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Vortex-Induced Vibration Optimization of a Wide Streamline Box Girder by Wind Tunnel Test
Ming Li,Yanguo Sun,Hongmiao Jing,Mingshui Li 대한토목학회 2018 KSCE JOURNAL OF CIVIL ENGINEERING Vol.22 No.12
Although the streamline box girder exhibits an excellent aerodynamic performance, they are often suffer severe Vortex-Induced Vibrations (VIVs) due to complicated separation and reattachment of air flows. It is necessary to apply control measures on the streamline box girder to suppress VIV. In this study, the VIV optimizations of a super wide streamline box girder were conducted via a series of section model wind tunnel tests. The effects of wind fairings, inspection vehicle rails, guide vanes, traffic barriers and handrails on the heaving VIV performance of the wide streamline box girder were analyzed. The test results show that the inspection vehicle rail and handrail are the main members to induce the heaving VIV of the box girder. A sharper wind fairing without changing the distance of railings is favorable to the heaving VIV performance. However, the countermeasures of changing the position of inspection vehicle rail and installing guide vanes under the girder have slight influences on reducing heaving VIV responses. Inspired by the spanwise sinusoidal perturbation method, the traffic barriers sealed with plates by regular intervals along the bridge deck can suppress the heaving VIV of the box girder successfully. The porosity of handrails has a significant effect on the heaving VIV. By using a sharp wind fairing and circular simplified handrails, the VIV performance of the wide streamline box girder was greatly improved. Their mitigation abilities were verified by a large-scale section model wind tunnel test.
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Ling‑Hong Miao,Wen‑Jing Pan,Yan Lin,Bo Liu,Ming‑Chun Ren,Qun‑Lan Zhou,Xian‑Ping Ge 한국유전학회 2017 Genes & Genomics Vol.39 No.12
The objective of this study was to analyze the target genes and regulatory function of miR-34a in Megalobrama amblycephala using second-generation highthroughput sequencing and bioinformatic tools. Functional enrichment analysis was performed by gene ontology. MiR- 34a and target gene expression levels were measured in M. amblycephala fed normal and high-carbohydrate diets. The results revealed that miR-34a was highly conserved in several species, and miR-34a of M. amblycephala has a close evolutionary relationship to that of zebrafish and common carp. miRanda, TargetScan, RNAhybrid predicted 5,185, 6,282 and 2,168 target genes, respectively, and 645 target genes were in common. According to annotation information, the target genes were enriched in phosphate metabolism, glycerophospholipid metabolism, Golgi vesicle transport, cell division, and other biological processes (P < 0.05). Pathway enrichment analysis revealed that these target genes were mainly enriched in alpha-linolenic acid and linoleic acid metabolism, ether lipid metabolism, VEGF signaling pathway, Fc epsilon RI signaling pathway, GnRH signaling pathway, and MAPK signaling pathway (P < 0.05). The regulatory role of miR-34a was more significant in the liver than in the brain of M. amblycephala. MiR-34a regulates glucose lipid homeostasis induced by high glucose diets by upregulating hepatic PI3K/Akt, FOXO, and TOR signaling pathways.
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