상수도관의 노후도에 대한 환경영향인자의 상관성 분석

정원식,이현동,김이태,유명진 대한상하수도학회 2003 상하수도학회지 Vol.17 No.2

This study is performed to evaluate the correlation of environmental factors for drinking water pipe deterioration using statistical analysis such as multiple regression, cluster analysis, discriminant analysis, and the adequacy and dependability of grouping factors used to deterioration prediction model. Results of this study are presented that high correlation related to pipe deterioration is showed not laying year of pipe but characteristic of surrounding area and analysis of chemical components. Therefore, major influence factors of pipe deterioration for types of cast iron pipe are product quality of pipe, environmental factors using pipe deterioration evaluation model is classified to 4 types such as group related to pipe body and to hydraulic & water quality, and to characteristics of surrounding area, and to trouble & discontent of customer. And the very high adequacy of group classification is represented that the applied grouping items in this study are agree to previous studies.

안면부, 유방 및 상완부에 발생한 홍반성 루푸스 지방층염 1예

송유근,손두식,명형준,이현정,임중규,김순호,김윤아 朝鮮大學校 附設 醫學硏究所 2004 The Medical Journal of Chosun University Vol.29 No.2

Lupus erythematous panniculitis is a chronic inflammatory disease of subcutaneous fat that occurs in 2-3% of patients with systemic lupus erythematosus. Lupus erythematous panniculitis typically presents with firm, indurated subcutaneous nodules or plaques commonly developed in proximal extremities, trunks, head and neck. Face, breast and upper extremities involvement with lupus erythematous panniculitis has been infrequently reported. We report a case of lupus erythematous panniculitis developed in a 27-year-old female confirmed by histologic features and laboratory findings.

탄소섬유 프리프레그 외부 표면 적층방법에 따른 하이브리드 샤프트 진동특성

홍동표,김현식,홍용,고유곤,유청환 한국공작기계학회 2009 한국공작기계학회 춘계학술대회논문집 Vol.2009 No.-

Studies on carbon fiber epoxy composite is being conducted broadly in industries because of its specific stiffness, specific strength and good fatigue resistance. Because carbon fiber epoxy composite has high vibration characteristics, if existing metal material is alternated by carbon fiber epoxy composite, structure will be low weight, satisfy 1st bending natural frequency and have high fatigue resistance. In this study, research on to manufacture hybrid propeller-shaft using carbon fiber epoxy composite instead of current steel propeller shaft of rear wheel drive vehicle. For this, change of 1st bending natural frequency by the number of layers of carbon fiber epoxy composite on the outer surface of aluminum shaft was observed. Compared the change of 1st bending natural frequency by FEA with computer simulation and vibration test. Through this, the amount of increase in 1st bending natural frequency of hybrid shaft by the increase in number of layers of carbon fiber epoxy composite and high vibration characteristics of hybrid shaft was acknowledged.

데스크탑 마이크로 성형시스템의 가진성형에 따른 동특성 연구

홍동표,고유곤,홍용,김현식,이재완 한국공작기계학회 2009 한국공작기계학회 춘계학술대회논문집 Vol.2009 No.-

In this study, a desktop forming system which enables hydro dynamic bearing forming was developed. It consists of power train system, frequency forming system, manufactured Die-set, and controller of desktop forming system. The desktop micro forming system is focused on a higher load capacity and a shorter forming time than conventional system. Therefore it was designed for power train capability and load condition of Ball Screw. Moreover, a Piezo actuator was installed to make accurate machining possible, however, the Piezo actuator generate noise and vibration. Thus we performed the analysis of dynamic characteristics through the experiment about developed system in order to reduce such problems and discuss the alternative methods.

마이크로 프레스 구동을 위한 기어시스템 개발

홍용,김현식,고유곤,홍동표,김성욱 한국공작기계학회 2008 한국공작기계학회 춘계학술대회논문집 Vol.2008 No.-

In this paper, gear system for Micro-press actuator parts is developed. The micro-press system consists of AC geared servo motor, gear system and high precision ball screw. Herein, the micro-press gear system not only forms the micro thin foil valve but also forms the hydro dynamic bearing for a high precision rotational equipment, we analyzed the transmitted power capacity of gear system and torque, angular velocity of ball screw, because we are to select the appropriate servo motor and then we apply result of analysis to the micro press system. For the next step, we plan to study for the development of forming speed for a productivity with high precision.

마이크로 프레스 구동을 위한 기어시스템 개발

홍용,김현식,고유곤,홍동표,김성욱 한국공작기계학회 2008 한국공작기계학회 추계학술대회논문집 Vol.2008 No.-

In this paper, gear system for Micro-press actuator parts is developed. The micro-press system consists of AC geared servo motor, gear system and high precision ball screw. Herein, the micro-press gear system not only forms the micro thin foil valve but also forms the hydro dynamic bearing for a high precision rotational equipment. we analyzed the transmitted power capacity of gear system and torque, angular velocity of ball screw, because we are to select the appropriate servo motor and then we apply result of analysis to the micro press system. For the next step, we plan to study for the development of forming speed for a productivity with high precision.

동종 조혈모세포이식 후 발생한 치명적 홍역 폐렴 1예

백창렬,이동건,최정현,정현화,조유경,박훈준,이승훈,박윤희,이교영,민우성,김춘추,신완식 대한감염학회 2001 감염 Vol.33 No.4

As a result of the enlarging pool of unvaccinated children and young adults, there has been an increase in measles in our countries. In these situation, it has been reported that measles associated pneumoinia is easily complicated with fatal respiratory failure, espycially in immunocompromised patients. Herein we report the case of lethal measles pneumonia after allogenic hematopoietic stem cell transplantation in adults proven by autopsy. Recently, one case of measles was encountered in 39-year-old female patients after allogenic bone marrow transplanted case (chronic myelogenous leukemia), who progressed into interstitial pneumonia pattern, despite treatment including antibiotics, immunoglobulin. The patient died of giant cell pneumonia compatible with that of measles which was comfirmed in the section of necropsy lung specimen. (Korean J Infect Dis 33:301∼309, 2001)

Gullian Barre Syndrome 患者 1例에 대한 症例報告

임승민,안정조,최영,조현경,김민상,유병찬,오병렬,김윤식,설인찬 대전대학교 한방병원 2002 惠和醫學 Vol.11 No.1

Gullian Barre Syndrome is an acute symmetric polyradiculoneuropathy that typically presents as a progressive flaccid paralysis. The pathology is believed to be caused by both cellular and humoral immune processes The possibility of death is 3-5% and About 20% of patients require mechanical ventilaton. Recently We have experienced a patient who had suspected Gullian Barre Syndrome for 60days, his condition weakness and pain was impoved through the herb and acupucture Therefore I reported it for the treatment.

기술교과 교육 제도 및 연구의 국제적 동향 : ICTES '95 발표 논문을 중심으로 through Analyzing of Papers Presented at the ICTES '95

이재원,김진순,류창렬,노태천,최완식,최유현,송일민 충남대학교 공업교육연구소 1995 論文集 Vol.18 No.1

The purposes of this study were: (a) to analyze the papers presented at the ICTES according to the papers' representing countries and their main subjects, (b) to analyze the educational systems of the countries in technology education, and (c) to review the international trends of technology education through the papers presented at the conference. The papers(64 total) presented at the ICTES could be classified into eight countries of papers representing Japan(37), Taiwan(8), Korea(6), U. S. A.(3), India(3), Philippines(3), China(2), Singapore(2). The main subjects the papers dealt with could also be classified into educational system/history(9). curriculum/objectives and contents(9), international activities(9), methods/teaching-learning process and teaching materials and new media(40). Followings were the major and new issues presented at the ICTES: (a) Introduction of each country's technology education system. (b) Proposition of a new framework for technology education and a world core curriculum in technology education. (c) Creativity and problem-solving for the instructional method of technology education. (d) Methods and utilization of high technology media in technology education. (e) Necessity of engineering concept in technology education in technology oriented society. (f) Proposition of philosophical direction of technology education based on famous Asian philosophers.

Bioactivity-guided isolation of ginsenosides from Korean Red Ginseng with cytotoxic activity against human lung adenocarcinoma cells

Yu, Jae Sik,Roh, Hyun-Soo,Baek, Kwan-Hyuck,Lee, Seul,Kim, Sil,So, Hae Min,Moon, Eunjung,Pang, Changhyun,Jang, Tae Su,Kim, Ki Hyun The Korean Society of Ginseng 2018 Journal of Ginseng Research Vol.42 No.4

Background: Lung cancer is the leading cause of cancer-related death worldwide. In this study, we used a bioactivity-guided isolation technique to identify constituents of Korean Red Ginseng (KRG) with antiproliferative activity against human lung adenocarcinoma cells. Methods: Bioactivity-guided fractionation and preparative/semipreparative HPLC purification were used with LC/MS analysis to separate the bioactive constituents. Cell viability and apoptosis in human lung cancer cell lines (A549, H1264, H1299, and Calu-6) after treatment with KRG extract fractions and constituents thereof were assessed using the water-soluble tetrazolium salt (WST-1) assay and terminal deoxyribonucleotidyl transferase-mediated dUTP nick end labeling (TUNEL) staining, respectively. Caspase activation was assessed by detecting its surrogate marker, cleaved poly adenosine diphosphate (ADP-ribose) polymerase, using an immunoblot assay. The expression and subcellular localization of apoptosis-inducing factor were assessed using immunoblotting and immunofluorescence, respectively. Results and conclusion: Bioactivity-guided fractionation of the KRG extract revealed that its ethyl acetate-soluble fraction exerts significant cytotoxic activity against all human lung cancer cell lines tested by inducing apoptosis. Chemical investigation of the ethyl acetatesoluble fraction led to the isolation of six ginsenosides, including ginsenoside Rb1 (1), ginsenoside Rb2 (2), ginsenoside Rc (3), ginsenoside Rd (4), ginsenoside Rg1 (5), and ginsenoside Rg3 (6). Among the isolated ginsenosides, ginsenoside Rg3 exhibited the most cytotoxic activity against all human lung cancer cell lines examined, with $IC_{50}$ values ranging from $161.1{\mu}M$ to $264.6{\mu}M$. The cytotoxicity of ginsenoside Rg3 was found to be mediated by induction of apoptosis in a caspase-independent manner. These findings provide experimental evidence for a novel biological activity of ginsenoside Rg3 against human lung cancer cells.