Factors associated with the risk of colorectal neoplasia in young adults under age 40

Ilsoo Kim,Han Hee Lee,Young Jae Ko,Ho Eun Chang,Dae Young Cheung,Bo-In Lee,Young-Seok Cho,Jin Il Kim,Myung-Gyu Choi 대한내과학회 2022 The Korean Journal of Internal Medicine Vol.37 No.5

Background/Aims: Recent epidemiologic studies have shown a continued increase in colorectal cancer incidence among younger adults. Little is known about the factors that contribute to the development of young-onset colorectal neoplasia (CRN). Methods: A cross-sectional analysis was performed for individuals younger than 40 years who underwent colonoscopy in Seoul St. Mary’s Hospital and its affiliated health screening center. High-risk CRN was defined as adenoma or sessile serrated lesion ≥ 10 mm, with three or more adenomas, villous histology, high grade dysplasia, or carcinoma. Results: Of these 13,621 included participants, 2,023 (14.9%) had one and more CRN. Young patients with CRN tended to be elderly, male, obese, smoker, having a habit of drinking, and having comorbidities such as hypertension, dyslipidemia, diabetes, and chronic kidney disease. In a multivariate analysis adjusted for age, sex, obesity, smoking status, and alcohol intake, old age (odds ratio [OR], 1.086; 95% confidence interval [CI], 1.054 to 1.119), male sex (OR, 1.748; 95% CI, 1.247 to 2.451), obesity (OR, 1.439; 95% CI, 1.133 to 1.828), and smoking (OR, 1.654; 95% CI, 1.287 to 2.127) were independent risk factors for overall CRN. Obesity and smoking as two modifiable factors increased the risk for high-risk CRN even more than for overall CRN (OR, 1.734; 95% CI, 1.168 to 2.575 and OR, 1.797; 95% CI, 1.172 to 2.753, respectively). Conclusions: Obesity and smoking were modifiable risk factors for CRN in young adults. They increased the risk for highrisk CRN even more than for overall CRN. A colonoscopy might be beneficial for young individuals with these factors.

성별 및 연령에 따른 심질환 연구

고영창,조휘열,조재홍 內務部 國立科學搜査硏究所 1996 國立 科學 搜査 硏究所 年報 Vol.28 No.-

서울 서초동 지역의 산성비에 대한 조사

고영신,최영재,최홍관 서울교육대학교 과학교육연구소 1996 科學과 數學敎育 論文集 Vol.22 No.-

인터넷비즈니스의 성공전략에 관한 연구

고재건,문영자 제주대학교 관광과경영경제연구소 2003 産經論集 Vol.18 No.-

수중불분리 콘크리트의 제강도 특성에 관한 실험적 연구

고용득,송재호,장일영,이승원 金烏工科大學校 1996 論文集 Vol.17 No.-

The purpose of this experimental study was carried out for the estimate of the properties of underwater non-segregation concrete. Properties of antiwashout underwater concrete is different from other type of concrete and the selection of cement types is greatly dependent on the structural requirement and construction location associated with control compressive strength and modulus of rupture Based on this, this study addresses the comparison of physical properties of concrete according to the use of different cement types. It is also recommended to select a proper cement type depending ton structural characteristics. Rational analytic formula for the modulus of rupture is to predicted from compressive strength of concrete cylinder.

국산 붉가시나무 탄화물 분석

이동영,고재형,신수정,김병로 충북대학교 농업과학기술연구소 2012 農業科學硏究 Vol.28 No.1

본문참고

Kainic Acid 투여에 의한 흰쥐 해마형성체에서의 c-fos 및 Enkephalin 유전자 발현에관한 연구

양재승,김현,고재필,서영석 대한해부학회 1994 Anatomy & Cell Biology Vol.27 No.3

지방과 도시인의 交通手段 利用實態 및 態度 比較硏究

고재홍,안미영,홍기원,차재호,구정숙 서울大學校 社會科學大學 心理科學硏究所 1993 心理科學 Vol.2 No.-

지방과 도시인의 도로교통 이용실태 및 태도 조사 결과를 보고하였다. 지방을 대표하는 지역으로 경상남도 거창읍을, 그리고 도시는 서울특별시 강남구 대치동을 선정하였고, 각 지역에서 800명(400 부부쌍)의 무선표본을 대상으로 질문지로 조사하였다. 조사내용을 출퇴근 길의 교통수단이용, 외출시의 교통수단이용, 자가용의 이용및 소유실태, 운전면허 소지 및 취득실태, 교통사고경험, 대중교통수단에 대한 평가 및 관련 태도 등이었다. 조사결과, 도시와 지방간의 현재의 교통수단 이용에서의 차이를 파악할 수 있었을 뿐 아니라, 후속연구에서 교통수단이용의 변화를 평가할 수 있는 기저선이 마련되었다. Two representative samples of married couples. one(n=400 couples) from Dae-Chi Dong in Seoul and another(n=400 couples) from the town of Ku-Ch'ang in South Kyung-sang Province were studied through a questionnaire. The questionnaire dealt with (1)transportation uses in commuting to work (2)transportation uses on weekends. (3)types of automobiles owned and the uses to which they are put. (4)statistics related to obtaining and possessing driver licenses. (5)experience of traffic accidents, and (6)attitudes regarding the public trasportations and policies. The study as designed to provide a baseline for future studies on the transportation statistics as well as gauging the urban-rural difference in automobile culture.

濟州産 한라봉 柑橘의 방사선 조사에 의한 貯藏性

고영환,김재하 제주대학교 방사능이용연구소 2001 연구보고 Vol.15 No.-

방사선 照射가 한라봉 감귤의 저장에 미치는 영향을 조사하였다. 한라봉 신선과일에 Cobalt 60으로 감마선을 0 kGy, 1 kGy, 2 kGy 그리고 3kGy를 각각 조사하여 실온 및 저온(6℃)에 저장하였다. 저장중의 부패율, 중량 변화, pH, 가용성고형분을 측정하였고, 부패와 관련된 미생물을 분리 동정하였다. 저온저장이 실온저장보다 부패방지와 갈변억제에 보다 더 효과적었다. 방사선을 조사하지 아니한 처리구나 1kGy 조사한 처리구에 비해서, 2 kGy이상 γ-방사선을 조사한 처리구는 부패와 갈변 정도가 심하였다. 저장 중에 감귤의 부패와 관련하여 나타나는 미생물은 대부분이 Penicillium 속이었다. 저온 저장했을 때가 실온 저장했을때보다 중량감소율이 더 낮았다. 또한 γ선을 2kGy 이상 조사했을 경우에는 상대적으로 중량감소가 크게 나타났다. 저장 중에 감귤의 pH와 당도는 저장기간이 경과함에 따라서 전반적으로 증가하는 경향이었다. 이러한 경향은 실온저장과 저온저장 그리고 방사선 조사구와 비조사구간에는 별다른 차이가 없었다. 전반적으로 γ 방사선을 2kGy 이상 조사하면, 감귤의 저장에 부정적인 효과가 나타났으며, 1 kGy 조사한 처리구와 방사선을 조사하지 아니한 대조구 간에는 유의적인 차이가 인정되지 않았다. 따라서, 감귤의 저장에는 방사선 조사선량을 1 kGy이하로 하는 것이 바람직하다. Effects of γ-ray irradiation on storage of citrus orange Halabong were investigated. γ-Ray was irradiated on fresh fruits of Halabong on the levels of 0 kGy, 1 kGy and 3 kGy using cobalt 60 as a radiation source. Irradiated fruits were stored at room or cold(6℃) temperatures for storage. During storage, changes in decay, weight , pH and soluble solids were monitored timewisely, and molds related with fruit decay were isolated and purified. Storage at cold temperature was more effective against decay and browning. The pretreated fruits with higher dose radiation than 2 kGy showed severe decay and browning. Most of the molds associated with fruit decay were Penicillium species. Weight loss during cold storage was less than that during room temperature storage. And irradiation of fruits with higher dose radiation than 2 kGy gave higher weight loss. Soluble solid content and pH of juice increased on the whole as the storage time went by. This tendency was all similar in every cases of fruit storage whether stored at room temperature or cold temperature regardless of γ-ray irradiation. In conclusion, higher dose radiation than 2 kGy resulted in negative effective on fruit storage, and no significant difference on the whole was observed between non-irradiated fruits and 1 kGy-irradiated fruits. It is highly recommended that citrus orange Halabong should be irradiated with lower dose of radiation than 1 kGy when necessary.

법랑질 접착에 대한 습윤 효과

고근호,조영곤,진철희,유상훈,김종욱,박병철,기영재,최희영,김종진 大韓齒科保存學會 2004 Restorative Dentistry & Endodontics Vol.29 No.3

This study evaluated the microleakage and interfacial gap between enamel and composite resin under the dry and wet condition of the enamel surface, V shaped class 5 cavities were prepared on the occlusal portion of extracted human molars. Samples were divided into three groups: D group (air dry for 10-15s), BD group (blot dry with moist cotton pellet), and DR group (air dry for 10-15s and rewet with Aqua-Prep F for 20s). Cavities were filled using Aelitefil composite resin after applied One-Step. Microleakage was tested by 2% methylene blue dye solution and the data were statistically analysed by Kruskal-Wallis test and Mann-Whitney test. Also Enamel-resin interface was observed under SEM. Group BD showed statistically lower microleakage than group D (p〈0.05). but there was no statistically significant difference between group BD and DR (p)0.05). At the enamel-resin interface, group D showed the gap of 2 ㎛ thickness, but group BD and DR showed close adaptation. In conclusion, the use of blot dry and rewetting agent (Aqua-Prep F) resulted in decreased microleakage and improved adhesion between enamel and resin when using One-Step.