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Jena Lee,Yujin Suh 한국지역사회간호학회 2023 지역사회간호학회지 Vol.34 No.4
Purpose: This cross-sectional study aimed to describe subjective health status of people with chronic kidney disease (CKD), identify factors that affect good subjective health status and investigate the relationship between good subjective health status and health-related quality of life (HRQOL) in people with CKD. Methods: This secondary analysis utilized data from the Korean National Health and Nutrition Examination Survey in 2019-2020. Participants (N=295) had an eGFR of ≤59 mL/min/1.73 ㎡. Descriptive and inferential statistics were used to analyze the data. Univariate and multivariate logistic regression analyses were performed to identify factors affecting good subjective health status and examine the association between good subjective health status and HRQOL. Results: Among all participants, 61.4% had good subjective health status, and the HRQOL index was 0.88 in people with CKD. Household income, activity limitation, stress, and the number of comorbidities in people with CKD were associated with good subjective health status. People with better subjective health status were more likely to be satisfied with self-care, usual activities, and pain/discomfort in HRQOL. Conclusion: Good subjective health status is associated with better HRQOL. Therefore, subjective health status should be assessed early, and a nursing intervention program should be developed considering factors that can improve subjective health status in people with CKD.
Self-rated health and dietary adherence in people with chronic kidney disease
Jena Lee,Min Joo Kim,Jee Yun Park,Sun Em,Jung Yeon Quon,Soo Kyung Park 한국간호과학회 2021 한국간호과학회 학술대회 Vol.2021 No.10
Aim(s): Self-rated health (SRH) was thought to be an important indicator for health-related behavior in people with chronic diseases. It also has been reported that SRH was a significant predictor for dietary adherence in people with other chronic diseases. However, little is known about SRH and its relationship to dietary adherence in people with chronic kidney disease (CKD). Thus, the purposes of this study were 1) to describe SRH, 2) identify its associated factors, and 3) investigate the relationship between the SRH and dietary adherence in people with CKD. Method(s): This was a secondary analysis of dataset from 7th Korea National Health and Nutrition Examination Survey (2016-2018). Those who had estimated glomerular filtration rate (eGFR) of <60 mL/min/1.73 m2 (N=557, mean age=71.75, eGFR=58.9, male=56.8%) were included in this study. Data for demographic and clinical characteristics, and dietary adherence were obtained by interview and physical examination. Compliance for diet therapy and daily potassium level were included to describe dietary adherence. Descriptive and inferential statistics were used to analyze the data. Result(s): 320(57.5%) participants rated their SRH as “good” or “moderate” (better SRH), whereas 237(42.5%) participants responded “poor” (worse SRH). Multivariate logistic regression showed that male participants, those who were old, had middle income level, did muscular exercise were more likely to have better SRH. Current smoker and those with anxiety/depression and multiple chronic diseases were less likely to have better SRH. Regarding relationship of SRH to dietary adherence, those with better SRH were more likely to be noncompliant to diet therapy and to take more than 2.5grams of potassium, after controlled for other covariates. Conclusion(s): Understanding of associated factors for SRH and its relationship to dietary adherence will help healthcare providers develop more effective interventions to improve SRH and its impact on dietary adherence in people with CKD.
한반도 하부 고생대 퇴적암에서의 리튬과 붕소 분리 및 동위원소 분석법 개발
정제나(Jena Jeong),이승수(Seungsoo Lee),방선화(Sunhwa Bang),허영숙(Youngsook Huh) 대한지질학회 2021 대한지질학회 학술대회 Vol.2021 No.10
리튬과 붕소 동위원소는 고기후/고환경 연구에서 활용되고 있는 비전통 안정 동위원소 지시자이다. 리튬 동위원소 비는 과거 대륙 풍화 작용의 변화를 나타내며, 붕소 동위원소 비는 과거 해양의 pH 변화를 복원하는데 이용할 수 있다. 이러한 연구들은 주로 신생대 퇴적물을 대상으로 이루어져왔으나, 최근에는 이러한 연구방법론을 중생대와 고생대, 원생대 퇴적물 분석에 적용해보는 연구들이 시도되고 있다(Pogge von Strandmann et al ., 2013; Clarkson et al ., 2015). 따라서 본 연구에서도 이러한 시도의 연장선에서 한반도 하부 고생대 퇴적암을 대상으로 리튬과 붕소 동위원소 분석법을 적용해보고자 한다. 또한 연구 과정에서 시료의 주원소 및 동위원소 분석을 위한 적절한 시료 전처리의 필요성이 제기되어 이를 개발하고 검증하는 과정을 거쳤다. 연구 대상 시료는 전처리후 화학 조성을 분석하여 변질 과정이 진행된 것으로 보이는 시료를 선별했다. 주원소 분석은 ICP-AES와 ICP-MS를 활용하였고, MC-ICP-MS를 이용해 동위원소 분석을 진행했다. 리튬의 경우, 퇴적암으로부터 과거 해수의 리튬 동위원소 비를 복원하기 위해서는 상이한 동위원소 조성을 가지는 규산염질 광물을 제외하고 당시 해수의 조성을 반영하는 탄산염질 퇴적물만을 선택적으로 용해시켜야 한다. 효과적으로 시료 용해법을 시험하기 위해 석회암 시료 분쇄물과 다양한 농도의 산(0.05–0.1 M)을 서로 다른 시간 동안(1-3 시간) 반응시킨 후 그 분석 결과를 정리했다. 이후 동위원소 분석을 위해 단일 컬럼법(Choi et al ., 2013)을 이용하였고, 탄산염질 매질로부터 리튬을 99% 이상의 회수율로 분리했다. 붕소 동위원소 실험법 개발에서는 탄산염 외 물질(insoluble residue)을 제거하기 위한 전처리와 탄산염 용해 방법을 시험하며, 매질과 실험환경에 의한 붕소 오염을 통제하는데 특히 중점을 두었다. 석회암 시료에 적용할만한 붕소 분리 컬럼법을 개발하기 위해 McCulloch et al . (2014)의 방법에서 전반적인 부피를 수정하여 재설계 및 검증과정을 거쳤다. 수정 설계된 컬럼법을 이용하여 표준 물질과 대상 시료에 대해 95-100% 수율에 해당하는 최적의 용리액 수집 구간을 확보했다.
Choi, Woong,Cho, Mi Yeon,Konar, Aniruddha,Lee, Jong Hak,Cha, Gi‐,Beom,Hong, Soon Cheol,Kim, Sangsig,Kim, Jeongyong,Jena, Debdeep,Joo, Jinsoo,Kim, Sunkook WILEY‐VCH Verlag 2012 ADVANCED MATERIALS Vol.24 No.43
<P>Sunkook Kim, Jinsoo Joo, and co‐workers demonstrate on page 5832 phototransistors based on multilayer MoS<SUB>2</SUB> crystals with a wider spectral response and higher photoresponsivity than single‐layer MoS<SUB>2</SUB> phototransistors. These multilayer MoS<SUB>2</SUB> phototransistors also exhibit high room‐temperature mobilities, near‐ideal subthreshold swings, low operating gate biases, and negligible shifts in the threshold voltages during illumination. </P>
Effectiveness of marker-assisted backcrossing breeding for biotic resistance in rice
Jung-Pil Suh,Kshirod K. Jena,Young-Chan Cho,Ji-Ung Jeung,Yong-Jae Won,Im-Soo Choi,Jeom-Ho Lee,Myeong-Ki Kim,Chung-Kon Kim 한국육종학회 2013 한국육종학회 심포지엄 Vol.2013 No.07
The transfer of a biotic resistance gene from indica rice cultivars into japonica cultivars by conventional breeding methods often difficult due to high sterility of the progenies, poor plant type, and linkage drag. Molecular markers provide opportunities to map resistance genes and accelerate the application of marker-assisted backcross(MAB) breeding through the precise transfer of target genomic regions into the recurrent parent. The basis of MAB breeding is to transfer a specific gene/allele of the donor parent into the recurrent parent genome while selecting against donor introgressions across the rest of the genome. The effectiveness of MAB breeding depends on the availability of closely linked DNA markers for the target locus, the size of the population, the number of backcrosses and the position and number of markers for background selection. We have successfully developed Bph18 version of the commercially cultivated japonica elite cultivar by using MAB and incorporating the resistance gene Bph18 that conferred enhanced resistance to BPH. MAB breeding provides a new opportunity for the selective transfer of biotic resistance genes into elite indica rice cultivars devoid of linkage drag. In additon, molecular markers precisely estimate the introgression of chromosome segments from donor parents and can speed up the recipient genome recovery via background selection.