한약수치에 관한 연구(제 9보) : 炒甘草 제법의 표준화 및 규격화(1) Preparing Standardization and Regulation of Stir-Frying Glycyrrhzia root(1)

최혁재,이우정,박성환,송보완,김동현,김남재 EAST-WEST MEDICAL RESEARCH INSTITUTE KYUNG HEE UNI 2005 東西醫學硏究所 論文集 Vol.2005 No.-

In this study, We carried out the preparing standardization and regulation of processed Glycyrrhizae Radix(PGR) which have been widely used in oriental medicines. Glycyrrhizae Radix(GR) have been generally prepared by the stir-frying, or mix-frying with honey for purpose of decreasing sweetness and augmenting vitality. Firstly, we tried to standardize PGR prepared by the stir-frying. We purchased 14 kinds of PGR and non-processed GR(NPGR) at oriental physician's offices and oriental pharmacies on a nation scale, respectively. The amounts of dry on loss, water extract, diluted ethanol extract, ether extract, total ash, acid insoluble ash, glycyrrhizin(GL), glycyrrhetic acid(GA) and liquiritin(LQ) of them were examined. The amounts of dray on loss, GL and LQ in commercial PGRs showed remarkable decrease, while GA showed increase as compared with NPGR. In order to standardize preparing method of PGR, the effect of heating time on physico-chemical parameters and biological activities were examined. Physico-chemical parameters such as dry on loss, extract amount, GL and LQ contents in PGRs showed decrease, however, GA was increased with heating time as compared with NPGR. Also, GA obtained form heat-treated GR, was found as an artifact in PGRs. PGR was more effective than NPGR in vitro test of DPPH scavenging effect and TBA-Rs reducing effect. PGR and NPGR showed potent hepatoprotective effect on CCl_(1)-intoxicated rats. Especially, PGR prepared by 80 min of heating was the most effective. Considering these results, the optimal condition for PGR preparation was 150℃ for 80min.

한약수치에 관한 연구(제 8보) : 오수유 탕포법 The Changes of Physico-chemical Parameter and Biological Activities by Processing of Evodia Fruit

박성환,이우정,최혁재,송보완,김동현,김남재 EAST-WEST MEDICAL RESEARCH INSTITUTE KYUNG HEE UNI 2005 東西醫學硏究所 論文集 Vol.2005 No.-

We have studied the physico-chemical change and pharmacological transformation of traditional herbal medicines with processing. Evodia fruit (EF) has processed for the purpose of detoxification and reduction of its bitter taste. There are various methods of processing EF in Oriental medicinal references. Among them, we processed EF according to the method of Sang-han theory, the most famous medicinal reference. We processed EF with washing in hot water, and then dried. Processed EFs(PEFs) were prepared according to the above procedure through repetition of 1,3,5 and 7 times respectively. The contents of weight loss, water extract, diluted ethanol extract, ether extract, total ash, acid insoluble ash, alkaloids and limonin in non-processed EF (NPEF) and PEFs were examined. The weight loss, and contents of water extract and dilute ethanol extract in PEF showed decrease in proportion to increase of washing time, while the contents of ether extract, total ash and acid insoluble ash showed little change as compared with those of NPEF. And the content of evodiamine and rutaecarpine was not changed distinctly. However, the content of limonin decreased in the final processed material in proportion to increase of washing times with hot water. And the intense of bitter taste in PEF was also reduced. These results were ascribed to the flowing-out of the water-soluble portion. The biological activities of NPEF and PEF were also investigated. In the test of DPPH scavenging effect, xanthine oxidase inhibition effect and TBA-Rs effect, PEF was more effective than NPEF in vitro. Also, both NPEF and PEF showed potent analgesic and anti-inflammatory effects against in mice. Especially, PEF by 3 times washing with hot water was more effective than other PEFs. From these results, it is considered that PEF should be prepared by 3 times washing with hot water.

진균성 부비동염의 임상적 고찰

이승원,김장욱,박영진,송태현,이병돈,장혁순 순천향의학연구소;Soonchunhyang Medical Research Institute 2000 Journal of Soonchunhyang Medical Science Vol.6 No.1

The fungal sinusitis is relatively rare and mainly develops in immunocompromised hosts, but is sporadically appears in the immunocompetent patients, where its incidence tends to be increasing. Because the clinical features of this disease are similar to those of chronic suppurative sinusitis, this entity may be overlooked. We analysed thirteen fungal sinusitis from January 1997 through December 1999 based on clinical features, laboratory characteristics and operative findings. The results are as follows. 1)Fungal sinusitis occurred 3.3 times as frequently in female patients as in male patients and the peak age groups are 4th and 5th decades. 2) The time intervals between the onset of symptoms and the first hospital visit were as follows: 5 cases within 3 months, 1 case between 4 and 6 months, 3 cases between 7 and 12 months, and 4 cases over 1 year. 3) The chief complaints were nasal obstruction, postnasal drip, rhinorrhea, cheek pain, headache, ocular pain, sneezing. 4) The characteristic computerized tomographic findings were hyperattenuated lesions in the maxillary sinus and in the nasal cavity near the natural ostium. 5) The most common pathogen was Aspergillus(92.3%) 6) We performed Caldwell-Luc's operation only in 4 cases, Caldwell-Luc's operation with intranasal ethmoidectomy in 3 cases, Caldwell-Luc's operation with endoscopic sinus surgery in 3 cases and endoscopic sinus sugery only in 3 cases. 7) Most of the gross specimens revealed a fungus ball containing a black-brown necrotic debris or caseous material.

만성 화농성 중이염의 세균학적 고찰

조남순,이영훈,강기훈,최제환,송태현,이병돈,장혁순,강주원,김연준 순천향의학연구소;Soonchunhyang Medical Research Institute 2000 Journal of Soonchunhyang Medical Science Vol.6 No.1

Background and Objectives : Chronic suppurative otitis media is one of the frequent diseases in otolaryngologic field. It is important to choose of antibiotics in the management of infectious disease. But the organisms in infections have been changed and resistance to antibiotics has been grown as the development of antibiotics has been achieved. And so it has been necessary to recognize the changes of organisms and resistance in antibiotics. Our study was performed to identify the pathogens isolated from discharges in chronic otitis media and evaluate the antibiotic agents, to recognize the change of to resistance to·antibiotic agents and to use the appropriate anitiotics. Materials and Methods : Retrospectively, authors reviewed the backeriologic study of 114 cases of chronic suppurative otitis media who visited the Department of Otolaryngology, Soonchunhyang University in Seoul from Nov. 1996 to Oct. 1999 and analyzed 101 strains and its sensitivity test to various antibiotics. Result : In 93 cases in which pathogenic organism was isolated, single infection was 85 cases(91.4%) and mixed infection was 8 cases(8.6%). The most frequent pathogenic organism was Staphylococcus aureus(59.4%), Pseudomonas aeruginosa(13.9%), Providencia(4.8%), Alcaligenes(3.0%) and Streptococcus pneumoniae(2.9%) were the next. Methicilline-Resistance Staphylococcus aureus was 34 cases(57.6%) of Staphylococcus aureus. Staphylococcus aureus was sensitive to Vancomycin(96.7%), Trimethoprim-Sulfamethoxazole (57.6%), Cefuroxime(42.4%) and Ciprofloxacin(40.7%) but resistant to Penicillin(94.9%). Pseudomonas aeruginosa was sentitive Amikacin(100%), Ciprofloxacin(100%) and Gentamicin(67%). Conclusion : As MRSA recently was wide spread in community accquired infection as well as nosocomial infection, we must consider strict control of MRSA.

Effect of hydraulic pressure on alumina coating on pore characteristics of flat-sheet ceramic membrane

Song, In-Hyuck,Bae, Byung-Seo,Ha, Jang-Hoon,Lee, Jongman Elsevier 2017 CERAMICS INTERNATIONAL Vol.43 No.13

<P><B>Abstract</B></P> <P>Porous ceramic membranes have been widely studied recently owing to their outstanding thermal and chemical stability. In this paper, we investigate the preparation of an alumina coating over a diatomite-kaolin composite support layer in order to reliably tailor the porous coating structure and avoid defects, such as cracks. In particular, the effect of hydraulic pressure on the alumina coating was investigated using a flat-sheet membrane support. A flat-sheet diatomite-kaolin composite support filter was manufactured by an extrusion process. The characteristics of the membrane pores in an alumina coating on the diatomite-kaolin composite support layer were studied using scanning with electron microscopy, mercury porosimetry, and capillary flow porometer.</P>

Effects of silicon particle size on microstructure and permeability of silicon-bonded SiC ceramics

SONG, In-Hyuck,HA, Jang-Hoon,PARK, Mi-Jung,KIM, Hai-Doo,KIM, Young-Wook Ceramic Society of Japan 2012 JOURNAL OF THE CERAMIC SOCIETY OF JAPAN - Vol.120 No.1405

Oblique aerial image matching based on iterative simulation and homography evaluation

Song, Woo-Hyuck,Jung, Hong-Gyu,Gwak, In-Youb,Lee, Seong-Whan Elsevier 2019 Pattern recognition Vol.87 No.-

<P><B>Abstract</B></P> <P>This paper presents a fast and accurate method for matching oblique aerial image pairs. In order to achieve accurate matching results, we must consider viewpoint differences between the input images in addition to rotation and scaling. Existing methods that match aerial image pairs with viewpoint differences undergo heavy computation and have difficulty finding correspondences. In this paper, we propose a homography matrix evaluation method based on a geometric approach to increase the accuracy of image matching results. In addition, we achieve faster matching through an iterative transform simulation that reduces computational complexity. Experimental results show that the proposed method improves aerial image matching in terms of computational efficiency while achieving successful matching results.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Iterative transform simulation is proposed to reduce the computational complexity of image matching. </LI> <LI> A geometric method to evaluate the homography matrix is proposed to filter out wrong matching results. </LI> <LI> Superior performance in terms of speed while maintaining accuracy in matching oblique aerial images. </LI> </UL> </P>

The Value Relevance of Non-financial Measure

Song, Hyuck Jun 덕성여자대학교 사회과학연구소 2004 사회과학연구 Vol.10 No.-

본 연구는 고객만족도와 같은 비재무적 측정치와 재무적 성과사이의 관련성에 관한 분석을 수행하였다. 비재무적 측정치로는 고객만족지수를 사용하였고 재무적 측정치로는 기업의 시장가치와 주가를 이용하여 가치관련성을 분석하였다. 올슨모형(1995)모형과 횡단면적 가치평가모형을 사용하여 분석한 결과 고객만족지수는 유의적인 가치관련성을 갖는 것으로 확인되었다. 특히 고객만족지수의 점수 보다는 고객만족지수의 순위가 보다 높은 가치관련성을 보였다. 또한 고객만족지수는 추가적인 정보로서 가치를 지니는 것으로 확인되었다.

Effects of Mg Suppressor Layer on the InZnSnO Thin-Film Transistors

Song, Chang-Woo,Kim, Kyung-Hyun,Yang, Ji-Woong,Kim, Dae-Hwan,Choi, Yong-Jin,Hong, Chan-Hwa,Shin, Jae-Heon,Kwon, Hyuck-In,Song, Sang-Hun,Cheong, Woo-Seok The Institute of Electronics and Information Engin 2016 Journal of semiconductor technology and science Vol.16 No.2

We investigate the effects of magnesium (Mg) suppressor layer on the electrical performances and stabilities of amorphous indium-zinc-tin-oxide (a-ITZO) thin-film transistors (TFTs). Compared to the ITZO TFT without a Mg suppressor layer, the ITZO:Mg TFT exhibits slightly smaller field-effect mobility and much reduced subthreshold slope. The ITZO:Mg TFT shows improved electrical stabilities compared to the ITZO TFT under both positive-bias and negative-bias-illumination stresses. From the X-ray photoelectron spectroscopy O1s spectra with fitted curves for ITZO and ITZO:Mg films, we observe that Mg doping contributes to an enhancement of the oxygen bond without oxygen vacancy and a reduction of the oxygen bonds with oxygen vacancies. This result shows that the Mg can be an effective suppressor in a-ITZO TFTs.

Colloidal Crystal Templating of Two-Dimensional Ordered Macroporous SiCN Ceramics

Song, In Hyuck,Kim, Yong Jin,Kim, Hai Doo,Kim, Dong Pyo Trans Tech Publications, Ltd. 2008 Diffusion and defect data. SSP. [Pt. B], Solid sta Vol.135 No.-

<P>In this study, two-dimensional (2D) ordered macroporous SiCN ceramics were prepared by infiltrating sacrificial colloidal silica (SiO2) templates with the low molecular weight preceramic polymer, polysilazane. This was followed by a thermal curing step, pyrolysis at 1250°C in a N2 atmosphere, and finally the removal of the templates by etching with diluted HF. In particular, 100large-scale monolayer silica crystals were prepared on the cleaned Si substrates by spin coating. Two-dimensional SiCN ordered pore arrays were fabricated by a solution-dipping template strategy.</P>