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      • KCI등재후보

        콤바인 HST 전자제어시스템 개발

        서신원(Sin-Won Seo),허윤근(Yun-Kun Huh),이제용(Je-Yong Lee),이창규(Chang-Kyu Lee),배근수(Keun-Soo Bae) 충남대학교 농업과학연구소 2011 농업과학연구 Vol.38 No.1

        I/An electro-hydraulic transmission having advantages of convenience, safety, simple linking and high power, and an electronic control system were designed and fabricated. In this study, characteristics of the control system were investigated through outdoor tests for evaluation of installation of the system on a combine. Major findings were as followings. 1. Experiment for performance evaluation of the control system was conducted on concrete road. With steering lever in neutral position, driving HST swash plate and left/right wheel speed increased in proportion to driving lever angle. In case of steering control, steering swash plate angle changed in proportion to steering lever angle. This should cause increase in outer wheel speed, but it was observed that HST swash plate was controlled toward neutral to maintain the speed before steering. As a result, speed before steering was maintained despite the change in outer wheel speed by steering HST swash plate angle change. 2. It was observed that the HST system enabled steering with outer wheel maintained at constant speeds while inner wheel speed decreased, which was more stable than conventional mechanical links. In addition, for the selected 5 criteria, experiment showed satisfactory results and it was judged that installation on real vehicle would be feasible. 3. The control system showed response property of appropriate forward/reverse movement and lift/right steering, without causing any problems during experiment on concrete. Result of response property experiment on field operation also showed appropriate control over forward/reverse movement and left/right steering

      • KCI등재

        정부조직의 ‘조직융합관리’에 관한 시론적 연구

        임영제(Young Je Yim),이창원(Chang-Won Lee) 한국정책과학학회 2008 한국정책과학학회보 Vol.12 No.4

        1990년대 이후 주요선진국들은 정부혁신의 한 가지 방편으로 정부부처들을 통합하는 정부조직의 개편을 단행하였고, 우리나라 역대 정부들도 그동안 정권이 바뀔 때 마다 정부조직의 효율성, 생산성 제고 등의 기치 하에 부처 간 통폐합을 시도하였으나 통합의 시너지 효과를 보지 못하고 여러 가지 부작용을 경험해온 것이 현실이다. 이러한 부작용을 최소화하고 의도했던 조직통합의 효과를 얻기 위해서는 조직의 융합관리가 필요하다. 본 연구에서는 그동안 조직의 특정 변수에 치우쳐 연구되어 왔던 조직통합, 조직융합에 대한 연구를 검토함으로써 조직융합의 통합적 접근법을 시론적으로 제시하고자 하였다. 아울러 개념적 혼란이 남아 있는 것으로 생각되는 통합과 융합의 개념적 정립을 시도함으로써 이로 인한 개념상의 혼란과 융합지표 설정의 혼란 등을 해결할 수 있는 단서를 제공하고자 시도하였다. 이를 위하여 우선 조직융합에 관한 선행연구들을 조직문화적 측면, 인적자원관리적 측면, 구조기능적 측면의 세 가지 측면으로 나누어 살펴보았다. 조직융합의 개념정립과 관련해서는 통합과는 차별화되는 융합의 개념을 제시하고 이를 바탕으로 조직융합의 통합적 접근을 모색하였다. 즉 조직문화적 접근, 관리과정적 접근, 구조기능적 접근의 세 가지 접근을 통하여 ‘화학적 결합’으로서의 조직융합의 방향을 제시하였다. This study finds the successful management strategies of PMI (post-merger integration) in public organizations and explores the process of the PMI in public organizations. PMI is the most important phase of organizational change. The PMI period is very similar to any strategic change management process for an organization. It must continually assess the speed of the changes being made, establish clear leadership, communicate effectively, maintain a human resource focus throughout the process, deal with both internal and external resistance, and make rational decisions. It must be dynamic in adapting to the ever-changing circumstances. What is the message that this study leaves for practicing managers and academics? A successful strategy of PMI(post-merger integration) in the public organizations is depends on having strategy or merger logic that goes beyond simple cost saving, rationalization, and the capacity to realize those strategic benefits through the public and cultural integration processes that are the focus of this study.

      • A preliminary study in melasma following INMODE forma procedure

        ( Soon-hyo Kwon ),( Je-byeong Chae ),( Jung-won Shin ),( Jung-im Na ),( Chang-hun Huh ),( Kyoung-chan Park ) 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.2

        Background: Melasma is a common hypermelanosis that frequently appears on the face. In recent studies, it is suggested that dermal structural alteration, including solar elastosis and basement membrane disruption, may have an important role in the pathogenesis of melasma. Forma device (InMode Inc, Richmond Hill, ON, Canada, North America) is a radiofrequency dermal heating device used on facial wrinkles and rhytides. Objectives: The aim of this study was to evaluate the effects of Forma device on melasma in a small group of volunteers. Methods: All volunteers were treated 4 times at 3 weeks intervals. Every visit, melanin index and erythema index was measured to assess the improvement in hyperpigmentation and erythema. Clinical photos were evaluated to estimate the degree of skin changes. Results: Clinical and instrumental evaluation showed that melasma improved after INMODE forma treatment. Conclusion: We suggest that treatment with Forma device may have beneficial effects on melasma by dermal remodeling and direct heat delivery on melanocytes.

      • SCISCIESCOPUS

        Expression of cellular retinoic acid-binding protein-I (CRABP-I) in the cerebrospinal fluid of adult onset moyamoya disease and its association with clinical presentation and postoperative haemodynamic change

        Jeon, Jin Sue,Ahn, Jun Hyong,Moon, Youn-joo,Cho, Won-Sang,Son, Young-Je,Kim, Seung-Ki,Wang, Kyu-Chang,Bang, Jae Seung,Kang, Hyun-Seung,Kim, Jeong Eun,Oh, Chang Wan BMJ Publishing Group Ltd 2014 Journal of neurology, neurosurgery and psychiatry Vol.85 No.7

        <P><B>Objective</B></P><P>The elevation of cellular retinoic acid-binding protein-I (CRABP-I) has been suggested as a candidate in the pathogenesis of paediatric moyamoya disease (MMD). However, few studies have addressed CRABP-I in adult onset MMD. The aim of this study was to examine the expression of CRABP-I in the cerebrospinal fluid (CSF) of adult onset MMD, and to evaluate its association with clinical presentation and postoperative haemodynamic change.</P><P><B>Methods</B></P><P>This study examined the CSF from 103 patients: bilateral MMD, n=58 (56.3%); unilateral MMD, n=19 (18.4%); atherosclerotic cerebrovascular disease (ACVD), n=21 (20.4%); and control group, n=5 (4.9%). The intensity of CRABP-I was confirmed by western blotting and expressed as the median (25th–75th percentile). The differences in CRABP-I expression according to disease entity (unilateral MMD vs bilateral MMD vs ACVD), initial presenting symptoms (haemorrhage vs ischaemia) and postoperative haemodynamic change (vascular reserve in single photon emission CT and basal collateral vessels in digital subtraction angiography) were analysed.</P><P><B>Results</B></P><P>CRABP-I intensities in bilateral MMD (1.45(0.86–2.52)) were significantly higher than in unilateral MMD (0.91(0.78–1.20)) (p=0.044) or ACVD (0.85(0.66–1.11)) (p=0.004). No significant differences were noted based on the initial presenting symptoms (p=0.687). CRABP-I was not associated with improvement in vascular reserve (p=0.327), but with decrease in basal collateral vessels (p=0.023) postoperatively.</P><P><B>Conclusions</B></P><P>Higher CRABP-I in the CSF can be associated with typical bilateral MMD pathogenesis in adults. Additionally, postoperative basal collateral change may be related to the degree of CRABP-I expression.</P>

      • KCI등재

        다양한 골 이식재의 임상 효과에 대한 고찰

        이승범,연제영,채경준,정의원,김창성,이용근,조규성,채중규,김종관,최성호,Lee, Seung-Bum,Yon, Je-Young,Chae, Gyung-Joon,Jung, Ui-Won,Kim, Chang-Sung,Lee, Yong-Geun,Cho, Kyoo-Sung,Chai, Jung-Kiu,Kim, Chong-Kwan,Choi, Seong-Ho 대한치주과학회 2007 Journal of Periodontal & Implant Science Vol.37 No.4

        Purpose: Various bone graft materials are being used for periodontal tissue regeneration. Th materials are being developed continuously for ideal clinical effects. Therefore, it is necessary to identify the clinical characteristics of each bone graft material through comparing the various bone graft materials statistically and in doing so, proposing a more efficient bone graft material. In this study, the following results were attained through comparing the clinical effects among the bone graft materials, using the statistical method based on the clinical studies published at the department of periodontology of Yonsei hospital. Materials and Method: 6 selected studies of department of Periodontology at Yonsei University Hospital were based on clinical study of bone grafting in intrabony defects. It was compared the clinical parameters among the 6 clinical studies, using the statistical META analysis. Result: When comparing the probing depth reduction, there was a relatively great amount of decease when using the xenograft, Anorganic Bovine Derived Hydroxapatite Bone Matrix/Cell Binding Peptide(ABM/P-15: PepGen $P-15^{(R)}$) and the autogenous bone and absorbable membrane, d, 1-alctide/glycolide copolymer(GC: $Biomesh^{(R)}$). The allogfrafts showed a relatively low decrease in the probing depth and clinical attachment change. It also showed a slight decrease in the bone probing depth. The allografts showed various results according to different bone graft materials. When comparing the ABM/P-15 and bovine bone $powder(BBP^{(R)})$, ABM/P-15 showed a relatively high clinical attachment level and the bovine bone powder showed a relatively high clinical attachment level. The probing depth change and gingival recession change showed a lower value than the mean value between the two bone graft materials. The synthetic bone showed a relatively high decrease in clinical attachment level and periodontal probing depth change. There was a relatively larger amount of gingival recession when using Bioactive Glass(BG) but a relatively low bone regeneration effect was seen. Conclusion: Good restorative results of the periodontal tissue can be attained by applying the various bone graft materials being used today after identifying the accurate clinical effects.

      • KCI등재

        우황청심원 관련 최근 연구 동향 : 국내 논문에 대한 고찰

        이제원,백경민,백영두,임은영,장우석,전우현,정인권,Lee, Je-Won,Baek, Kyung-Min,Baek, Young-Doo,Im, Eun-Young,Chang, Woo-Seok,Cheon, Woo-Hyun,Chung, In-Kwon 대한한방내과학회 2010 大韓韓方內科學會誌 Vol.31 No.4

        Objectives : Woohwangchungsim-won has been used for acute diseases such as cerebrovascular disease (stroke), heart disease. The aim of this study was to determine the effects, significance & necessity of Woohwangchungsim-won in acute stages of these disease by reviewing Korean articles about Woohwangchungsim-won. Methods : Article searches were performed on 8 major Korean web article search engine from January 1980 to August 2010. There were no restrictions on the types of publication, including grey articles. Results : Forty-three articles were included. Twenty one were efficacy tests, thirteen were comparative efficacy tests, eight were toxicity tests, and one was new method development. Eighteen articles were multicenter studies and twenty five were single center studies. Thirty two articles were animal testing, only ten articles were clinical articles. Thirty seven articles presented the composition and quantity of Woohwangchungsim-won, but six did not. Conclusions : The results of Korean articles about Woohwangchungsim-won can not strongly support the effects, significance & necessity of Woohwangchungsim-won. More rigorous studies are required for determination of the effects of Woohwangchungsim-won.

      • The effects of the 3-OH group of kaempferol on interfollicular epidermal stem cell fate

        ( Je Byeong Chae ),( Hye-ryung Choi ),( Jung-won Shin ),( Jung-im Na ),( Chang-hun Huh ),( Kyoung-chan Park ) 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.2

        Background: Kaempferol (3,4′,5,7-tetrahydroxyflavone) is a flavonoid known to have a wide range of pharmacological activities. The 3-OH group in flavonoids has been reported to determine antioxidant activities. Objectives: We tested whether kaempferol can affect the expression of integrins and the stem cell fate of interfollicular epidermal stem cells. Methods: Skin equivalent (SE) models were constructed, and the expression levels of stem cell markers and basement membrane-related antigens were tested. The immunohistochemical staining patterns of integrins, p63, and PCNA were compared between kaempferol- and apigenin-treated SE models. RT-PCR was used to evaluate the mRNA expression of integrins. Results: Kaempferol increased the thickness of the epidermis when added to prepare SEs and the basal cells of kaempferol-treated SEs appeared more columnar. In the immunohistological study, the expression of integrins α6 and β1 and the numbers of p63- and PCNA-positive cells were higher in the kaempferol-treated model. RT-PCR analysis also confirmed that kaempferol increased the expression of integrin α6 and integrin β1. Conclusion: Our findings indicated that kaempferol can increase the proliferative potential of basal epidermal cells by modulating the basement membrane. In other words, kaempferol can affect the fate of interfollicular epidermal stem cells by increasing the expression of both integrins α6 and β1. These effects, in particular, might be ascribed to the 3-OH group of kaempferol

      • SCIESCOPUSKCI등재

        Case Reports : Vulval Metastasis from Squamous Cell Carcinoma of the Cervix Clinically Presenting as Lymphangioma Circumscriptum

        ( Won Jeong Kim ),( Hyun Je Park ),( Hoon Soo Kim ),( Su Han Kim ),( Hyun Chang Ko ),( Byung Soo Kim ),( Moon Bum Kim ) 대한피부과학회 2011 Annals of Dermatology Vol.23 No.1S

        Patients with cervical cancer may develop local recurrence or distant metastasis, and the rate of these events is increased in proportion to the clinical stage. Cutaneous metastasis of cervical cancer is very rare and only a few cases have been reported in Korean literature. It is common at the abdominal wall, vulva, and anterior chest wall and mainly presents as an asymptomatic dermal or subcutaneous nodule, ulcer or plaque. We herein report on an interesting case of vulval metastasis from squamous cell carcinoma of the cervix with an unusual clinical manifestation resembling lymphagioma circumscriptum. (Ann Dermatol 23(S1) S64~S67, 2011)

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