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Son, Hae-Jung,Park, Ji Won,Chang, Hee Jin,Kim, Dae Yong,Kim, Byung Chang,Kim, Sun Young,Park, Sung Chan,Choi, Hyo Seong,Oh, Jae Hwan Raven Press 2013 Annals of surgical oncology Vol.20 No.9
<P>The outcomes of colorectal cancer are determined by host factors, including systemic inflammation. The purpose of this study was to evaluate the prognostic significance of fibrinogen and inflammation-based scores, as markers of the inflammatory response, in colon cancer.</P>
Son, Yo-Whan,Lee, Yoon-Young,Kim, Rae-Hyun,Seo, Kyung-Won,Ban, Ji-Yeon,Seo, Kum-Young,Koo, Jin-Woo,Kyung, Ji-Hyun,Noh, Nam-Jin The Ecological Society of Korea 2004 Journal of Ecology and Environment Vol.27 No.6
Photosynthetically active radiation (PAR) beneath the forest canopy, understory species richness and diversity, and biomass were measured in a Larix leptolepis plantation seven years after thinning in Yangpyeong. Four different thinning intensities (control, $10\%,\;20\%\;and\;40\%$ stocking reduction) were applied in 1997. The current PAR values were lower than those measured four years after thinning, and PAR at the heavy thinning plots was significantly higher than that of other thinning intensities. A total of 23 species including 9 tall-trees and 14 shrubs were found for the high layer while a total of 82 species including 10 tall-trees, 29 shrubs, and 43 herbs for the low layer. Species richness and diversity generally increased with thinning intensities, and the trends were more evident for the low layer. Aboveground biomass significantly differed among thinning intensities for both shrubs and herbs. Also there was a negative correlation between biomass and the current number of stems per hectare. The current study suggested that the effects of thinning on light conditions at the forest floor, species richness and diversity and production of understory vegetation continued seven years after the treatment.
( Ji-young Park ),( Geun-won Jang ),( Yu-ri Heo ),( Mee-kyoung Son ) 조선대학교 구강생물학연구소 2017 Oral Biology Research (Oral Biol Res) Vol.41 No.2
CAD/CAM technology is increasingly being used for the fabrication of various prostheses. Digitized attempts are also underway for both removable partial dentures as well as fixed partial dentures. Conventional methods to fabricate removable partial denture require innumerable laboratory procedures, such as impression, surveying, blockout, making fire model, and wax-up. In this paper, we demonstrate the process using electronic surveying and blockout in Sensable`s intellifit<sup>TM</sup> Digital restoration system, and zirconia surveyed crown and framework fabrication through the digital process. The clinical application of digital systems in the dental field is expected to increase with the advancement and development of technology in the near future.
Ji, Ho-Il,Hwang, Jaeyeon,Yoon, Kyung Joong,Son, Ji-Won,Kim, Byung-Kook,Lee, Hae-Won,Lee, Jong-Ho The Royal Society of Chemistry 2013 Energy & environmental science Vol.6 No.1
<P>The chemical diffusion coefficient (<I>D</I><SUB>chem</SUB>) of epitaxial LSC thin films was measured by a newly designed conductivity relaxation method. <I>D</I><SUB>chem</SUB> of epitaxial thin films was found to be higher than that of bulk LSC by up to two orders of magnitude, and was found to be enhanced further as the film became thinner.</P> <P>Graphic Abstract</P><P>The <I>D</I><SUB>chem</SUB> of LSC films has been measured by employing a newly contrived unique method based on the conductivity relaxation technique. Remarkably, the <I>D</I><SUB>chem</SUB> of epitaxial LSC thin films was found to be higher than that of the bulk LSC by up to two orders of magnitude, and was found to be enhanced further as the film became thinner. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c2ee21647g'> </P>
( Ji Hye Ahn ),( Hyo Jin Kang ),( You Jeong Oh ),( Young Ki Son ),( Seong Eun Kim ),( Ki Hyun Kim ),( Won Suk An ) 대한내과학회 2011 대한내과학회 추계학술대회 Vol.2011 No.1
INTRODUCTION: Dietary omega-3 fatty acid (FA) has cardioprotective effect and is associated with a slower deterioration of albumin excretion. There is no report about the effect of omega-3 FA on proteinuria in patients with diabetic nephropathy who are well controlled blood pressure with angiotensin converting enzyme inhibitors (ACEI) or angiotensin II receptor blockers (ARB). We hypothesized that omega-3 FA supplementation decrease proteinuria and change erythrocyte membrane FA contents which is related with acute coronary syndrome in patients with diabetic nephropathy. METHODS: In a double-blind randomized placebo-controlled design, a total of 19 patients treated with ACEI or ARB, was randomized to treatment for 12 weeks with omega-3 FA or a control treatment. We measured proteinuria with random spot urine and urine collected for 24 hours. Urinary liver-type fatty acid binding protein (L-FABP), prostaglandin E2 (PGE2) and neutrophil gelatinase-associated lipocalin (NGAL) were measured by enzyme-linked immunoassay. Erythrocyte membrane fatty acid contents were measured by gas chromatography. RESULTS: The mean age of the enrolled patients was 60.4±10.7 years and mean blood pressure was 121/72 mmHg. Baseline urinary protein to creatinine ratio, 24 hours urine protein and serum creatinine were 0.74±0.65 g/g, 0.53±0.53 g and 1.23±0.20 mg/dL. Blood pressure, proteinuria, albuminuria (443.2±614.6 mg/g vs. 348.0±390.6 mg/g), serum creatinine, L-FABP, PGE2, NGAL (35.1±57.2 ng/mL vs. 25.4±17.8 ng/mL) and lipid profile were not significantly changed in omega-3 FA supplemented group after 12 weeks compared to baseline. The eryt! hrocyte membrane contents of eicosapentaenoic acid (EPA) (p=0.025) were significantly increased and arachidonic acid to EPA ratio (p=0.012) and oleic acid (15.8±2.9 % vs. 13.1±2.2 %, p=0.036) were significantly decreased in omega-3 FA supplemented group after 12 weeks compared to baseline. CONCLUSIONS: Although there is no additive effect of omega-3 FA on proteinuria, FA contents of erythrocyte membrane were significantly changed by omega-3 FA treatment for 12 weeks in patients with diabetic nephropathy who are well controlled blood pressure with ACEI or ARB.
Protective Effects of Manassantin A against Ethanol-Induced Gastric Injury in Rats
( Ji Won Song ),( Chang Seob Seo ),( Tae In Kim ),( Og Sung Moon ),( Young Suk Won ),( Hwa Young Son ),( Jong Keun Son ),( Hyo Jung Kwon ) 영남대학교 약품개발연구소 2016 영남대학교 약품개발연구소 연구업적집 Vol.26 No.-
Manassantin A, a neolignan isolignan from saururus chinensis, is a major phytochemical compound that has various biological activities, including anti-inflammatory, neuroleptic, and human acyl-CoA : cho-lesterol acyltransferase (ACAT) inhibitory activities. In this study, we investigated the protective effects of manassantin A against ethanol-induced acute gastric injury in rats. Gastric injury was induced by intra-gastric administration of 5mL/kg body weight of absoulye ethanol to each rat. The positive control group and the manassantin A group were given oral doses of omeprazole (20mg/kg) or manassantin A (15mg/kg), respectively, 1h prior to the administration of absolute ethanol. Our examinations revealed that manassantin A pretreatment reduced ethanol-induced hemorrhage, hyperemia, and epithelial cell loss in the gastric mucosa. Manassantin A pretreatment also attenuated the increased lipid peroxidation associated with ethanolinduced acute gastric lesions, increased the mucosal glutathione (GSH) content, and enhanced the activities of antioxidant enzymes. The levels of pro-inflammatory cytokines, tumor necrosis factor-α (TNF-α), interleukin (IL)-6, and IL-iβ were clearly decoreased in the manassantin A-pretreated group. In addition, manassantin A pretreatment enhanced the levels of cyclooxygenase (COX)-1, COX-2, and prostaglandin E<sub>2</sub> (PGE,) and reduced the inducible nitric oxide synthase (INOS) overproduction and nuclear factor kappa B (NF-κB) phosphorylation. Collectively, these results indicate that manassantin A protects the gastric mucosa from ethanol-induced acute gastric injury, and suggest that these protective effects might be associated with COX/PGE<sub>2</sub> stimulation, inhibition of INOS production and NF-κB activation, and improvements in the antioxidant and anti- inflammatory status.