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      • 흉부 유연성 운동이 척추측만증 환자의 폐활량과 흉곽 확장에 미치는 영향

        심재훈,오덕원,이규완 한국전문물리치료학회 2002 한국전문물리치료학회지 Vol.9 No.2

        The objectives of this study were to investigate the effects of thoracic flexibility exercise on chest function and mobility and to provide the information of physical therapy for patients with idiopathic scoliosis. Forty female subjects who were diagnosed with scoliosis participated in this study and were divided into the experimental and control groups. The experimental group consisted of 20 patients who were treated with thoracic flexibility exercise program during the admission (10 days) and one month after discharge. The control group consisted of 20 patients who were not treated with thoracic flexibility exercise program. Vital capacity was measured using a respirometer. The chest expansion were calculated using differences of chest circumference between maximum inspiration and maximum expiration measured under armpits, at the junction between the sternum and xyphoid process, and at the waist. All subjects were measured two times: before the admission and at one month after discharge. Data were compared by groups using independent t-test. Vital capacity and chest expansion values (the armpit, chest and waist values) were significantly higher for the experimental group compared to those of the control group (p<.05). The findings of this study show that thoracic flexibility exercise program can lead to an increase in vital capacity and chest expansion and has a positive effects in relieving symptoms and restoring thoracic mobility.

      • 정책 기반 QoS관리 구조

        심인보,이재오 한국기술교육대학교 2005 論文集 Vol.11 No.1

        현재 IP 네트워크는 최선형(best-effort) 서비스 모델에서 차등 서비스를 지원하는 네트워크로 옮겨가고 있다. 이러한 다양한 서비스 레벨을 지원하기 위하여 IETF(Internet Engineering Task Force)는 통합 서비스(IntServ) 구조와 차등 서비스(DiffServ) 구조를 제안하였다. 통합 서비스는 RSVP를 사용하여 각 흐름마다 보장된 서비스를 제공한다. 차등 서비스는 차등 서비스 수준을 각 트래픽 집합에 제공하는 것으로, 통합 서비스 구조의 RSVP를 사용해 각 흐름별 상태를 유지함으로 발생하는 규모성 문제를 피한다. 차등 서비스 네트워크상의 에지 라우터, 코어 라우터 그리고 서버 등을 각 장치별로 독립적으로 구성할 경우 동작의 일치성을 달성하기 힘들다. 따라서 본 논문은 정책 기반 QoS 관리 구조를 이용한 서비스 수락 제어를 제안하였다. 제안된 관리 구조는 IETF 정책 관리 구조를 사용함으로써 차등 서비스 네트워크에서의 QoS 관리 업무를 단순화 시킬 수 있다. 또한, 각각의 라우터들의 특정 PHB 값들을 다루는 방식과는 달리 사용자, 응용 서비스, 클래스 등으로 네트워크를 추상화하는 방식을 제공한다. 이러한 높은 수준의 네트워크 정책 관점은 QoS 관리를 단순화 시키는 이점을 제공한다. 더불어 차등 서비스 네트워크에서 RSVP를 구성하는 것과 유사한 메커니즘을 제공한다.

      • 란크릭 캅셀(플루옥세틴 20mg)에 대한 프로작 캅셀의 생물학적 동등성 시험

        심상범,조요나,오한석,류재환,이경태,김남재,서성훈 경희대학교 동서의학연구소 2001 東西醫學硏究所 論文集 Vol.2000 No.-

        Bioequivalence of two flouxetine capsule, ProzacR (Lilly kora Ltd.) and LanclicR (Samsung Pharm. IND. Co.), was evalated according to the guideline of KFDA. Twenty four healthy male volunteers (21-26 years old) were divided into two groups and a randomized 2×2 cross-over study was employed. After 60mg of fluoxetine was orally administered, blood was taken at 1, 2, 3, 4, 5, 6, 7, 8, 10, 12, 24, 32, 48 and 72 hours after administration and just before administration. Plasma was analyzed for fluoxetine and internal standard (clomipramine) by a sensitive and validated HPLC assay. The pharmaco kinetic parameters (AUCt, Cmax and Tmax) wre calculated and ANOVA test was used for the statistical analysis of parameters. Differences in (AUCt, Cmax and Tmax between two capsules were -0.90, 3.46 and -14.08% respectively. All powers (1-β) for AUGt, Cmax and Tmax were more than 0.9. Detectable differences (Δ) and confidence interval were all less than ±20%. All the parameters above met the criteria of KFDA for bioequivalence and indicated that LanclicR capsules are bioequivalent to ProzacR capsules.

      • KCI등재SCOPUS

        紅景天(Rhodiola sachlinensis)에서 항균성 물질의 분리 및 동정

        심창주,이규희,정재홍,이상덕,김영호,오만진 한국식품저장유통학회 ( 구 한국농산물저장유통학회 ) 2004 한국식품저장유통학회지 Vol.11 No.1

        홍경천의 천연 보존료로서의이용성을 검토하기 위하여 각종 용매로 홍경천 추출물을 제조하고 극성에 따라 순차분획, silica-gel chromatography, thin-layer chromatography, high perfomance liquid chromatography의 분리과정을 거쳐 순수 분리된 각 물질을 GC/MS(EI) spectrum, ¹H-NMR spectrum, ¹³C-NMR spectrum을 이용하여 항균물질을 동정하여 다음과 같은 결과를 얻었다. 홍경천에 대해 acetone, ethyl acetate, ethanol, methanol, chloroform, water의 각 용매로 추출한 결과 항균성분의 추출 용매로는 methanol이 가장 우수하였다. 홍경천 methanol 추출물을 n-hexane, chloroform, ethyl ether, ethyl acetate, n-butyl alcohol로 분획한 결과 ethyl acetate와 n-butyl alcohol 분획에서 우수한 항균력을 나타내었다. 홍경천 methanol 추출물은 그람양성 4균주와 그람음성 4균주에 대해 고체 배지의 경우 대체로 500 μg/mL에서 최소저해를 나타냈으며, 액체배지의 경우 100 μg/mL 내외에서 최소저해를 나타내었다.] Silica gel column chromatography에서 용매의 배율을 높여가며 용출한 결과 chloroform : methanol(8:2, v/v)의 비율에서 항균력이 가장 높게 나타났다. 분리된 항균성분을 silica-gel TLC plate에 용매의 비율을 높여가며 전개시켜 chloroform : methanol(9:1, v/v)에서 9개의 물질군을 얻을 수 있었으며, 그 중 항균력이 확인된 3개의 물질군을 HPLC와 NMR spectrum을 분석한 결과 gallic acid, (-)-epicatechin 및 kaempferol로 동정되었다. gallic acid, (-)-epicatechin 및 kaempferol의 항균물질 각각의 최소저해농도는 Staphylococcus aureus와 Listeria monocytogenes에 대해 gallic acid와 kaempferol 이 500 μg/mL, (-)-epicatechin이 100 μg/mL에서 저해를 나타내었다. The antimicrobial substances from Rhodiola sachalinensis were extracted, isolated and identified. The highest level of antimicrobial activity and its yield were obtained in methanol extract. The minimum inhibition concentrations of the methanol extract were 500 μg/mL on agar plate and 100 μg/mL in broth media for four gram positive and four gram negative microbials. The methanol extract was fractionated by n-hexane, chloroform, ethyl ether, ethyl acetate, and butanol, orderly. The separate was developed on the TLC plate with different solvent system ratio of chloroform and methanol. Nine substances were isolated from chloroform and methanol mixture(9:1, v/v). Among them, three isolates showed antimicrobial activity. Three substances separated by HPLC were identified by GC/MS(EI) spectrum and ^(1)H, ^(13)C-NMR spcetrum. They were gallic acid, (-)-epicatechin and kaempferol. The antimicrobial activites of each substances were shown gallic acid, (-)-epicatechin, kaempferol, orderly.

      • α-ZnAl₂S₄단결정의 Energy Gap의 온도 의존성에 대한 열역학적 함수 추정

        심상흥,심낙순,박종국,오재한,박광호 三陟大學校 1999 論文集 Vol.32 No.1

        In this work ? single crystals were grown by the chemical transporting reaction(CTR) method using high purity(6N) elements. The structure of grown ZnAl2S4 single crystals were cubic structure. The optical energy band gap was indirect band gap and the temperature dependence of optical energy gap was fitted well to Varshni equation. Also, the entropy, enthalpy and heat capacity were deduced from the temperature dependence of optical energy gap.

      • 외음부에 발생한 혈관근육섬유아세포종 1례

        오혜근,구자봉,김동출,심재영,박정훈,박영균,임성철 조선대학교 2003 The Medical Journal of Chosun University Vol.28 No.1

        We present a case of angiomyofibroblastoma of the vulva in a 32-year-old woman. The asymptomatic lesion measured 4×3cm and appeared as a gray-white myxoid mass on cut sections Histologically, it appeared as a relatively well-circumscribed spindle cell proliferation with alternating hypercellular and hypocellular areas and proliferation of thin-walled blood vessels. Immunohistochemically, the stromal cells expressed vimentin, CD34 and progesterone receptor, but not desmin, α-smooth muscle actin, S-100 protein and estrogen receptor. These features were similar to those of angiomyofibroblastoma as previously reported in the vulva except negativity for desmin A case of pathologically proven very rare tumor of angiomyofibroblastoma of the vulva is presented with a literature review

      • 上下肢 位置感覺에 대한 考察

        吳壽一,沈在龍,金潤來 江原大學校附設 體育科學硏究所 1990 江原大學校附設體育科學硏究所論文集 Vol.- No.15

        The results of relation and development between the position sensory of upper and lower limbs and motor skill, and what superior is between right and left limb are followings ; 1. It seen to have no relation between the position sensory and motor skill. It seems to have no meaningful difference statistically in the comparison of difference between sports group and non-sports group students, although, according to some investigators in special measurement parts and methods, sports group is superior. 2. It seems to be superior the both side limbs to any one side limb in the position sensory of upper and lower limbs.

      • KCI등재

        인삼첨가 Long Life면의 조직감과 관능적 특성

        정재홍,심창주,신영,권효진,이규희,오만진 한국식품영양학회 1999 韓國食品營養學會誌 Vol.12 No.5

        인삼이 밀가루의 아밀로그래프에 의한 호화 성질과 파리노그래프에 의한 반죽 성질에 미치는 영향을 조사하였다. 인삼첨가 LL면의 조직감과 관능적 특성에 미치는 영향을 분석하기 위하여 밀가루에 대하여 인삼을 5.0∼10% 첨가하여 LL면을 제조한 뒤 면의 조직 특성 분석 및 조리시험을 하고 관능검사를 하였다. 인삼을 첨가하면 아밀로그래프의 호화개시 온도를 3.1℃ 지연시켰으며, 최고 점도를 40B.U 감소시켰다. 파리노그래프의 흡수율은 1.2% 증가하였으며, 반죽의 안정도는 인삼의 첨가로 2.0분 길게 측정되었다. Hunter L값은 인삼 첨가량이 증가할수록 낮아졌으며, Hunter a, b값은 반대로 측정되었다. 인삼첨가 LL면의 층밀림 압출력은 첨가량의 증가에 따라 높아져 10.0%의 첨가는 대조구 18.65(㎏f)보다 2.3(㎏f) 높은 23.95(㎏f)로 측정되었으며, 경도도 대조구보다 5.4(㎏f) 높게 측정되었다. 인삼첨가 LL면의 무게 증가는 인삼의 첨가량이 증가할 때 다소 높게 나타났으나. 부피 증가는 오히려 높게 나타나 조직이 다소 치밀한 것으로 나타났다 용출량은 인삼량의 증가에 따라 약간 감소하였다. 미생물은 인삼의 첨가량이 증가할수록 줄어들어서 장기 저장이 가능하였다. 관능 검사 결과는 인삼첨가 LL면이 4.2 및 4.0으로 비교적 좋은 점수를 얻었다. 이같이 LL면 제조시 인삼 첨가량은 7.0%의 수준이 효과가 컸다. The influence of ginseng on the paste or gelatinization properties by amylograph and mixing properties by farinograph of wheat flour, and on quality properties, color, cooking quality, textural and sensory properties, and reducing microbial population of LL (Long Life) noodles was studied. The contents of ginseng used were from 5% to 10% based on flour weight. The viscosity property of wheat flour with ginseng was increased the initial pasting temperature but the amylograph peak viscosity were decreased in vice versa. The farinograph absorption, stability and breakdown were increased by ginseng. The whiteness of LL noodles manufactured with ginseng was lower than that of control. The shear extrusion force and hardness of LL noodles manufactured with ginseng were shown much higher value than those of control. At cooking quality examination of LL noodles manufactured with ginseng, weight of cooked LL noodles was decreased but volume was appeared in vice versa. Extraction amounts of LL noodles manufactured with ginseng during cooking were much smaller than those of control. Total counts of microorganism of LL noodles manufactured with ginseng were decreased during storage at 30℃. Sensory properties of cooked LL noodles which was manufactured with ginseng showed quite acceptable. Based on the cooking and sensory evaluation test, addition of 7.0% ginseng to wheat flour may be suitable for processing LL noodles.

      • 진행성 위암과 동반된 후복막 섬유화증 7예의 임상적 고찰

        장재영,천영국,최우봉,김진오,조주영,이준성,이문성,심찬섭 순천향의학연구소;Soonchunhyang Medical Research Institute 2000 Journal of Soonchunhyang Medical Science Vol.6 No.1

        Background/Aims: Retroperitoneal fibrosis is a fibrosing disease process which frequently develops ureteral obstruction. Malignant retroperitoneal fibrosis has been reported that various types of cancer including cancer of the breast, stomach, prostate, lung, cervix, uteri, colon, pancreas, ovary, and even Hodgkin's disease. While the pathogenesis remains obscure, small foci of metastatic neoplasm in the retroperitoneal space can elicit a desmoplastic reaction in secondary form to malignancy. Methods: Recently we experienced 7 cases of retroperitoneal fibrosis with advanced gastric cancer. So, we report 7 cases of retroperitoneal fibrosis with clinical and radiologic characteristics. Results: The most common signs and symptoms were related irreversible renal dysfunction. The urologic finding noted medial deviation of the involved ureters and hydronephrosis Conclusions: Clinical manifestations are abdominal pain, back pain, hydronephrosis, and uremia. When sudden back pain and hydronephrosis develop in advanced malignancy, physicians should be considerd for retroperitoneal fibrosis.

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