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      • KCI등재후보

        원주 법천리출토 금동식리에 대한 연구

        권혁남,유혜선 국립중앙박물관 2001 박물관보존과학 Vol.3 No.-

        Scientific analysis are carried on gilded ornamental shoes, which have been excavated from tomb No 1. and No 4. in Beopcheon-ri, Wonju dated from Baekje Period. This object is a very important because it provides valuable information on the development of metal-making techniques of that period. Thus, this article illustrates the investigation conducted to reveal how the object was created using what materials and techniques. Instead of the spikes-attached to the bottom plate of the object-that couldn't be sampled, a sample of a decorative rivet showing a similar structure to the spikes-attached to the other parts of the shoes-was prepared for a cross-section examination. Using radiography and microscopes, it was found that the head of a spike was placed and then punched to the gilded plate, so it can be held to the shoes. Under the SEM-EDS, the cross-section of the rivet shows that the gilding layer was applied before the attachment of the rivets. It also shows that the gilding layer is distributed unevenly and there are empty spaces indicating amalgam gilding was employed. This was confirmed as Mercury was detected on the SEM-EDS analysis of the object. The examination of the microstructure of the plate using the SEM-EDS revealed that the object is made of a single copper alloy plate with recrystallized twining and non metallic white inclusions, which found to be lead in this case. 백제 문화의 중요한 자료가 되고 있는 원주 법천리 고분군 중 1호분과 4호분에서 금동식리편이 발굴되었다. 특히 이 식리에는 스파이크가 존재하여 백제의 식리 제작과 금동 기술에 대한 정보를 제공할 수 있다. 본 연구는 이곳에서 출토된 식리편을 분석하여 식리의 제작 방법, 당시 사용된 동의 특성 등을 조사하였다. 스파이크는 투과X-선과 현미경 등을 통해 관찰해 본 결과 하나의 몸체로 제작되어 머리 부분을 두드려 금동판에 부착하였다. 이 금동판은 대부분 구리로 되어 있으며 재결정에 의한 쌍정이 나타나고 있고, 비금속 개재물의 EDS 분석 결과 납을 함유하고 있다. 또한 금동판이 두 개로 되어있다는 증거가 나타나지 않아 장식용으로 리벳을 사용한 것으로 보인다. 금동판의 도금은 금도금층의 두께가 불균일하고 내부가 비어 있으며 EDS 분석에서 수은이 검출되는 것으로 보아 아말감법에 의한 도금을 하였다.

      • 괴사성 장염 환아의 금식기간 결정을 위한 Iohexol의 유용성 : Iohexol의 위장과 투여 후 채취한 소변을 전산화단층촬영법을 이용

        정유진,홍성완,류민현,정철주,문경래 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.3

        Background: Necrotizing enterocolitis is the most common gastrointestinal emergency in the neonates and its course is often fulminating with progressive lethargy. The purpose of this study is to determine the period of NP0(non per os) treatment in the patients with neonatal necrotizing enterocolitis. Matenal and methods: For determining the normal range of CT(Computerized tomography) attenuation coefficients of urine from normal neonates, 60 normal neonates participated in this study. And urine specimens from 16 patients with stage IIB necrotizing enerocolitis were obtained 8-12 hours after the instillation of iohexol enterally. The attenuation coefficients of each urine specimen were determined with CT. Periodic examinations were performed at an interval of two days. As soon as the values of attenuation coefficients reached the normal range, we discontinued NPO treatment. Results: The mean period of NPO treatment of 16 patients with stage IIB necrotizing enterocolitis was 11.1 days. The NPO period of 6 patients were 8 days, two were 10 days, four were 12 days, one was 14 days and three were 16 days. Conclusion: By means of this study, we were able to determine the period of NPO treatment on a case by case basis. The authors think that CT examination of the obtained urine after the instillation of iohexol may be a good method to determine the period of NPO treatment.

      • KCI등재

        입원된 정신활성물질 남용자의 사회정신의학적 특징

        이혁,김유광,김경빈 大韓神經精神醫學會 1991 신경정신의학 Vol.30 No.1

        This study was attempted to clarify sociopsychiatric characteristics according to the class of psychoactive substances which were classified into 8 groups such and methamphetamin, cocaine, inhalants(bond/gas), dextromethorphan(Romilar), sedatives marijuana, analgesics and etc. The data of the study were collected from 134 psychoactive substance abusers(89men, 45women), who had admitted to SNMH during past 5 years. The results were as follows ; 1) The mean age of patients was 26.5±9.6 years and according to the class of psychoactive substance, inhalant and dextromethorphan abusers were significantly younger than sedatives and analgesics abusers(P〈0.01). 2) 43.1% of patients were grown up in broken family until puberty and 27.9% of married patients showed unstable marital state such as a divorce or seperation. 3) 41.4% of patients had past history of delinquent behavior and especially, inhalants and dextromethorphan abusers had more past history of delinquent behavior than sedatives and analgesics abusers(P〈0.01). 4) The main motive of mitiation of psychoactive substance was peer pressure, relief of psysical symptoms, curiosity in that order. 75% of inhalants abusers were itiated by peer pressure, but most of sedatives and analygesics abusers used it for the purpose of relieving of physical symptoms, and methamphetamine abusers used it mainly due to peer pressure or for the purpose of increasing sexual plesure(P〈0.01). 5) 57.5% of patients reported the experience of unwanted response such as unpleasant hallucinatory state, loss of control, and psychotic state after use of psychoactive substances. Especially the unwanted respose was reported more frequently in methamphetamin and inhalants abusers. 6) 38.5% of patients abused more than two classes of psychoactive substances, and their significant combination types were not found but inhalant-dextromethorphan, analygesics-sedatives and methamphetamine-marijuana combination types were relatively common.

      • Spheroid 조합자극치료 적용이 신체구성에 미치는 영향

        홍성찬,김영빈,정동혁,박병근,김유성,이성진 원광대학교 체력과학연구소 2008 體力科學硏究 Vol.30 No.1

        The present study aims to explore the effects of applying spheroid-combined stimulating therapy on body composition. For this aim. 20 persons were selected as subjects and 10 of them each were assigned to the experimental group and control group, respectively. The experimental group was applied a 12-week combined stimulating therapy and changes in physical constitution of the members were measured before application and 4, 8 and 12 weeks after application. From the study, following conclusions could be drawn: First, body weights of the experimental group decreased from 59.9kgs before application of the spheroid-combined stimulating therapy to 57.2kgs 12 weeks after application, no significant but 4.51% change. Second, body fats of the experimental group changed from 18.8kgs before application to 16.4kgs 12 weeks after application, no significant but 12.77% reduction. Third, % fats of the experimental group decreased from 31.2% before application to 28.6% 12 weeks after application, no significant change but 8.33% reduction. Fourth, body mass index(BMI) of the experimental group decreased from 23.23 kg/㎡ before application of the therapy to 21.43kg/㎡ after application, no significant but 8.03% reduction. As seen above, the 12-week application of the spheroid-combined stimulating therapy produced no significant changes in physical constitution as physical exercise did, but improved physical constitution by reducing certain amount of boy weight, body fat, % fat and BMI. In order to detect more positive and significant changes in physical constitutions, continued studies and clinical experiments should be performed to more diverse subjects using technically reinforced equipment for spheroid-combined stimulating therapy.

      • English Paper Presentation 6: Radiology/Procedures/Education/Administration/Q.I : OE6-7 : The Effectiveness of A Newly Developed Reduction Method of Anterior Shoulder Dislocations; The Sool`s Method

        ( Hyuk Sool Kwon ),( Kyu Seok Kim ),( Tae Yun Kim ),( You Hwan Jo ),( Jin Hee Lee ),( Jae Hyuk Lee ),( Yu Jin Kim ),( Joon Hee Kim ) 대한응급의학회 2014 대한응급의학회 학술대회초록집 Vol.2014 No.2

        The objective of this study was to demonstrate the effectiveness of the Sool`s method of anterior shoulder dislocations. This was a retrospective study conducted in a university affiliated emergency department (ED). Sequence of the Sool`s method: (1) the patient is placed in a sitting position. (2) The patient to raise the affected arm and hand with forward flexion until the angle of the arm and trunk reaches 90 degree, and put the patient`s hand on the operator`s shoulder of same side. (3) The operator grabs the muscles of anterior part of deltoid and pectoralis of affected side with a hand of the patient`s hand putted on and grabs the elbow of affected side with an opposite hand and pulls the elbow slowly with slight lateral rotating and massages the muscles of anterior part of deltoid and pectoralis. 59 eligible patients presented to the ED were recruited. 35 patients were recruited to TSRT and 24 patients were recruited to the Sool`s method. The rate of successful reduction in ED was 80% (26/35) in TSRT group and 75% (18/24) in the Sool`s method group (P=0.75). The length of (LOS) in the ED was 72.3 minutes in the Sool`s method group and 98.4 minutes TSRT group (P=0.037). No significant difference in neurovascular deficit before and after reduction between both groups was reported. In the Sool`s method group, procedural time of successfully reduced cases was shorter than failed cases (P=0.015). The Sool`s method was as successful as other methods in reducing shoulder dislocations. Sool`s method has shown encouraging results including significant reduction in LOS in ED, and unnecessary use of sedation. Sool`s method is technically easy and requires only a chair or a bed to sit on and a single operator, which reduces the use of valuable ED resources.

      • KCI등재

        Heterotrimeric G protein signaling and RGSs in Aspergillus nidulans

        Yu Jae-Hyuk The Microbiological Society of Korea 2006 The journal of microbiology Vol.44 No.2

        Heterotrimeric G proteins (G proteins) are conserved in all eukaryotes and are crucial components sensing and relaying external cues into the cells to elicit appropriate physiological and biochemical responses. Basic units of the heterotrimeric G protein signaling system include a G protein-coupled receptor (GPCR), a G protein composed of ${\alpha},\;{\beta},\;and\;{\gamma}$ subunits, and variety of effectors. Sequential sensitization and activation of these G protein elements translates external signals into gene expression changes, resulting in appropriate cellular behaviors. Regulators of G protein signaling (RGSs) constitute a crucial element of appropriate control of the intensity and duration of G protein signaling. For the past decade, G protein signaling and its regulation have been intensively studied in a number of model and/or pathogenic fungi and outcomes of the studies provided better understanding on the upstream regulation of vegetative growth, mating, development, virulence/pathogenicity establishment, and biosynthesis of secondary metabolites in fungi. This review focuses on the characteristics of the basic upstream G protein components and RGS proteins, and their roles controlling various aspects of biological processes in the model filamentous ascomycete fungus Aspergillus nidulans. In particular, their functions in controlling hyphal proliferation, asexual spore formation, sexual fruiting, and the mycotoxin sterigmatocystin production are discussed.

      • Validation and Application of a Qualitative Real-Time Polymerase Chain Reaction Method for Detecting Genetically Modified Papaya line 55-1 in Papaya Products

        Yu Jihn Kwon,So Young Chung,Eun Joo Koo,Ji Eun Park,Dong Hyuk Seo,Yo A Lee,Yu Young Jung,Hee Eun Min,Mi Ran Kim,Eungui Kang,Jeongyun Cho,Seong Soo Park,Sun Ok Choi,Chul Joo Lim 한국육종학회 2014 한국육종학회 심포지엄 Vol.2014 No.07

        Genetically modified (GM) papaya (Carica papaya L.) line 55-1 (55-1), which is resistant to papaya ringspot virus infection, has been marketed internationally. Many countries such as the European Union, Japan, and Korea have a mandatory safety assessment, approval and labeling regulations for GM foods. Thus, there is a need for specific methods for detecting 55-1. In this study, we established a real-time PCR detection method applicable to 55-1 for a variety of papaya products. The limit of detection was possible for fresh papaya fruit up to dilutions of 0.005% and 0.01% (weight per weight [w/w]) for homozygous SunUp and heterozygous Rainbow cultivars, respectively, in non-GM papaya. The 55-1 event-specific detection method observed parallelism (r2>0.99) between the concentration of line 55-1 cultivars and Ct values obtained in amplification plots at concentrations of 0.005-10% for SunUp DNA and 0.01-10% for Rainbow DNA. The method was applicable to the qualitative detection in various types of processed products (cocktail fruit, dried fruit, juice, etc.) containing papaya as a main ingredient. Monitoring papaya products for the presence of GM papaya were demonstrated using a P35S and T-nos real-time PCR detection method but no amplification signals were detected.

      • Effects of extrusion speed on the microstructure and mechanical properties of ZK60 alloys with and without 1wt% cerium addition

        Yu, H.,Hyuk Park, S.,Sun You, B.,Min Kim, Y.,Shun Yu, H.,Soo Park, S. Elsevier Sequoia 2013 Materials science & engineering. properties, micro Vol.583 No.-

        The effects of extrusion speed on the microstructure and tensile properties of the ZK60 and ZK60-1Ce alloys were investigated by performing indirect extrusion at three ram speeds (0.3, 1.0 and 3.0mm/s). All of the extruded alloys showed a bimodal microstructure consisting of equiaxed fine recrystallized (DRXed) grains and elongated coarse unDRXed grains. With increasing extrusion speed, the exit temperature increased due to deformation heating, resulting in a larger grain and a higher DRXed fraction. The yield and ultimate tensile strengths and elongation at RT decreased with an increase of extrusion speed. The ZK60-1Ce alloys exhibited a finer grain size, a higher DRXed fraction, and weaker texture intensity than the ZK60 alloys at the same extrusion speed due to the inhibition of grain growth by the pinning effect and the promotion of DRX by particle-stimulated nucleation. The yield and ultimate tensile strengths at room and elevated temperatures were increased by the addition of Ce, while elongation was decreased due to cracking at the Mg-Zn-Ce particles.

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