Spectrum Allocation based on Auction in Overlay Cognitive Radio Network

( Wenhao Jiang ),( Wenjiang Feng ),( Yang Yu ) 한국인터넷정보학회 2015 KSII Transactions on Internet and Information Syst Vol.9 No.9

In this paper, a mechanism for spectrum allocation in overlay cognitive radio networks is proposed. In overlay cognitive radio networks, the secondary users (SUs) must first sense the activity of primary users (PUs) to identify unoccupied spectrum bands. Based on their different contributions for the spectrum sensing, the SUs get payoffs that are computed by the fusion center (FC). The unoccupied bands will be auctioned and SUs are asked to bid using payoffs they earned or saved. Coalitions are allowed to form among SUs because each SU may only need a portion of the bands. We formulate the coalition forming process as a coalition forming game and analyze it by game theory. In the coalition formation game, debtor-creditor relationship may occur among the SUs because of their limited payoff storage. A debtor asks a creditor for payoff help, and in return provides the creditor with a portion of transmission time to relay data for the creditor. The negotiations between debtors and creditors can be modeled as a Bayesian game because they lack complete information of each other, and the equilibria of the game is investigated. Theoretical analysis and numerical results show that the proposed auction yields data rate improvement and certain fairness among all SUs.

Isoperistaltic side-to-side anastomosis for the surgical treatment of Crohn disease

Wenhao Chen,Junjie Zhou,Min Chen,Congqing Jiang,Qun Qian,Zhao Ding 대한외과학회 2022 Annals of Surgical Treatment and Research(ASRT) Vol.103 No.1

Purpose: Increasing evidence has shown an association of surgical technique, particularly anastomotic configuration, with postoperative recurrence of CD. This pilot study aimed to evaluate short-term outcomes of isoperistaltic side-to-side anastomosis (ISSA) employed on Crohn disease (CD) patients. Methods: Data were retrieved from a prospectively maintained database. Postoperatively, all patients were followed up with close endoscopic (ileocolonoscopy) surveillance. Results: From January 2017 to May 2021, 30 patients diagnosed with CD who underwent ISSA were compared with 45 CD patients who underwent antiperistaltic side-to-side anastomosis (ASSA). The 2 groups were comparable in baseline demographics and clinical characteristics. No significant differences were observed between groups regarding postoperative safety issues, including anastomotic leak, abdominal/pelvic abscess, length of hospital stay, readmission rate within 30 days, etc. At postoperative 24th month, reduced endoscopic recurrence was observed in the ISSA group compared with that in the ASSA group (18 of 24, 75.0%, . 36 of 38, 94.7%; P = 0.024). Regarding surgical recurrence, there was 0% in the ISSA group . 4.4% (2 of 45) in the ASSA group (P = 0.510). Conclusion: In this study, we aimed to explore the influence of ISSA on postoperative recurrence in CD patients, and the preliminary results show that ISSA was technically safe and feasible, and appears to be effective in reducing postoperative recurrence in CD patients. However, our conclusion was underpowered due to small sample size and inadequate follow- up. We proposed ISSA be considered as another alternative option in the toolbox of inflammatory bowel disease surgeons when performing anastomosis on CD patients.

A New Combined Support Technology to Prevent the Failure of the Existing Metro Station Induced by Unilateral Excavation

Feicong Zhou,Wenhao Fan,Ping Zhou,Mao Chen,Shougen Chen,Zhijie Wang,Yifan Jiang 대한토목학회 2023 KSCE Journal of Civil Engineering Vol.27 No.3

This study establishes a 3-D simulation model based on a real project, which reveals the problem that the metro structure deformation induced by unilateral excavation without any support exceeds the safety threshold. According to the metro structure deformation warning area, this study proposes a support technology that combines cover plate braces and diagonal steel braces. The research shows that the lateral deformation reduction ratio of the metro station under the diagonal steel brace is about 10% − 20%. The deformation reduction ratio under the cover plate brace is about 35% − 40%. To ensure construction safety, this study adopts the optimal support combination of 3 cover plates and 6+9+11 steel pipes. Monitoring feedback and simulation prediction shows that the comprehensive support system can reduce structural deformation by 56.1%, and effectively control the deformation within a safe range.

A new strategy for stem cells therapy for erectile dysfunction: Adipose-derived stem cells transfect Neuregulin-1 gene through superparamagnetic iron oxide nanoparticles

Jianxing Cheng,Zhongjie Zheng,Wenhao Tang,Jichun Shao,Hui Jiang,Haocheng Lin 대한비뇨의학회 2022 Investigative and Clinical Urology Vol.63 No.3

Purpose: Our previous studies showed that nanotechnology improves derived adipose-derived stem cells (ADSCs) therapy for erectile dysfunction (ED). In this study, the Neuregulin-1(NRG1) gene was transfected into ADSCs with superparamagnetic iron oxide nanoparticles (SPION) further to improve the therapeutic effect of ADSCs on ED. Materials and Methods: ADSCs were isolated from epididymal adipose tissue of Sprague–Dawley rats. The optimal concentration of PEI-SPION (SPION modified with polyethyleneimine) was selected to construct the gene complex. After electrostatic binding of PEI-SPION and DNA, a PEI layer was wrapped to make the PEI-SPION-NRG1-PEI gene transfection complex. Different groups were set up for transfection tests. Lipo2000 transfection reagent was used as the control. PEI-SPION-NRG1-PEI in the experimental group was transfected under an external magnetic field. Results: When the concentration of PEI-SPION was 10 µg/mL, it had little cytotoxicity, and cell activity was not significantly affected. PEI-SPION-NRG1-PEI forms positively charged nanocomposites with a particle size of 72.6±14.9 nm when N/P ≥8. The PEI-SPION-NRG1-PEI gene complex can significantly improve the transfection efficiency of ADSCs, reaching 26.74%±4.62%, under the action of the external magnetic field. PCR and Western blot showed that the expression level of the NRG1 gene increased significantly, which proved that the transfection was effective. Conclusions: PEI-SPION can be used as a vector for NRG1 gene transfection into ADSCs. PEI-SPION-NRG1-PEI packaging has the highest transfection efficiency under the external magnetic field than the other groups. These findings may provide a new strategy for ADSCs therapy for ED.

A novel NPHS2 mutation (c.865A > G) identified in a Chinese family with steroid-resistant nephrotic syndrome alters subcellular localization of nephrin

Wu Na,Zhu Yingchuan,Jiang Wenhao,Song Yue,Yin Lan,Lu Yilu,Tao Dachang,Liu Yunqiang,Ma Yongxin 한국유전학회 2022 Genes & Genomics Vol.44 No.5

Background: NPHS2 is the causative gene of nephrotic syndrome type 2 (MIM 600995) which often clinically manifests as steroid-resistant nephrotic syndrome (SRNS). The NPHS2 gene encodes a slit diaphragm (SD) associated protein podocin. Objective: This study reported a novel disease-causing mutation of NPHS2 in a Chinese family with SRNS. We also investigated the pathogenic mechanism of the variants in this family. Method: A Chinese family with SRNS was recruited. Whole exome sequencing was performed to screen for disease-causing mutation. Sanger sequencing was used to confirm the results. In vitro functional experiments including immunoblotting, co-immunoprecipitation and double immunofluorescence staining were performed to explore the pathogenic mechanisms of mutations. Results: In this family, compound heterozygous mutations of NPHS2 (c.467dupT and c.865A > G) were identified and segregated with the disease. The maternal c.865A > G was a novel variant, leading to amino acid substitution (p.K289E). In vitro functional assays indicated that c.467dupT (p.L156FfsX11) mutant lost interaction with nephrin. Both K289E and L156FfsX11 mutants showed sharply diminished plasma membrane localization. Furthermore, abnormal distribution of podocin mutants also altered the cell membrane localization of nephrin. Conclusion: We reported a family with SRNS caused by compound heterozygous mutations of NPHS2 (c.467dupT and c.865A > G). c.865A > G (p.K289E) in NPHS2 was a novel causative variant associated with SRNS. Both variants in this family not only affected the normal cell membrane localization of podocin, but also altered the cell membrane localization of nephrin which is the major architectural protein of SD.

Ultra-thin Metallized Glass Fabric Coated with Chitosan and Reduced Graphene Oxide for Electromagnetic Shielding with Excellent Heat Dissipation and Self-Cleaning

Meimei Chen,Shan Jiang,Ce Cui,Wenhao Bai,Jianyu Zhai,Ronghui Guo 한국섬유공학회 2023 Fibers and polymers Vol.24 No.8

With the rapid development of modern technology, more and more electronic equipment had entered people’s life, causing serious electromagnetic pollution. In this study, a lightweight, ultra-thin and high electromagnetic shielding film was fabricated by copper electroless deposition after solution immersion coating method combining chitosan (CTS) and reduced graphene oxide on glass fabric (Cu/RGO-CTS-coated glass fabric). Chitosan and RGO had synergistic effect for copper deposition, enhancing electrical conductivity and electromagnetic shielding property. The prepared fabric showed superb conductivity of 8589.3 S/cm and the shielding effectiveness of the Cu/RGO-CTS-coated glass fabric showed as high as 93.6 dB at ultra-thin thickness of 92.4 μm (SSE/t = 3868.8 dB cm2 g-1). Thermal conductivity, antibacterial and hydrophobic properties were also studied. Compared with untreated glass fabric, thermal conductivity of Cu/RGO-CTS-coated glass fabric increased by 437%, protecting electronic equipment from adverse effects at high temperature. Cu/RGO-CTS-coated glass fabric had inhibitory effect on Staphylococcus aureus and Escherichia coli, which could prolong the service life and maintain the appearance of the fabric. Cu/RGO-CTS-coated glass fabric also showed hydrophobicity with self-cleaning function, making it possible for the composite material to be used in many fields such as aerospace industry, microelectronic devices, and transportation to resist electromagnetic interference in high humidity and high pollution environment.

Influence of Water Molecules on Polarization Behavior and Time–Frequency Dielectric Properties of Cellulose Insulation

Wen Hao,Cheng Lin,Jiang Yi,Zhu Taiyun,Chen Zhong,Dai Xize,Gao Chenyu 대한전기학회 2021 Journal of Electrical Engineering & Technology Vol.16 No.3

Oil-immersed power transformer plays an important role in power transmission and transformation engineering. Moisture is one of the important factors to determine its insulation performance. Molecular simulation technique is used to study the mechanism of water molecules on the micro polarization behavior of cellulose insulation materials. The number of hydrogen bonds, solubility parameters, total dipole moment and polarizability are analyzed. These characteristics explain the action mechanism of water molecules on cellulose insulation. At the same time, the time domain and frequency dielectric response of cellulose insulation materials with diff erent moisture content are explored. The dielectric modulus spectrum is introduced to replace the traditional frequency dielectric spectroscopy to characterize the micro relaxation process of cellulose insulation under diff erent moisture content. Finally, the characteristic parameters are extracted from the polarization, depolarization current and dielectric modulus spectrum curves to evaluate the moisture content of cellulose insulation materials. The results show that the number of hydrogen bonds, binding energy density, solubility parameter, total dipole moment and polarizability increase with the increase of water content. It should be noted that dielectric modulus spectroscopy can eff ectively characterize the relaxation behavior of cellulose insulation materials. The moisture content of cellulose insulation can be quantitatively evaluated by DC conductivity, insulation resistance, imaginary part relaxation peak of dielectric modulus and integral value of real part and imaginary part of dielectric modulus.