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RISS 인기검색어
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- 저자 : Jeung-Hwan Seo (검색결과 37 건)
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서영수,김용관,신동환,공보금,이정구,박정환,윤성환,정치영,이상경,김영훈 대한생물치료정신의학회 2001 생물치료정신의학 Vol.7 No.2
Objectives : This open prospective study was performed in order to evaluate the efficacy and extrapyramidal adverse effects of nemonapride in the schizophrenic patients, and was compared wit one of typical antipshchotics. haloperidol and one of atypical antipsychotics, risperidone. Methods : Thirty male and female schizophrenic patients(DSM-Ⅳ) were treated for 12 weeks with haloperidol(n=10), risperidone(n=10) and nemonapride(n=10). The overall efficacy was assessed at baseline, 1st week, 2nd week, 4th week, 8th week, and 12th week by the Positive and Negative Syndrome Scale for Schizophrenia(PANSS). Also the overall safety was assessed in the same time period by the Extrapyramidal Symptom Rating Scale(ESRS). Results : There were no significant differences in PANSS scores(total, positive, negative, and general psychopathology subscale) among haloperidol, risperidone, and nemonapride groups, Treatment responders, defined as at least 20% reduction of baseline total PANSS score, were achieved by 8 patients(80%) in haloperidol group, 10 patients(100%) in risperidone group, and 8 patients(80%) in nemonapride group. And there were no significant differences in ESRS total scores among haloperidol, risperidone, and nemonapride group. Inter-group comparison among haloperidol, risperidone and nemonapride group, as assessed by the ESRS, revealed no significant differences in the shifts to the maximum score, 9.4(±9.4), 6.2(±8.4), and 11.3(±8.1) respectively, and also revealed no significant differences in the mean time reaching the maximum score, 4.5(±4.5) week, 7.8(±4.8) week, and 4.6(±4.4) week, respectivily. Conclusion : There wee no significant differences in the efficacy and extrapyramidal adverse effects among haloperidal, rispecridone and nemonapride groups. These results suggest that nemonapride was as efficacious and safe in he treatment of schizophrenia, as well known and widely used antipsychotics, haloperidol and risperidone.
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서정호,송현정,김대환 공주대학교 문화재보존과학연구소 2004 문화재과학기술 Vol.3 No.1
銀製葡萄獸禽文小甁 新例는 통일신라의 대표적인 문양으로 구성된 것이며, 그 제작기법이 우수하고 예술성도 뛰어나 금속세공기술 연구에 있어서 중요한 자료이다. 또한 출토사례가 많지 않아 매우 희귀한 예라고 할 수 있다. 이 병은 개인 소장품으로 출토당시부터 어깨부 한쪽이 부식되어 박락되어 있었다. 장기 보존을 위해서나 전시를 위해서는 추가 부식을 방지하기 위한 保存方案이 필요하다. 유물의 내부구조와 상태를 파악한 후에 유물이 최대한 원형을 유지할 수 있도록 적절한 처리가 이루어져야 할 것이다. The new case of Silver Bottle is composed of representative design of Unified Silla, and because the production technique is superior and the artistic as well, it is the important material for the study of metalwork technique. And it is the rare case, for there aren‘t many excavated cases. This bottle is personal possession and one side of shoulder is corroded and exfoliated at the time of excavation. For the long-term preservation or display, conservation method which prevents additional corrosion is needed. After catching the inner structure and state, proper treatment should be done in order that remains can retain its original form.
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Seo, Jongsu,Tsvetkov, Nikolai,Jeong, Seung Jin,Yoo, Yeongeun,Ji, Sanghoon,Kim, Jeong Hwan,Kang, Jeung Ku,Jung, WooChul American Chemical Society 2020 ACS APPLIED MATERIALS & INTERFACES Vol.12 No.4
<P>Solid oxide fuel cells produce electricity directly by oxidizing methane, which is the most attractive natural gas fuel, and metal nanocatalysts are a promising means of overcoming the poor catalytic activity of conventional ceramic electrodes. However, the lack of thermal and chemical stability of nanocatalysts is a major bottleneck in the effort to ensure the lifetime of metal-decorated electrodes for methane oxidation. Here, for the first time, this issue is addressed by encapsulating metal nanoparticles with gas-permeable inorganic shells. Pt particles approximately 10 nm in size are dispersed on the surface of a porous La<SUB>0.75</SUB>Sr<SUB>0.25</SUB>Cr<SUB>0.5</SUB>Mn<SUB>0.5</SUB>O<SUB>3</SUB> (LSCM) electrode via wet infiltration and are then coated with an ultrathin Al<SUB>2</SUB>O<SUB>3</SUB> layer via atomic layer deposition. The Al<SUB>2</SUB>O<SUB>3</SUB> overcoat, despite being an insulator, significantly enhances the immunity to carbon coking and provides high activity for the electrochemical oxidation of methane, thereby reducing the reaction impedance of the Pt-decorated electrode by more than 2 orders of magnitude and making the electrode activity of the Pt-decorated sample at 650 °C comparable with those reported at 800 °C for pristine LSCM electrodes. These observations provide a new perspective on strategies to lower the operation temperature, which has long been a challenge related to hydrocarbon-fueled solid oxide fuel cells.</P> [FIG OMISSION]</BR>
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서정길(Seo, Jeung-Gil),이환범(Lee, Hwan-Beom) 한국지방정부학회 2010 지방정부연구 Vol.14 No.2
세계 기후변화협약은 인간 활동 결과에 따라 발생되는 온실가스 배출량의 최소화를 통해 지구대기의 안정성 그리고 지구 온난화 방지를 목표로 삼고 있다. 우리나라 역시 세계 기후변화협약의 실질적 구현을 위해 경제, 산업, 에너지, 환경, 기술개발, 교역 문제 등에 이르기까지 다양한 영역에서의 변화 및 쇄신이 불가피하게 되었다. 이에 국가적 차원에서 보다 거시적이고도 총체적인 정책대응 그리고 다각적이고도 구체적인 실행방안 수립이 긴요하다 할 것이다. 이러한 맥락에서 청정개발사업(CDM) 또한 중앙정부는 물론이거니와 지방정부 그리고 관련 기업 등을 중심으로 활성화 방안이 적극 모색될 필요가 있는 것이다. 본 연구는 지방정부 차원의 청정개발사업(CDM) 추진과 관련하여 대구시 방천리 매립가스 자원화 사례분석을 중심으로, 추진사업의 성과 극대화 방안을 정책.제도 관점, 지역경제 활성화 관점, 그리고 친환경관점에서 제안하고자 한다. 연구결과에 의해 도출된 성과 제고 방안들은 향후 우리나라 지방자치단체의 청정개발사업 추진 및 활성화 전략수립 등에 있어서 중요한 의미를 제공할 수 있을 것으로 사료된다. In order to participate in international efforts to prevent global warming, Korea joined the Climatic Change Convention in December 1993 and ratified the Kyoto Protocol on October 30, 2002. In Kyoto Protocol, Korea has secured the position of a developing country (Non-Annex B). Meanwhile, the clean development mechanism for reducing greenhouse gas emission is underway centering in local governments in Korea. In terms of that, Daegu Metropolitan City is promoting the project making Land fill Gas generated in Bangcheonri sanitary land fill as resources as well as linking to the clean development project. In keeping with this view, this study tries to analyze problems focusing on the cases according to promotion of Daegu Bangcheonri Land fill Gas resources project and present some alternatives to maximize the performance of the clean development project, through three perspectives such as policy and institutional support, local economy activation, and eco-friendly development plan.
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췌장의 신경내분비 종양 122예의 임상양상 및 악성 예측인자
한정혜 ( Jeung Hye Han ),김명환 ( Myung Hwan Kim ),문성훈 ( Sung Hoon Moon ),박수정 ( Soo Jung Park ),박도현 ( Do Hyun Park ),이상수 ( Sang Soo Lee ),서동완 ( Dong Wan Seo ),이성구 ( Sung Koo Lee ),김송철 ( Song Cheol Kim ),한덕종 대한소화기학회 2009 대한소화기학회지 Vol.53 No.2
목적: 췌장의 신경내분비 종양은 매우 드문 종양이나, 진행속도가 늦어 췌장선암종에 비해서는 예후가 좋다. 그러나 악성 신경내분비 종양은 양성에 비해 예후가 불량하다. 따라서 이번 연구에서 췌장의 신경내분비 종양의 임상 특징과 악성 예측인자 및 생존율에 영향을 미치는 인자에 대해 조사하였다. 대상 및 방법: 1990년 11월부터 2006년 12월까지 조직검사에서 췌장의 신경내분비 종양으로 진단받은 122명의 환자를 대상으로 하여 임상기록, 방사선 소견, 수술기록, 병리기록 등을 후향 검토하였다. 결과: 122명의 췌장 신경내분비 종양 환자 중 75명(61.5%)은 비기능 종양이었고 평균 관측기간은 45.0±38.0개월이었다. 환자의 평균 연령은 48.9±14.0세였으며, 성별에 따른 차이는 없었다. 가장 흔한 임상증상은 비기능 종양에서는 복통(44.0%), 인슐린종에서는 저혈당성 신경증상(100%), 가스트린종에서는 설사(60%)였다. 종양의 크기는 4-140 mm로 평균 29.8±23.2 mm였다. 조직학적으로는 32명(26.2%)이 악성 소견을 보였다. 일변량 분석에서는 종양의 크기가 클수록(>20 mm), 비기능성 종양일수록 악성 소견을 나타내었으나(p<0.001, p=0.002), 다변량 분석에서는 종양의 크기만이 유일한 악성 예측인자였다(p=0.001). 복부 전산화단층촬영에서 종괴 내에 석회화가 보인 환자 8명 중 5명이 악성 소견을 보여 의미가 있었다(p=0.015). 수술 절제는 114명에서 이루어졌고, 양성의 췌장신경내분비 종양 환자는 수술 후 재발 없이 모두 생존하였다. 32명의 악성 종양 환자 중 6명이 수술 후 또는 진단 후 평균 40.3개월 만에 사망하였다. 전체 환자의 질병특이 5년 생존율은 92%였고, 종양의 크기가 작을수록, 원발 병소를 수술 절제할수록, 림프절 침윤이나 원격 전이가 없을수록 생존율이 의미 있게 높았다. 결론: 췌장의 신경내분비 종양은 기능 여부와 관련 없이 크기가 클수록 악성화의 가능성이 높으며 또한 질병특이 생존율도 의미 있게 낮은 것으로 나타났다. Background/Aims: Neuroendocrine tumors (NET) of the pancreas are rare. Its prognosis is better than pancreas adenocarcinoma due to the slow growth, however, malignant NET of the pancreas are observed. The purposes of this study were to evaluate the clinical characteristics and to find the predictive factors of NET which are associated with malignancy and survival. Methods: We retrospectively evaluated the clinical outcomes of 122 patients with NET of the pancreas who were pathologically diagnosed at Asan Medical Center between 1990 and 2006. Results: Mean age of the patients was 48.9±14.0 years and there was no gender predilection. The major clinical manifestations were abdominal pain (44.0%) in non-functional tumor, neuroglycopenic symptoms (100%) in insulinoma and diarrhea (60%) in gastrinoma. Tumor size ranged from 4 to 140 mm (average 29.8±23.22). Ninety cases (73.8%) were classified as benign tumors and 32 cases (26.2%) as malignant. In multivariate analysis of clinical characteristics, large sized tumor (>20 mm, p=0.001) was confirmed as sole independent factor to predict malignant NET. Surgical resection was performed in 114 patients. All patients with benign NET are still alive without recurrence. Six out of 32 patients with malignant NET died at an average 40.3 months after diagnosis. The factors indicating favorable outcome were small size of tumors (p=0.046), resection of primary tumor (p=0.000), absence of lymph node invasion (p=0.0116) and distant metastasis (p=0.0005). Conclusions: Large NET of the pancreas, regardless of their functioning status, were more likely to be associated with malignancy and predictor of worse survival. (Korean J Gastroenterol 2009;53:98-105)
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이환우(HWAN-WOO RHEE),서정호(JEUNG-HO SEO) 한국해양공학회 2004 韓國海洋工學會誌 Vol.18 No.1
It is well known that tensile peak overloads may significantly delay subsequent constant amplitude fatigue crack growth in many materials. Since real structures are usually subjected to complex load histories, the ability to predict accurate crack growth under realistic service conditions is of major engineering interest. This paper describes experiments on fatigue crack growth in the integrally stiffened panel of 7075-T6 aluminum alloy. The effect of shape parameters and overload positions on the fatigue crack growth behavior of integrally stiffened panels are discussed. Based on the experimental results, the following conclusions have been drawn: the overall fatigue crack growth retardation resulting from single overload in the stiffened panels was generally larger in the larger thickness ratio, although the retardation trends, according to the change in overload positions, were similar to those exhibited in the non-stiffened panels.
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