http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
배양 Caco-2 세포 단층막 실험계에서 트란스페린과 옥시다아제효소 포합체의 세포막투과
김동출,김지혜 충남대학교 약학대학 의약품개발연구소 1999 藥學論文集 Vol.15 No.-
Transport study of horseradish peroxidase and transferrin-horseradish peroxidase conjugate was performed using an in vivo Caco-2 cell cultured monolayer grown on a polycarbonate membrane of Transwell^ⓡ. Horseradish peroxidase was not transported across Caco-2 cell monolayer. Transferrin-horseradish peroxidase conjugate was transported through Caco-2 monolayer. The apparent membrane permeability coefficient(P_app) of transferrin horseradish peroxidase conjugate was 6.54×10^-7cm/sec in the presence of 50μg/ml brefeldin-A. These results suggest the transferrin receptor mediated transcytosis of transferrin-horseradish peroxidase conjugate across Caco-2 cell monolayer.
Alterations of Mast Cells and TGF-β1 on the Silymarin Treatment for CCl4-Induced Hepatic Fibrosis
( Dong Hwan Kim ),( Myung Hee Sohn ),( Hai Jie Yang ),( Dong Wei Yuan ),( Tae Hwan Kim ),( Kyu Shik Jeong ),( Da Hee Jeong ),( Gi Ppeum Lee ),( Won Il Jeong ),( Sun Hee Do ) 한국수의병리학회 2004 학술대회 Vol.8 No.-
Jie Dong,Rui Guo,Minjie Huang,Deqian Wang,Jiaxing Huang 한국응용곤충학회 2020 Journal of Asia-Pacific Entomology Vol.23 No.1
Chinese sacbrood virus (CSBV) is a disastrous virus that fatally threatens honeybees (Apis cerana) in China. Here, we identified the complete genome of CSBV using the rapid amplification of cDNA ends (RACE) method and compared the obtained sequences with those of other SBVs through multiple sequence alignment. The results showed that the full-length of CSBV genome from Zhejiang Province (CSBV-ZJ) is 8824 bp and contains a single, large open reading frame (ORF) that encodes 2842 amino acids flanked by 190 nucleotides (nts) of the 5′-untranslated region (UTR) and 108 nts of the 3′-UTR. The multiple genome comparison showed that SBVs have five conserved domains and that CSBV-ZJ belong to SBV type II. The phylogenetic analysis demonstrated that the CSBV-ZJ strain was similar to the CSBV from Fuzhou (CSBV-FZ) strain. Colonies collected from most of the sampling sites in the area surrounding Qiandao Lake were carriers of CSBV. The haplotypes of the VP1 gene formed a network with radiated and reticular structures. In conclusion, this characterization of the CSBV-ZJ genome will help us understand the SBV prevalence mechanism and aid the protection of honeybees.
Dong Yi Jie,Liu Zhen Hua,Zhou Jian Qiao,Zhan Wei Wei 대한영상의학회 2022 Korean Journal of Radiology Vol.23 No.4
Objective: To prospectively evaluate the efficacy of lauromacrogol injection for ablation (LIA) of benign predominantly cystic thyroid nodules and its related factors. Materials and Methods: A total of 142 benign predominantly cystic thyroid nodules (median volume, 12.5 mL; range, 0.4– 156 mL) in 137 patients (male:female sex ratio, 36:101; mean age ± standard deviation [SD], 49 ± 13 years) were treated with LIA after being confirmed as benign via cytology. The volume reduction rate (VRR) of the nodules and cosmetic score were evaluated during follow-up at 1, 3, and 6 months after treatment and every 6 months thereafter. A VRR of ≥ 50% at the 12-month follow-up was considered to indicate effective treatment. The associations between the clinical factors and nodular ultrasound features, including the initial nodule volume, proportion of solid components, vascularity grade and ineffective treatment (VRR of < 50% at the 12-month follow-up), and regrowth were analyzed. Results: All patients completed follow-up for at least 12 months. The average ± SD follow-up period was 32 ± 11 months (range, 12–54 months). The effective treatment rate was 73.2% (104/142), while the regrowth rate was 12.0% (17/142) at the last follow-up. Grade 2–3 intranodular vascularity in the solid components of the nodules was the only independent factor associated with ineffective treatment, with an odds ratio (reference category, grade 0–1) of 3.054 (95% confidence interval, 1.148–8.127) (p = 0.025). Conclusion: LIA is an effective treatment for predominantly cystic thyroid nodules. Grade 2–3 intranodular vascularity in the solid components of nodules is the only independent risk factor for ineffective LIA.
Rodenticide Poisoning in a Cocker Spaniel Dog
Hai-Jie Yang,Won-Il Jeong,Da-Hee Jeong,Sun-Hee Do,Dong-Hwan Kim,Myung-Hee Sohn,Dong-Wei Yuan,Il-Hwa Hong,Youg-Sook Son,Sang-JoonPark,Tae-Hwan Kim,Kil-Soo Kim,Keun-Woo Lee,Kyu-Shik Jeong 한국실험동물학회 2005 Laboratory Animal Research Vol.21 No.1
A dead Cocker Spaniel, a one-year-old male, was presented from a local animal hospital to the College of Veterinary Medicine, Kyungpook National University with a history of vomiting right after the ingestion of the anti-coagulant rodenticide 14 days before. At necropsy, the thorax was filled with uncoagulated blood and the thymus was markedly hemorrhagic. Hemorrhages were also found in the subcutaneous or mesenteric adipose tissues and the submucosal layers of the intestine and stomach. The spleen was atrophied. In microscopy, hemorrhages were detected in the thymus, submucose of the stomach and intestine, and adipose tissues around several organs such as the heart, kidney, and intestines. However, hemorrhages, were not detected in lungs. Centrilobular necrosis was observed in the liver. In conclusion, the cause of death was severe hemorrhages, which might have been due to the reabsorption of a small amount of anti-coagulant rodenticide that still remained in the body after vomiting. Therefore, the diagnosis was decided as intoxication with anti-coagulant rodenticide.
UASB를 이용한 혐기성 하수처리공정에서 ABF 유출수 반송에 따른 유기물질과 질소 및 인 제거
전동걸(Dong Jie Tian),변병수(Byeong Su Byun),임현숙(Hyun Suk Lim),전항배(Hang Bae Jun) 大韓環境工學會 2013 대한환경공학회지 Vol.35 No.5
UASB-ABF (Up-flow anaerobic sludge blanket-aerated bio-filter) 시스템을 이용한 하수의 혐기성처리 방법에서 질소와 인을 제거하는 공법에 대하여 연구하였다. 160일간의 UASB-ABF 시스템을 운영한 결과 유출수 반송을 통하여 TCOD뿐만 아니라, TN과 TP를 효율적으로 제거할 수 있었다. 무반송의 경우 UASB 반응조에서 유기물 제거효율은 64%에 머물었으나, 반송률 120%, 180%, 240%로 증가한 결과 각각 92%, 95%, 96%로 향상되었다. 반송률 180% 이상에서는 유기물 제거효율 증가폭은 크지 않았다. ABF 유출수 반송으로 TN 제거효율이 크게 향상되었다. TN 제거효율은 무반송 조건일 때 18%에서 82%로 향상되었으며, UASB에서 지속적인 유기물질 제거로 인하여 ABF에서 질산화효율은 안정적으로 95% 이상으로 타나났다. ABF유출수 반송으로 TP 및 PO₄3- -P 제거효율이 모두 향상되었다. TP의 경우 무반송에서는 거의 제거되지 않았으나, 반송률이 120%, 180%, 240%에서는 각각 51%, 63%, 71%로 향상되었고, 주로 UASB에서 제거되었다. Nitrogen and phosphorus removal was investigated in an UASB-ABF (Up-flow anaerobic sludge blanket - aerated bio- filter) anaerobic sewage treatment system. Successful removal of nitrogen and phosphorus with organic matters was possible in the UASB-ABF system from the results of 160 days operation with the influent raw domestic sewage. Removal efficiencies of organic matter (as TCOD) showed 64% in UASB without recycle of the ABF effluent, however, they increased to 92%, 95%, 96% with 120%, 180% and 240% recycle of the ABF effluent, respectively. Increasement of the organic matter removal was not prominent at recycle ratio above 180%. Apparent increase in TN removal occurred with recycle of the ABF effluent. TN removal efficiency was 18% without recycle, but it increased to 82% with 240% recycle of the ABF effluent. And stable nitrification above 95% was possible as a result of efficient removal of organic matter in the UASB with and without recycle of the effluent. Removal of both TP and PO₄3- -P also increased remarkably with recycle of the effluent. Without recycle of the effluent, that is at strict anaerobic condition in UASB, TP was not removed, however, its removal efficiency increased to 51%, 63%, 71% at recycle ratios of 120%, 180%, 240%, respectively mainly at UASB.