Optimizing the Hospital Blood Bank Stock in Korea: A Comparative Analysis of the Uniform 5-Day Stock Index and a Novel Blood Stock Index

Park Seo-Jin,Lim Young Ae,Kim Kyung-Hee 대한진단검사의학회 2024 Annals of Laboratory Medicine Vol.44 No.3

Background: Maintaining optimal blood inventory levels in hospitals is important to prevent blood shortage and wastage. We aimed to provide an efficient blood inventory management strategy for hospital blood banks nation-wide by comparing the current use of 5-day issuable stock (IS) with Lim’s IS as a novel target IS. Methods: The average and CV of daily usage (DU) were calculated from information entered into Korea’s Blood Management System by 194 participating hospitals in 2019 and 2020. Using these data, Lim’s IS was calculated by determining the simulated annual average blood shortage day nearest to 1 for each blood group in each hospital. The 5-day IS (5IS) was estimated by multiplying the average DU in 2018 by five to count the shortage days in 2019. Results: The average DU (0.3–231.3 units) and corresponding CV (0.33–7.14) in the participating hospitals were inversely proportional (r=–0.699 to –0.695). The hypothetical averages of 5IS and Lim’s IS were 27.0±41.2 and 24.7±20.8, respectively (P=0.006). The shortage days for 5IS and Lim’s IS were 8.9±22.7 and 1.0±1.9, respectively (P<0.001). Conclusions: While 5IS was unacceptable for universal application, Lim’s IS remained near one shortage day and is considered more efficient than 5IS. Hospitals should implement indicators that consider DU and its variations. This is the first study to introduce Lim’s IS as an indicator of optimal blood inventory, and the data are expected to provide guidance for effective blood inventory management nationwide, particularly during blood shortages.

Biofilter Modeling for Waste Air Treatment : Comparisons of Inherent Characteristics of Biofilter Models

Lim, Kwang-Hee,Lee, Eun Ju 한국화학공학회 2003 Korean Journal of Chemical Engineering Vol.20 No.2

The types of biofilter modeling may be primarily classified in accordance with whethef a biofilm is differentiated from other phases in each model. It may be a secondary classification with regard to biofilter-modeling whether sorption volume and / or adsorption are adopted as reservoirs or not. Thirdly, biofilter models are classified as to whether adsorption is assumed to exist through gas phase and / or a biofilm. Among all the biofilter-models of previous investigators all model-components including gas phase, a biofilm, sorption volume and adsorption surface are considered only in the model of Lim. Since his model does not require a numerical solution to describe the concentration of organic pollutants in waste-ari-streams along the height of a biofilter even under unsteady-state conditions, it satisfies the condition of simplicity that is one of the important model requirements. In spite of its simplicity, Lim's model predictions are fairly good to fit Hodge and Devinny's experimental data.

Physiochemical Characteristics of Lim’s Valley Potatoes in Korea

Hee-Don Choi,Hae-Chang Lee,Sung-Soo Kim,Yun-Sook Kim,Hak-Tae Lim,Gi-Hhyung Ryu 한국원예학회 2008 한국원예학회 기타간행물 Vol.- No.-

중국여대생의 체형연구 Ⅰ

孫喜順,林珣,金孝淑,孫希定,장희경,鄭嶸 服飾文化學會 1999 服飾文化硏究 Vol.7 No.3

This research analyzes characterization and classification of body types for the Chinese women with body measurement values. The measurement has gauged in 1999 in Beijing Institute of Clothing Technology in China. 100 women of the Chinese college women aged 17 and 24 in China were mwasured for this research. In the results of frequency analysis, the tall of Chinese women were 158.37㎝ and also has less than 150㎝ high, and has thick under bust circumference, and has a group of more than 18㎝ for width of nipple to nipple. In the results of factor analysis. Factor 1 represented the degree of abesity, while factor 2 indicated the stature and the arm length. The body types are classified into five types by cluster analysis. The stature and weight varied according to types, leading to a classification focusing on the body size determined by stature and weight factors.

흰쥐 Kupffer 세포에 대한 Propofol의 작용

박세훈,지대림,성언기,김희선,송인환,박희영,김준수,이덕희,박대팔 대한마취과학회 2002 Korean Journal of Anesthesiology Vol.43 No.4

Background: Propofol has an antioxidant capacity and can be used for ischemia-reperfusion injury of the liver. However, the effects of propofol on the Kupffer cells have not been establisked. Methods: Kupffer cells were isolated and cultured from male Sprague-Dawley rats. The effects of propofol on the Kupffer cells were evaluated by a phagocytosis assay, TNF-α gene expression, and superoxide anion release after administering propofol in different concentrations on the cultured Kuprrer cells. Results: The latex bead phagocytosis by the Kupffer cells was suppressed when the Kupffer cells were exposed to propofol irrespective of concentrations. Higher propofol concentrations decreased the loss of Kupffer cells after latex bead phagocytosis. Propofol induced TNF-α mRNA expression in the Kupffer cells, but the mRNA expression level after 50㎍/ml of propofol decreased. The pattern of TNF-α mRNA expression induced by propofol was different to that induced by LPS: TNF-α mRNA was expressed continuously in the propofol-treated cells until 16 hours after exposure to propofol, whereas the level of TNF-α mRNA expression induced by LPS was evident after 2 hours and was not found thereafter. TNF-α production after propofol treatment was not higher than that of the control. Formazan presipitation did not show any qualitative differences between cells untreated or treated with propofol concentrations of 0.5, 5.0, and 50 ㎍/ml. Conclusions: These results showed that propofol might inhibit Kupffer cells. This suggests that propofol and be used for patients with ischemia-reperfusion injury of the liver. (Korean J Anesthesiol 2002; 43: 475~484)

Biofilter modeling integrated with Lim’s adsorption model

Eun Ju LEE,Wui Sook JEON,Hye Min YOON,Hye Jin SONG,Byeung Soo KIM,Hee Jeong KIM,Eun Jeong OH,Kwang-Hee LIM 한국생물공학회 2011 한국생물공학회 학술대회 Vol.2011 No.10

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

일반 피부관리실과 프랜차이즈 피부관리실의 고객 이용만족도와 선택기준

임희야,김원중 인제대학교 2008 仁濟論叢 Vol.23 No.1

The main objective of this paper is to examine customer satisfaction and selection criteria of general and franchise skin care shops and to analyze them from the marketing perspective, so that the results can be utilized in establishing management strategies of this health business. Based on this objective, an interview survey was conducted through structured questionnaire for the customers of several skin care shops located in Busan-Kyongnam area during the period of 3/1-3/30/2007, and data from 481 respondents were utilized in the final analysis. Survey items included general characteristics of the customers(age, marital status, income, etc), their skin care utilization statistics, and various factors of customer satisfaction and skin care shop selection criteria based on marketing 4P(product, price, place, promotion). SPSS(version 10.0) was used to process the data. Major findings are as follows : 1) General characteristics of the respondents showed that age of 25-30, high school graduates and unmarried persons were most frequent. As for the household monthly income, the group of '2-3 million Won' was most frequent. 2) In terms of marketing mix(4P), the most important selection criterion for skin care shop appeared to be quality, followed by price, promotion and access(convenience). 3) Regarding the comparison of the customer satisfaction between general and franchise skin care shops, 'effect of care', 'unique techniques of the shop', 'respect for the customer's opinion' and 'accurate assessment of the skin condition' were more evaluated for the general shops, while 'interior facilities' and 'convenience in accessibility' were more evaluated for the franchise shops. 4) Regression analysis showed that, for the general shops, household monthly income was found to be the significant factor affecting the satisfaction level, whereas for the franchise shops, age, marital status and skin health condition were the significant factors. 5) These results imply that the successful marketing strategy for the franchise skin care shops should target 'young wives' with emphasis on 'new trend' interior facilities and convenience in accessibility.

젖산의 농도와 pH가 인공 치근 우식 병소의 형성에 미치는 영향

임유경,허복,이희주 大韓齒科保存學會 1997 Restorative Dentistry & Endodontics Vol.22 No.2

The purpose of this study was to evaluate the effect of concentration and pH of lactic acid on the formation of artificial root caries lesions formation in bovine teeth. The characterictics of artificially produced early root lesions were observed with polarized light microscope and the depth of lesions were mearsured with measuring microscope The results were as follows: 1. In the group of low pH and high concentration of lactic acid, the progress of lesion formation was faster than that of high pH and low concentration lactic acid group. 2. In the same group, initial lesion progress faster, but progression rate was reduced as time goes by. 3. In the development of initial root caries, cementum was act as a barrier to protect dentin from lesion progression.

조택원의 예술세계에 나타난 민족적 성향에 관한 연구

임희영 이화여자대학교 체육대학 보건체육연구소 2001 이화체육논집 Vol.5 No.-

With Ishihi-baku's Shinmuyong (new dance) performances in 1926 as the starting point, dance, on this land, which had been looked down upon as being vulgar due to feudalistic and confucianistc ideologies, gets established and recognized as one field of art. Differently from prior laying of importance on dance itself, shinmuyong gets settled down as a dance, on stage, of which the creativity and the artisticality of the creator are regarded as important. Cho, Taek-won, together with Choi, Seung-hee, became a pupli of Ishihi-baku(Seok, Jeong-mak), and accelerated the settling down of shinmuyong in Korea. He is one of the figures who made shinmuyong a model of Korean modern dance. This thesis intends to double the value endowment regarding the ethnic group inclination as they appeared in Cho, Tark-won's art view and works of art. It has as its objective the illumination of Cho, Taek-won's existence and the ethnic meaning. Under the conditions of activity in which they could not but be passive and general due to Japan, in the situation of the time in whoch it was the forcible rule by the Japanese Empire, he had been engaged in lively activities in the aspect of the independent standing of dances. As such as the theoretical background, by taking a look at the society, cultural situation, traditions, and the concept of ethnicality of the time, Cho, Taek-won's activities and art view in mordern dance and ethnic inclinations as they appear in the representative works of art are reasoned out. Regardless of the results influenced by shinmuyong, as an art which is essentially creation-centered, in the aspect that the right to freedom regarding the system of values and the judgments of the creating person are possessed, and by illuminating the ethnic inclinations of Cho, Taek-won, dances, as artistic activities, this thesis hoped to be utilized as a basis for presenting the future direction of dances, as artistic activities that achieve harmonious balances of historical participation and cultural creations.