젊은 남성에서 성정체성에 대한 고환의 영향 : 지역 기반 조사 Community-Based Survey

구자현,김민의,이남규,박영호 순천향의학연구소 2002 Journal of Soonchunhyang Medical Science Vol.8 No.2

We investigated the influence of testis on the gender identity in late adolescent Korean males dwelling in a community. Of 27,202 men aged 20 years dwelling in the community, 2,700 men were randomly selected at a 10.0% sampling fraction. A total of 2,080 men who agreed to participate in the study and all volunteers underwent a standard evaluation. For the evaluation of influences of testis on the gender identity, we used the Bem Sex Role Inventory in the subjects who had testis torsion, testis injury of cryptorchidism as well as with no testicular disease. They were categorized as group 1; normal testis size, group 2; testis atrophy, and group 3; no testis in the scrotum. The median masculinity scores of group 1, 2 and 3 were not significantly different (group 1; 4.3 [3.65.0], group 2; 3.9 [3.1-4.5] and group 3; 4.6 [4.0-5.1], p=0.065). Regarding the femininity score, there were no differences among groups (group 1; 4.6 [4.0-5.1] versus group 2; 4.5 [3.9-4.8] and group 3; 4.6 [4.2-4.9], p=0.609). In group 3, the masculinity and femininity scores were not also different between of men underwent orchiectomy and did not undergo correction of cryptorchidism. We did not find the impact of testis on gender identity in our cohort. Additional research is needed to clarify the underlying psychopathology involved.

포인세티아로부터의 dihydroflavonal-4-reductase(DFR) 유전자의 분리 및 분석 : Euphorbia pulcherrima

구자정,박영두 경희대학교 생명자원과학연구원 2004 硏究論文集 Vol.23 No.-

본 연구는 포인세티아 포염색을 결정하는 화색관련유전자 dihydroflavonal-4-reductase(DFR)을 분리하고 그 기능을 분석하기 위해 수행되었다. DFR specific primer를 제작하여 RT-PCR을 통해 498 bp의 단편을 얻었으며 염기서열 분석을 통해 Gerbera hybrid와 98%의 상동성을 갖는 DFR 유전자임을 확인하였다. 기능 분석을 위하여 분리된 DFR 유전자를 CxVMV promoter에 의해 조절되는 식물 발현 벡터 Agrobacterium을 이용하여 담배(Nicotiana tobaccum cv. Havana SR1)에 형질전환하였다. 형질 전환 식물체는 잎 절편체를 재조합 벡터를 포함한 A. nanefaciens LBA440에 접종한 후 1, 2차 배지에서 신초 및 뿌리를 유도함으로서 확보할수 있었다. 1차 PCR에 의해 marker 유전자의 전이가 확인된 개체는 온실에서 재배하여 자가수분 및 채종을 하였으며 genomic DNA를 추출하여 DFR 유전자가 담배 genome 내로 전이되었음을 PCR로 다시 확인하였다. 채종된 종자는 후대 유전 분석을 위해 kanamycin이 첨가된 파종배지에서 선발중에 있다. DFR specific primer was designed to isolate dihydroflavonal-4-reductase (DFR) from Euphorbia pulcherrima cv. Feedom Red. The DFR gene fragment was isolated through RT-PCR with a set of primers designed based on homologous coding region present in DFR genes from divergent sources. To analyze the function of DFR gene, an antisense-orineted DFR gene fragment amplified by RT-PCR was cloned into a binary vector PILTAB 357 for plant transformation. This construct was introduced into Agrobacterium tumefaciens strain LBA4404 and used for transformation into the Nicotiana tabaccum cv. Havana SRI. The transformation of the antisense-orineted DFR gene into tobacco was confirmed by PCR.

하부요로증상의 회색지대에서 전립선 폐색 예측을 위한 잔뇨분수의 가치

구자현,이남규,박영호 순천향의학연구소 2000 Journal of Soonchunhyang Medical Science Vol.6 No.2

We determined whether residual fraction might be able to differentiate obstructive from no obstructive voiding dysfunction in gray zone of lower urinary tract symptom. A total of 47 patients (mean age plus or minus standard deviation 64.4 ± 7.1) with maximum flow rates between 10 and 15 ml. per second were received transurethral resection of the prostate and the duration of follow-up was ranged from 2 to 20 months (mean plus or minus standard deviation 9.7 ± 5.1). Uroflowmetry and post-void residual were measured before transurethral resection of the prostate during 2 studies. Residual fraction was defined as post-void residual divided by pre-micturition bladder volume multiplied by 100 and pre-micturition bladder volume was calculated by voided volume plus post-void residual. There was a significant correlation between the difference of pre-micturition bladder volume and that of post-void residual estimated during the first and second session (r = 0.736, p <0.001) and the intra-patient variation in residual fraction had significantly less than that in measurement of post-void residual (p <0.001). Residual fractions measured during the first and second session at baseline was inversely correlated with the increase in maximum flow rate, respectively (r = -0.401, p = 0.005, for the first session and r = -0.694, p <0.001, for the second session). Residual fraction can predict obstructive and no obstructive voiding dysfunction. Furthermore, It is simpler and less invasive than pressure-flow study and more reproducible than post-void residual measurement.

무증상의 현미경적 혈뇨의 비뇨기과적 고찰

구자현,서병욱,김영호,송윤섭,전윤수,김민의,이남규,박영호 순천향의학연구소 1998 Journal of Soonchunhyang Medical Science Vol.4 No.2

We intended to know whether all of the patients with asymptomatic microscopic hematuria should be urologically investigated routinely. We reviewed the medical records with asmptomatic microscopic hematuria from January 1995 to December 1997. Urological studies included intravenous urography or ultrasonography, urine cytology, cystoscopy and biopsy, urine AFB smear and culture and urine PCR for AFB. The age with patients ranged from 9 to 74 years(mean age: 39.7 years). Benign diseases were found in elderly patients and patients with high degree of hematuria, but there was no patients who had urological malignant disease. According to the results, we suggest that follow-up with urine cytology is sufficient to younger patients or low degree of hematuria with asymptomatic microscopic hematuria.

ADH와 Morphine 및 Alcohol의 同時投與가 흰쥐 肝組織內 Cytochrome P-450 b_5, p-nitroanisole-O-demethylation 및 AAF hydroxylation에 미치는 影響

洪永淑,金龜子,成樂應 梨花女子大學校 韓國生活科學硏究院 1985 韓國生活科學硏究院 論叢 Vol.35 No.-

Chronic morphine administration to adult male rats has long been known to change hepatic cytochrome P-450 content and its dependent mixed function oxidase activity. More recently, acute treatment of mature male rats with a dose of morphine higher than that used chronically also has been reported to change their hepatic cytochrome P-450 In the present study, the effect of morphine and alcohol by concomitant administration of ADH on the cytochrome P-450, b_5, p-nitroanisole-O-demethylation and AAF-hydroxylation in rat liver microsomes were studied. The results are as follows; 1. The contensts of cytochrome P-450, and b_5 were increased in the liver microsomes from morphine and ADH-treated rats, whereas they were decreased in liver microsome from alcohol and ADH-treated rats. 2. After administration of morphine and ADH rats, activity p-nitroanisole-O-demethylase, mixed function oxidase system were increased, whereas they were decreased after administration of alcohol and ADH rats. 3. After administration of morphine and ADH rats, the formation of lipid peroxides were decreased, whereas they were increased after administration of alcohol and ADH rats. No correlation was found between lipid peroxidation and formation of lipid peroxidases, which were induced by morphine and ADH cytochrome P-450 content. There might be another enzyme catalyzing lipid peroxidation other than cytochrome P-450. 4. The administration of morphine and ADH increased AAF-ring-hydroxylation, compared to ADH group.

국내 다층지반의 지반물성치 및 토압에 관한 고찰

구자갑,김운학,최정호,유영화,정양규 한경대학교 2004 論文集 Vol.26 No.1

This paper study on soil properties and earth pressure at the domestic multi layer. Reliable predictions of the movement of earth retaining structures and the ground adjacent to the braced walls in urban excavation are often difficult due to many variable factors. Also, Unpredictable behavior of ground and retaining structure due to variation of the above factors may cause considerable damage to the adjacent structures, and cost many of human lives as a results of retaining wall failure. The earth pressure at the retaining walls was measured at total 13 numbers sites and Peck's empirical earth pressures adapted at the design stage. The geotechnical properties by this research was proposed as a preliminary design guide line in urban excavation where controling ground movement and safety assurance of adjacent structure. The earth pressure of rock masses were found to be 70.14% of Peck's earth pressure and the earth pressure of soil were found to be 44.4% of Peck's earth pressure. It is indicated that the design earth pressures of a retaining wall is

PISA 2012 결과에 나타난 성별에 따른 학업성취 영향요인 비교

송미영,임현정,임해미,박혜영,구자옥 이화여자대학교 교육과학연구소 2015 교육과학연구 Vol.46 No.4

The existence of gender gaps in the Programme for International Student Assessment (PISA) scores has been documented in the literature. In particular, it was revealed that on average Korean female students underperform/outperform their male counterparts in mathematics/reading scores for PISA 2012. This study was conducted to examine crucial determinants in understanding gender differences. We examined whether or not the influence of educational contextual variables on mathematics, reading and science achievement differs by gender using multilevel model with each group of male and female students. As a result, there were variables that had more influence on male or female students, though there were some differences by subject. It can be concluded that females have been affected more by teachers than by parents, while males have been affected more by parents. Also, creative extracurricular activities had much more of an effect male students than females. In addition, participation in math-related activities only influenced females, and academic and vocational expectation in math and class management of math teachers only influenced male students. Based on the results, we proposed an educational and political plan that may bridge disparity gaps in academic achievement by gender.

揷木用土로서의 연탄재 利用에 關한 硏究(第2報) : Chrysanthemum morifolium의 揷穗의 發根에 미치는 揷木用土 및 粒子크기의 影響 Influence of Briquet Ash on the Rooting of Stemcuttings in Chrysanthemum morifolium

徐榮敎,具滋聲 충남대학교 농업과학연구소 1976 農業技術硏究報告 Vol.3 No.1

The purpose of this study was to evaluate the value of briquet ash as a component of rooting media in Chrysanthemum morifolium. Various rooting media were made in mixture at different ratio and alone using sand, vermiculite and briquet ash as components of soil mixture. In order to investigate the effect of the particle size of briquet ash on rooting of stemcuttings, various particle sizes were used as rooting media. Rooting ratio, number of root and root length were examined to evaluate the effect of the various rooting media and the particle sizes of briquet ash. The important conclusions of this study are summerized as follows; 1. Briquet ash was better rooting medium than sand, but it showed more effective result when it was used in mixture with other rooting media. 2. The particle size of briquet ash as a rooting medium to produce a healthy vegetatively propagated plant showed the best result at 2-3mm.

여성 하부요관석환자에서 무마취하 요관경하 배석술

박영호,송윤섭,임용순,김영호,이남규,구자현,서병욱,김민의,전윤수 순천향의학연구소 1999 Journal of Soonchunhyang Medical Science Vol.5 No.2

Although ureteroscopy(URS) has been used widely to remove ureteral calculi, there is an argument against the belief that anesthesia or admission is needed for URS. We evaluated the experience of URS without anesthesia in female patients. From September 1997 to July 1998, URS was performed in 31 female patients without anesthesia. EHL(Electrohydraulic Lithotripsy) was used in 21 patients with impacted or large stone over 5mm. All patients were given oral antibiotics for 3 days and follow-up KUB was taken to confirm successful removal of the stone one week after the procedure. Successful treatment was defined as complete removal of the stone or residual fragments less than 2mm. Overall success rate was 96.7%(30 cases among 31 cases). All but one patient tolerated with analgesia through the entire procedures. There were only minimal complications such as mild flank pain and hematuria. So, we recommend that non-anesthetic ureteroscopic removal of stone as the first choice for treatment of lower ureteral stones in female based on the minimal morbidity, high success rate and low cost.

발기부전 검사에서 천연색 복합초음파촬영술과 야간음경발기검사의 일치도

송윤섭,구자현,김민의,이혜경,김두상,박영호,이남규 순천향의학연구소 1999 Journal of Soonchunhyang Medical Science Vol.5 No.1

We intended to know that the result of color duplex ultrasonography corresponded to that nocturnal penile tumescence rigidity in the diagnosis of erctile dysfunction. We performed both color duplex ultrasonography and nocturnal penile tumescence rigidity in 15 erectile dysfunction men. Colr duplex ultrasonography was done with a 7 MHz. color Doppler unit after intracorporeal pharmacological injection and measured maximal arterail diameter, peak systolic velocity, end-diastolic velocity and the results were compared with rigidity and tumescence in nocturnal penile tumescence rigidity using RigiScan. The positive predictive value, negative predictive value, sensitivity, specificity, overall accuracy of color duplex ultrasonography was reasonable when the result of color duplex ultrasonography was compared with the that of nocturnal penile tumescence rigidity. According to this results, color duplex ultrasonography could not only predict but also correspond to nocturnal penile tumescence. Therefore, we suggest that color duplex ultrasonography can relpace nocturnal penile tumescence rigidity if psychogenic and neurogenic erectile dysfunction are distinguished by history and neurologic examination.