(0-2 mmHg above MDP) and at a high preassre zone(6-8mmHg above MDP), We calculated the mean values( SD) of the parameters, and statistical comparisons were performed using tbe repeated measures ANOVA. Results: The MDP was significantly decreased in FD(3.9>1.8 mmHg) compared to the controls(5.7+ 1.7 mmHg; p<0.001). The gastric compliance(Cw) at a high pressure zone was significantly higher in FD(46.5+30.6 mL/rnmHg) compared to the control(31.3 + 15.3 mL/mmHg; p<0.05). Whereas there was no difference in compliance(C) at the low pressure zone(41.2+25.6 mL/mmHg in FD vs. 43.9+23.1 mL/mmHg in the control). Patients with FD had gastric hypersensitivity to distension(discomfort threshold at 8.3+3.8 mmHg and 392+109 mL in FD vs. 14.S+3.8 mmHg and 558+135 rnL in controls; p<0.001). There were no differences in MDP, compliance, and discomfort level according to gastric emptying times. Conclusions: We conclude that decreased perception threshold to gastric distension could be a pathogenic factor, and also an increased gastric compliance at high pressure zone may play a pathogenic role in FD. (Korean J Gastroenterol 1997;29: 135 - 144)